Alcohol Advertising in Pacific Islands Countries and Territories: A Scoping Review

Introduction: Alcohol has become embedded into the cultural, economic, and social fabric of Pacific Island Countries and Territories (PICT); however, it continues to be a neglected health issue for many PICT. This scoping literature review explores current alcohol advertising policies in each PICT. Methods: This review utilises the 'Preferred Reporting Items for Systematic Review and Meta-Analyses for Scoping reviews' to identify literature on alcohol advertising policies. Twenty-five sources, ranging from 1963 to 2020, form the final data synthesis. Findings: The results of this review reveal that not all PICT have alcohol advertising restrictions in place. Health warning labels as a means of deterring alcohol use are also inconsistent across PICT but aid in consumer decisions. A notable concern in alcohol advertising is the use of culture as a marketing ploy. Conclusion: This review provides essential information on alcohol advertising in PICT. Nine PICT enforce some form of alcohol advertising prohibition, and ten do not. In countries with alcohol advertising, drinking behaviours vary, demonstrating a need for further research on the implementation efforts of current policies. In countries with no alcohol advertising, alcohol use is normalised and portrayed as unproblematic. The use of health warning labels is also not consistent amongst PICT. The use of culture as a marketing ploy is unacceptable as it belittles culture and is disrespectful to leaders. Understanding the alcohol advertising restrictions that work in each PICT can help decrease alcohol consumption and the harms associated with its misuse across all PICT. Keywords: Alcohol, Advertising, Pacific.

The Effect of Mouthrinses on Surface Roughness of Two Nanohybrid Resin Composites

Objective: The aim of this study was to evaluate the effect of four different mouthrinses on the surface roughness of two nanohybrid resin composites. Material and Methods: Fifty samples were prepared for each of the resin composites (2x8 mm) and a profilometer was used to determine the initial surface roughness (Ra) of each sample. Then, they were divided into 5 subgroups (n= 10), and exposed to the following mouthrinses (12h, 37 ºC): containing alcohol and essential oils; alcohol and chlorhexidine; alcohol-free and essential oils; alcohol free and cetil prydinium chlorite; or distilled water (control). The surface roughness of each sample was measured again. Statistical analyses of the data were performed via two-way ANOVA and Bonferroni tests. Results: Overall, statistically significant differences were not found between the resin composites (p> 0.05), but significant differences were found among the mouthrinses (p< 0.05). Interactions between the mouthrinses and the resin composites was statistically significant (p< 0.05). Both of the resin composites had the highest surface roughness after exposure to mouthrinse with alcohol and essential oils (p< 0.05), followed by mouthrinse with alcohol and chlorhexidine. Both alcohol-free mouthrinses caused surface roughness either similar to distilled water (p> 0.05) or lower than distilled water (p< 0.05) on the nanohybrid resin composites used. Conclusion: The mouthrinses affected the surface roughness of the resin composites in different ways. This was dependent on mouthrinse contents and the chemical structure of the resin composites. Alcohol-containing mouthrinses caused the most changes in the surface roughness of both resin composites. Keywords Alcohol; Chlorhexidine; Composite resin; Essential oil; Roughness.

A Brief Analysis About the Drug Addiction by Youths in India

People have been taking the drug in various forms for many years for enjoyment, relaxation, sleeping, stimulation, or another reason. In the starting, people takes the drug for taste and alter the consciousness, behavior, mood, and thoughts but he/she becomes habitual and dependent on any substance use disorder such as alcohol, tobacco, cannabis, ecstasy, cocaine, methamphetamine, and heroin, amphetamines, or illegal drugs. As per my thoughts and watching surroundings, if you ask a drug intake person “how do you become a drug addictive”? Most people will answer this “they started taking the drug in their friend circle, at relatives home or with relationship partner”. The first time they take it for taste or due to forcing by someone but after some time this becomes a habit. Peer pressure can fall you in this black world. Also, if someone has family history of addiction then he/she may chance to catch this addiction and make habitual others as well. So good friend circle really matters. Drugs such as heroin and marijuana are structured in the same way as chemical messengers known as neurotransmitters. These neurotransmitters are produced naturally by the human brain. As a result of this similarity, the drugs can fool the receptors of human brain and activate the nerve cells in such a way that they send some abnormal messages. In case of drugs like methamphetamine and cocaine, the nerve cells get activated and they release extraordinarily large volumes of neurotransmitters. They are also capable of preventing the brain from recycling these chemicals in a normal manner. A normal level of production is necessary in order to end the signal between neurons. Keywords: Alcohol – Beer, Wine, & Liquor, Opioids – Heroin, Fentanyl & Oxycodone, Cannabinoids – Marijuana & Hashish, Benzodiazepines – Ativan, Valium & Xanax, Stimulants – Adderall, Cocaine & Meth.

