Review of Neurologic Comorbidities in Hospitalized Patients with Opioid Abuse

2021 ◽  
pp. 10.1212/CPJ.0000000000001080
Author(s):  
Kevin R. Nelson ◽  
Katelyn Dolbec ◽  
William Watson ◽  
Hanwen Yuan ◽  
Mam Ibraheem
Keyword(s):  
Disease Burden ◽  
Neuromuscular Disorders ◽  
Hospitalized Patients ◽  
Opioid Abuse ◽  
Central Nervous System Infections ◽  
Hospital Discharges ◽  
The Public ◽  
Urban Rural ◽  
One Year ◽  
Spine Disorders

AbstractPurpose of review:Determine the prevalence and burden of neurological comorbidities in hospitalized patients with opioid abuse.Recent findings:From one year of hospital discharges 2,182 opioid abuse patients were identified (prevalence 6.3%), with abuse greater among younger patients (p<0.0001), women (p<0.0001), whites (p<0.0001), and urban population (p=0.028). Matching for age, sex, race, and urban-rural residence, 347 patients were reviewed and 179 (52%) had a neurological comorbidity. The comorbidities frequently overlapped and included: encephalopathy (130), neuromuscular disorders (42), seizures (23), spine disorders (23), strokes (20), central nervous system infections (3), and movement disorders (2). Abuse patients with neurologic comorbidities experienced substantially greater number of hospital and intensive care unit days and mortality, independent of overdose.Summary:Neurological comorbidities are a frequent and heretofore underappreciated contributor to the disease burden of hospitalized patients with opioid abuse. The importance of neurological comorbidities should be included in the public health discussions surrounding the opioid epidemic.

scholarly journals Human Coronavirus Infections in Israel: Epidemiology, Clinical Symptoms and Summer Seasonality of HCoV-HKU1

Viruses ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 515 ◽  
Author(s):  
Nehemya Friedman ◽  
Hadar Alter ◽  
Musa Hindiyeh ◽  
Ella Mendelson ◽  
Yonat Shemer Avni ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Medical Center ◽  
Hospitalized Patients ◽  
Pcr Analysis ◽  
Virus Infections ◽  
Summer Period ◽  
The Public ◽  
Syncytial Virus ◽  
Human Coronaviruses ◽  
One Year

Human coronaviruses (HCoVs) cause mild to severe respiratory diseases. Six types of HCoVs have been discovered, the most recent one termed the Middle East respiratory syndrome coronavirus (MERS-CoV). The aim of this study is to monitor the circulation of HCoV types in the population during 2015–2016 in Israel. HCoVs were detected by real-time PCR analysis in 1910 respiratory samples, collected from influenza-like illness (ILI) patients during the winter sentinel influenza survey across Israel. Moreover, 195 HCoV-positive samples from hospitalized patients were detected during one year at Soroka University Medical Center. While no MERS-CoV infections were detected, 10.36% of patients in the survey were infected with HCoV-OC43 (43.43%), HCoV-NL63 (44.95%), and HCoV-229E (11.62%) viruses. The HCoVs were shown to co-circulate with respiratory syncytial virus (RSV) and to appear prior to influenza virus infections. HCoV clinical symptoms were more severe than those of RSV infections but milder than influenza symptoms. Hospitalized patients had similar HCoV types percentages. However, while it was absent from the public winter survey, 22.6% of the patients were HCoV-HKU1 positives, mainly during the spring-summer period.

Tax-Advantaged Trust Use Among IPO Executives: Determinants and Implications for Valuation and Future Performance

2019 ◽  
Vol 95 (3) ◽  
pp. 145-175 ◽  
Author(s):  
Michael J. Dambra ◽  
Matthew Gustafson ◽  
Phillip J. Quinn
Keyword(s):  
Stock Price ◽  
Relevant Information ◽  
Data Availability ◽  
Market Prices ◽  
The Public ◽  
Future Performance ◽  
Estate Taxes ◽  
Price Appreciation ◽  
One Year ◽  
Jel Classifications

