The Natural History of Mental Disorder in Old Age

1955 ◽  
Vol 101 (423) ◽  
pp. 281-301 ◽  
Author(s):  
Martin Roth

Our classification of the mental disorders of later life, which are becoming a social and medical problem of increasing magnitude, is still based upon the views of the great descriptive psychiatrists of half a century ago. Most of the classical accounts of mental disorder of old age (Kraepelin, 1909; Bleuler, 1916) confine themselves to the pre-senile, senile and arteriosclerotic psychoses. Their writers evidently regarded other illnesses as numerically insignificant in relation to these degenerative disorders peculiar to old age. Cases with a predominantly depressive or paranoid picture or with clouding of consciousness alone were described in these old accounts, but were attributed to an underlying cerebral illness, either of senile or arteriosclerotic type. It is consequently a long-established practice when such symptoms appear for the first time in old age, or occur in senescence after prolonged remission, to search for neurological signs, or for some evidence of a decline in intellectual efficiency which might account for the illness in terms of organic disease of the brain. Weight is thus often given to clinical findings of a quite subtle character, or the results of “deterioration tests” whose value in the early diagnosis of degenerative processes in the brain is unproven, form the basis of conclusions of doubtful validity.

2020 ◽  
Vol 15 (2) ◽  
pp. 68
Author(s):  
А. Н. Сухов

This given article reveals the topicality not only of destructive, but also of constructive, as well as hybrid conflicts. Practically it has been done for the first time. It also describes the history of the formation of both foreign and domestic social conflictology. At the same time, the chronology of the development of the latter is restored and presented objectively, in full, taking into account the contribution of those researchers who actually stood at its origins. The article deals with the essence of the socio-psychological approach to understanding conflicts. The subject of social conflictology includes the regularities of their occurrence and manifestation at various levels, spheres and conditions, including normal, complicated and extreme ones. Social conflictology includes the theory and practice of diagnosing, resolving, and resolving social conflicts. It analyzes the difficulties that occur in defining the concept, structure, dynamics, and classification of social conflicts. Therefore, it is no accident that the most important task is to create a full-fledged theory of social conflicts. Without this, it is impossible to talk about effective settlement and resolution of social conflicts. Social conflictology is an integral part of conflictology. There is still a lot of work to be done, both in theory and in application, for its complete design. At present, there is an urgent need to develop conflict-related competence not only of professionals, but also for various groups of the population.


2021 ◽  
Vol 27 (3) ◽  
pp. 148-154
Author(s):  
Natalia A. Guz ◽  
Yulia G. Babicheva

The purpose of the work is to explore the point of view in Vasily Shukshin's short stories in its systematic and diverse manifestation. Topicality is provided by the exceptional significance of this category in narratology. The study of the point of view based on the material of short stories by Vasily Shukshin has been conducted for the first time. The article briefly traces the history of scientific understanding of the category of point of view in foreign and Russian philology and notes the variety of approaches and definitions in the formulation of the concept. The authors use the classification of Boris Uspenskij for analysis and consider the point of view in Vasily Shukshin's short stories in psychological, ideological (evaluative), spatial-temporal and phraseological terms. The positions of Boris Korman, Yuri Lotman, Wolf Schmid and Franz Karl Stanzel also take into account. The authors note the features of Vasily Shukshin's narration that affect the expression of the point of view in the text. Vasily Shukshin's short stories are characterised by a dynamic and frequent change of points of view, which indicates the technique of “montageˮ and similarities in this regard with cinematic techniques. The conclusions generalise the variety of ways and forms of expression of the point of view in the studied artistic material. The point of view in the considered stories is characterised by variability in the correlation of subjects of speech and subjects of consciousness, alternation of external and internal points of view, mutual transitions from one to the other, text interference and other hybrid phenomena.