Hepatocytes Protection by Vitamin E in Alcoholic Liver Injury: A Light Microscopic Study

Background: Alcohol induces histomorphological changes in the liver and vitamin E has a protective role against these changes. Objective: To observe changes in hepatocytes of rabbits exposed to intragastric administration of alcohol and the protective role of vitamin E against these changes. Study Design: Analytical experimental study Place and Duration of Study: Department of Anatomy, Pathology and Pharmacology of Peshawar Medical College, Peshawar, Pakistan from 1st January 2016 to 30th June 2016. Methodology: Eighteen male rabbits domestic type (Oryctolaguscuniculus) were included. Experimental duration for category E8 animals was 8 weeks while for category E4 animals it was 4 weeks. The groups were, control group A in which animals were given proper food and normal saline as drinking water, experimental group B in which animals were fed on proper diet and 30% ethanol solution (30 ml/kg/day) orally daily with normal saline and experimental group C in which animals were treated with proper diet, 30% ethanol solution (30 ml/kg/day), vitamin E (50 mg/kg/day) orally daily and normal saline as drinking water. Results: The difference in the ALT, hepatocyte count and size and hepatocyte nuclear count and size of control and experimental groups and experimental group B-II and C-II from both category E4 and E8 showed a highly significant P values. Conclusion: Alcohol causes histomorphological changes in the liver even in the short period of 4-8 weeks and these changes can be minimized by the antioxidant action of vitamin E. Keywords: Alcohol, Liver, Histomorphology, Vitamin E, Hepatocyte, ALT

Automatic Alcohol Detection System

In pretty much every industry and field, innovation keeps on disturbing old frameworks and opening up new pathways. Not more so than in the field of law enforcement, where analysts, designers, and tech virtuosos are chipping away at further developed apparatuses not exclusively to uphold DUI, yet additionally to forestall it. Maybe the most encouraging of these drives is the Alcohol Safety Detection System, fostering an innovation that will consequently keep an intoxicated driver from driving an engine vehicle, an attempt will be made to fabricate a locking mechanism for vehicles so it would not begin without an Alcohol detection system. This paper portrays a driver alcohol concentration detection framework dependent on breath testing, created utilizing a microcontroller Compatible Compiler, that permits the program of microcontroller boards. The framework can gauge the liquor from the breath test and control the activity of the vehicle start framework to forestall smashed driving. Additionally, the utilization of virtual instrumentation gives high adaptability, in contrast to traditional methods. Drunken driving has become a significant problem in present-day culture. It is a typical reason for vehicle crashes including human mistakes. This venture focused on developing a system to prevent, in anticipation of making everyday traffic safe. Keywords: Alcohol safety detection system, MQ3 sensor, Arduino UNO.

Consequences of the Adopted Fatal Addictive Duplet

This review focus on strong association of smoking and alcohol use with a variety of adverse human health effects, most prominently with cancer and cardiovascular diseases and a number of negative outcomes as a risk factor for diseases and health impacts: crime, road incidence and for some, alcohol dependence. To keep track of alcohol consumption and smoking and its consequences and to raise awareness amongst the public and policy-makers, national monitoring systems to be developed. Tobacco smoking is highly prevalent throughout the world and is, perhaps, the greatest modifiable risk factor for increased morbidity and mortality. Physicians, Pharmacists, Nurses and other healthcare providers have substantial opportunities to influence the pattern of smoking and alcohol usage. Keywords: Alcohol, Smoking, Coronary Heart Disease, Hepatotoxicity, Cancer, Atherosclerosis, Cytochrome P450 enzymes, Alcohol-Drug Interactions, Smoking-Drug Interactions, Smoking and Alcohol Cessation.

Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland

Rehm, J., Rehm, M. X., Alho, H., Allamani, A., Aubin, H., Bühringerm G,m Daeppen, J., Frick, U., Gual, A., & Heather, N. (2013). Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland. International Journal of Alcohol and Drug Research, 2(2), 53-67. doi: 10.7895/ijadr.v2i2.89 (http://dx.doi.org/10.7895/ijadr.v2i2.89) Aim: To describe guidelines and common practices for alcohol dependence treatment in Europe. Design: Systematic and qualitative review; for each country, guidelines were identified via systematic literature research, followed by interviews with treatment experts. Setting: European Union (EU) countries plus Iceland, Norway, and Switzerland. Participants: Experts in alcohol dependence treatments and treatment systems. Measure: Semi-structured questionnaire for interviews. Findings: While fewer than half of EU countries have formal national guidelines for alcohol dependence treatment, a majority of these countries have guidelines by professional organizations such as psychiatric or neuropsychopharmacologic societies, and several are currently developing such guidelines. Abstinence is the usual treatment goal, but the majority of countries accept reduction of drinking as an intermediate or secondary goal, in practice even more than in the guidelines. Psychotherapy, mainly cognitive-behavioral approaches, motivational interviewing, and family therapy, is the most common treatment for relapse prevention, in part accompanied by pharmacotherapy (disulfiram, acamprosate and naltrexone being used most often). Conclusions: There are differences in treatment for alcohol dependence in Europe. The introduction of reduction of drinking as one treatment goal may attract more patients. Keywords alcohol dependence, treatment, abstinence, reduced drinking, pharmacotherapy

Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland

Rehm, J., Rehm, M. X., Alho, H., Allamani, A., Aubin, H., Bühringerm G,m Daeppen, J., Frick, U., Gual, A., & Heather, N. (2013). Alcohol dependence treatment in the EU: A literature search and expert consultation about the availability and use of guidelines in all EU countries plus Iceland, Norway, and Switzerland. International Journal of Alcohol and Drug Research, 2(2), 53-67. doi: 10.7895/ijadr.v2i2.89 (http://dx.doi.org/10.7895/ijadr.v2i2.89) Aim: To describe guidelines and common practices for alcohol dependence treatment in Europe. Design: Systematic and qualitative review; for each country, guidelines were identified via systematic literature research, followed by interviews with treatment experts. Setting: European Union (EU) countries plus Iceland, Norway, and Switzerland. Participants: Experts in alcohol dependence treatments and treatment systems. Measure: Semi-structured questionnaire for interviews. Findings: While fewer than half of EU countries have formal national guidelines for alcohol dependence treatment, a majority of these countries have guidelines by professional organizations such as psychiatric or neuropsychopharmacologic societies, and several are currently developing such guidelines. Abstinence is the usual treatment goal, but the majority of countries accept reduction of drinking as an intermediate or secondary goal, in practice even more than in the guidelines. Psychotherapy, mainly cognitive-behavioral approaches, motivational interviewing, and family therapy, is the most common treatment for relapse prevention, in part accompanied by pharmacotherapy (disulfiram, acamprosate and naltrexone being used most often). Conclusions: There are differences in treatment for alcohol dependence in Europe. The introduction of reduction of drinking as one treatment goal may attract more patients. Keywords alcohol dependence, treatment, abstinence, reduced drinking, pharmacotherapy

SOCIO DEMOGRAPHIC FACTORS FOR COMORBID DEPRESSION AMONG ALCOHOL DEPENDENCE PATIENT: A CROSS-SECTIONAL DESCRIPTIVE STUDY.

Despite of high prevalence of depression in alcohol dependent individual, the nature of relationship between depression and alcohol dependence has been difficult to define. Present study investigates the relationship between socio demographic and alcohol related variables with the diagnosis of depression It is a cross-sectional descriptive study with a sample of 50 individuals diagnosed to have alcohol dependence syndrome that consented and fulfilled inclusion and exclusion criteria. MINI-6 was administered for dividing the sample into depressed (n=11, 22%) and non depressed (n=39, 78%) groups. There were only few differences among the two groups on socio-demographic and alcohol related variables. Keywords: Alcohol Dependence, Depression, Co-morbidity, Socio-demographic factors.

RELATIONSHIP OF ALCOHOL AND TOBACCO WITH AVN OF FEMORAL HEAD IN ADULT INDIAN POPULATION

Background: Avascular necrosis (AVN) or osteonecrosis is the death of bone tissues due to decreased blood flow of femoral head, it is a major orthopaedic disease with many risk factors including the chronic alcohol and tobacco consumption. Aims and objectives: To study the relationship of alcohol and tobacco with AVN of femoral head in adult population. Materials and Methods: This study included 72 patients of AVN of femoral head (ONFH) who attending our hospital between Sept 2018 to Sept 2020. History of alcoholism and tobacco consumption, detailed information of the amount and duration of smoking and alcohol intake was recorded. Results: Majority of the AVN patients were working age groups males (72%) and 28% were females. Out of 72 patient 55% had history of alcohol consumption and 60% were smokers which indicates a positive correlation of cellular toxicity with AVN of femoral head. Conclusion: Present study conclude that the alcohol ingestion and tobacco smoking are the major cause of cellular toxicity and AVN of femoral heads. Keywords: alcohol drinking, femur head necrosis, smoking