Employment concerns experienced by ovarian cancer patients and caregivers.

69 Background: Our aim was to obtain patient input on the impact of cancer treatment on employment. Methods: We recruited patients with ovarian cancer receiving systemic therapy who screened positive for financial distress using Comprehensive Score for Financial Toxicity <26. Participants completed a 45-minute interview with 2 interviewers on their costs of care, including employment concerns. Interviews were recorded, transcribed, and coded by 3 analysts using inductive thematic analysis. Results: Of 22 participants, 86% were <65 years old and 28% were on curative intent treatment. There were 18 with currently evaluable interviews. Themes are shown in the table. Conclusions: Cancer care has a negative impact on patient and caregiver work productivity, income, and employer benefits. Incorporating resources to navigate workplace factors, such as Family Medical Leave Act benefits and negotiating accommodations with an employer, could improve care delivery. [Table: see text]

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A Cross-Sectional Survey Exploring the Impact of the COVID-19 Pandemic on the Cancer Care of Adolescents and Young Adults

Current Oncology ◽

10.3390/curroncol28040278 ◽

2021 ◽

Vol 28 (4) ◽

pp. 3201-3213

Author(s):

Kaitlyn Howden ◽

Camille Glidden ◽

Razvan G. Romanescu ◽

Andrew Hatala ◽

Ian Scott ◽

...

Keyword(s):

Young Adults ◽

Cancer Treatment ◽

Cancer Care ◽

Negative Impact ◽

Positive Impact ◽

Care Delivery ◽

Adolescents And Young Adults ◽

P Value ◽

Cross Sectional Survey ◽

The Impact

We aimed to describe the negative and positive impacts of changes in cancer care delivery due to COVID-19 pandemic for adolescents and young adults (AYAs) in Canada, as well as the correlates of negative impact and their perspectives on optimization of cancer care. We conducted an online, self-administered survey of AYAs with cancer living in Canada between January and February 2021. Multiple logistic regression was used to identify factors associated with a negative impact on cancer care. Of the 805 participants, 173 (21.5%) experienced a negative impact on their cancer care including delays in diagnostic tests (11.9%), cancer treatment (11.4%), and appointments (11.1%). A prior diagnosis of mental or chronic physical health condition, an annual income of <20,000 CAD, ongoing cancer treatment, and province of residence were independently associated with a negative cancer care impact (p-value < 0.05). The majority (n = 767, 95.2%) stated a positive impact of the changes to cancer care delivery, including the implementation of virtual healthcare visits (n = 601, 74.6%). Pandemic-related changes in cancer care delivery have unfavorably and favorably influenced AYAs with cancer. Interventions to support AYAs who are more vulnerable to the adverse effects of the pandemic, and the thoughtful integration of virtual care into cancer care delivery models is essential.

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Residency training amid the COVID-19 pandemic: exploring the impact on mental health and training, a lesson from Iran

BMC Medical Education ◽

10.1186/s12909-021-03029-4 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Ashraf Moini ◽

Khadije Maajani ◽

Ramesh Omranipour ◽

Mohamad-Reza Zafarghandi ◽

Ashraf Aleyasin ◽

...

Keyword(s):

Mental Health ◽

Residency Training ◽

General Surgery ◽

Negative Impact ◽

Care Delivery ◽

Cross Sectional Study ◽

Multiple Choice Questions ◽

Cross Sectional ◽

Questions And Answers ◽

The Impact

Abstract Background COVID-19 has affected the training programs and the clinical schedules of surgical wards in many countries, including Iran. Also, the continuous involvement with COVID-19 patients has caused stress in health care workers; among them, residents are on the frontlines of care delivery. Therefore, we designed a study to assess the mental effects of these circumstances, and the effects on General Surgery and Obstetrics & Gynecology residency training in the busiest surgical departments of our university. Methods Participants of this cross-sectional study were residents of General Surgery and Obstetrics & Gynecology of Tehran University of Medical Sciences, and the conventional sampling method was used. We used a questionnaire consisting of 47 questions (mostly using multiple choice questions and answers on the Likert scale) about personal, familial, and demographic characteristics; training activities, and mental effects of COVID-19. Results The response rate was 63.5%. (127 filled questionnaires). Around 96% of the residents had emotional problems, 85.9% were highly stressed about contracting COVID-19, 81.3% were worried about transferring it to their families; and 78% believed that their residency training had been impaired. Conclusion Overall, our study shows the negative impact of COVID-19 on mental health and the training of residents. We propose that appropriate emotional support and suitable planning for compensation of training deficits is provided for residents.

