scholarly journals Análise do consumo de benzodiazepínicos em um município do norte do Rio Grande do Sul, Brasil

2020 ◽  
Vol 10 (1) ◽  
pp. 49
Author(s):  
Marisa Mosfiak ◽  
Fabíola Stolf Brzozowski ◽  
Luiz Carlos Cichota

Os benzodiazepínicos (BZD) são fármacos recomendados para o tratamento de transtornos de ansiedade e insônia, por um período curto de tempo. São bastante consumidos, especialmente no Brasil, entretanto podem levar a intoxicações e efeitos adversos significativos, além de dependência quando consumidos a longo prazo. Dessa forma, o objetivo deste trabalho foi traçar o perfil dos usuários de benzodiazepínicos em uma Unidade Básica de Saúde (UBS) de um município de pequeno porte, da região norte do Rio Grande do Sul, em 2019. Trata-se de estudo descritivo, utilizando como base questionário anônimo com 62 indivíduos em uso de BZD e análise de suas prescrições. Destaca-se a maior quantidade de mulheres, de pessoas baixa escolaridade e idade entre 41 e 70 anos, dentre os entrevistados. O clonazepam foi o fármaco mais prescrito. A maior parte dos entrevistados fazia uso desse tipo de substância há mais de 5 anos. Essa característica é preocupante e indica que os BZD estão sendo utilizados de maneira indiscriminada no município, assim como ocorre em outras cidades do país. Os profissionais de saúde precisam estar atentos para o uso apropriado de medicamentos, evitando, dessa forma, iatrogenias decorrentes desse uso. ANALYSIS OF BENZODIAZEPINE CONSUMPTION IN A CITY OF NORTHERN RIO GRANDE DO SUL, BRAZIL Benzodiazepines (BZD) are drugs used as short-term therapies for the treatment of anxiety and insomnia. BZD are highly consumed, especially in Brazil, however, its longterm consumption can lead to addiction. Thus, this paper aims to describe the profile of BZD users in a Health Center (HC) in a small city of Northern Rio Grande do Sul, Brazil, in 2019. A descriptive analysis was designed based on an anonymous questionnaire with 62 BZD users, in addition to analysis of their prescriptions. We highlight that the majority of subjects are women, people with poor schooling and age between 41 and 70 years old. Clonazepam was the most prescribed BZD. The majority of the respondents was takingBZD for more than 5 years. This indicates that BZD are being used indiscriminately in the studied city, as is the case in many other Brazilian cities. Health professionals need to be attentive to inappropriate use of these drugs, avoiding their iatrogenic effects.

2019 ◽  
Vol 47 ◽  
Author(s):  
Stéfano Leite Dau ◽  
Tanise Policarpo Machado ◽  
Ezequiel Davi Dos Santos ◽  
Diorges Henrique Setim ◽  
Eduardo Rebelato Sakis ◽  
...  

