scholarly journals Host factors related to pneumonia in children under 5 years of age

2015 ◽  
Vol 55 (5) ◽  
pp. 248 ◽  
Author(s):  
Wiharjo Hadisuwarno ◽  
Retno Asih Setyoningrum ◽  
Pirlina Umiastuti

Background Pneumonia has been one of the serious problems for children under five in Indonesia. Imbalanced interactions among host factors, agents, and environments influence incidence of pneumonia. Objective To determine the risks of the host related to the incidence of pneumonia in children aged 3-59 months in Pediatrics Department, Dr. Soetomo General Hospital during 2011-2012. Methods This was a case control study on medical records of patients with respiratory infections in Pediatrics Department, Dr. Soetomo General Hospital. We grouped patients with pneumonia as the case group and patients with other respiratory infections as the control group. The data were statistically processed to calculate odds ratios and P values. Results There were 326 subjects reviewed, 163 in the case group and 163 in the control group. Host factors that increased the risk of pneumonia were: low birth weight (OR=3.10; 95%CI 1.34 to 6.86), inadequate exclusive breastfeeding (OR=1.7; 95%CI 1.09 to 2.64), malnutrition (OR=3.44; 95%CI 2.12 to 5.58) and incomplete immunization in a certain period of age (OR=2.70; 95%CI 1.72 to 4.24). Existed comorbidity was unrelated to the incidence of pneumonia (OR=1.53; 95%CI 0.86 to 2.71). Conclusion Low birth weight, inadequate exclusive breastfeeding, malnutrition, and incomplete immunization in a certain period of age increase the risk of pneumonia.

2018 ◽  
Vol 5 (2) ◽  
pp. 617
Author(s):  
Malavika P. Santappanavar ◽  
Habeeb U. Khan ◽  
Jaidev M. D. ◽  
Pavan Hegde

Background: More and more women are focusing on obtaining higher education and reaching career objectives. This has in turn, lead to delayed marriage and child birth at a later age. Advanced maternal age at birth has been found to be associated with preterm delivery, low birth weight, intrauterine fetal death and increased perinatal morbidity and mortality. The aim of our study was to know the neonatal outcome in elderly mothers and young mothers, and to compare the neonatal outcome of these two groups. Methods: Present study was a cross sectional, analytical case control study, done in babies delivered to mothers >35 years and <35 years. Information like period of gestation, birth weight, APGAR at 1 minute and 5 minutes, NICU admissions, neonatal outcome like respiratory distress, jaundice, convulsion, etc. were recorded in a proforma. Collected data was analysed using appropriate statistical tests.Results: In the present study, total sample size was 460 (230 cases and 230 controls). Incidence of preterm deliveries, Low birth weight, NICU admissions were significantly more in case group (babies born to mothers >35 years) than the control group (babies born to mothers between 19 to 35 years).Conclusions: It was observed that low birth weight, prematurity and NICU admissions were more common in babies born to elderly mothers.


2018 ◽  
Vol 58 (3) ◽  
pp. 123-7 ◽  
Author(s):  
Endang Dewi Lestari ◽  
Faraissa Hasanah ◽  
Novianti Adi Nugroho

Background Indonesia is ranked fifth in the world for the problem of stunting. Stunting in children under the age of five requires special attention, due to its inhibiting effect on children’s physical and mental development. Stunting is caused by several factors, one of which is breastfeeding. Stunting has been associated with several factors, one of which is non-exclusive breastfeeding. Objective To determine the correlations between non-exclusive breastfeeding and low birth weight to stunting in children aged 2-5 years. Methods This case-control study was conducted in October to November 2016 in multiple integrated health service clinics (posyandu) in Sangkrah, Surakarta, Central Java, Indonesia. Subjects were children aged 24-59 months who visited the posyandu and were included by purposive sampling. Children classified as stunted were allocated to the case group, whereas the children classified with normal nutritional status were allocated to the control group. Parents filled questionnaires on history of exclusive breastfeeding, child’s birth weight, maternal education, and family socio-economic status. Results Of the 60 subjects, the control group had 30 normal children and the case group had 30 stunted children. Multivariate analysis by logistical regression test revealed statistically significant correlations between stunting and non-exclusive breastfeeding (adjusted OR for exclusive breastfeeding 0.234; 95%CI 0.061 to 0.894), as well as low birth weight (adjusted OR 10.510; 95%CI 1.180 to 93.572) This value implies that exclusive breastfeeding is a protecting factor against stunting, which means exclusive breastfeeding is able to decrease the prevalence of stunting in children under the age of five. Conclusion In children aged 2-5 years, the histories of non-exclusive breastfeeding and low birth weights are significantly correlated sith stunting.    


