Study of the neonatal outcomes in babies born to elderly mothers and young mothers

Background: More and more women are focusing on obtaining higher education and reaching career objectives. This has in turn, lead to delayed marriage and child birth at a later age. Advanced maternal age at birth has been found to be associated with preterm delivery, low birth weight, intrauterine fetal death and increased perinatal morbidity and mortality. The aim of our study was to know the neonatal outcome in elderly mothers and young mothers, and to compare the neonatal outcome of these two groups. Methods: Present study was a cross sectional, analytical case control study, done in babies delivered to mothers >35 years and <35 years. Information like period of gestation, birth weight, APGAR at 1 minute and 5 minutes, NICU admissions, neonatal outcome like respiratory distress, jaundice, convulsion, etc. were recorded in a proforma. Collected data was analysed using appropriate statistical tests.Results: In the present study, total sample size was 460 (230 cases and 230 controls). Incidence of preterm deliveries, Low birth weight, NICU admissions were significantly more in case group (babies born to mothers >35 years) than the control group (babies born to mothers between 19 to 35 years).Conclusions: It was observed that low birth weight, prematurity and NICU admissions were more common in babies born to elderly mothers.

Download Full-text

Determination of the Effect of High-Dose Intralipid in Compared to Its Gradual Dose in Very Low Birth Weight Newborns: A Case-control Study

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2019/v30i230267 ◽

2019 ◽

pp. 1-7

Author(s):

Mandana Kashaki ◽

Arash Bordbar ◽

Ali Mazouri ◽

Nikta Nikbakht ◽

Babak Jafarvand

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Case Control Study ◽

Very Low Birth Weight ◽

Control Group ◽

P Value ◽

Case Group ◽

High Dose ◽

Control Study ◽

Gradual Dose

Objective: The aim of this study was to determine the effect of high dose intralipid in compared to its gradual dose in very low birth weight newborns in Iran. Methods: This study was a case-control study that conducted on 104 very low birth weight infants (<1500 g) referred to Akbarabadi hospital of Tehran (Iran) in 2016. The infants were randomly assigned to two groups (case group: 52 vs. control group: 52). The control group received intralipid 20% with a dose of 1 g/kg/24 h in the first and second day of the study, then from 3rd day to 3 g/kg /24h was raised. But, the case group received 3 g/kg/24 h of intralipid 20% from the first day and continued until the end of the study. In both groups, the study lasted for up to 30 days. Data were collected and analyzed using SPSS22 software. Also P-Value <0.05 was considered as a significant level. Results: The results showed mean daily weight gain in case group is higher than control group and this difference was significant statistically (P-Value < 0.05). Also, although the mean of blood sugar, triglyceride, HCO3, the number of positive blood culture and the number of positive CPR in case group were higher than control group, but these differences were not statistically significant (P-Value >0.05). Conclusion: Given that the better and faster growth of newborns in the intralipid group with high-dose in compared to intralipid group with gradual dose, the use of higher initial doses is recommended in newborns with very low birth weight.

Download Full-text

Host factors related to pneumonia in children under 5 years of age

Paediatrica Indonesiana ◽

10.14238/pi55.5.2015.248-51 ◽

2015 ◽

Vol 55 (5) ◽

pp. 248 ◽

Cited By ~ 1

Author(s):

Wiharjo Hadisuwarno ◽

Retno Asih Setyoningrum ◽

Pirlina Umiastuti

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

General Hospital ◽

Exclusive Breastfeeding ◽

Respiratory Infections ◽

Host Factors ◽

Control Group ◽

Case Group ◽

Control Study ◽

Children Under 5

Background Pneumonia has been one of the serious problems for children under five in Indonesia. Imbalanced interactions among host factors, agents, and environments influence incidence of pneumonia. Objective To determine the risks of the host related to the incidence of pneumonia in children aged 3-59 months in Pediatrics Department, Dr. Soetomo General Hospital during 2011-2012. Methods This was a case control study on medical records of patients with respiratory infections in Pediatrics Department, Dr. Soetomo General Hospital. We grouped patients with pneumonia as the case group and patients with other respiratory infections as the control group. The data were statistically processed to calculate odds ratios and P values. Results There were 326 subjects reviewed, 163 in the case group and 163 in the control group. Host factors that increased the risk of pneumonia were: low birth weight (OR=3.10; 95%CI 1.34 to 6.86), inadequate exclusive breastfeeding (OR=1.7; 95%CI 1.09 to 2.64), malnutrition (OR=3.44; 95%CI 2.12 to 5.58) and incomplete immunization in a certain period of age (OR=2.70; 95%CI 1.72 to 4.24). Existed comorbidity was unrelated to the incidence of pneumonia (OR=1.53; 95%CI 0.86 to 2.71). Conclusion Low birth weight, inadequate exclusive breastfeeding, malnutrition, and incomplete immunization in a certain period of age increase the risk of pneumonia.