Background: In various regions of Brazil, horses and cattle are considered the most susceptible animals to plant poisoning. The plants of the genus Senecio are the most important in Rio Grande do Sul because they have the active principle known as the pyrrolizidine alkaloid. Its diagnosis is made through epidemiology, clinical signs and histopathological analysis, either of the tissues obtained by biopsy or necropsy. The objective of this study was to report and characterize the epidemiological, clinical and anatomopathological findings of three cases of natural poisoning by Senecio brasiliensis in horses assisted at the Hospital Veterinário (HV) of the Universidade de Passo Fundo (UPF).Cases: Three traction horses, two males and one female, were admitted at the HV-UPF for clinical care. The animals were presenting anorexia, weight loss, dysmetria, proprioceptive deficit and signs suggestive of colic. The epidemiological study revealed that the sites where these animals were located were infested by Senecio brasiliensis. The support therapy used for equine colic in all three cases was unsuccessful. One of the animals died and the other two were euthanized, all three of them being reffered for necropsy. The post-mortem findings were mainly found in the liver, which showed accentuation of the lobular pattern and the appearance of nutmeg. During necropsy, fragments of organs from thoracic and abdominal cavities and central nervous system were collected and fixed in 10% buffered formalin. Subsequently, the samples were processed chemically, submitted to cuts of five micrometers of thickness and stained with hematoxylin and eosin for microscopic analysis. Microscopically, the liver of all three horses presented megalocytosis, fibrosis and bile ducts hyperplasia. In the central nervous system, spongiosis and the presence of Alzheimer type II astrocytes were observed. Thus, through the association of information, the diagnosis of poisoning by Senecio brasiliensis was achieved.Discussion: The diagnosis of natural poisoning by Senecio brasiliensis was obtained through the epidemiological survey that showed S. brasiliensis in pastures where all three horses were allocated.  Cases of intoxication by S. brasieliensis in cattle are more frequent than in equines, although both species are considered the most susceptible. In horses, the main clinical manifestations observed include neurological disorders, apathy, anorexia, dysphagia, weight loss, subcutaneous edema and icterus. The clinical signs presented by the equines suggested initial signs of colic syndrome, although anorexia, weight loss, dysmetria and proprioceptive deficit are commonly observed in pyrrolizidine alkaloid poisoning in the liver, both in cattle and horses. The pyrrolizidine alkaloids present in the genus Senecio that become toxic when biotransformed in the liver into a pyrrholic form highly reactive that inhibits cell mitosis and leads to the onset of megalocytosis, cell death and liver fibrosis. The necropsy findings and histopathology were characteristic of poisoning in equines, since the predominant macroscopic lesions in the liver were hepatomegaly and accentuation of lobular pattern, whereas microscopically, there was a predominance of hepatic fibrosis, megalocytosis, spongiosis and the incidence of Alzheimer's type II astrocytes in the brain. These lesions are observed both in natural and in experimental cases of poisoning in horses. Thus, through the ante-mortem and complete post-mortem evaluation of the three equines, it was possible to establish the occurrence of natural poisoning by Senecio brasiliensis in Northern Rio Grande do Sul, as well as to characterize the epidemiological, clinical and anatomopathological findings of poisoning in this species.


2019 ◽  
Vol 3 ◽  
pp. 79
Author(s):  
Geraldine Alves dos Santos ◽  
Päivi Sanerma

ABSTRACTMany studies have been carried out, mainly in the last decades, to understand the normal and pathological process of aging in the different areas of knowledge. However, many gaps still remain in the progress of science. In this sense, the overall objective of the present study was to evaluate the comparison between the performance of congruent elderly people in Brazil and Finland. The study method had a quantitative, descriptive cross - sectional design. The sample consisted of 194 subjects of both sexes, aged between 60 and 79 years, residing in the municipality of Ivoti / Rio Grande do Sul / Brazil and 93 subjects, both genders aged 65 to 85 years residing in Riihimäki / Finland. The instrument used was the Mini Mental State Examination (MMSE). Data were analyzed statistically in SPSS version 25.0 through descriptive analysis of frequency and comparison of means by the Mann Whitney test (p≤0.05). The results showed that the cognitive performance of elderly people in the Ivoti group was significantly higher than those of Riihimäki. It can be concluded that cultural variables influenced outcomes, such as experiences in the early stages of human development and current interpersonal relationships.Keywords: Cognitive performance. Successful aging. Elderly. RESUMOMuitos estudos têm sido realizados, principalmente nas últimas décadas, para compreender o processo normal e patológico de envelhecimento, nas diferentes áreas do conhecimento. Entretanto, muitas lacunas ainda se mantêm presentes no progresso da ciência. Neste sentido, o objetivo geral do presente estudo foi avaliar a comparação entre o desemepnho congitivo de pessoas idosas residentes no Brasil e na Finlândia. O método do estudo teve um delineamento quantitativo, descritivo e transversal. A amostra compreendeu 194 sujeitos, de ambos os sexos, com idade entre 60 e 79 anos, residentes no município de Ivoti/Rio Grande do Sul/Brasil e 93 sujeitos, de ambos os sexos com idade entre 65 e 85 anos residentes em Riihimäki/Finlândia. O instrumento utilizado foi o Mini Exame do Estado Mental (MEEM). Os dados foram analisados estatisticamente no programa SPSS versão 25.0 através de análises descritivas de frequência e de comparação de médias pelo teste Mann Whitney (p≤0,05). Os resultados demonstraram que o desempenho cognitivo das pessoas idosas do grupo de Ivoti foi significativamente maior que os de Riihimäki. Pode-se concluir que variáveis culturais influenciaram os resultados, tais como experiências nas fases iniciais do desenvolvimento humano e as relações interpessoais atuais.Palavras-chave: Desempenho cognitivo. Velhice. Idosos.