ABSTRACT We examine the prevalence and determinants of CEOs' use of tax-advantaged trusts prior to their firm's IPO. Twenty-three percent of CEOs use tax-advantaged pre-IPO trusts, and share transfers into tax-advantaged trusts are positively associated with CEO equity wealth, estate taxes, and dynastic preferences. We project that pre-IPO trust use increases CEOs' dynastic wealth by approximately $830,000, on average. We next examine a simple model's prediction that trust use will be positively related to IPO-period stock price appreciation. We find that trust use is associated with 12 percent higher one-year post-IPO returns, but is not significantly related to the IPO's valuation, filing price revision, or underpricing. This evidence is consistent with CEOs' personal finance decisions prior to the IPO containing value-relevant information that is not immediately incorporated into market prices. JEL Classifications: D14; G12; G32; M21; M41. Data Availability: Data are available from the public sources cited in the text.

scholarly journals An Assessment on Bird’s Diversity in Bagmati River Corridor

1970 ◽  
Vol 2 (1) ◽  
pp. 34-40
Author(s):  
Saroj Thapa ◽  
Shambhu Paudel ◽  
Dipak BK
Keyword(s):  
Public Perception ◽  
Habitat Degradation ◽  
Bird Species ◽  
Habitat Destruction ◽  
Conservation Area ◽  
Point Count ◽  
The Public ◽  
One Year ◽  
Bagmati River ◽  
River Corridor

Bagmati River is considered as a potential conservation area in terms of the bio-diversity conservation due to its unique and diversified habitat distribution. Due to various causes, the river is being polluted and hence habitat degradation rate is increasing. As a consequence, the direct effect is seen on birds inhabiting there. Aiming the assessment of bird's diversity, one year survey was conducted in Bagmati River from Tilganga Bridge to chobhar Gorge Bridge (here after termed as Bagmati river corridor) by applying the point count method .In the total enumeration, 100 of birds species were recorded among which 7 are listed in CITES appendix. The bird species that are regarded as globally threatened are not recorded in the study area. In this report, some potential patches in the study area, are described as hot spots, considering the higher probability of recording maximum number of birds species. The public voice is also collected to find out the public perception on the present status of birds of Bagmati river corridor using the questionaire method. Some causes of habitat destruction and some potential conservation measures are also mentioned. Key Words: Bagmati river corridor, Birds, Conservation, Hotspots, Diversity, Habitat   DOI: 10.3126/init.v2i1.2520 The Initiation Vol.2(1) 2008 pp34-40

scholarly journals Communicative Constitution of Organization for Elementary School in Pandemic Covid-19

2021 ◽  
Vol 1 (4) ◽  
pp. 183-189
Author(s):  
Sigit Tri Pambudi ◽  
Basuki Agus Suparno
Keyword(s):  
Elementary School ◽  
Organizational Development ◽  
Teaching And Learning ◽  
Learning Processes ◽  
Important Thing ◽  
The Public ◽  
Communication Events ◽  
Communicative Constitution ◽  
One Year ◽  
The Way

This study focuses on an organizational development especially for an elementary school in which try to stabilize and adopt the changes of teaching and learning processes in relate to pandemic Covid 19 since it has been prevailing one year ago. Through Communicative Constitution of Organization (CCO) approach, it stressed on how elementary school as organization develop and adapt toward the uncertainty situation affected by pandemic covid 19. There are four locations which represent communication events in organization. First, membership negotiation, portraits how member of organization interact each other. Second, self- structuring, reflects how organization norms and culture were internalized within member of organization. Third, activity coordination- the way assignment was conducted and accomplished. It is an important thing in determine organization being successful. And finally, position of institution determines organization to the public. All has important roles to shape and develop organization being success.

scholarly journals Decomposing Urban-rural Differences in Multimorbidity Among Older Adults in India: A Study Based on Lasi Data