Author(s):  
Mandana Kashaki ◽  
Arash Bordbar ◽  
Ali Mazouri ◽  
Nikta Nikbakht ◽  
Babak Jafarvand

Objective: The aim of this study was to determine the effect of high dose intralipid in compared to its gradual dose in very low birth weight newborns in Iran.  Methods: This study was a case-control study that conducted on 104 very low birth weight infants (<1500 g) referred to Akbarabadi hospital of Tehran (Iran) in 2016. The infants were randomly assigned to two groups (case group: 52 vs. control group: 52). The control group received intralipid 20% with a dose of 1 g/kg/24 h in the first and second day of the study, then from 3rd day to 3 g/kg /24h was raised. But, the case group received 3 g/kg/24 h of intralipid 20% from the first day and continued until the end of the study. In both groups, the study lasted for up to 30 days. Data were collected and analyzed using SPSS22 software. Also P-Value <0.05 was considered as a significant level. Results: The results showed mean daily weight gain in case group is higher than control group and this difference was significant statistically (P-Value < 0.05). Also, although the mean of blood sugar, triglyceride, HCO3, the number of positive blood culture and the number of positive CPR in case group were higher than control group, but these differences were not statistically significant (P-Value >0.05). Conclusion: Given that the better and faster growth of newborns in the intralipid group with high-dose in compared to intralipid group with gradual dose, the use of higher initial doses is recommended in newborns with very low birth weight.


Author(s):  
Annibal Sabino ◽  
Eduardo de Souza ◽  
Ana Goulart ◽  
Adriana Lima ◽  
Nelson Sass

Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.


2020 ◽  
Author(s):  
Mussie Mulugeta Gebremedhin ◽  
Mengistu Welday Gebremichael ◽  
Berhane Gebreegizabiher Gebremichael ◽  
Mihrete-ab Mehari Reda ◽  
Tesfay Adhena Hailu ◽  
...  

Abstract BACKGROUND: The Apgar score is a method to quickly summarize the health of newborn children. It establishes a simple and clear classification of newborns, which could be used to predict survival and to compare methods of resuscitation and perinatal experience across hospitals and obstetric practices. Low Apgar score is associated with various immediate and long-term adverse health outcomes of newborns. Hence; in order to decrease the risk/complications, identifying the determinant factors of low Apgar is crucial to act on the modifiable risk factors. This study is aimed to investigate the determinant factors of a low Apgar score in newborn children.METHOD: The study was conducted in Lemelem Karl general hospital; northern Ethiopia. An institutional-based unmatched, case-control study was implemented. Data were retrieved from medical charts of 662 newborns’ mothers who gave birth in the hospital from Sep 2014 to Sep 2017. Among these, 221 of them were cases (charts of mothers whose newborns’ fifth minute Apgar score was <7) and 441 of them were controls (charts of mothers whose newborns’ Apgar score was 7 and above). Data was collected using a pretested and structured checklist using systematic sampling and data was entered & analyzed using SPSS version 20. Binary and multivariable logistic regression was done to determine the association and statistical significance was declared at P-value of ≤0.05. RESULTS: This study revealed that low Apgar score was significantly associated with antepartum hemorrhage [Adjusted odss ratio (AOR) 3.509; 95% confidence interval (CI) 1.526-8.067), P= 0.003], pregnancy-induced hypertensive disorders [AOR 2.69; 95% CI (1.351-5.357), P= 0.005], prolonged second stage of labor [AOR 2.63; 95% CI (1.399-4.944), P= 0.003], Cesarean delivery [AOR 2.005; 95%CI (1.223-3.287), P= 0.006],meconium-stained liquor [AOR 6.955; 95% CI (3.721-13.001), P<0.001], and low birth weight [AOR 4.38; 95% CI (2.216-8.657), P<0.001].CONCLUSION: Result from this study showed a remarkable linkage of low Apgar score with antepartum hemorrhage, pregnancy-induced hypertensive disorders, meconium-stained liquor, and low birth weight. Therefore, meticulous antenatal care and labour management service are recommended to prevent low Apgar score and the concomitant neonatal death.


