Use of the SFMA as a measure of overall functionality in patients undergoing hematopoietic stem cell transplantation (HSCT).

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 7119-7119
Author(s):  
Charlotte Shatten ◽  
William Allen Wood ◽  
Robert Butler ◽  
Claudio Battaglini
Keyword(s):  
Movement Patterns ◽  
Composite Score ◽  
Systematic Evaluation ◽  
Functional Impairments ◽  
Hematopoietic Stem ◽  
Movement Assessment ◽  
The Mean ◽  
High Level ◽  
Fundamental Movement Patterns ◽  
Deep Squat

7119 Background: The 6 minute walk test (6MW) has been used in research as a measure of overall functionality and has been related to prognosis and quality of life (QOL) in cancer patients. For some clinics, the use of other functional tests may be a timely and space saving option. The selective functional movement assessment (SFMA) is a short, systematic evaluation of 7 fundamental movement patterns which can be conducted in patient rooms. The SFMA can make clinicians aware of deficient, painful movement patterns that may indicate impairment and motor control deficits. The SFMA may help identify functional impairments for pre- and peri-transplant interventions in patients undergoing HSCT. Methods: Patients were assessed prior to HSCT. A composite score (range: 19-38) was given to patients based SFMA performance. A lower score represented improved movement profiles. 6MW was tested by standardized protocol on an established route. Pearson correlations were calculated to evaluate the relationship between 6MW and SFMA. Results: We evaluated 32 patients (10 autologous, 11 myeloablative allogeneic, 11 reduced intensity allogeneic). One patient was unable to complete all portions of the SFMA due to physical limitations; all patients completed the 6MW. The mean SFMA composite score was 24.9± 3. ≥50% of patients exhibited deficient movement patterns during forward flexion and deep squat. Other patterns that showed a high level of deficiency (> 30% of all patients) were back extension, single leg stance, shoulder mobility, and cervical rotation. The mean 6MW was 477± 94 m. There was a moderate negative correlation between 6MW and SFMA composite score (r =-0.46, p<0.001), implying that a shorter 6MW was associated with more deficient movements. Conclusions: The SFMA could be useful for quantifying overall functionality in settings where the 6MW is not ideal. The SFMA may also be useful for identification of functional issues that may be addressed before or during HSCT by interventions to limit disability and maintain QOL. Further research should evaluate the SFMA results pre to post transplant to assess changes in fundamental movement deficits. The use of the SFMA’s prognostic ability should also be evaluated.

scholarly journals Evaluación de los patrones de movimiento fundamentales en niños: comparación de género en escolares de Educación Primaria (Assessment of fundamental movement patterns in children: a gender comparison on Primary School students)

Retos ◽  
2018 ◽  
pp. 282-286
Author(s):  
Miguel García-Jaén ◽  
Sergio Sellés-Pérez ◽  
Juan Manuel Cortell-Tormo ◽  
Alberto Férriz-Valero ◽  
Roberto Cejuela
Keyword(s):  
Movement Patterns ◽  
Composite Score ◽  
School Students ◽  
Functional Movement ◽  
Increased Risk ◽  
Fundamental Movement Patterns ◽  
Composite Scores ◽  
Deep Squat ◽  
Educación Primaria ◽  
Better Than