Download Full-text

Effect of adolescent pregnancy on the incidence of low birthweight in Dr Soetomo Hospital, Surabaya, Indonesia

Majalah Obstetri & Ginekologi ◽

10.20473/mog.v28i22020.67-74 ◽

2020 ◽

Vol 28 (2) ◽

pp. 67

Author(s):

Nur Lailatul Fadhilah ◽

Rizky Pranadyan

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Adolescent Pregnancy ◽

Low Birthweight ◽

Neonatal Outcome ◽

Total Sample ◽

Cross Sectional Study ◽

P Value ◽

Chi Square ◽

Cross Sectional

Objective: The aim of this study to analyze correlation of neonatal outcome in adolescent pregnancy in Soetomo Hospital within 2014-2017.Materials and Methods: This study was analytic observational cross-sectional study using medical record period 2014-2017 in Obstetric and Gynecology Department, Faculty of Medicine of Airlangga University by using total sampling.Results: The number of total sample among all adolescent pregnancy during 4 years was 184 patient (3,2%) of 5770 patient. The neonatal outcome among all of them were low birth weight, 184 cases (7,8%) of 2350 cases were LBW. 19 cases (5,7%) of 329 cases in percentile <10. This data was analyzed by chi-square SPSS with p value 0,218 (p>0,05), means there were no significant correlation.Conclusion: Adolescent pregnancy had no correlation with low birth weight in neonatal outcome.

Download Full-text

High Blood Pressure during Pregnancy is not a Protective Factor for Preterm Infants with Very Low Birth Weight. A Case-Control Study

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0037-1601883 ◽

2017 ◽

Vol 39 (04) ◽

pp. 155-161 ◽

Cited By ~ 1

Author(s):

Annibal Sabino ◽

Eduardo de Souza ◽

Ana Goulart ◽

Adriana Lima ◽

Nelson Sass

Keyword(s):

Blood Pressure ◽

Birth Weight ◽

Low Birth Weight ◽

Protective Factor ◽

Case Control Study ◽

Very Low Birth Weight ◽

Case Control ◽

World Health ◽

Control Group ◽

Control Study

Objective To evaluate whether the presence of maternal blood pressure reduces the risks of morbidity, perinatal mortality and morbidity at 24 months of age in very low birth weight infants (VLBWIs) compared with a control group. Methods A retrospective, observational, case-control study. Total 49 VLBWIs were allocated to the study group, called the maternal arterial hypertension group (AHG), and matched with 44 in the control group (CG). The infants were assessed during hospitalization and at 12 and 24 months corrected age at a specialized clinic. For the assessment of growth, the World Health Organization (WHO) Anthro software (Geneva, 2006) was used, and for the psychomotor assessment, the Denver II test was used. Results In relation to the antenatal variables, the infants of the AHG had more centralized circulation assessed by Doppler, received more corticosteroids and magnesium sulfate, and were born by cesarean section more frequently. In terms of the postnatal and in-hospital outcomes, the AHG had a higher gestational age at birth (30.7 versus 29.6 weeks) and a lower frequency of 5-minute Apgar scores of less than 7 (26.5% versus 52.3%). The CG had a higher rate of pulmonary dysplasia (30.2% versus 8.3%). There were no differences in terms of hospital mortality, complications, somatic growth and functional problems at 24 months of corrected age. Conclusion The presence of maternal hypertension, especially preeclampsia, was not a protective factor against morbidity, mortality and evolution in VLBWIs aged up to 24 months. Therefore, the clinical practice should be focused on prolonging the pregnancy for as long as possible in these conditions as well.

Download Full-text

Passive smoker during pregnancy is a risk factor of low birth weight

Majalah Obstetri & Ginekologi ◽

10.20473/mog.v1i12019.12-16 ◽

2019 ◽

Vol 27 (1) ◽

pp. 12

Author(s):