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FAKTOR DETERMINAN FINANCIAL DISTRESS UNTUK PERUSAHAAN PERTAMBANGAN DI INDONESIA DAN MALAYSIA

Nominal Barometer Riset Akuntansi dan Manajemen ◽

10.21831/nominal.v10i2.35763 ◽

2021 ◽

Vol 10 (2) ◽

pp. 168-187

Author(s):

Arief Bagas Prasetyo ◽

Farida Titik Kristanti

Keyword(s):

Logistic Regression ◽

Financial Distress ◽

Negative Impact ◽

Institutional Ownership ◽

Managerial Ownership ◽

Descriptive Research ◽

Mining Companies ◽

Operating Capacity ◽

Processing Techniques ◽

The Impact

Abstrak: Faktor determinan Financial Distress Untuk Perusahaan Pertambangan Di Indonesia dan Malaysia. Studi ini bermaksud untuk mengetahui dampak likuiditas, leverage, operating capacity, instittutional ownership, managerial ownership, sertakomisaris independen padaFinancial Distress. Penelitian ini memakai penelitian deskriptif. Populasi serta sampel pada studi ialah perseroan sektor pertambangan yang tercatat di BursaEfek Indonesia dan Bursa Malaysia 2014-2018. Studi ini memakai purposive sampling serta diperoleh 12 perseoran di Indonesia dan 22 perseroan di Malaysia. Olah data yang dipakai studi ini memakai logistic regression. Studi menunjukkan pada perseroan pertambangan di Indonesia bahwa operatingcapacity scara parsial mempunyai pengaruh signifikan negatif pada financial distress. Sedangkan liquidity ,leverage, institutional ownership, managerial ownership, dan independent comissioner secara parsial tidak mempunyai pengaruh pada financial distress. Kemudian pada perseroan pertambangan di Malaysia menunjukkan bahwa liquidity, Managerial Ownership, dan Independent Commissioner secara parsial mempunyai pengaruh signifikan negatif pada financial distress. Sedangkan operating capacity,leverage, dan Institutional Ownership secara parsial tidak mempunyai pengaruh pada financial distress.Kata kunci: Liquidity, Leverage, OperatingCapacity, Institutional Ownership, Managerial Ownership, Independent Commissioner, Financial DistressAbstract: Determinants ofFinancial Distressfor Mining Companies in Indonesia and Malaysia. Research intend todetermine the impact ofliquidity, leverage, operatingcapacity, institutional ownership, managerialownership, and independent commissioner onfinancial distress. This research uses descriptive research. Thepopulation and sample are miningsector firm registered onthe IDX and Malaysia Exchange 2014-2018. This study uses purposivesamplingmethod acquired 12 companies in Indonesia and 22 companies in Malaysia. The data processing techniques used logisticregression. Research showed mining companies in Indonesia that their operating capacityhas a negative impact on financial distress. Whereas, liquidity,leverage, institutionalownership, managerialownership, and the independentcommissioner didn’t have affects onfinancial distress. Then the mining companies in Malaysia showed that liquidity, Managerial Ownership, and Independent Commissionerhave a negative impact onfinancial distress. Meanwhile, operating capacity, leverage, and institutional ownership didn’t have affects on financial distress.Keywords: Liquidity, Leverage, OperatingCapacity, Institutional Ownership, Managerial Ownership, Independent Commissioner, Financial Distress

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Well-Being of Caregivers of Patients with Laryngeal Cancer Treated by Radiotherapy

International Archives of Otorhinolaryngology ◽

10.1055/s-0039-3399542 ◽

2020 ◽

Vol 24 (02) ◽

pp. e170-e174

Author(s):

Therese Karlsson ◽

Mia Johansson ◽

Caterina Finizia

Keyword(s):