El propósito del estudio fue valorar los patrones de movimiento fundamentales en niños y niñas de ocho y nueve años mediante el test Functional Movement ScreenTM(FMS), y establecer una comparación de género entre escolares de Educación Primaria. Para ello, 40 estudiantes de primaria (20 niñas y 20 niños) participaron en el estudio. La ejecución de cada participante se grabó digitalmente durante las clases de Educación Física en el colegio, y posteriormente fue analizada conjuntamente por dos evaluadores expertos en el uso del FMS. Finalmente, se procedió al análisis estadístico de los datos. Los resultados obtenidos mostraron que las niñas obtuvieron puntuaciones más altas en la suma de las siete pruebas, en comparación con los niños (15.3 ± 1.999 vs. 13.75 ± 1.970, p = .017). Particularmente, las niñas puntuaron significativamente mejor que los niños en el test de sentadilla profunda (2.3 ± .657 vs. 2.75 ± .444; p = .015) y en el test de estocada en línea (1.8 ± .834 vs. 2.75 ± .444, p = .000). En conclusión, las niñas obtuvieron una puntuación total en el test FMS superior a los niños, puntuando significativamente mejor que los niños en el test de sentadilla profunda y en el test de estocada en línea. Además, la mayoría de las niñas puntuaron por encima de 14 puntos, mientras que la mayoría de los niños puntuaron igual o por debajo de 14 puntos, lo cual podría indicar una menor competencia motriz y un riesgo incrementado de lesión en los niños. The aim of this study was to evaluate the fundamental movement patterns in eight and nine-year-old children, using the Functional Movement ScreenTMtest (FMS) and analyzing gender differences in FMS scores among Primary Education students. 40 children, 20 girls and 20 boys, participated in this study. The performance of each participant on the FMS was digitally recorded during the Physical Education classes at school. After that, collected data were analyzed by two expert evaluators in FMS. Finally, a statistical data analysis was developed. The obtained results showed that females had higher total composite scores in the seven FMS test compared with males (15.3 ± 1.999 vs. 13.75 ± 1.970, p = .017). Particularly, females scored significantly better than males in the deep squat test (2.3 ± .657 vs. 2.75 ± .444; p = .015) and in the in-line lunge test (1.8 ± .834 vs. 2.75 ± .444,p = .000). In conclusion, females obtained higher total composite score than the males in the FMS test, scoring significantly better than males in deep squat test and in the in-line lunge test. In addition, the majority of the females scored above 14 points, while most of the males scored 14 or less points on the FMS total composite score, which could be an indicative of less motor skills and also an increased risk of injury in males. 

scholarly journals EFFECT OF “FIFA 11+” ON THE PATTERN OF FUNDAMENTAL MOVEMENTS IN UNDER-14 SOCCER PLAYERS

2017 ◽  
Vol 23 (6) ◽  
pp. 465-468 ◽  
Author(s):  
Gerald Baeza ◽  
Gustavo Paredes ◽  
Pablo Vega ◽  
Manuel Monrroy ◽  
Rubén Gajardo-Burgos
Keyword(s):  
Movement Patterns ◽  
Neuromuscular Control ◽  
Soccer Players ◽  
Control Group ◽  
Functional Movement Screen ◽  
Post Intervention ◽  
Functional Movement ◽  
Quasi Experimental ◽  
Fundamental Movement Patterns ◽  
Deep Squat

ABSTRACT Introduction: Increasing youth participation in soccer has several benefits, but it also brings risks of injury. The use of neuromuscular techniques is effective in preventing injuries, especially in periods of growth as occurs in puberty, which coincides with the development of fundamental basic movements. Therefore, it is important to implement and evaluate prevention programs that focus on neuromuscular control during this stage. Objective: To determine the effect of the FIFA 11+ over a six-week training period in order to quickly improve fundamental movement patterns in under-14 soccer players. Method: A quasi-experimental study that evaluated the fundamental movement patterns through the Functional Movement Screen (FMS) in 22 athletes who were divided into a control group (CG; N=11) and an experimental group (EG; N=11), submitted to the program FIFA 11+ for six weeks. The SPSS 20.0 program was used to analyze the data. Results: Statistically significant improvements were found in the in-line lunge (IL) and in the post-intervention FMS total scores in EG, as well as intergroup improvements when testing the deep squat (DS) in the EG, but not in both groups. Conclusions: The six week FIFA 11+ program did not produce significant improvements in players’ fundamental movements.

