Adjustment disorder or adaptive adjustment?

2020 ◽  
pp. 1-2
Author(s):  
Patricia Casey

SUMMARY The differentiation of pathological stress responses from responses that are appropriate and adaptive is a challenge with little to guide the clinician. This refreshment considers adjustment disorder and possible approaches to distinguishing those who have the disorder from those who are responding ‘normally’ to stressful events.

Animals ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 204 ◽  
Author(s):  
Rosaria Marino ◽  
Mariangela Caroprese ◽  
Giovanni Annicchiarico ◽  
Francesco Ciampi ◽  
Maria Ciliberti ◽  
...  

In the last years several studies have investigated the strong relation between nutrition and immune response in the livestock production, particularly in dairy cattle and sheep. The aim of this study was to evaluate the effects of supplementation based on linseed, quinoa seeds and their combination on welfare, productivity and quality of meat from merinos derived lambs. 32 weaned lambs were divided into 4 experimental groups: quinoa (Q), linseed (LS) and combination of quinoa and linseed (LS + Q) that received the respective supplementation and control group (C) without supplementation. Lambs from all supplemented groups showed lower plasma urea, creatinine and cholesterol than control. Both linseed and quinoa supplementation enhanced the cell-mediated immune responses of lambs, furthermore, linseed supplementation resulted in the lowest level of cortisol secretion after handling, loading and transport. Meat from lambs supplemented with linseed and LS + Q showed the highest pH, at 1 and 3 h post-mortem, while, meat from all supplemented groups was more tender than meat from control. Results indicated that linseed and quinoa seeds supplementation can help the animal to cope with stressful events due to the close link between stress responses and the immune system and for improving meat quality in terms of better tenderness.


Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 358 ◽  
Author(s):  
Angelo Peli ◽  
Annamaria Grandis ◽  
Marco Tassinari ◽  
Paolo Famigli Bergamini ◽  
Claudio Tagliavia ◽  
...  

Calves reared for the production of white veal are subjected to stressful events due to the type of liquid diet they receive. Stress responses are mediated by three main stress-responsive cerebral regions: the prefrontal cortex, the paraventricular nucleus of the hypothalamus, and the nucleus of the solitary tract of the brainstem. In the present study, we have investigated the effects of different diets on these brain regions of ruminants using immunohistochemical methods. In this study, 15 calves were used and kept in group housing systems of five calves each. They were fed with three different diets: a control diet, a milk diet, and a weaned diet. Brain sections were immunostained to evaluate the distribution of neuronal nitric oxide synthase and myelin oligodendrocyte glycoprotein immunoreactivity in the prefrontal cortex; the expression of oxytocin in the paraventricular nucleus; and the presence of c-Fos in the A2 group of the nucleus of the solitary tract. The main results obtained indicate that in weaned diet group the oxytocin activity is lower than in control diet and milk diet groups. In addition, weaning appears to stimulate myelination in the prefrontal cortex. In summary, this study supports the importance of maintaining a nutritional lifestyle similar to that occurring in natural conditions.


BJPsych Open ◽  
2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Menachem Ben-Ezra ◽  
Wai Kai Hou ◽  
Robin Goodwin

Background To assess the prevalence of elevated risk of serious mental illness and probable ICD-11 adjustment disorder in the UK population at two time points during COVID-19, and their association with COVID-19-related stressful events. Aims To check the dose–response model for stress between the number of COVID-19-related stressful events and mental health indices. Method We conducted two cross-sectional studies, using internet survey samples across the UK (N = 1293 for study 1; N = 1073 for study 2). Samples used internet panel surveys during March–April 2020 and 3 months later (June 2020), and used random stratified samples. Studies assessed prevalence of serious risk of mental illness and probable ICD-11 adjustment disorder. Results Elevated risk of serious mental illness was found among those with COVID-19-related social life or occupationally stressful events (study 1). Elevated risk of serious mental illness and probable ICD-11 adjustment disorder was evident among those reporting COVID-19-related stressful events (personal health problems and caregiving; study 2). Cumulative COVID-19-related stressful events were associated with elevated risk of serious mental illness in study 1 (odds ratio 1.65; 95% CI 1.03–2.64; P = 0.037), and with both elevated risk of serious mental illness (odds ratio 2.19; 95% CI 1.15–4.15; P = 0.017) and probable ICD-11 adjustment disorder (odds ratio 2.45; 95% CI 1.27–4.72; P = 0.007) in study 2. Conclusions Psychiatrists should be aware that COVID-19-related stressful events can lead to serious psychological problems. Mental health professionals need to pay particular attention to patients who report cumulative COVID-19-related stressful events, and consider them for mental health assessment and treatment.


