scholarly journals Qualitative and quantitative estimation of Diosgenin in coded ayurvedic formulation and its ingredient Trigonella foenum-graecum Linn. seeds used in diabetics

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ajay Kumar Meena ◽  
K. N. Swathi ◽  
R. Ilavarasan ◽  
Arjun Singh ◽  
Vandana Bharthi ◽  
...  
Keyword(s):  
Human Body ◽  
Quantitative Estimation ◽  
Health Conditions ◽  
Antidiabetic Activity ◽  
Leguminous Plant ◽  
Qualitative And Quantitative ◽  
Trigonella Foenum Graecum ◽  
Steroid Sapogenin ◽  
The Family ◽  
Loss Of Appetite

Abstract Background Trigonella foenum-graecum (Methi) is a leguminous plant and botanically known as Trigonella foenum-graecum Linn, belong to the family Fabaceae. Trigonella foenum-graecum is used for a variety of health conditions, including digestive problems, bronchitis, tuberculosis, fevers, sore throats, wounds, arthritis, abscesses, swollen glands, skin irritations, diabetes, loss of appetite, ulcers, and menopausal symptoms, as well as in the treatment of cancer. Trigonella foenum-graecum seeds mainly contain Diosgenin [(3β,25R)-spirost-5-en3-ol], a plant-derived steroid sapogenin. Results The identification and quantification results by HPTLC and HPLC studies of Trigonella foenum-graecum seeds hydrolysed Trigonella foenum-graecum seeds, coded formulation, hydrolysed coded formulation extract with standard Diosgenin biomarker showed a significant highest peak in hydrolysed Trigonella foenum-graecum seeds and hydrolysed coded formulation. The standard Diosgenin is observed in the hydrolysed form of hydrolysed Trigonella foenum-graecum seeds and hydrolysed coded formulation. The literature on Trigonella foenum-graecum confirms its activity as antidiabetic, and the peak of standard biomarker Diosgenin is seen after derivatization with anisaldehyde sulphuric agent, which possesses medicinal phytoconstituents value. Further related to future scientific aspects, more studies on its potent antidiabetic activity and multipurpose action need to be carried out with medicinal composition and its effects on the human body. Conclusion This study aims to establish the qualitative and quantitative estimation of standard Diosgenin in reliable with coded ayurvedic formulation and Trigonella foenum-graecum seeds and its activity as antidiabetic by HPTLC and HPLC.

QUALITATIVE AND QUANTITATIVE PHYTOCHEMICAL SCREENING AND IN VITRO ANTIOXIDANT EVALUATION OF PERGULARIA DAEMIA

2018 ◽  
Vol 24 (2) ◽  
Author(s):  
GITA MISHRA ◽  
HEMESHWER KUMAR CHANDRA ◽  
NISHA SAHU ◽  
SATENDRA KUMAR NIRALA ◽  
MONIKA BHADAURIA
Keyword(s):  
Reducing Sugars ◽  
Antioxidant Properties ◽  
Phytochemical Analysis ◽  
Phytochemical Screening ◽  
Qualitative And Quantitative ◽  
The Family ◽  
Ethanolic Extracts ◽  
Antioxidant Evaluation ◽  
In Vitro Antioxidant Activity

Pergularia daemia belongs to the family Asclepiadaceae, known to have anticancer, anti-inflammatory activity. Aim of the present study was to evaluate qualitative and quantitative phytochemical and antioxidant properties of ethanolic extracts of leaf, stem and root parts of P. daemia . Preliminary phytochemical analysis and in vitro antioxidant properties were evaluated by standard methods. The qualitative phytochemical analysis of P. daemia showed presence of flavonoids, tannins, alkaloid, phytosterol, carbohydrate, phenol, saponin, glycosides, terpenoids, steroids proteins and reducing sugars. Quantitative analysis showed polyphenol, flavonoid, flavonone, flavone and flavonol in P. daemia leaves, stem and root in considerable quantity. The in vitro antioxidant activity of P. daemia clearly demonstrated that leaf, stem and root parts have prominent antioxidant properties and was effective in scavenging free radicals.