2021 ◽  
Author(s):  
Shekhar Chauhan ◽  
Shobhit Srivast ◽  
Pradeep Kumar ◽  
Ratna Patel
Keyword(s):  
Older Adults ◽  
Rural Areas ◽  
Urban Areas ◽  
Decomposition Analysis ◽  
The Public ◽  
Analysis Techniques ◽  
Ageing Study ◽  
Urban Rural ◽  
The Difference ◽  
Urban And Rural Areas

Abstract Background: Multimorbidity is defined as the co-occurrence of two or more than two diseases in the same person. With rising longevity, multimorbidity has become a prominent concern among the older population. Evidence from both developed and developing countries shows that older people are at much higher risk of multimorbidity, however, urban-rural differential remained scarce. Therefore, this study examines urban-rural differential in multimorbidity among older adults by decomposing the risk factors of multimorbidity and identifying the covariates that contributed to the change in multimorbidity.Methods: The study utilized information from 31,464 older adults (rural-20,725 and urban-10,739) aged 60 years and above from the recent release of the Longitudinal Ageing Study in India (LASI) wave 1 data. Descriptive, bivariate, and multivariate decomposition analysis techniques were used.Results: Overall, significant urban-rural differences were found in the prevalence of multimorbidity among older adults (difference: 16.3; p<0.001). Moreover, obese/overweight and high-risk waist circumference were found to narrow the difference in the prevalence of multimorbidity among older adults between urban and rural areas by 8% and 9.1%, respectively.Conclusion: There is a need to substantially increase the public sector investment in healthcare to address the multimorbidity among older adults, more so in urban areas, without compromising the needs of older adults in rural areas.

scholarly journals DU KAN IKKE TALE OM DAS BECKWERK; DU ER ALLEREDE I DAS BECKWERK

1970 ◽  
Vol 41 (115) ◽  
pp. 155-165
Author(s):  
Den navnløse tidligere leder af Das Beckwerk
Keyword(s):  
Public Spaces ◽  
The Public ◽  
One Year ◽  
The University

YOU CAN’T TALK ABOUT DAS BECKWERK; YOU ARE ALREADY IN DAS BECKWERK | Subjected to a one-year ban on performances in the public spaces of Scandinavia, the former CEO of the Copenhagen-based enterprise Das Beckwerk held a lecture on 9th December 2011 solely for the ears of the rising star of fictionality and narratology Richard Walsh from the University of York. The lecture dealt not only with the disappearing boundaries betweenreality and fiction but also with how novel characters have become legal citizens, while the author is turned into fiction. Finally the former CEO dismisses the judgment in the famous trial “Thomas Skade-Rasmussen Strøbech versus Gyldendal and Helge Bille Nielsen”. He calls it unjust and a neglect of the fictional character’s right to a personal name, story and picture.

The Manifestation of New Public Service Principles in Issuance of Emergency Use Authorization of COVID-19 Vaccine by BPOM

2021 ◽  
Vol 2 (2) ◽  
pp. 229
Author(s):  
Alexander Arie Sanata Dharma
Keyword(s):  
Public Service ◽  
Regulatory Authority ◽  
Vaccine Development ◽  
Secondary Data ◽  
Quality Standard ◽  
Sources Of Information ◽  
Health Crisis ◽  
The Public ◽  
New Public ◽  
One Year

The COVID-19 pandemic has lasted more than one year, and vaccines are the primary expectation of ending it. The vaccine development successfully accelerated from 10-15 years to only about 12-16 months through several adjustments. In a health crisis, the vaccine can be accepted through Emergency Use Authorization (EUA) by a country's regulatory authority. In Indonesia, the role is carried out by the Indonesia Food and Drug Administration (BPOM). This study proposes analyzing the manifestation of the principles of the New Public Service in issuing EUA for the COVID-19 vaccine. This research uses qualitative methods through secondary data analysis on written sources of information such as websites, reports, social media, books, and journals. Based on the analysis, in issuing the EUA COVID-19 vaccine, BPOM has performed the principles of the New Public Service. BPOM, with all stakeholders, insisted on their values (quality, safety, and efficacy) to facilitate the EUA process due to the urgency of the emergency. With this effort, the public can afford vaccines that safe and meet the efficacy and quality standard within the expected time.Keywords : COVID-19, Emergency Use Authorization, Indonesia FDA, New Public Service