2006 ◽  
Vol 59 (3-4) ◽  
pp. 149-154 ◽  
Author(s):  
Nedeljko Platisa ◽  
Gordana Devecerski

The aim of this study was to establish types of psychological reactions and conditions in patients with lower-extremity amputations. Apart from using psychological interviews, detection was performed using psychometric tests: Minnesota Multiphasic Personality Inventory and Beck Depression Inventory. Psychometric parameters were analyzed in a group of 20 examinees treated at the Medical Rehabilitation Clinic in Novi Sad. Out of the whole sample. 45% of patients presented with adaptive reactions to amputation and consequent disability, whereas 55% presented with maladaptive responses. The registered psychopathological symptoms included nosologic categories: reaction to stressful events and adjustment disorder (predominantly affecting other emotions: mixed disorder of conduct and emotions: prolonged depressive reaction) and dysthymia. When working with lower-extremity amputees, apart from adaptive, nonpathological forms of behavior, one also encounters maladaptive responses with predomination of mood disorders due to severe somatic stress. .


2021 ◽  
Author(s):  
David Yeager ◽  
Christopher Bryan ◽  
James Gross ◽  
Danielle Krettek ◽  
Pedro Santos ◽  
...  

Abstract Social stress poses a major threat to adolescent health via its effects on internalizing symptoms, such as anxiety and depression. Available interventions to help adolescents improve their stress responses, however, have not been effective in rigorous evaluation studies, or they have been difficult to administer widely. Here we show that replicable improvements in adolescent stress responses can be achieved with a short (~30-minute), scalable synergistic mindsets intervention. This intervention, which is a self-administered online training module, targets both growth mindsets (the idea that people’s intelligence can be developed in response to challenge) and stress-can-be-enhancing mindsets (the idea that people’s stress responses can be fuel for optimal performance). Its goal is to promote positive engagement with stressful events (e.g., learning from failure on a quiz or a conflict with a peer) and to encourage adolescents to use their responses to stressful events and even their bodily symptoms (e.g. racing heart, sweaty palms, butterflies in their stomach) to their advantage. In five double-blind, randomized, controlled trials (total N = 4,091 adolescents), the new synergistic mindsets intervention improved stress-related cognitions (Studies 1-2), cardiovascular reactivity (Study 3), daily internalizing symptoms and cortisol levels (Study 4), and generalized anxiety symptoms during the 2020 COVID-19 lockdowns (Study 5). Effects on downstream outcomes (in Studies 3-5) were stronger among individuals who, at baseline, held the two negative mindsets targeted by the intervention, providing evidence for the proposed mechanisms. Confidence in this conclusion comes from a conservative, Bayesian machine-learning method for detecting heterogeneity.


2021 ◽  
Vol 5 (1) ◽  
pp. 124-134
Author(s):  
Lisa-Marie Rückel ◽  
Benjamin Noël ◽  
André Jungen ◽  
Sebastian Brückner ◽  
Bernd Strauss ◽  
...  

This study uses a thematic content analysis to analyze common stressors for volleyball referees, examine the individual triggered stress responses, and identify the applied coping strategies. A total of 38 German elite volleyball referees (24 male and 14 female, Mage = 38.29 years, SD = 7.91 years) were considered for this study. Through the analysis, 17 stressful events, 14 stress responses, and 6 different coping strategies were identified and further clustered into four main dimensions. Common stressors among elite German volleyball referees were identified as stressful game situations, need for game management, situational environment, and demands on self-activation. These stressors triggered emotional stress reactions, cognitive stress reactions, changes in focus, and reactions among the test group after increased strain. In order to deal with these situations and emotions, referees applied self-regulation strategies, improved focus and concentration, searched for a solution, prepared for the match or a stressor, showed a confident appearance, and tried to accept and let go of mistakes or situations. Post hoc Pearson’s correlation analyses showed significant relationships between emotional and cognitive stress reactions with stressful game situations. Consequently, the role of coping with emotions and thoughts becomes essential for volleyball referees to remain focused and perform.