scholarly journals Family risk as adjunct for organizing the demand for oral health service in the Family Health Strategy

2015 ◽  
Vol 44 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Henri Menezes Kobayashi ◽  
Antonio Carlos Pereira ◽  
Marcelo de Castro Meneghim ◽  
Rívea Inês Ferreira ◽  
Glaucia Maria Bovi Ambrosano
Keyword(s):  
Primary Care ◽  
Oral Health ◽  
Multinomial Logistic Regression ◽  
Family Health ◽  
Health Conditions ◽  
Family Risk ◽  
Treatment Needs ◽  
Health Strategy ◽  
The Family ◽  
Family Health Strategy

Introduction One of the main problems of the public health services, in which the family oral health team is included, is access by users to dental treatment in primary care, with particular reference to caries disease. Objective The aim of this study was to evaluate the relationship between family risk, for prioritization of home visits and oral health conditions, with a view to providing evidence about the first indicator for organizing the demand for oral health in the Family Health Strategy (FHS). Method The application of family health is based on Form A of the primary care information database SIAB ("Sistema de Informação de Atenção Básica"), used for registering families with the FHS. Eleven dentists examined the oral health conditions of 1165 persons (608 from 12 to 19 years; and 557 from 35 to 44 years of age), classifying them into six codes from A to F. Multinomial logistic regression was used (α=0.05) to analyze the association between family risk variables and oral health situation. Result There was significant association between family risk and presence of caries disease with treatment needs (OR: 2.08, p<0.0001). Conclusion Persons who have family risk would have twice as much chance of presenting caries disease in comparison with those without risk, corroborating the relevance of this element in organizing the demand for oral health.

scholarly journals The Active Role of Leguminous Plant Components in Type 2 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Monika Gętek ◽  
Natalia Czech ◽  
Małgorzata Muc-Wierzgoń ◽  
Elżbieta Grochowska-Niedworok ◽  
Teresa Kokot ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Bioactive Compounds ◽  
International Diabetes Federation ◽  
Noncommunicable Diseases ◽  
Antidiabetic Activity ◽  
Leguminous Plant ◽  
Morbidity Rate ◽  
Diabetes Incidence ◽  
Leguminous Plants

Diabetes appears to be one of the most frequent noncommunicable diseases in the world. A permanent growth in the incidence of diabetes can be observed and according to the International Diabetes Federation (IDF) the year 2030 will mark the increase in the number of diabetics to 439 mln worldwide. Type 2 diabetes accounts for about 90% of all diabetes incidence. Nutrition model modification not only features the basic element in type 2 diabetes treatment but also constitutes the fundamental factor influencing a morbidity rate decrease. Leguminous plants are a key factor in the diabetic diet; plants such as pulses or soybeans are nutritious products valued highly in nutrition. These legumes are high in the content of wholesome protein and contain large amounts of soluble alimentary fiber fractions, polyunsaturated fatty acids, vitamins and minerals, and bioactive substances with antioxidant, anti-inflammatory, and anticancer activity. They are distinguished by the high amount of bioactive compounds that may interfere with the metabolism of glucose. The most significant bioactive compounds displaying antidiabetic activity in leguminous plants are as follows: genistein and daidzein, alpha-amylase inhibitors, and alpha-glucosidase inhibitors.In vitroresearch using leguminous plant extracts has confirmed their antidiabetic properties. Leguminous plants should be employed in the promotion of healthy lifestyles in terms of functional food.

scholarly journals Qualitative and quantitative determination of phytochemicals from flowers of Spanish Cherry tree