Kanda Izzatul Aini Ardelia ◽

Gatut Hardianto ◽

Djohar Nuswantoro

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Pregnant Women ◽

Health Centre ◽

Congenital Defects ◽

Control Group ◽

Case Group ◽

Chi Square ◽

Significance Level ◽

Passive Smoker

Objectives: to analyze the relationship between passive smoker of pregnant women with low birth weight (LBW).Materials and Methods: This study is an observational analytic research with case control design, which is LBW as case group and normal birth weight as control group. The location is in Wonokusumo Health Centre, Surabaya, period January 2016 – December 2017. Study sample was 68, consisting of 34 cases and 34 controls. The dependent variable is LBW, while the inde-pendent variable is passive smoking of pregnant women. Sample was excluded multiple births and congenital defects. To determine a significant level, the data collected will be tested with the statistical test Chi-square at significance level ?=0.05.Results: The results showed that a majority (61.5%) of passive smoker of pregnant women are cases. After Chi-square test obtained by value p=0.027 (p?0,05) and OR analysis obtained by 3.04 (CI 95% 1.117 – 8.274), which means there is a relationship between passive smoker of pregnant women with LBW.Conclusion: Passive smoker of pregnant women is relationship with decreased birth weight.

Download Full-text

THE ANALYSIS OF LOW BIRTH WEIGHT INFANTS IN SINGKAWANG CITY

Jurnal Kesehatan Prima ◽

10.32807/jkp.v12i1.94 ◽

2018 ◽

Vol 12 (1) ◽

pp. 61

Author(s):

U. Evi Nasla Nasla

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Antenatal Care ◽

Total Sample ◽

Low Birth Weight Infants ◽

Chi Square ◽

Cross Sectional ◽

Arm Circumference ◽

Newborn Weight ◽

Chi Square Test

Abstract: The efforts of decreasing the infant mortality is focused on the causes of infant’s death. One of them is the lowest Birth Weight that can be prevented through a quality and comprehensive antenatal care. The factors that affect the occurrence of low birth weight (LBW) in Singkawang city is age, parity, range of pregnancy, arm circumference, antenatal care, anemia history, newborn weight. The objective study was to determine the factors that affect the occurrence of LBW in Singkawang in 2015. This research employed analytical survey research design with retrospectively approach with cross sectional design. The sample used is the case of newborn with LBW as many as 105 with a ratio of 1: 1 with a total sample of 210 babies. The sample was random sampling. The data analysis used Chi Square and logistic regression test. Chi Square test results showed that there was a significant relationship between age, arm circumference, antenatal care of anemia (p = 0.005, p = 0.013, p = 0.020, p = 0.003) with the incidence of LBW. And there was no significant correlation between parity and range of pregnancy (p = 0.805, p = 0.766). This research is expected to be the basis of evaluating the occurrence of LBW thus it can be detected earlier.Keywords: Age; Parity; Antenatal Care; Arm Circumference; Anemia history; Lowest Birt Weight.

Download Full-text

Pregnancy outcome in isolated oligohydramnios diagnosed in third trimester

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211510 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1914

Author(s):

Pratibha Singh ◽

Vibha Rani Pipal ◽

Dharmendra Kumar Pipal ◽

Navdeep Kaur Ghuman ◽

Garima Yadav ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Amniotic Fluid ◽

Pregnancy Outcome ◽

Preterm Delivery ◽

Neonatal Outcome ◽

Low Risk ◽

Control Group ◽

P Value ◽

Third Trimester

Background: The aim of this study was to compare the outcomes of pregnancies complicated by isolated oligohydramnios with the low risk pregnancies with normal amniotic fluid volume.Methods: The present study is a retrospective cohort study of singleton pregnancies diagnosed with Isolated oligohydramnios (AFI≤5) in their third trimester (N=35). Pregnancy outcome was compared with a matched control group of low risk pregnancies with amniotic fluid volume >5 (N=30).Results: The overall incidence of Isolated oligohydramnios was 0.7-0.8%. In oligohydramnios group, significant association were found in null-parity (60% vs 23.33%, p-value<0.005), Fetal growth retardation (25.71% vs 0% p-value<0.02), preterm delivery (22.85% vs 3.33%, p-value 0.025), rate of Induction of labor (40% vs 10%) and cesarean rate for non-reassuring fetal heart rate (20% vs 3.33%, p-value<0.001). Likewise, the incidence of low birth weight was (54.28% vs 13.33%, p-value<0.001) and NICU admissions was (20% vs 0%, p-value<0.01), but there was no difference in Apgar score finding. NICU stay was of short duration and all babies discharged in stable condition, there were no stillbirth or early neonatal death in both groups.Conclusions: Isolated oligohydramnios has an adverse influence on pregnancy and neonatal outcome in the form of FGR, preterm delivery, increased rate of Induction and cesarean section. Despite the high incidence of low birth weight and NICU admissions, the overall early neonatal outcome was similar to the other low risk pregnancies.