2005 ◽  
Vol 3 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Vinicius A. Bertaco ◽  
Alexandre R. Cardoso

A new pseudopimelodid catfish, Microglanis malabarbai, is described from the rio Ijuí drainage, tributary of the middle rio Uruguay, Rio Grande do Sul, Brazil. The new species is distinguished from all other Microglanis species by the caudal fin color pattern, almost completely black, with a narrow vertical white band across central portions of the caudal-fin rays. Furthermore, it is distinguished from M. cottoides and M. eurystoma, both from rio Uruguay drainage, by head length, maxillary barbel length, internareal distance, and number of lateral-line pores, and from M. cibelae from the coastal drainages of northern Rio Grande do Sul and southern Santa Catarina states, by head length, maxillary barbel length, and body width. A key is presented for the species of Microglanis occurring in southern Brazil.


Author(s):  
Anibal Lopes Guedes ◽  
Fernanda Lopes Guedes ◽  
Ana Cristina Guedes Laimer

ABSTRACTEducational Robotics has come to prominence in recent years, allowing articulate a more playful and interactiveteaching. Abstract works in particular, and therefore stands as a new methodology of teaching andlearning. Therefore, this paper aims to present educational initiatives that use robotics in primary schools, located in the west of Santa Catarina and northern Rio Grande do Sul, Brazil. Initiatives Kerber (2009) Tosini and Holz (2010) and Zarpelon, Tortelli and Bieniek (2013 ) was used as instruments for direct observation of the school and, later, the intervention in the classroom. For this, the Lego Mindstorms NXT robotics kit was used. This kit was chosen because it contains a significant amount of gears, allows customization or manufacturing parts, programming is simplified through the use of visual programmable blocks. As a result, it was found that the technology allows integration, interaction, discussion and cooperation among students, faculty and staff, that somehow permeates individual and collective development, providing opportunities to improve educational processes.RESUMENRobótica Educativa ha llegado a la prominencia en los últimos años, ya que permite articular una enseñanza más lúdica e interactiva. Obras abstractas en concreto, y por lo tanto se erige como una nueva metodología de enseñanza y aprendi-zaje. Por lo tanto, este trabajo busca presentar iniciativas educativas que utilizan la robótica en las escuelas primarias, que se encuentra en el oeste de Santa Catarina y el norte de Rio Grande do Sul, en Brasil. En iniciativas Kerber (2009), Tosini y Holz (2010) y Zarpelon, Tortelli y Bieniek (2013) se utilizó como instrumentos para la observación directa de la escuela y, más tarde, la intervención en el aula. Para ello, se utilizó el kit Lego Mindstorms NXT robótica.  Este kit fue elegido debido a que contiene una cantidad significativa de engranajes, permite la personalización o la fabricación de piezas, su programación se simplifica mediante el uso de bloques programables visuales. Como resultados, se encontró que la tecnología permite la integración, interacción, discusión y cooperación entre estudiantes, profesores y empleados, que de alguna manera permea un desarrollo individual y colectivo, proporcionando oportunidades para la mejora de los procesos educativos.


2014 ◽  
Vol 62 (3) ◽  
pp. 267-274
Author(s):  
Fernando Stumpf BÖCKMANN ◽  
Bruna Barnard MOTTA ◽  
Jerônymo Maciel CAMARGO ◽  
Paulo Cauhy PETRY ◽  
Ramona Fernanda Ceriotti TOASSI