2019 ◽  
Vol 27 (1) ◽  
pp. 12
Author(s):  
Kanda Izzatul Aini Ardelia ◽  
Gatut Hardianto ◽  
Djohar Nuswantoro

Objectives: to analyze the relationship between passive smoker of pregnant women with low birth weight (LBW).Materials and Methods: This study is an observational analytic research with case control design, which is LBW as case group and normal birth weight as control group. The location is in Wonokusumo Health Centre, Surabaya, period January 2016 – December 2017. Study sample was 68, consisting of 34 cases and 34 controls. The dependent variable is LBW, while the inde-pendent variable is passive smoking of pregnant women. Sample was excluded multiple births and congenital defects. To determine a significant level, the data collected will be tested with the statistical test Chi-square at significance level ?=0.05.Results: The results showed that a majority (61.5%) of passive smoker of pregnant women are cases. After Chi-square test obtained by value p=0.027 (p?0,05) and OR analysis obtained by 3.04 (CI 95% 1.117 – 8.274), which means there is a relationship between passive smoker of pregnant women with LBW.Conclusion: Passive smoker of pregnant women is relationship with decreased birth weight.


2019 ◽  
Author(s):  
Firehiwot Tebeje ◽  
Animut Addis ◽  
Muktar Basher ◽  
Chernet Hialu

Abstract Background: Ethiopia meets the target millennium development goal 4 on child survival three years ahead of time. However, there were high perinatal deaths in the country and the reduction was not impressive. Identifying determinants and implement evidence based interventions is crucial to reduce perinatal death. However, there were no clear evidences on determinants of perinatal mortality in Tercha General Hospital.Objective: To assess determinants of perinatal mortality in Tercha general hospital, Southern Ethiopia, January 1, 2014 and December 30, 2017.Method: An unmatched case control study using secondary data as a source of information was conducted in Tercha general hospital. Cases were stillbirths and early neonatal deaths. Controls were those newborns live till 7th days. Randomly selected 366 (183 cases and 183 controls) study subjects were constituted for this study. The data were collected from March 1-20/2018. Epi-Data version 3.1 and SPSS Version 23 were used for data entry and analysis, respectively. Descriptive statistics were used to describe the study population in relation to study variables. Logistic regressions were employed to identify determinants of perinatal death.Results: In multivariable logistic analysis, rural in residence of the mother [AOR=1.82; 95%CI:(1.04-3.19)], ANC booking [AOR=0.47; 95%CI:(0.27,0.83)], prolonged labour [AOR=2.75; 95%CI: (1.58-4.78)], low birth weight [AOR=1.78; 95%CI (1.06-2.97)], presence of obstetrics complication [AOR=2.15; 95%CI: (1.28-3.62)], using partograph [AOR=0.5; 95%CI: 0.25-0.9]. Using safe child birth checklist [AOR=0.52; 95%CI: 0.30-0.91], and coming with referral [(AOR=2.69; 95% CI: (1.51-4.8)] were significantly associated with perinatal mortality. Conclusion and Recommendation: Being rural in residence, coming with referral, low birth weight, prolonged labour and presence of obstetric complication were associated with elevated the risk of perinatal mortality, and antenatal care booking, using partograph and using safe childbirthchecklist were associated with reduced risk of perinatal mortality. We therefore, recommend strengthening maternal health and newborn care servicesby taking into account these factors to reduce perinatal death.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mesfin Tadese ◽  
Abdulwahhab Seid Minhaji ◽  
Chalachew Tegegne Mengist ◽  
Fetene Kasahun ◽  
Getaneh Baye Mulu

Abstract Background Low birth weight is weight less than 2500 g or 5.5 lb. at birth. Globally, more than 20 million infants (15-20%) are born with a low birth weight each year. Birth weight is the primary indicator of the health status of neonates and is the primary factor that determines the infant’s physical, survival, and mental growth. Thus, the study aimed to investigate the determinants of low birth weight among newborn babies delivered at Tirunesh Beijing General Hospital, Addis Ababa, Ethiopia. Methods We performed a facility-based unmatched case-control study among 453 (151 cases and 302 controls) deliveries conducted at Tirunesh Beijing General Hospital. Birth records and maternal antenatal care (ANC) files were reviewed from March 1 to April 30, 2019. Consecutive sampling was employed to select study participants. Data were entered into Epi-data version 4.2.1 and analyzed using SPSS version 25 statistical software. Descriptive statistics and logistic regression analysis were computed to identify independent determinants of low birth weight. A p-value of ≤0.05 was used to declare statistical significance. Result Four hundred fifty-three birth records of babies (151 cases and 302 controls) were reviewed. Women who reside in rural area [AOR (CI) = 3.12 (1.63-5.98)], being merchant [(AOR (CI) = 2.90 (1.03-8.22)], danger sign during pregnancy [(AOR (CI) = 4.14 (1.68-10.2)], and maternal weight during pregnancy [(AOR (CI) = 4.94 (3.26-7.52)] were found to be a significant determinants of low birth weight. Conclusion Residence, occupation, danger signs, and maternal weight during pregnancy were significant determinants of low birth weight. Socioeconomic development, early detection and management of complications, and encouraging nutrition and weight during pregnancy are crucial for minimizing the risk of delivering low birth weight babies.