DFT Benchmark Study of the O--O Bond Dissociation Energy in Peroxides Validated with High-Level Ab-Initio Calculations

2019 ◽  
Author(s):  
Danilo Carmona ◽  
Pablo Jaque ◽  
Esteban Vöhringer-Martinez
Keyword(s):  
Reference Value ◽  
Basis Set ◽  
Basis Sets ◽  
Mean Deviation ◽  
Bond Dissociation ◽  
Dissociation Energies ◽  
The Mean ◽  
Experimental Values ◽  
High Level ◽  
Almost All

<div><div><div><p>Peroxides play a central role in many chemical and biological pro- cesses such as the Fenton reaction. The relevance of these compounds lies in the low stability of the O–O bond which upon dissociation results in radical species able to initiate various chemical or biological processes. In this work, a set of 64 DFT functional-basis set combinations has been validated in terms of their capability to describe bond dissociation energies (BDE) for the O–O bond in a database of 14 ROOH peroxides for which experimental values ofBDE are available. Moreover, the electronic contributions to the BDE were obtained for four of the peroxides and the anion H2O2− at the CBS limit at CCSD(T) level with Dunning’s basis sets up to triple–ζ quality provid- ing a reference value for the hydrogen peroxide anion as a model. Almost all the functionals considered here yielded mean absolute deviations around 5.0 kcal mol−1. The smallest values were observed for the ωB97 family and the Minnesota M11 functional with a marked basis set dependence. Despite the mean deviation, order relations among BDE experimental values of peroxides were also considered. The ωB97 family was able to reproduce the relations correctly whereas other functionals presented a marked dependence on the chemical nature of the R group. Interestingly, M11 functional did not show a very good agreement with the established order despite its good performance in the mean error. The obtained results support the use of similar validation strategies for proper prediction of BDE or other molecular properties by DF Tmethods in subsequent related studies.</p></div></div></div>

The way of value of Correlation of genomic DNA microsatellite loci and live weight of Chukchi reindeer

2020 ◽  
pp. 27-32
Author(s):  
V. Dodokhov ◽  
N. Pavlova ◽  
T. Rumyantseva ◽  
L. Kalashnikova
Keyword(s):  
Microsatellite Markers ◽  
Agricultural Production ◽  
Live Weight ◽  
Biodiversity Loss ◽  
Tribal Community ◽  
High Germination ◽  
Wide Range ◽  
The Mean ◽  
High Level ◽  
Dna Microsatellite

The article presents the genetic characteristic of the Chukchi reindeer breed. The object of the study was of the Chukchi reindeer. In recent years, the number of reindeer of the Chukchi breed has declined sharply. Reduced reindeer numbers could lead to biodiversity loss. The Chukchi breed of deer has good meat qualities, has high germination viability and is adapted in adverse tundra conditions of Yakutia. Herding of the Chukchi breed of deer in Yakutia are engaged only in the Nizhnekolymsky district. There are four generic communities and the largest of which is the agricultural production cooperative of nomadic tribal community «Turvaurgin», which was chosen to assess the genetic processes of breed using microsatellite markers: Rt6, BMS1788, Rt 30, Rt1, Rt9, FCB193, Rt7, BMS745, C 143, Rt24, OheQ, C217, C32, NVHRT16, T40, C276. It was found that microsatellite markers have a wide range of alleles and generally have a high informative value for identifying of genetic differences between animals and groups of animal. The number of identified alleles is one of the indicators of the genetic diversity of the population. The total number of detected alleles was 127. The Chukchi breed of deer is characterized by a high level of heterozygosity, and the random crossing system prevails over inbreeding in the population. On average, there were 7.9 alleles (Na) per locus, and the mean number of effective alleles (Ne) was 4.1. The index of fixation averaged 0.001. The polymorphism index (PIC) ranged from 0.217 to 0.946, with an average of 0.695.

A comparison of functional movement patterns between female low back pain developers and non-pain developers

Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Fatemeh Khoshroo ◽  
Foad Seidi ◽  
Reza Rajabi ◽  
Abbey Thomas
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Muscle Activation ◽  
Statistical Significance ◽  
Movement Patterns ◽  
Composite Score ◽  
Quality Data ◽  
Low Back ◽  
Functional Movement ◽  
Prolonged Standing