OBJECTIVE: We analyze the socio-demographic profile of the dentistry graduates at the Universidade Federal do Rio Grande do Sul, 2010-2011, the reasons which led them to choose Dentistry, appreciation for the course, as well as job prospects and Graduate studies. METHODS: Cross-sectional, observational study Dentistry graduates, classes of 2010-2/ 2011-1 (n=76, 90.5% response rate). Data collection took place through the giving of a structured and anonymous pre-tested questionnaire. Results were grouped in tables and graphs by means of the distribution of the frequency of variables studied (descriptive analysis), with the assistance of the Statistical Package for the Social Sciences (SPSS) for Windows 17.0. This Study was approved by the Committee on Ethics in Research of the Universidade Federal do Rio Grande do Sul (18249). RESULTS: The classes of 2010-2/ 2011-1 Dentistry Graduates of the Universidade Federal do Rio Grande do Sul, were, in their majority, women, young, single, childless, natives of the State of Rio Grande do Sul, with a monthly salary income of 10 to 20 minimum salaries and without the presence of dentists in the family. More than 90% of these students were satisfied with the choice of Dentistry. They opted for the course especially due to personal as well as professional success, followed by security and peace of mind and financial comfort. The great part of the students evaluated the course as good or excellent. They intend, as a majority, to work in the public service as well as private practice and graduate work, particularly, specialization. CONCLUSION: Results identified the profile of the classes of 2010-2/ 2011-1 Dentistry graduate of the Universidade Federal do Rio Grande do Sul, classes of 2010-2/2011-1. It has been recommended that there be a permanent follow up of the graduates as an important instrument for monitoring the students as well as the development of the current integrated curriculum.


Check List ◽  
2009 ◽  
Vol 5 (4) ◽  
pp. 819 ◽  
Author(s):  
Dayana Bonfantti ◽  
Rocco Alfredo Di Mare ◽  
Ricardo Giovenardi

Aiming to contribute to the knowledge concerning diversity of the butterflies in the Atlantic Rainforest of the state of Rio Grande do Sul, a systematic survey was carried out in the city of Frederico Westphalen from November 2006 to June 2007, in two sampling localities. The total sampling efforts was 80 h, in which 1.785 samples were recorded, distributed in 161 species. From the latter, 51.57 % (83) belongs to the Nymphalidae family, Hesperiidae 20.49 % (33), Pieridae 8.69 % (14), Riodinidae 6.83 % (11), Papilionidae 6.21 % (10), Lycaenidae 6.21 % (10). Regarding the sampled species, 79.50 % (128) were recorded at both studied sites.


Biotemas ◽  
2015 ◽  
Vol 28 (3) ◽  
pp. 187
Author(s):  
Caroline Badzinski ◽  
Daniel Galiano ◽  
Bruno Busnello Kubiak ◽  
Cassiano Estevan ◽  
Jorge Reppold Marinho

2021 ◽  
Author(s):  
Gabriela Döwich Pradella ◽  
Claudia Acosta Duarte ◽  
Taiane Acunha Escobar ◽  
Luísa Zuravski ◽  
Geórgia Camargo Góss ◽  
...  

Abstract Background: Leishmaniasis, zoonotic diseases, are in the top ten list of tropical neglected disease globally. The number of contaminated dogs in South America is estimated in millions of animals and correlated to the human’s cases, especially in Brazil. Equines became infected too and can play a role in the epidemiological chain. Thus, the aim of the present study was to evaluate risk factors to leishmaniasis in rural areas of the western border region of Rio Grande do Sul state, Brazil by Leishmania sp. protozoa molecular detection and serological evaluation (ELISA) in equine and canine blood samples. Methods: This work included nine farms around the city of Uruguaiana. It was collected epidemiologic information regarding farm characteristics and biologic material collection of canine and equine, totalizing 113 samples. The polymerase chain reaction (PCR) technique was used to detect Leishmania spp. in biological samples. Variables related to the farm were collected and evaluated through descriptive analysis followed by chi-square test and a logistic regression analysis.Results: Nineteen positive samples (19/113 – 16,81%) were detected, being 18 equines and 1 canine, in six of the nine farms included in the study. No animal showed clinical signs of the disease. According to the variables analyzed, when compared each characteristic separately, the presence of abundant vegetation and poor hygiene demonstrated to be risk factors to Leishmania infection in rural areas. The logistic regression showed that excellent general hygiene, proximity to the weir and trimmed grass were protective factors (p=0.038, p=0.001 and p=0.014, respectively). Having excellent hygiene represents a 70% lower chance of getting contaminated, keeping the grass cut protects the animal by more than 90% and the proximity of the weir represents a protective factor of 96%.Conclusions: The presence of leishmaniasis in the western border region of Rio Grande do Sul was 16,81% and it was influence by farm characteristics. The role of the excellent general hygiene as a protective factor is extremally relevant in the leishmaniosis prevention.


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