scholarly journals Correlation between lipid profile and C-reactive protein in children with nephrotic syndrome

2015 ◽  
Vol 55 (1) ◽  
pp. 1
Author(s):  
Kurnia Dwi Astuti ◽  
Mohammad Heru Muryawan ◽  
Omega Mellyana
Keyword(s):  
Nephrotic Syndrome ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Sensitivity ◽  
Active Phase ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Positive Correlation

Background Nephrotic syndrome (NS) causes dyslipidemia in children, which can be long term or intermittent. Dyslipidemia has long been established as a risk factor for atherosclerosis. An early sign of atherosclerosis is elevated high sensitivity C-reactive protien (hsCRP). Atherosclerosis early in life, especially in childhood, warrants an assessment for NS. Study on a correlation between lipid profile and hsCRP, as a marker of atherosclerosis, in pediatric NS patients has been limited. Objective To assess for a correlation between lipid profile and hsCRP in childhood nephrotic syndrome. Methods This cross-sectional study was undertaken on 29 children with NS in Dr. Kariadi Hospital. Serum hsCRP, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) were examined in the active phase. Spearman’s test was used to analyze a possible correlation between total cholesterol, LDL, HDL and hsCRP levels. Results Mean levels of total cholesterol (454 mg/dL) and LDL (288 mg/dL) in this study were high, while the HDL level (55 mg/dL) was normal, according to US Department of Health and Human Services classifications. The median hsCRP level was 0.33 mg/L and 9 (31%) subjects had high hsCRP levels of more than 1 mg/L. There was a positive correlation between LDL level and hsCRP (r=0.423; P<0.05). Conclusions There is a weak positive correlation between LDL and hsCRP levels in children with NS.

scholarly journals Pattern of dyslipidemia in hypothyroid patients: A cross sectional study

2016 ◽  
Vol 6 (2) ◽  
pp. 156
Author(s):  
K. G. Kibria ◽  
M. R. Alam ◽  
H. K. Paul ◽  
M. Fariduddin ◽  
M. A. Hasanat
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Thyroid Function ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Thyroid Function Tests ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hypothyroid Patients

<p><strong>Background:</strong> An association between thyroid dysfunction and dyslipidemia prevails. Levels of total cholesterol, low density lipoprotein cholesterol, triglycerides tend to increase as thyroid function declines.</p><p><strong>Objective:</strong> To find out the pattern of dyslipidemia in hypothyroid patients. <strong></strong></p><p><strong>Methods:</strong> Sixty cases were selected as a sample of convenience in this cross sectional study from in-patienl depa1tment of Medicine and Endocrinology, BSMMU. Meticulous history taking and thorough clinical examinations were done. Report of lipid profile and thyroid function tests were recorded from patients file. All the information's were recorded in a pre-designed sttuctured questionnaire. Collected data were classi­fied, edited, coded and entered into the computer for statistical analysis by using SPSS. <strong></strong></p><p><strong>Results:</strong> Among the 60 cases, 43 (72%) were female; 17(28%) were male. Age range was 24-59 years with a mean age of 38.80 (± I 0.35) years. Majority 38(65%) were housewife, followed by service holder 11(18.33%), 08(13.3%) were business men and 02(3.3%) had other occupations. Majority 42(70%) patients were taking thyroxin. Mean Total cholesterol (TC), LDL cholesterol, Triglycer­ide (TG) and HDL were 222.20(±42.25); 138.63(±31.51); 243.36(±83.13) and 37.30(±5.12) respectably. <strong></strong></p><p><strong>Conclusion:</strong> All hypothyroid subjects had dyslipidemia. The present study indicated that hypothyroidism was associated with an abnormal lipid profile, especially with respect to the levels of total cholesterol and triglyceride.</p>

scholarly journals A LIPID PROFILE STUDY AMONGST THE CASES OF TYPE 2 DIABETES MELLITUS - A CROSS SECTIONAL STUDY

2020 ◽  
pp. 27-28
Author(s):  
Divya Sinha ◽  
S. R. Padmeodev ◽  
Debarshi Jana
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional

Introduction: India leads the world with largest number of diabetic cases and is often referred to as the diabetes capital. Diabetic dyslipidemia in India is one of the main causes for Coronary Artery Disease (CAD) mortality of the world. Dyslipidemia are disorders of lipoprotein metabolism, including lipoprotein overproduction or deficiency. It is a preventable risk factor which is mostly observed in diabetes cases and that may precipitate the cardiovascular disorders. Our aim of the study is to determine the impact of type 2 diabetes mellitus (T2DM) on lipid profile of diabetic cases reporting at tertiary care hospital. Materials and methods: It was a cross sectional study conducted at Department of Biochemistry, Patna Science College, Patna, Bihar. Total 140 diabetic cases were randomly selected and they were examined for dyslipidemia. Fasting blood glucose concentration and Lipid Profile [Total Cholesterol (TC), High Density Lipoprotein (HDL), Very Low Density Lipoprotein (VLDL) and Triglycerides (TG)] were investigated by using commercially available reagent kits in Biochemistry analyzer. Collected data was analyzed by using appropriate software. Results: Out of total 140 diabetic cases examined, the mean age of cases was 48.93 ± 12.1 years. In present study we found the mean Fasting Blood Sugar (FBS) was 188.76 ± 54.63 mg/dl. The prevalence rates in our study for high Total Cholesterol (TC) and Triglycerides (TG) were 13.6% and 41.4% respectively. The prevalence rates for high LDL-C, very high LDL-C and low HDL-C in the diabetic subjects were 8.6%, 5.0% and 72.9% respectively. Conclusion: The diabetic cases had elevated serum total cholesterol, elevated triglyceride (triacylglycerol) and slightly elevated low density lipoprotein (LDL-C) and reduced levels of high density lipoprotein (HDL-C) indicating that diabetic cases were more prone to cardiovascular diseases. Type 2 Diabetes Mellitus, Dyslipidemia, Triglyceride, HDL-C, LDL-C, Total Cholesterol.

scholarly journals Prevalence of dyslipidemia in young adults.

2020 ◽  
Vol 27 (05) ◽  
pp. 987-993
Author(s):  
Mir Tahir Hussain Talpur ◽  
Muhammad Tauqeer Katbar ◽  
Khalil Ullah Shabir ◽  
Kashif Ullah Shabir ◽  
Uzair Yaqoob ◽  
...  
Keyword(s):  
Young Adults ◽  
Lipid Profile ◽  
Serum Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Institutional Review ◽  
Low Hdl ◽  
Males And Females

Objectives: This study will help us to understand what lipid profile is normally present in our population, if abnormal, timely screening, education, and proper management can be done. Study Design: Cross-sectional study. Setting: Jinnah Postgraduate Medical Centre (JPMC), Karachi, Pakistan. Period: November 2018-April 2019. Material & Methods: For the lipid profile, intravenous blood samples were collected in testing bottles after overnight fasting of 9-12 hours and sent to the institutional laboratory for testing. Dyslipidemia was defined as abnormal levels of any of the following components of the lipid profile. Total cholesterol of <200mg/dL was considered “desirable” while that of >240mg/dL was termed as hypercholesterolemia. High-density lipoprotein (HDL) was considered as “low” when it was <40mg/dL while Low-density lipoprotein (LDL) was considered as “optimal” when it was less than 100 mg/dL. Triglycerides level >150 mg/dL was identified as hypertriglyceridemia. We defined isolated dyslipidemias as abnormal levels of any of these. This study was assessed and approved by the institutional review board of JPMC. Results: 112 participants of age <40 and >20 years were registered with 62 males and 50 females. Prevalence of dyslipidemia was found to be 75.9% with significantly high percentage in females (p < 0.05). 55.4% of the participants had desirable serum cholesterol and 42.9% had hypertriglyceridemia. 58% of these had HDL levels <40 mg/dL while 18.8% had high LDL levels. The mean serum cholesterol was significantly different in males and females (p=0.018). 7.1% of the total had isolated hypertriglyceridemia, 18.8% had isolated low HDL levels, and 46.4% had mixed hyperlipidemia, with significant differences between males and females in the former two. Conclusion: Dyslipidemia is a major risk factor for numerous systemic disorders and should be detected early in life for an effective management prior to the appearance of symptoms. This study gave a high prevalence of dyslipidemia in asymptomatic young adults, with females being more frequently affected than females.