2018 ◽  
Vol 8 (6-s) ◽  
pp. 182-186
Author(s):  
Vineeta Singh ◽  
Anita Rao ◽  
Shipra Pandey ◽  
Vaibhav Sharan Pandey ◽  
Vageshwari Vageshwari ◽  
...  
Keyword(s):  
Quantitative Determination ◽  
Quantitative Estimation ◽  
Standard Procedure ◽  
Tannin Content ◽  
Cherry Tree ◽  
Qualitative And Quantitative ◽  
Standard Curve ◽  
Soxhlet Apparatus ◽  
Percentage Yield

The present enquiry was intended to analyze the phytochemicals qualitatively and quantitatively from flowers of Spanish cherry tree. Flower powder was extracted using polar and nonpolar solvent by soxhlet apparatus. Percentage yield of crude extracts was determined and further the extracts were subjected to analyze the phytochemicals qualitatively and quantitatively by standard procedure. Qualitative analysis showed the absence of alkaloids while presences of tannins, saponins, terpenoids, steroids, glycosides, flavonoids, phenols. Quantitative estimation of phytochemicals was determined using standard curve. Result revealed that the tannin content was 4.3±0.01 (mgTAE /gm), flavanols content was 0.28±0.05 (mgQE/gm). Saponins content was 3.6±0.7 % and terpenoids content was 1.47±0.37 %. A well conducted studies on phytochemicals revealed that they are vital for humans because they provide protection against a variety of ailments. Therefore, the present study is aimed to analyze phytochemicals qualitatively and quantitatively. Keywords: Phytochemicals, Tannins, Saponins, Flavanols, Terpenoids

scholarly journals ON MULTIVARIATE APPROACH TO EVALUATE THE PROTECTION OF AQUIFERS AT DEVELOPMENT OF WESTERN SIBERIA OIL-AND-GAS BEARING AREAS

2015 ◽  
pp. 7-15
Author(s):  
Yu. V. Bespalova
Keyword(s):  
Quantitative Assessment ◽  
Western Siberia ◽  
Oil And Gas ◽  
Quantitative Estimation ◽  
Water Levels ◽  
Multivariate Approach ◽  
Qualitative And Quantitative ◽  
Ground Waters ◽  
Clay Rocks ◽  
Gas Bearing

The qualitative and quantitative assessment of ground waters protectability based on the regional specific charac-teristics of the lithology and thickness of impermeable deposits of the zone of aeration and overlying deposits, a ratio of confined and ground water levels, the soils and clay rocks absorptivity. The article gives the author's vision of ground waters natural protectability. It presents a quantitative estimation by three most well-known methods. Based on the calculations made a map of protectability of fresh ground waters in the Atlym-Novomikhailovsk complex for Nizhnevartovsk district was constructed.

scholarly journals “Pharmaco-chemical Characterization and Evaluation of In Vitro Antioxidant and Antidiabetic Activity of Ethanolic Flower Extract of Clerodendrum paniculatum”

2020 ◽  
Vol 11 (3) ◽  
pp. 4569-4577
Author(s):  
Sincy Varghese ◽  
Kanakasabapathi Devaki ◽  
Poornima Kannappan ◽  
Sri Rashmy Madathil
Keyword(s):  
Secondary Metabolites ◽  
Plant Material ◽  
Quantitative Estimation ◽  
Chemical Characterization ◽  
Antidiabetic Activity ◽  
Flower Extract ◽  
Ms Analysis ◽  
Ic50 Value ◽  
Biochemical Features

Quantitative and qualitative analysis of different components and antioxidant and activities of the extract of flower (CPF) were analyzed in . identification of of flower was also identified by GC-MS analysis. assess the biochemical features of CPF. solvent extraction of CPF was performed using solvents in increasing order of polarity (petroleum ether, chloroform, ethyl acetate, ethanol, and water) and solvent with maximum profile was standardized for further analysis. Quantitative analysis of selected secondary metabolites like tannin, , alkaloids, and of the flower extract was done by UV . In antioxidant assays and in efficacy of the flower extract were analyzed by respective in assays. identification of in CPF was identified by using GC-MS analysis revealed secondary metabolites in the extract, and further analysis of the extract was performed. Quantitative estimation revealed an accountable amount of secondary metabolites like (47.66mg/g acid equivalent), (24mg/g equivalent), (41mg/g equivalent), and alkaloids (1.79mg/g of extracted plant material). analysis (GC-MS) also confirmed convincing compounds in the extract. From in antioxidant and assay, the IC50 value of the extract of CPF was measured and compared with standard, and from the results, it was evident that the extract had significant in antioxidant and activity. the above results, it can be confirmed thatCPF has got significant and therapeutically active ingredients, as evident in analysis. This is further supported by considerable antioxidant and properties observed in respective assays.