The Impact of the PCAOB Triennial Inspection Process on Inspection Year and Non-Inspection Year Audits

2021 ◽  
Author(s):  
Lawrence J. Abbott ◽  
William L Buslepp
Keyword(s):  
Audit Quality ◽  
The Public ◽  
Learned Behavior ◽  
Public Company ◽  
Inspection Process ◽  
One Year ◽  
The Impact

The Public Company Accounting Oversight Board (PCAOB) inspects auditors with fewer than 100 publicly held clients, once every three years (i.e., triennial inspection). In doing so, the PCAOB may inspect any audit engagement within the three-year window, including audits completed only months earlier ("inspection year" audits) and audits with at least a one-year, if not two-year lag ("non-inspection year" audits). We theorize the triennial inspection process affects audit quality levels, whereby auditors impose higher (lower) audit quality during inspection years (non-inspection years). We find clients of triennially inspected auditors have significantly lower levels of accruals during inspection years. Further, this change can be attributed to additional audit effort expended during inspection years. Finally, we find some evidence this is a learned behavior developed after the initial round of inspections. Our evidence suggests auditors opportunistically increase (decrease) audit quality during inspection (non-inspection) years in response to the triennial inspection process.

Policing of Movie and Music Piracy

2013 ◽  
pp. 1144-1161
Author(s):  
Johnny Nhan ◽  
Alesandra Garbagnati
Keyword(s):  
File Sharing ◽  
Law Firms ◽  
Cultural Conflicts ◽  
The Public ◽  
Security Models ◽  
P2p File Sharing ◽  
Long Run ◽  
One Year ◽  
Pirate Bay

Ongoing skirmishes between mainstream Hollywood entertainment conglomerates and Peer-to-Peer (P2P) file-sharing networks recently reached a crescendo when a Swedish court convicted members of the world’s largest BitTorrent, The Pirate Bay, and handed out the stiffest sentence to date.1 Four operators of The Pirate Bay received one year imprisonments and fines totaling $30 million, including confiscation of equipment. While this verdict sent shockwaves amongst P2P networks, piracy remains rampant, and this incident further exacerbated relations between file sharers and Hollywood. In retaliation, supporters of P2P file-sharing attacked websites of the law firms representing the Hollywood studios (Johnson, 2009). This victory by Hollywood studios may be a Pyrrhic defeat in the long run if the studios do not soften their antagonistic relations with the public. This chapter explores structural and cultural conflicts amongst security actors that make fighting piracy extremely difficult. In addition, it considers the role of law enforcement, government, industries, and the general public in creating long-term security models.

scholarly journals Total hip arthroplasty and lumbar spine disorders: Plain co-existence or mutual influence?

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Nils Wirries ◽  
Michael Schwarze ◽  
Dorothea Daentzer ◽  
Michael Skutek
Keyword(s):  
Lumbar Spine ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Mutual Influence ◽  
Negative Impact ◽  
Clinical Signs ◽  
Clinical Results ◽  
Total Hip ◽  
One Year ◽  
Spine Disorders

Lumbar spine disorders (LSD) might influence the outcome after total hip arthroplasty (THA). Despite a known common prevalence of LSD and degenerative hip disorders, this study investigates their mutual influence in case of co-existence with the purpose to advance surgeons planning and patient’s prognosis. Patients with and without LSD were compared before and at the one-year postoperative examination. For clinical evaluation the WOMAC was assessed. The radiological analysis focused on cup anteversion and inclination. The total group included 203 consecutive patients. The overall incidence of LSD was 51.0%. Patients with LSD were on average 4.3 years older and had a 1.8 higher BMI than non-LSD patients (P<0.05). The cup positioning and the clinical results were comparable between both groups before and at the last time of follow up (P>0.05). No hip dislocations nor clinical signs of impingement were seen.We can conclude that there is a high degree of co-existence of LSD and hip disorders. However, a strong negative impact of LSD to clinical or radiologic results could not be confirmed in our study.

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