1986 ◽  
Vol 59 (2) ◽  
pp. 575-583 ◽  
Author(s):  
Charles H. Morgan ◽  
Dean W. Owen ◽  
Arden Miller ◽  
Martha L. Watts

Prior research shows wide individual differences in perception of and response to stressful life events. The present study examined the extent to which those differences could be attributable to individual differences in one's feelings of general self-efficacy or to characteristic ways of attributing causality for possible successful resolution of the problem posed. A sample of 273 undergraduate students were surveyed to ascertain their estimates of the stressfulness of four of 16 stressful life events as well as their attributions of the causality of successful resolution and the individuals' scores on the Self-efficacy Scale. Subjects' ratings of stressfulness were quite consistent regardless of the specific definition of stress used, were significantly, but at a low level, related to felt self-efficacy, and were inconsistently related to attributional characteristics. Further directions for research in the situational and individual interaction in assessing the impact of stressful events are suggested.


Author(s):  
H E Yarur ◽  
J Zegers ◽  
I Vega-Quiroga ◽  
J Novoa ◽  
F Ciruela ◽  
...  

Abstract Background Basolateral amygdala (BLA) excitatory projections to medial prefrontal cortex (PFC) play a key role controlling stress behavior, pain, and fear. Indeed, stressful events block synaptic plasticity at the BLA-PFC circuit. The stress responses involve the action of corticotrophin releasing factor (CRF) through type 1 and type 2 CRF receptors (CRF1 and CRF2). Interestingly, it has been described that dopamine receptor 1 (D1R) and CRF peptide have a modulatory role of BLA-PFC transmission. However, the participation of CRF1 and CRF2 receptors in BLA-PFC synaptic transmission still is unclear. Methods We used in vivo microdialysis to determine dopamine and glutamate (GLU) extracellular levels in PFC after BLA stimulation. Immunofluorescence anatomical studies in rat PFC synaptosomes devoid of postsynaptic elements were performed to determine the presence of D1R and CRF2 receptors in synaptical nerve endings. Results Here, we provide direct evidence of the opposite role that CRF receptors exert over dopamine extracellular levels in the PFC. We also show that D1R colocalizes with CRF2 receptors in PFC nerve terminals. Intra-PFC infusion of antisauvagine-30, a CRF2 receptor antagonist, increased PFC GLU extracellular levels induced by BLA activation. Interestingly, the increase in GLU release observed in the presence of antisauvagine-30 was significantly reduced by incubation with SCH23390, a D1R antagonist. Conclusion PFC CRF2 receptor unmasks D1R effect over glutamatergic transmission of the BLA-PFC circuit. Overall, CRF2 receptor emerges as a new modulator of BLA to PFC glutamatergic transmission, thus playing a potential role in emotional disorders.


Author(s):  
D. M. Tilbury ◽  
B. T. Felt ◽  
N. Kaciroti ◽  
L. Wang ◽  
T. Tardif

This paper presents preliminary results for using dynamic systems models to describe cortisol responses to stressful events. Linear, single-input single-output discrete-time models are used. Choices that must be made regarding interpolation and input modeling are discussed in some detail. Results are presented that indicate an impulse model for the stressful input gives a better fit than no input, and that logarithmic transformation of the data before model fitting gives no better results than using the raw data. The issue of stability of the resulting models is discussed. In addition, the paper discusses how the resulting dynamic systems models can be used for statistical analysis, as well as for predicting future stress responses.


2012 ◽  
Vol 201 (2) ◽  
pp. 90-92 ◽  
Author(s):  
Patricia Casey ◽  
Anne Doherty

SummaryAdjustment disorder has been a recognised disorder for decades but has been the subject of little epidemiological research. Now researchers have identified the prevalence of adjustment disorder in primary care, and found general practitioner recognition very low but with high rates of antidepressant prescribing. Possible reasons for the seemingly low prevalence, recognition rate and inappropriate management include its recognition as a residual category in diagnostic instruments and poor delineation from other disorders or from normal stress responses. These problems could be rectified in ICD-11 and DSM-5 if changes according it full syndromal status, among others, were made. This would have an impact on future research.


Sign in / Sign up

Export Citation Format

Share Document