BACKGROUND: Distinctive features of low back pain-developers (LBPDs) as pre-clinical low back pain (LBP) population have been evidenced in three areas of alignment, muscle activation, and movement patterns. To clarify whether the reported altered functional movement patterns in chronic LBP patients result from or result in LBP disorders, LBPDs’ functional movement patterns should be investigated. OBJECTIVES: This study aimed to compare female LBPDs’ functional movement patterns with non-pain developers’ (NPDs). METHODS: Sixty female LBPDs and NPDs were recruited based on the research requirements. The Functional Movement Screen (FMS) was used to investigate movement quality. Data were compared between groups via Mann-Whitney U tests and correlation analyses examined association between pain intensity and onset during prolonged standing and the FMS score. Receiver Operating Characteristic Curves and Chi Squares were conducted to find the best cutoff points. An alpha level of p≤0.05 was used to establish statistical significance. RESULTS: LBPDs scored significantly lower, or rather worse than NPDs in the FMS composite score (12.06±1.33 vs. 16.43±1.59, U = 3, P <  0.001). Moreover, the optimal cutoff scores of≤14 on the FMS, 2 on the push-up, and 1 on the deep squat discriminated between female LBPDs and NPDs. The FMS composite score was correlated negatively with LBP intensity (r (60) = –0.724, p <  0.001) and positively with LBP onset (r (60) = 0.277, p = 0.032) during prolonged standing. Finally, the results indicated that female LBPDs presented with at least one bilateral asymmetry on the FMS had 10 times (95%CI, 2.941–34.008) and with at least two bilateral asymmetries on the FMS had 15.5 times (95%CI, 3.814–63.359) higher odds of developing LBP during prolonged standing than NPDs. CONCLUSIONS: Female LBPDs, who are at higher risk for developing LBP in the future, have significantly lower quality of functional movement patterns compared to NPDs. Moreover, the FMS appears to show promise for predicting individuals who are at risk for LBP development during prolonged standing.

scholarly journals AB0189 LIPOPROTEIN ABNORMALITIES IN RHEUMATOID ARTHRITIS PATIENTS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1119.1-1119
Author(s):  
L. Nacef ◽  
Y. Besbes ◽  
Y. Mabrouk ◽  
H. Ferjani ◽  
K. Maatallah ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Demographic Data ◽  
Calcium Score ◽  
Healthy Person ◽  
Mean Value ◽  
Immunological Parameters ◽  
American College Of Rheumatology ◽  
Patient Consent ◽  
The Mean ◽  
High Level

Background:The lipid paradox is termed the decreased cholesterol level in rheumatoid arthritis (RA). Nevertheless, the apolipoprotein levels are usually higher than a healthy person and are predictors of cardiovascular events.Objectives:We aimed to describe lipid abnormalities in RA patients and to look for predictor factors of these changes.Methods:The prospective study was carried out on patients with RA who met the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria. These patients were followed in the rheumatology department of the Kassab Institute.We collected the socio-demographic data, biological and immunological parameters.The lipid assessment included: a measurement of total cholesterol (TC), HDL, LDL, and triglycerides (TG). Lipoproteins APOA1 and APOB were measured. All data were collected after patient consent.Results:Of the 47 patients recruited, 78.7% were female. The mean age was 52.5 ±11.06 [32-76]. The average RA progressed from 86.25 ±63 months [5-288] and was erosive in 81.6% of cases. The rheumatoid factor (RF) was positive in 57.8% of patients, and citrullinated antipeptide antibodies (ACPA) were present in 62.2%. Eight patients had a previous CV history.Mean TC was 4.42 ±1.3 [1.2-7.58], mean HDL was 1.38 ±0.73 [0.18-4.10], mean LDL was 2.55 ±1.16 [0.24-5.54]. The mean TG value was 1.28 ±0.6 [0.24-5.54]. TC elevation was found in 9.1% of cases, HDL in 21.3% of cases, LDL in 5.5% of cases, and TG in 16.4% of cases. Mean APOB/APOA1 ratio was 0.67 ±0.18 [0,46-1,11]. LDL elevation was associated to a high DAS28 (p=0.06, r=0.512). APOA1 was associated to a low DAS28 (p=0.04, r=-0.642).The mean value of APO A1 was 1.36 ±0.21 [0.84-1.81], that of APOB was 0.90 ±0.22 [0.58-1.40]. APOA1 values were lower in patients with high-level LDL (p=0.767). The APOB value was associated with lipid disturbance without significant correlation (p=0.291).Conclusion:Lipid test abnormalities can be found in RA patients outside of any known CV risk factors. APOA1 seems to have a protective effect. Screening and treatment of these abnormalities can prevent CV risk.References:[1]Miguel Bernardes and al. Coronary artery calcium score in female rheumatoid arthritis patients: Associations with apolipoproteins and disease biomarkers. Int J Rheum Dis. 2019;00:1–16.[2]Anna So dergren and al. Biomarkers associated with cardiovascular disease in patients with early rheumatoid arthritis. PLOS ONE. August 5, 2019.Disclosure of Interests:None declared