2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Yulia Efni ◽  
Rizanda Machmud ◽  
Dian Pertiwi

AbstrakAda beberapa faktor risiko yang meningkatkan angka kejadian pneumonia di negara berkembang yaitu: kurangnya pemberian Air Susu Ibu (ASI) eksklusif, gizi buruk, polusi udara dalam ruangan, Bayi Berat Lahir Rendah (BBLR) dan kurangnya imunisasi campak. Tujuan penelitian ini adalah menentukan faktor risiko yang berhubungan dengan kejadian pneumonia pada balita di Kelurahan Air Tawar Barat, Kota Padang. Penelitian ini menggunakan desain case control study, sampel terdiri dari 27 case dan 27 control. Data dikumpulkan dengan wawancara terpimpin serta melihat data rekam medik dan dianalisis dengan uji chi-square. Hasil penelitian  mendapatkan balita pada kelompok kasus yang tidak mendapatkan ASI eksklusif (81,5%), paparan asap rokok (74,1%), riwayat bayi berat lahir rendah (3,7%), tidak mendapatkan imunisasi campak (40,7%) dan gizi kurang (25,9%). Hasil analisis bivariat menunjukkan terdapat hubungan yang bermakna antara status gizi dengan kejadian pneumonia (p=0,022; OR=9,1; 95%CI=1,034-80,089), sedangkan pemberian ASI eksklusif, paparan asap rokok, riwayat bayi berat lahir rendah dan imunisasi campak tidak terdapat hubungan yang bermakna terhadap pneumonia.Kata kunci: balita, faktor risiko, pneumonia AbstractPneumonia in developing countries are associated to the risk factors such as: lack of exclusive breastfeeding, malnutrition, indoor air pollution, low birth weight and lack of measles vaccinations. The objective of this study was to determine the risk factors associated on the occurrence of pneumonia among the children under five years of age in Air Tawar Barat district, Padang City. This study used case control study  to the 27 cases and 27 control. The data were collected by guided interview and the medical records, than was analyzed by chi-square.test. The results of this study obtanined in the group of cases based on the low exclusive breastfeeding rates (81.5%), exposure to cigarette smoke (74.1%), a history of low birth weight (3.7%), did not get measles vaccinations (40.7%) and malnutrition (25.9%). The result of bivariate analysis shows the significant relationship between nutritional status on the occurrence of pneumonia (p=0.022; OR=9.1; 95% CI=1.034-80.089). The exclusive breastfeeding, exposure to cigarette smoke, a history of low birth weight and measles vaccinations are not significantly related to the occurrence of pneumonia. Keywords: children under five years of age, risk factors, pneumonia


PEDIATRICS ◽  
1988 ◽  
Vol 81 (6) ◽  
pp. 807-811
Author(s):  
C. G. Victora ◽  
P. G. Smith ◽  
J. P. Vaughan ◽  
L. C. Nobre ◽  
C. Lombardi ◽  
...  

The association between birth weight and infant mortality from infectious diseases was investigated in a population-based case-control study in two urban areas in southern Brazil. All deaths of children, seven to 364 days of age, occurring in a year were studied and the parents of the 357 infants dying of an infectious cause were interviewed, as were the parents of two neighborhood control infants for each case. Low birth weight infants (&lt;2,500 g) were found, after allowing for confounding factors, to be 2.3 (90% confidence interval = 1.6 to 3.4) times more likely to die of an infection than those of higher birth weight. The odds ratios were 2.0 (1.1 to 3.6) for deaths due to diarrhea, 1.9 (1.0 to 3.6) for respiratory infections, and 5.0 (1.3 to 18.6) for other infections. These estimates of the risks associated with low birth weight are considerably lower than those from studies in developed countries.


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