scholarly journals Protective effects of Trigonella foenum-graecum crude extract over damage induced by Sreptozotocin diabetes rats

2020 ◽  
Vol 10 (4-s) ◽  
pp. 138-141
Author(s):  
Dalila Bencheikh ◽  
Seddik Khennouf ◽  
Saliha Dahamna
Keyword(s):  
Streptozotocin Diabetes ◽  
Diabetic Rats ◽  
Antidiabetic Activity ◽  
Protective Effects ◽  
Traditional Use ◽  
Orogastric Tube ◽  
Trigonella Foenum Graecum ◽  
Male Wistar Rats ◽  
Treatment Of Diabetes

The seeds of Trigonella foenum-graecum (fenugreek) are used for treatment of diabetes mellitus in traditional medicine. This paper examines the protection effects of fenugreek from the damage induced by streptozotocin diabetes rats. Tannins content of T. foenum-graecum was also estimated in vitro. Normoglycemic male Wistar rats, weighing 170-250 g, were selected and randomly divided into five groups (n= 6): normal control, diabetic + TFGE (200mg/kg), diabetic+ TFGE (600mg/kg), diabetic + Glibil (3mg/kg), untreated group. Diabetes was induced after a single intraperitoneal injection of streptozotocin (50 mg/kg body weight) and Fenugreek was given every day via orogastric tube for 18 days. At the end of experiment, rats were sacarificed. Organ weight was estimated of all groups. Trigonella foenum-graecum administration significantly improved the polydipsia, polyphagia, and it also compensated weight loss of diabetic rats (P<0.05, P < 0.01). Moreover, fenugreek had a significant concentration of tannins (806.22 ±0.036 µg TAE/gE). The results revealed that fenugreek improves the damage in diabetic rats that in some ways validates the traditional use of this plant in treatment of diabetes. Keywords: Antidiabetic activity, Protective effect, Streptozotocin, Tannins, Trigonella foenum-graecum

scholarly journals Efektifitas SUSCATIN dalam Membentuk Keluarga yang Sakinah Mawaddah Wa Rahmah

2019 ◽  
Vol 5 (1) ◽  
pp. 114-129
Author(s):  
Muhammad Al Faruq
Keyword(s):  
Research And Development ◽  
Quantitative Research ◽  
Qualitative Data ◽  
Director General ◽  
Qualitative And Quantitative ◽  
The Family ◽  
Harmonious Family

Abstract Ministry of Religious initiatives to implement the program in accordance with the regulations issued by the Director-General of Islamic Community guidance of the Department of Religious candidates for the No. DJ. II/491 Year 2009. Therefore, the quality of a marriage is determined by the readiness and maturity of the two prospective spouses to meet the life of the household in order to form a harmonious family in accordance with the premarital ideals. The research uses Research and Development (R&D) methods by combining qualitative and quantitative research. Qualitative data is obtained through verbal and written interview results. The problems that occur in the community that the effectiveness of the prospective bride course has not walked fully well, with a variety of factors that inhibit, so that the bride who has not understood the whole material about the concept of family Sakinah that has been poured in the course process Bride brides. For that, the research seeks to uncover the implementation of the bride candidate course at the Office of Religious Affairs (KUA) of Papar District of Kediri, as well as how the prospective bride understanding the family concept of Sakinah.

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