Dispensary Treatment of Mental Diseases. (Amer. Journ. Insanity, July, 1901.) Channing, W.

1902 ◽  
Vol 48 (200) ◽  
pp. 187-187
Author(s):  
Harrington Sainsbury

Dr. Channing pleads with much force for the wider establishment of out-patient departments for the treatment of mental affections in connection with hospitals and dispensaries. Such departments, besides giving treatment and instruction (a very important part of their work), would serve as a “repository for the troublesome, a clearing house for doubtful cases, and a bureau of information in regard to the necessary machinery to be made use of in committing or otherwise disposing of patients.” Those who have had charge of our overcrowded out-patient rooms will appreciate to the full the need which Dr. Channing points out, for it is absolutely impossible under present conditions to give the mental cases which now and again present themselves as out-patients the attention they require. As it is these sufferers have to content themselves with a dose of mistura alba or calomel, or perhaps a dose of bromide and some hasty words of reassurance, and then the “next patient.” Perhaps the greatest service which these mental departments promise is in connection with defective children, some of whom “furnish a portion of the dullards in the schools, who are such an injury to the advance of the average pupils. Others become tramps or criminals. The girls often become the mothers of illegitimate children, and so spread the circle of degeneration and defect wider and wider.” Dr. Channing accentuates the importance of the last-mentioned work, and in order to utilise more effectually the proposed department he systematises in tabular form the investigation of the defective child.

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


1942 ◽  
Vol 37 (2) ◽  
pp. 291-291
Author(s):  
George Gardner
Keyword(s):  

1913 ◽  
Vol 10 (6) ◽  
pp. 245-246
Author(s):  
No authorship indicated

2019 ◽  
Vol 5 (1) ◽  
pp. 15-22
Author(s):  
Ardian Thresnantia Atmaja

The key objectives of this paper is to propose a design implementation of blockchain based on smart contract which have potential to change international mobile roaming business model by eliminating third-party data clearing house (DCH). The analysis method used comparative analysis between current situation and target architecture of international mobile roaming business that commonly used by TOGAF Architecture Development Method. The purposed design of implementation has validated the business value by using Total Cost of Ownership (TCO) calculation. This paper applies the TOGAF approach in order to address architecture gap to evaluate by the enhancement capability that required from these three fundamental aspect which are Business, Technology and Information. With the blockchain smart contract solution able to eliminate the intermediaries Data Clearing House system, which impacted to the business model of international mobile roaming with no more intermediaries fee for call data record (CDR) processing and open up for online billing and settlement among parties. In conclusion the business value of blockchain implementation in the international mobile roaming has been measured using TCO comparison between current situation and target architecture that impacted cost reduction of operational platform is 19%. With this information and understanding the blockchain technology has significant benefit in the international mobile roaming business.


2017 ◽  
Vol 28 (1-2) ◽  
pp. 28-35 ◽  
Author(s):  
B. A. Baranovski

Nowadays, bioecological characteristics of species are the basis for flora and vegetation studying on the different levels. Bioecological characteristics of species is required in process of flora studying on the different levels such as biotopes or phytocenoses, floras of particular areas (floras of ecologically homogeneous habitats), and floras of certain territories. Ramensky scale is the one of first detailed ecological scales on plant species ordination in relation to various environmental factors; it developed in 1938 (Ramensky, 1971). A little later (1941), Pogrebnyak’s scale of forest stands was proposed. Ellenberg’s system developed in 1950 (Ellenberg, 1979) and Tsyganov’s system (Tsyganov, 1975) are best known as the systems of ecological scales on vascular plant species; these systems represent of habitat detection by ecotopic ecomorphs of plant species (phytoindication). Basically, the system proposed by Alexander Lyutsianovich Belgard was the one of first system of plant species that identiified ectomorphs in relation to environmental factors. As early as 1950, Belgard developed the tabulated system of ecomorphs using the Latin ecomorphs abbreviation; he also used the terminology proposed in the late 19th century by Dekandol (1956) and Warming (1903), as well as terminology of other authors. The article analyzes the features of Belgard’s system of ecomorphs on vascular plants. It has certain significance and advantages over other systems of ecomorphs. The use of abbreviated Latin names of ecomorphs in tabular form enables the use shortened form of ones. In the working scheme of Belgard’s system of ecomorphs relation of species to environmental factors are represented in the abbreviated Latin alphabetic version (Belgard, 1950). Combined into table, the ecomorphic analysis of plant species within association (ecological certification of species), biotope or area site (water area) gives an explicit pattern on ecological structure of flora within surveyed community, biotope or landscape, and on environmental conditions. Development and application by Belgrard the cenomorphs as «species’ adaptation to phytocenosis as a whole» were completely new in the development of systems of ecomorphs and, in this connection, different coenomorphs were distinguished. Like any concept, the system of ecomorphs by Belgard has the possibility and necessity to be developed and added. Long-time researches and analysis of literature sources allow to propose a new coenomorph in the context of Belgard’s system of ecomorphs development: silvomargoant (species of forest margin, from the Latin words margo – edge, boundary (Dvoretsky, 1976), margo – margin, ad margins silvarum – along the deciduous forest margins). As an example of ecomorphic characterization of species according to the system of ecomorphs by Belgard (when the abbreviated Latin ecomorph names are used in tabular form and the proposed cenomorph is used), it was given the part of the table on vascular plants ecomorphs in the National Nature Park «Orelsky» (Baranovsky et al). The Belgard’s system of ecomorphs is particularly convenient and can be successfully applied to data processing in the ecological analysis of the flora on wide areas with significant species richness, and the proposed ecomorph will be another necessary element in the Belgard’s system of ecomorphs. 