2019 ◽  
Vol 5 (1) ◽  
pp. 205511691983185
Author(s):  
Lisa Graziano ◽  
Stefania Di Paco ◽  
Giancarlo Avallone ◽  
Paola Roccabanca

Case summary A 10-year-old male neutered domestic shorthair cat was presented with a 4 month history of slow, progressive swelling and intermittent multifocal bleeding of the distal right forepaw that progressively developed after cephalic vein catheterisation for anaesthesia. The procedure was performed for dental calculus removal. Initial clinical and biopsy (superficial biopsy) findings matched two differential diagnoses: progressive angiomatosis and acquired peripheral arteriovenous fistula (AVF). AVF was suspected based on Doppler ultrasound examination that identified multiple abnormal sinusoidal neoformed branching vessels with turbulent high-velocity flow spectrum at the confluence of the artery and vein, and high-velocity arterialised flow in the vein. Owing to rapid and severe progression of lesions after biopsy, the owner requested amputation of the cat’s limb. A definitive diagnosis of acquired iatrogenic peripheral AVF was based on deep-tissue microscopical evaluation. High numbers of arterioles and venules in superficial and deep dermis embedded in oedematous stroma were connected to dilated and tortuous vessels with irregularly thickened walls in deep dermis and panniculus. Vasculitis and vascular thrombosis and thickening (attributed to local hypertension) were common findings. No bone or muscular invasion were observed. The cat was doing well 3 years after surgery. Relevance and novel information This report describes a case of iatrogenic acquired peripheral AVF following venous catheterisation in a cat, fully documented for the first time by a combination of clinical findings, ultrasound imaging, complete histopathology and follow-up history.


1996 ◽  
Vol 2 (3) ◽  
pp. 133-139
Author(s):  
A. Phanjoo

Psychotic disorders in the elderly can be divided into three types: disorders that have started in earlier life and persist into old age; disorders that start de novo after the age of 60, and psychoses associated with brain disease, including the dementias. The classification of psychoses in late life has provoked controversy for nearly a century. The debate concerns whether schizophrenia can present at any stage of life or whether functional psychoses, arising for the first time in late life, represent different illnesses. The nomenclature of such disorders consists of numerous terms including late onset schizophrenia, late paraphrenia, paranoid psychosis of late life and schizophreniform psychosis. This plethora of terms has made research difficult to interpret.


Author(s):  
Dr. Nagaraju. K. S

Abstract: People have been taking the drug in various forms for many years for enjoyment, relaxation, sleeping, stimulation, or another reason. In the starting, people takes the drug for taste and alter the consciousness, behavior, mood, and thoughts but he/she becomes habitual and dependent on any substance use disorder such as alcohol, tobacco, cannabis, ecstasy, cocaine, methamphetamine, and heroin, amphetamines, or illegal drugs. As per my thoughts and watching surroundings, if you ask a drug intake person “how do you become a drug addictive”? Most people will answer this “they started taking the drug in their friend circle, at relatives home or with relationship partner”. The first time they take it for taste or due to forcing by someone but after some time this becomes a habit. Peer pressure can fall you in this black world. Also, if someone has family history of addiction then he/she may chance to catch this addiction and make habitual others as well. So good friend circle really matters. Drugs such as heroin and marijuana are structured in the same way as chemical messengers known as neurotransmitters. These neurotransmitters are produced naturally by the human brain. As a result of this similarity, the drugs can fool the receptors of human brain and activate the nerve cells in such a way that they send some abnormal messages. In case of drugs like methamphetamine and cocaine, the nerve cells get activated and they release extraordinarily large volumes of neurotransmitters. They are also capable of preventing the brain from recycling these chemicals in a normal manner. A normal level of production is necessary in order to end the signal between neurons. Keywords: Alcohol – Beer, Wine, & Liquor, Opioids – Heroin, Fentanyl & Oxycodone, Cannabinoids – Marijuana & Hashish, Benzodiazepines – Ativan, Valium & Xanax, Stimulants – Adderall, Cocaine & Meth.


2019 ◽  
Vol 8 (5) ◽  
pp. 595 ◽  
Author(s):  
Leggieri ◽  
Attanasio ◽  
Palladino ◽  
Cellerino ◽  
Lucini ◽  
...  