Laryngeal Cancer ◽

Negative Impact ◽

Early Stage ◽

Depression Scale ◽

Well Being ◽

Hospital Treatment ◽

Curative Intent ◽

Treatment Pathway ◽

Male Caregivers ◽

The Impact

Abstract Introduction Laryngeal cancer is the second most common head and neck cancer, but no study to date reports exclusively on the well-being of the caregivers of patients with laryngeal cancer treated by radiotherapy. Objective The present prospective pilot study aims to describe the impact of the work on the well-being of the caregivers of patients with laryngeal cancer. Methods The caregivers of patients undergoing radiotherapy with curative intent for laryngeal cancer were included in the present study, and they were asked to fill out a specific questionnaire, while the patients filled out the Hospital Anxiety and Depression Scale (HADS) following diagnosis but prior to treatment. Results A total of 50 caregivers were included, 20% of which were male, and 80%, female. In total, 62% (n = 31) of the caregivers were spouses, while the remaining were daughters/sons (n = 11; 22%), siblings (n = 6; 12%), or they were classified as “other” (n = 2; 4%). The female caregivers scored lower (worse) on the depression/worry domain, and this was statistically significant (p = 0.047); they also reported a statistically significant higher negative impact on employment (p = 0.011) compared with the male caregivers. In general, the caregivers of patients with late-stage tumors tended to report lower (worse) scores on all domains (except hospital contact) compared with the caregivers of patients with early-stage tumors. No other differences were observed regarding the patients' age, gender, tumor site or their HADS score. Conclusion The diagnosis and treatment of laryngeal cancer impacts the caregiver's psychological well-being, particularly that of female caregivers. This should be taken into consideration when the patients begin the hospital treatment pathway. However, larger studies are needed to target resources more appropriately.

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Impact of consultant obstetric presence on serious incidents

International Journal of Health Governance ◽

10.1108/ijhg-12-2018-0079 ◽

2019 ◽

Vol 24 (3) ◽

pp. 187-193

Author(s):

Sherif Shawer ◽

Shirley Rowbotham ◽

Alexander Heazell ◽

Teresa Kelly ◽

Sarah Vause

Keyword(s):

Negative Impact ◽

Positive Impact ◽

Care Delivery ◽

A Priori ◽

Improve Patient Care ◽

Positive Influence ◽

Content Type ◽

Uk National Health Service ◽

The Impact ◽

Improve Patient

Purpose Many organisations, including the Royal College of Obstetricians and Gynaecologists, have recommended increasing the number of hours of consultant obstetric presence in UK National Health Service maternity units to improve patient care. St Mary’s Hospital, Manchester implemented 24-7 consultant presence in September 2014. The paper aims to discuss these issues. Design/methodology/approach To assess the impact of 24-7 consultant presence upon women and babies, a retrospective review of all serious clinical intrapartum incidents occurring between September 2011 and September 2017 was carried out by two independent reviewers; disagreements in classification were reviewed by a senior Obstetrician. The impact of consultant presence was classified in a structure agreed a priori. Findings A total of 72 incidents were reviewed. Consultants were directly involved in the care of 75.6 per cent of cases before 24-7 consultant presence compared to 96.8 per cent afterwards. Negative impact due to a lack of consultant presence fell from 22 per cent of the incidents before 24-7 consultant presence to 9.7 per cent after implementation. In contrast, positive impact of consultant presence increased from 14.6 to 32.3 per cent following the introduction of 24-7 consultant presence. Practical implications Introduction of 24-7 consultant presence reduced the negative impact caused by a lack of, or delay in, consultant presence as identified by serious untoward incident (SUI) reviews. Consultant presence was more likely to have a positive influence on care delivery. Originality/value This is the first assessment of the impact of 24-7 consultant presence on the SUIs in obstetrics.

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A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer

Scientific Reports ◽

10.1038/s41598-021-93718-3 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Masato Yoshihara ◽

Ryo Emoto ◽

Kazuhisa Kitami ◽

Shohei Iyoshi ◽

Kaname Uno ◽

...

Keyword(s):