scholarly journals Hubungan paparan bising dan profil lipid dengan gangguan pendengaran pada pekerja pabrik minyak goreng

2016 ◽  
Vol 46 (1) ◽  
pp. 1
Author(s):  
Adlin Adnan ◽  
Renold Yurensa
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Noise Exposure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Study Data ◽  
High Density ◽  
Average Intensity ◽  
Cross Sectional

Latar belakang: Gangguan pendengaran akibat bising (GPAB) adalah komplikasi yang palingumum disebabkan oleh paparan terhadap bising, meskipun ada beberapa komplikasi lain yang bisadisebabkan oleh paparan bising. Komplikasi metabolik dari paparan terhadap bising telah dievaluasi olehberbagai penelitian.Tujuan: Meneliti hubungan antara GPAB dengan kadar profil lipid pada pekerja yangterpapar bising di lingkungan kerja.Metode: Penelitian ini bersifat deskriptif analitik dengan desain crosssectional study. Data diperoleh melalui proses wawancara, pemeriksaan audiometri, dan pemeriksaankadar profil lipid.Hasil: Rerata intensitas kebisingan bagian proses 98 dB, dan non-proses berkisar 46-98 dB. Berdasarkan hasil pemeriksaan audiometri terhadap 50 pekerja yang memenuhi kriteria inklusidan eksklusi, didapatkan 26 orang (52%) dengan GPAB tuli sensorineural dan 24 orang (48%) tidakmengalami GPAB. Kami menemukan hubungan signifikan antara paparan bising pada pekerja denganpeningkatan kadar trigliserida (TG), total kolesterol (TC), low-density lipoprotein (LDL), dan penurunankadar high-density lipoprotein (HDL) (p<0,05). Terdapat hubungan antara kadar TG yang tinggi terhadapterjadinya GPAB pada pekerja yang terpapar bising dengan intensitas >85 dB (p<0,05) dan tidak dijumpaihubungan peningkatan kadar TC, LDL, dan penurunan kadar HDL terhadap terjadinya GPAB (p>0,05).Kesimpulan: Pada penelitian ini, ada hubungan antara hiperlipidemia dengan GPAB. Pekerja denganhipertrigliseridemia yang tepapar bising >85 dB berisiko lebih besar menderita GPAB. Kata kunci: Kebisingan, GPAB, profil lipid ABSTRACTBackground: Noise induced hearing loss (NIHL) is the most common complication that causedby noise exposure, although there are other complications as a result of noise exposure. Metaboliccomplications from noise exposure have been evaluated in various studies. Purpose: To examine therelationship between NIHL with lipid profile in workers who are exposed to noise in workplace. Methods:The study design was analytic descriptive with cross-sectional study. Data collection was done throughinterviews, audiometry screening, and lipid profile examinations. Results: The average intensity in processsection was 98 dB, and in non-process section ranged between 46-98 dB. The results of audiometricexamination of the 50 workers who met the inclusion criteria, were 26 persons (52%) with sensorineuralNIHL and 24 persons (48%) did not experience NIHL. We found a significant association between noiseexposure among workers with elevated levels of triglyceride (TG), total cholesterol (TC), low-densitylipoprotein (LDL), and decreased high-density lipoprotein (HDL) levels (p<0,05). There was highcorrelation beween TG levels with the NIHL among workers who are exposed to noise >85 dB (p<0,05),and no correlation between elevated levels of TC, LDL and decreased HDL levels with NIHL (p>0,05).Conclusion: We found a significant relationship between hyperlipidemia and NIHL. Workers withhypertriglyceridemia had greater risk of suffering NIHL when exposed to noise >85 dB in the workplace. Keywords: Noise, NIHL, lipid profile

scholarly journals Study of Lipid profile in a population of university students

2013 ◽  
Vol 21 (5) ◽  
pp. 1151-1158 ◽  
Author(s):  
Roberto Wagner Junior Freire de Freitas ◽  
Marcio Flavio Moura de Araujo ◽  
Adman Camara Soares Lima ◽  
Dayse Christina Rodrigues Pereira ◽  
Ana Maria Parente Garcia Alencar ◽  
...  
Keyword(s):  
University Students ◽  
Lipid Profile ◽  
Clinical Laboratory ◽  
Demographic Data ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Blood Collection ◽  
Young Population ◽  
Cross Sectional