scholarly journals Rates of Cognitive and Functional Impairments in Older Adults Residing in a Continuing Care Senior Housing Community

2021 ◽  
pp. 1-12
Author(s):  
Ryan Van Patten ◽  
Zanjbeel Mahmood ◽  
Tanya T. Nguyen ◽  
Jacqueline E. Maye ◽  
Ho-Cheol Kim ◽  
...  
Keyword(s):  
Older Adults ◽  
Functional Capacity ◽  
Independent Living ◽  
Visual Learning ◽  
Cognitive Test ◽  
Continuing Care ◽  
Cognitive Screening ◽  
Functional Impairments ◽  
Senior Housing ◽  
The Mean

Abstract Objective: The current cross-sectional study examined cognition and performance-based functional abilities in a continuing care senior housing community (CCSHC) that is comparable to other CCSHCs in the US with respect to residents’ demographic characteristics. Method: Participants were 110 older adult residents of the independent living unit. We assessed sociodemographics, mental health, neurocognitive functioning, and functional capacity. Results: Compared to normative samples, participants performed at or above expectations in terms of premorbid functioning, attention span and working memory, processing speed, timed set-shifting, inhibitory control, and confrontation naming. They performed below expectation in verbal fluency and verbal and visual learning and memory, with impairment rates [31.4% (>1 SD below the mean) and 18.49% (>1.5 SD below the mean)] well above the general population (16% and 7%, respectively). Within the cognitive test battery, two tests of delayed memory were most predictive of a global deficit score. Most cognitive test scores correlated with performance-based functional capacity. Conclusions: Overall, results suggest that a subset of older adults in the independent living sector of CCSHCs are cognitively and functionally impaired and are at risk for future dementia. Results also argue for the inclusion of memory tests in abbreviated screening batteries in this population. We suggest that CCSHCs implement regular cognitive screening procedures to identify and triage those older adults who could benefit from interventions and, potentially, a transition to a higher level of care.

scholarly journals The Problems and Needs of Patients Diagnosed with Cancer and Their Caregivers

2020 ◽  
Vol 18 (1) ◽  
pp. 87
Author(s):  
Anna Lewandowska ◽  
Grzegorz Rudzki ◽  
Tomasz Lewandowski ◽  
Sławomir Rudzki
Keyword(s):  
Cancer Patients ◽  
Medical Information ◽  
Unmet Needs ◽  
Public Healthcare ◽  
Literature Analysis ◽  
The Public ◽  
The Mean ◽  
High Level ◽  
Patients Experience