Neurotrophins contribute to the complexity of vertebrate nervous system, being involved in cognition and memory. Abnormalities associated with neurotrophin synthesis may lead to neuropathies, neurodegenerative disorders and age-associated cognitive decline. The genome of teleost fishes contains homologs of some mammalian neurotrophins as well as a gene coding for an additional neurotrophin (NT-6). In this study, we characterized this specific neurotrophin in the short-lived fish Nothobranchius furzeri, a relatively new model for aging studies. Thus, we report herein for the first time the age-related expression of a neurotrophin in a non-mammalian vertebrate. Interestingly, we found comparable expression levels of NT-6 in the brain of both young and old animals. More in detail, we used a locked nucleic acid probe and a riboprobe to investigate the neuroanatomical distribution of NT-6 mRNA revealing a significant expression of the neurotrophin in neurons of the forebrain (olfactory bulbs, dorsal and ventral telencephalon, and several diencephalic nuclei), midbrain (optic tectum, longitudinal tori, and semicircular tori), and hindbrain (valvula and body of cerebellum, reticular formation and octavolateral area of medulla oblongata). By combining in situ hybridization and immunohistochemistry, we showed that NT-6 mRNA is synthesized in mature neurons. These results contribute to better understanding the evolutionary history of neurotrophins in vertebrates, and their role in the adult brain.


Author(s):  
Deborah T. Gold

ABSTRACTThis paper reports the findings of a qualitative examination of sibling relationships in old age. Interviews with sixty people over the age of sixty-five revealed that interactions with sisters and brothers took on new meaning in late life. A shared history of lifetime experiences made the sibling relationship unique in social networks in old age. Those who had positive relationships with siblings found that interactions decreased feelings of loneliness, provided emotional support and validation of earlier life experiences, and built feelings of closeness and sibling solidarity. Even those who had negative sibling relationships indicated a shift in feelings. The intensity of feeling about siblings in old age suggests that further study of the later-life sibling bond might increase understanding of ways in which the social and emotional needs of older people can be met. Interviews provided an effective method for gathering rich data about these complex social and emotional interactions.


1952 ◽  
Vol 98 (410) ◽  
pp. 66-80 ◽  
Author(s):  
Martin Roth ◽  
J. D. Morrissey

Recent statistics of old age mental disorder have drawn an alarming picture of rising rates of admission to mental hospitals in many parts of the world. One of the predictions made on the basis of such statistics has been that old age psychoses might, in due course, relegate schizophrenia to second place in number of admissions. There are, however, dangers in drawing conclusions about a complicated problem, such as mental disorder in old age, on statistical grounds alone. Before the figures can be properly evaluated more detailed information about the social, economic and, above all, clinical aspects of the problem will be required than is available at present.


1996 ◽  
Vol 84 (1) ◽  
pp. 133-142 ◽  
Author(s):  
Dee J. Canale

✓ The year 1993 marked the centennial of the publication of Sir William Macewen's monograph, Pyogenic Infective Diseases of the Brain and Spinal Cord, and its accompanying volume, Atlas of Head Sections. As Harvey Cushing noted, the text on pyogenic diseases of the brain was a landmark in surgery of the nervous system. At the time of its publication, Macewen's work was the most comprehensive study of pyogenic brain diseases. In this paper the author reviews the state of knowledge of brain abscess existing in the 19th and 20th centuries, with particular emphasis on the late 19th century, and elucidates factors contributing to Macewen's remarkable success. His thorough knowledge of the natural history of pyogenic diseases of the temporal bone and nasal sinuses, in addition to his clear description of cranial anatomy, as illustrated in his Atlas of Head Sections, were especially important in developing his successful treatment of brain abscess. The x-ray had not yet been discovered; Macewen's diagnosis was based on clinical findings superbly illustrated by his three clinical stages of brain abscess development. His clinical observations are as relevant today as when he described them 100 years ago. Macewen recorded 25 cases of brain abscess. Nineteen of these patients came to his attention in time to undergo surgery, resulting in 18 recoveries. All five of his patients with extradural abscess recovered. These results were achieved in the era known as “the most glorious period in British surgery.” Neurosurgery was in its infancy; nevertheless, even as the 20th century closes, Macewen's results still have not been surpassed.


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