Ovarian Cancer ◽

Large Scale ◽

Negative Impact ◽

Early Stage ◽

Stage Iv ◽

Therapeutic Interventions ◽

Limited Information ◽

Mucinous Histology ◽

Staging Surgery ◽

The Impact

AbstractPositive ascites cytology is a strong prognostic factor in patients with early-stage ovarian cancer (OvCa). However, limited information is currently available on the impact of positive ascites cytology on patient prognoses under each clinical background. We herein investigated the comprehensive impact of positive ascites cytology on patients with epithelial OvCa and the effectiveness of additional therapeutic interventions, including complete staging surgery and chemotherapy. Among 4730 patients with malignant ovarian neoplasms, retrospectively identified in multiple institutions, 1906 with epithelial OvCa were included. In the investigation of its effects on clinical factors using a multivariate analysis, positive ascites cytology correlated with a poor prognosis. Positive ascites cytology had a significantly worse prognosis than those with negative cytology in all subgroups except for patients with stage IV tumors and a mucinous histology. Chemotherapy may be effective in reducing the negative impact of positive ascites cytology on the prognosis of patients in terms of progression-free and overall survivals, while complete staging surgery did not improve the prognosis of patients with positive ascites cytology. Collectively, our findings suggested that positive ascites cytology had a negative impact on the prognosis of patients with epithelial OvCa, but not those with stage IV tumors or a mucinous histology.

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Prognostic Aspects of Positive Ascites Cytology and Effects of Therapeutic Interventions in Epithelial Ovarian Cancer: a Large-scale Multi-institutional Study

10.21203/rs.3.rs-431054/v1 ◽

2021 ◽

Author(s):

Masato Yoshihara ◽

Ryo Emoto ◽

Kazuhisa Kitami ◽

Shohei Iyoshi ◽

Kaname Uno ◽

...

Keyword(s):

Ovarian Cancer ◽

Large Scale ◽

Negative Impact ◽

Early Stage ◽

Stage Iv ◽

Therapeutic Interventions ◽

Limited Information ◽

Mucinous Histology ◽

Staging Surgery ◽

The Impact

Abstract Positive ascites cytology is a strong prognostic factor in patients with early-stage ovarian cancer (OvCa). However, limited information is currently available on the impact of positive ascites cytology on patient prognoses under each clinical background. We herein investigated the comprehensive impact of positive ascites cytology on patients with epithelial OvCa and the effectiveness of additional therapeutic interventions, including complete staging surgery and chemotherapy. Among 4,730 patients with malignant ovarian neoplasms, retrospectively identified in multiple institutions, 1,906 with epithelial OvCa were included. In the investigation of its effects on clinical factors using a multivariate analysis, positive ascitic cytology correlated with a poor prognosis. Positive ascites cytology had a significantly worse prognosis than those with negative cytology in all subgroups except for patients with stage IV tumors and a mucinous histology. Chemotherapy may be effective in reducing the negative impact of positive ascites cytology on the prognosis of patients in terms of progression-free and overall survivals, while complete staging surgery did not improve the prognosis of patients with positive ascites cytology. Collectively, our findings suggested that positive ascites cytology had a negative impact on the prognosis of patients with epithelial OvCa, but not those with stage IV tumors or a mucinous histology.

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Work productivity in the sector of knowledge intensive services in relation to work productivity in the manufacturing industry

Trendy v podnikání ◽

10.24132/jbt.2020.10.4.4_8 ◽

2021 ◽

Vol 10 (4) ◽

pp. 4-8

Author(s):

Jaromír Vrbka ◽

Zuzana Rowland ◽

Lukáš Frýd

Keyword(s):

Manufacturing Industry ◽

Negative Impact ◽

Work Productivity ◽

Value Added ◽

Support Service ◽

Economic Activities ◽

Long Run ◽

Positive Shock ◽

The Impact ◽

Adf Test

The manufacturing industry represents the most important part of gross output in the Czech Republic. In the long run, it is necessary for the Czech industry to be competitive. At the same time, it can be assumed that foreign pressure on the Czech manufacturing industry will at least partially transform into pressure on professional and scientific activities. Science and research thus play a key role. The aim of the article is to analyse the impact of work efficiency in the branch of professional, scientific, technical, administrative and support service activities (i.e. sections M and N of the CZ NACE classification of economic activities) on the manufacturing industry (section C). Productivity is measured as gross value added to the labor. The quarterly data of the Czech Statistical Office for the period 1995-2020 are used for the analysis. Time series are processed using a Census X12 filter; all variables are tested using the ADF test in two variants for the presence of a unit root. The testing of the long-term relationship is conducted by means of the Johansen test. The results show that both productivity delays in sector C and sectors M and N have a statistically significant impact on productivity in sector C. However, a positive productivity shock in sector C has a negative impact on current productivity and, conversely, a positive shock in productivity in branch M + N in t-1 is positively reflected in branch C at time t.