(1) Background: As the literature analysis shows, cancer patients experience a variety of different needs. Each patient reacts differently to the hardships of the illness. Assessment of needs allows providing more effective support, relevant to every person’s individual experience, and is necessary for setting priorities for resource allocation, for planning and conducting holistic care, i.e., care designed to improve a patient’s quality of life in a significant way. (2) Patients and Methods: A population survey was conducted between 2018 and 2020. Cancer patients, as well as their caregivers, received an invitation to take part in the research, so their problems and needs could be assessed. (3) Results: The study involved 800 patients, 78% women and 22% men. 66% of the subjects were village residents, while 34%—city residents. The mean age of patients was 62 years, SD = 11.8. The patients received proper treatment within the public healthcare. The surveyed group of caregivers was 88% women and 12% men, 36% village residents and 64% city residents. Subjects were averagely 57 years old, SD 7.8. At the time of diagnosis, the subjects most often felt anxiety, despair, depression, feelings of helplessness (46%, 95% CI: 40–48). During illness and treatment, the subjects most often felt fatigued (79%, 95% CI: 70–80). Analysis of needs showed that 93% (95% CI: 89–97) of patients experienced a certain level of need for help in one or more aspects. (4) Conclusions: Patients diagnosed with cancer have a high level of unmet needs, especially in terms of psychological support and medical information. Their caregivers also experience needs and concerns regarding the disease. Caregivers should be made aware of the health consequences of cancer and consider appropriate supportive care for their loved ones.

scholarly journals The fate of Si and Fe while nuclear glass alters with steel and clay

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
C. Carriere ◽  
P. Dillmann ◽  
S. Gin ◽  
D. Neff ◽  
L. Gentaz ◽  
...  
Keyword(s):  
Dissolution Rate ◽  
Protective Layer ◽  
Glass Dissolution ◽  
A Value ◽  
Waste Forms ◽  
Controlling Mechanism ◽  
Geological Repository ◽  
The Mean ◽  
High Level ◽  
Initial Dissolution Rate

AbstractThe French concept developed to dispose high-level radioactive waste in geological repository relies on glassy waste forms, isolated from the claystone host rock by steel containers. Understanding interactions between glass and surrounding materials is key for assessing the performance of a such system. Here, isotopically tagged SON68 glass, steel and claystone were studied through an integrated mockup conducted at 50 °C for 2.5 years. Post-mortem analyses were performed from nanometric to millimetric scales using TEM, STXM, ToF-SIMS and SEM techniques. The glass alteration layer consisted of a crystallized Fe-rich smectite mineral, close to nontronite, supporting a dissolution/reprecipitation controlling mechanism for glass alteration. The mean glass dissolution rate ranged between 1.6 × 10−2 g m−2 d−1 to 3.0 × 10−2 g m−2 d−1, a value only 3–5 times lower than the initial dissolution rate. Thermodynamic calculations highlighted a competition between nontronite and protective gel, explaining why in the present conditions the formation of a protective layer is prevented.

scholarly journals 24-Hour Measurement of Gastric pH in Rural South Africa

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Alastair M. Sammon ◽  
Eugene J. Ndebia ◽  
Ekambaram Umapathy ◽  
Jehu E. Iputo
Keyword(s):  
South Africa ◽  
Ambulatory Monitoring ◽  
Duodenogastric Reflux ◽  
Lower Oesophageal Sphincter ◽  
Gastric Ph ◽  
Night Time ◽  
High Incidence ◽  
The Mean ◽  
H Pylori ◽  
High Level

Background. Previous studies have established norms of 24-hour gastric pH profiles for western countries. This study was designed to establish the pattern for a rural African population with a high incidence of oesophageal cancer.Methods. After lower oesophageal manometry a probe was placed 10 cm distal to the lower oesophageal sphincter. We carried out 24-hour ambulatory monitoring of gastric pH on 59 healthy subjects. This was satisfactorily completed on 26 female and 18 male (age 21–64, median 35) subjects in the Transkei region of South Africa.Results. The mean 24 hour gastric pH was 2.84 and the mean night-time pH was 3.7. 40 volunteers recorded a night-time pH reaching over 4. 33 volunteers recorded a night-time pH over 7. Night-time alkalinisation was present for 136.4 minutes (25th centile 22.8, 75th centile 208.1) at pH4 or over, and 79.3 (2.5, 122.7) minutes at pH7 or over. Episodes of rapid alkaline rise were 17 (10, 47). 21.1% of these occurred while supine. 35 of 36 tested subjects were positive forH. pyloriIgG.Conclusion. Gastric alkalinisation is common in Transkei, at a higher pH than that reported in other studies, and is sustained longer. Nighttime alkalinisation is frequent. This suggests a high level of duodenogastric reflux.

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