OBJECTIVE: to evaluate the lipid profile in a population of university students. METHODS: cross-sectional study with 702 students, of both genders enrolled in various courses at a public university in Fortaleza-CE. The demographic data and data on lifestyle habits were collected through a self-administered questionnaire. The blood collection was performed in a clinical laboratory. RESULTS: showed a predominantly young population, with a mean age of 21.5 years with more females (62.7%). High levels of triglycerides, total cholesterol and cholesterol associated with low density lipoprotein (LDL-c) were found in 23.0%, 9.7% and 5.9% of students, respectively. The cholesterol associated with high density lipoprotein (HDL-c) was at reduced values in 12.0% of subjects and was significantly associated with smoking (p=0.0231) and physical inactivity (p=0.0357). CONCLUSION: changes in lipid profile are present in the young population and intervention studies should be encouraged in order to reduce the prevalence of cardiovascular disease in adulthood.

scholarly journals Prevalence and factors associated with dyslipidemia after liver transplantation

2014 ◽  
Vol 60 (4) ◽  
pp. 365-372 ◽  
Author(s):  
Hélem de Sena Ribeiro ◽  
Lucilene Rezende Anastácio ◽  
Lívia Garcia Ferreira ◽  
Érika Barbosa Lagares ◽  
Agnaldo Soares Lima ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Multivariate Statistical ◽  
Cross Sectional ◽  
Factors Associated ◽  
Modifiable Factors ◽  
Low Hdl

Objective: to determine the prevalence of abnormal total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides in patients undergoing liver transplantation (LTx) and to identify predictors of these disorders. Methods: cross-sectional study to assess the prevalence of dyslipidemia in patients undergoing LTx. Demographic, socioeconomic, clinical, anthropometric and dietetic data were collected to determine the association with dyslipidemia using univariate and multivariate statistical analysis. Results: 136 patients were evaluated, 68.1% of which had at least one type of dyslipidemia. The triglyceride level was high in 32.4% of cases, with low HDL in 49.3% of patients and high LDL levels in only 8.8%. High total cholesterol was observed in 16.2% of the study population and was associated with the recommendation for transplantation due to ethanolic cirrhosis (OR = 2.7) and a greater number of hours slept per night (OR = 1.5). Conclusion: many patients presented dyslipidemia after transplantation, demonstrating the need for interventions in relation to modifiable factors associated with dyslipidemias that can mitigate or prevent these disorders.

scholarly journals Biomarkers of lipid metabolism in patients with juvenile idiopathic arthritis: relationship with disease subtype and inflammatory activity

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Wellington Douglas Rocha Rodrigues ◽  
Roseli Oselka Saccardo Sarni ◽  
Fernando Luiz Affonso Fonseca ◽  
Annelyse Araújo ◽  
Claudio Arnaldo Len ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Apo B ◽  
Systemic Jia ◽  
Disease Subtype ◽  
Low Hdl