Author(s):  
Burbaeva G.Sh. ◽  
Androsova L.V. ◽  
Vorobyeva E.A. ◽  
Savushkina O.K.

The aim of the study was to evaluate the rate of polymerization of tubulin into microtubules and determine the level of colchicine binding (colchicine-binding activity of tubulin) in the prefrontal cortex in schizophrenia, vascular dementia (VD) and control. Colchicine-binding activity of tubulin was determined by Sherlinе in tubulin-enriched extracts of proteins from the samples. Measurement of light scattering during the polymerization of the tubulin was carried out using the nephelometric method at a wavelength of 450-550 nm. There was a significant decrease in colchicine-binding activity and the rate of tubulin polymerization in the prefrontal cortex in both diseases, and in VD to a greater extent than in schizophrenia. The obtained results suggest that not only in Alzheimer's disease, but also in other mental diseases such as schizophrenia and VD, there is a decrease in the level of tubulin in the prefrontal cortex of the brain, although to a lesser extent than in Alzheimer's disease, and consequently the amount of microtubules.


2017 ◽  
Vol 19 (2) ◽  
pp. 131-139
Author(s):  
Kukuh Probo Sukmawati ◽  
Setyowati Setyowati ◽  
Th Ninuk Sri Hartini

  Background: Using of herbs and spices greatly affect the taste of foods, although the ingredients used are the same, different formulations of herbs will produce different flavors. Standardized seasonings are needed to produce a relatively similar food taste. Objective: The research aims to determine the use of herbs in animal and plant proteins. Method: This research was an observational research with cross sectional approach at PanembahanSenopati Hospital Bantul. The objects of this research were standardized seasonings inanimal and plant proteinsin the menu cycle of 10 days in Juny 2015. The data were analyzed descriptively and presented in tabular form and textural. Result: Standardized Seasonings in animal protein were B for satay and C for semur. Standardized seasonings in plant protein were B for bali, terik, rujak and D for bacem. The percentage of the use of seasoning than standardized seasoning for satay (148,7%), bali (130,3%), rujak(372%),for semur, terik and bacem the conformity are not not known because the standardized seasonings unwritten. The conformity of ingredient herbskind for satay (66,7%), semur (100%), bali (54,5%), rujak (50%), bacem (100%) and terik (100%). Conclusion:The conformity of herbs weight foranimal protein (124,3%) and plant protein (175,5%). The conformity of ingredient herbskind for animal protein (83,3%) and plant protein (76,1%). Standardized seasonings used were B, C and D.   Keywords: standardized seasonings, animal protein, plant protein


2020 ◽  
Vol 26 ◽  
Author(s):  
Miquel Martorell ◽  
Xavier Lucas ◽  
Pedro Alarcón-Zapata ◽  
Xavier Capó ◽  
Maria Magdalena Quetglas-Llabrés ◽  
...  

: Mental disorders comprise diverse human pathologies including depression, bipolar affective disorder, schizophrenia, and dementia that affect millions of people around the world. The causes of mental disorders are unclear but growing evidence suggests that oxidative stress and the purine/adenosine system play a key role in their development and progression. Xanthine oxidase (XO) is a flavoprotein enzyme essential for the catalysis of the oxidative hydroxylation of purines -hypoxanthine and xanthine- to generate uric acid. As a consequence of the oxidative reaction of XO, reactive oxygen species (ROS) such as superoxide and hydrogen peroxide are produced and, further, contribute to the pathogenesis of mental disorders. Altered XO activity has been associated with free radical-mediated neurotoxicity inducing cell damage and inflammation. Diverse studies reported a direct association between an increased activity of XO and diverse mental diseases including depression or schizophrenia. Small-molecule inhibitors, such as the well-known allopurinol, and dietary flavonoids, can modulate the XO activity and subsequent ROS production. In the present work, we review the available literature on XO inhibition by small molecules and their potential therapeutic application in mental disorders. In addition, we discuss the chemistry and molecular mechanism of XO inhibitors, as well as the use of structure-based and computational methods to design specific inhibitors with the capability of modulating XO activity.


2019 ◽  
Vol 6 (03) ◽  
Author(s):  
MANIBHUSHAN MANIBHUSHAN ◽  
AKRAM AHMED

The main aim of this study is to apply geographic information system (GIS) and data mining techniques to get the attribute data in a spatial and tabular form related to district wise availability of standing water bodies in their area and number of Bihar state. An analysis has been done on available spatial data and maps to get non-spatial/ tabular data, which are in a more easily understandable form. Data extracted district-wise related to area and number of standing water bodies according to their size of Bihar state. Study shows that the number and area of standing water bodies in Madhubani, East Champaran and Patna districts are 2185, 1753, 350 and 2355.42, 6752.36 and 8429.68 ham respectively. In this way, number and area of standing water bodies of other districts of Bihar are also extracted from geodatabases and digitized maps. This type of information is more useful than the spatial data because a common person is able to understand these tabular data and they can use this data for their own purposes. These data can be utilized by scientific personnel as well as farmers and that will be used in agriculture for better utilization of water resources to enhance agricultural productivity and income of farmers of Bihar state.


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