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Impact of COVID-19 on Tuberculosis Case Detection and Treatment Outcomes in Sierra Leone

Tropical Medicine and Infectious Disease ◽

10.3390/tropicalmed6030154 ◽

2021 ◽

Vol 6 (3) ◽

pp. 154

Author(s):

Sulaiman Lakoh ◽

Darlinda F. Jiba ◽

Mamadu Baldeh ◽

Olukemi Adekanmbi ◽

Umu Barrie ◽

...

Keyword(s):

Treatment Outcomes ◽

Sierra Leone ◽

Negative Impact ◽

Care Delivery ◽

Treatment Success ◽

Multivariate Logistic Regression Analysis ◽

Policy Implications ◽

Case Detection ◽

Self Administration ◽

The Impact

The COVID-19 pandemic has adversely affected tuberculosis (TB) care delivery in high burden countries. We therefore conducted a retrospective study to assess the impact of COVID-19 on TB case detection and treatment outcomes at the Chest Clinic at Connaught Hospital in Freetown, Sierra Leone. Overall, 2300 presumptive cases were tested during the first three quarters of 2020 (intra-COVID-19) versus 2636 in 2019 (baseline), representing a 12.7% decline. Testing declined by 25% in women, 20% in children and 81% in community-initiated referrals. Notwithstanding, laboratory-confirmed TB cases increased by 37.0% and treatment success rate was higher in 2020 (55.6% vs. 46.7%, p = 0.002). Multivariate logistic regression analysis found that age < 55 years (aOR 1.74, 95% CI (1.80, 2.56); p = 0.005), new diagnosis (aOR 1.69, 95% CI (1.16, 2.47); p = 0.007), pulmonary TB (aOR 3.17, 95% CI (1.67, 6.04); p < 0.001), HIV negative status (aOR 1.60, 95%CI (1.24, 2.06); p < 0.001) and self-administration of anti-TB drugs through monthly dispensing versus directly observed therapy (DOT) (aOR 1.56, 95% CI (1.21, 2.03); p = 0.001) independently predicted treatment success. These findings may have policy implications for DOTS in this setting and suggest that more resources are needed to reverse the negative impact of the COVID-19 pandemic on TB program activities in Sierra Leone.

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Impact of financial leverage on profitability of listed manufacturing firms in China

Pacific Accounting Review ◽

10.1108/par-01-2018-0008 ◽

2018 ◽

Vol 30 (4) ◽

pp. 410-432 ◽

Cited By ~ 5

Author(s):

Ilhan Dalci

Keyword(s):

Financial Distress ◽

Fixed Effects ◽

Negative Impact ◽

Positive Impact ◽

Generalized Method Of Moments ◽

Manufacturing Firms ◽

Chinese Government ◽

Financial Leverage ◽

Content Type ◽

The Impact

PurposeThe purpose of the study is to explore how financial leverage influences profitability of 1,503 listed manufacturing firms in China.Design/methodology/approachThe sample of the study is composed of the listed manufacturing firms in China. For the manufacturing firms, the annual financial information from 2008 to 2016 is obtained from the ORBIS database. In this study, initially a simultaneous equation approach is used to control for potential endogeneity. Then, additional regression analyses are conducted with panel data over the period of 2008-2016 using OLS, Fixed-effects, First-difference, Random-effects and Arellano and Bond’s (1991) two-step Generalized Method of Moments (GMM) methods.FindingsThe results reveal that the impact of leverage on profitability is inverted U-shaped. In this inverted U-shaped relationship, the positive impact of financial leverage on profitability could be attributed to tax shield, whereas the negative impact might be because of bankruptcy cost, financial distress, severe agency problems and information asymmetry that the listed Chinese firms suffer from because of some institutional characteristics of China.Research limitations/implicationsFirst, this study focuses on only listed manufacturing firms in China. Second, ownership types are not taken into account in this study.Practical implicationsFirst, the Chinese government should direct its efforts toward developing the bond markets and promoting alternative privately owned loan creditors to state-owned banks. Parallel to this, the transformation process toward market economy should be accelerated to facilitate the privatization of state-owned enterprises (SOEs). In addition to this, development of the bond market and privatization of SOEs will also mitigate the agency conflict between creditors and managers and between shareholders and managers.Originality/valueTo the best of the author’s knowledge, this is the first study which investigates the impact of capital structure on profitability of the listed firms in China.

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