Abstract Background To describe the biomarkers of lipid metabolism in children and adolescents with polyarticular and systemic JIA and to relate them to diseases subtypes, diseases activity markers, and nutritional status. Methods A cross-sectional study including 62 JIA patients was performed. The following variables were evaluated: disease activity and medications used, body mass index, height for age (z-score), skin folds (bicipital, tricipital, subscapular and suprailiac), food intake based on three 24-h food recalls, lipid profile (total cholesterol (CT), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG) and non-HDL (N-HDLc), glycemia and insulin, erythrocyte sedimentation rate (ESR), ultrasensitive C-reactive protein (us-CRP) and apolipoproteins A-I and B (Apo A-I and Apo B). Results Dyslipidemia was observed in 83.3% of the patients. Based on classical lipid profile, low HDL-c levels was the most frequently alteration observed. Inadequate levels of LDL-c, Apo B and NHDL-c were significantly more frequent in the systemic JIA subtype when compared to the polyarticular subtype (p = 0.017, 0.001 and 0.042 respectively). Patients on biological therapy had a better adequacy of Apo A-I concentrations. The ESR showed a negative correlation with Apo A-I level (r = − 0.25, p = 0.047). Conclusion We concluded that dyslipidemia is common in patients with JIA, especially in systemic subtype. The systemic subtype and an elevated ESR were associated with lower concentrations of Apo A-I, suggesting the participation of the inflammatory process.

scholarly journals HUBUNGAN ASUPAN SERAT DENGAN STATUS GIZI DAN PROFIL LIPID DARAH PADA ORANG DEWASA DISLIPIDEMIA

2014 ◽  
Vol 8 (3) ◽  
pp. 195
Author(s):  
Lilik Kustiyah ◽  
Maya Utami Widhianti ◽  
Mira Dewi
Keyword(s):  
Nutritional Status ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Cross Sectional Survey ◽  
Blood Lipid Profile ◽  
Cross Sectional

The objective of this study was to analyze the association of fiber consumption with nutritional status and blood lipid profile in dyslipidemic adults. The design study was cross sectional survey involving 79 subjects. The results showed that there were significant correlations between energy intake with High Density Lipoprotein (HDL) cholesterol and total cholesterol, fat intake with BMI (Body Mass Index), and BMI with Low Density Lipoprotein (LDL) cholesterol and total cholesterol (p&lt;0.05). There was no significant correlation between consumption of fiber with nutritional status and blood lipid profile (p&gt;0.05). In conclusion, most of the dyslipidemia subjects were obese. Dyslipidemia subjects should keep their intake of energy and fat in recommended ranges in order not to be obese and keep the BMI in normal range to avoid abnormalities of blood lipid profile.<br /><br />

scholarly journals Biomarkers of lipid metabolism in patients with juvenile idiopathic arthritis: relationship with subtype and inflammatory activity

2020 ◽  
Author(s):  
Wellington Douglas Rocha Rodrigues ◽  
Roseli Oselka Saccardo Sarni ◽  
Fernando Luiz Affonso Fonseca ◽  
Annelyse Araujo ◽  
Claudi Arnaldo Len ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Apo B ◽  
Systemic Jia ◽  
Low Hdl ◽  
Food Recalls

Abstract Background: To describe the biomarkers of lipid metabolism in children and adolescents with polyarticular and systemic JIA and to relate them to diseases subtypes, diseases activity markers, and nutritional status. Methods: A cross-sectional study including 62 JIA patients was performed. The following variables were evaluated: disease activity and medications used, body mass index, height for age (z-score), skin folds (bicipital, tricipital, subscapular and suprailiac), food intake based on three 24-hour food recalls, lipid profile (total cholesterol (CT), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG) and non-HDL (N-HDLc), glycemia and insulin, erythrocyte sedimentation rate (ESR), ultrasensitive C-reactive protein (us-CRP) and apolipoproteins A-I and B (Apo A-I and Apo B).Results: Dyslipidemia was observed in 83.3% of the patients. Based on classical lipid profile, low HDL-c levels was the most frequently alteration observed. Inadequate levels of LDL-c, Apo B and NHDL-c were significantly more frequent in the systemic JIA subtype when compared to the polyarticular subtype (p = 0.017, 0.001 and 0.042 respectively). Patients on biological therapy had a better adequacy of Apo A-I concentrations. The ESR showed a negative correlation with Apo A-I level (r = -0.25, p = 0.047).Conclusion: We concluded that dyslipidemia is common in patients with JIA, especially in systemic subtype. The systemic subtype and an elevated ESR were associated with lower concentrations of Apo A-I, suggesting the participation of the inflammatory process.

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