Download Full-text

The effects of occupational pollutants on the reproductive health of female informal street traders in Warwick Junction, Durban, South Africa – a cross-sectional study

10.21203/rs.2.12541/v4 ◽

2019 ◽

Author(s):

Sujatha Hariparsad ◽

Rajen Naidoo

Keyword(s):

South Africa ◽

Birth Weight ◽

Low Birth Weight ◽

Total Sample ◽

Daily Basis ◽

Cross Sectional Study ◽

Reproductive Outcomes ◽

Sectional Study ◽

Cross Sectional ◽

Increased Risk

Abstract Background: Informal street traders are exposed on a daily basis to traffic emissions and biomass fuel smoke containing a variety of pollutants. These exposures are likely to place the female traders at increased risk for adverse reproductive outcomes. Aim The aim of this study was to compare the reproductive outcomes among street traders exposed to pollutants from their work-related activities and traders without such exposure. Methods: A cross-sectional study was conducted among 305 female traders selected from exposed and non-exposed areas within the Warwick Junction trading hub, located in Durban, South Africa. Validated reproductive questionnaires and clinical assessments were conducted on all participants. Adverse reproductive outcomes such as low birth weight, spontaneous abortions and infertility were assessed Results: The mean age of the traders was 43.6 years (SD:12.1), mostly single (63%) and worked in trading hub for an average of 14 years. There were 876 pregnancies reported in the total sample. Traders pregnant while working in in this location accounted for 120 pregnancies There was an increased risk of exposed traders having a low birth weight infant as compared to non-exposed traders (OR=3.7; CI: 1.8, 7.6). Exposed traders were also almost 3 times more likely to be infertile as compared to non-exposed traders (OR=2.6; CI: 1.6, 4.3). Conclusions: Working as a street trader may have a causal association with developing adverse reproductive outcomes in females. Recommendations to mitigate adverse exposures have been suggested which include short term safety interventions and better cooking practices and future long term policy interventions.

Download Full-text

Pattern of Electrolyte Abnormalities in Preterm Low Birth Weight Neonates

Journal of Dhaka Medical College ◽

10.3329/jdmc.v29i2.51189 ◽

2021 ◽

Vol 29 (2) ◽

pp. 145-148

Author(s):

Md Saiful Islam ◽

Manisha Banerjee ◽

Tafazzal Hossain Khan ◽

Chandan Kumar Shaha ◽

Md Zahir Uddin ◽

...

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Rural Areas ◽

Neonatal Outcome ◽

Close Monitoring ◽

College Hospital ◽

Cross Sectional ◽

Medical College ◽

Increased Risk ◽

Electrolyte Abnormalities

Prematurity and low birth weight contributes to 27.8% of neonatal deaths in rural areas of Bangladesh. Fluid, electrolyte and metabolic abnormalities are the commonest derangements encountered in preterm infants due to their renal immaturity and relatively immature skin. Premature infant are at increased risk of developing dehydration or overhydration4. Therefore, high index of suspicion, prompt recognition and thorough understanding of common electrolyte abnormalities are necessary to improve neonatal outcome. Appropriate fluid and electrolyte management is essential for better neonatal outcome. Objectives: To identify the serum electrolytes abnormalities in preterm low birth weight neonates. Methodology: It was a cross- sectional study and carried out in the Department of Neonatology, Dhaka Medical College Hospital, Dhaka between January 2017 to August 2017. Information was collected who gave consent and participated in the study willingly. The sample size was 50. Patients admitted in the above mentioned hospital and after meeting the inclusion and exclusion criteria a simple random sampling technique was applied for selecting the study subjects. Results: Fifty preterm LBW neonates fulfilling the inclusion criteria were studied during this study period. Abnormal electrolytes were documented in 20(40%) out of 50 preterm LBW neonates and electrolyte status was normal in 30(60.0%) cases. Of 20 neonates who had abnormal electrolytes, hyperkalemia was the predominant electrolyte abnormality found in 8(16.0%) neonates, hyponatremia was found in 7(14.0%), hypokalemia in 3(6.0%) and hypernatremia 2(4.0%). Conclusion: Electrolyte abnormalities are common in preterm LBW neonates. So, identification of electrolyte abnormalities and proper management of fluid and electrolytes and close monitoring are important. J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 145-148

Download Full-text

The Relationship Between Maternal Periodontal Status of and Preterm and Low Birth Weight Infants in Iran: A Case Control Study

Global Journal of Health Science ◽

10.5539/gjhs.v8n5p184 ◽

2015 ◽

Vol 8 (5) ◽

pp. 184 ◽

Cited By ~ 6

Author(s):

Mohammad Reza Karimi ◽

Jalaleddin H Hamissi ◽

Simin Rafieyan Naeini ◽

Mojgan Karimi

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Periodontal Disease ◽

Case Control Study ◽

Periodontal Diseases ◽

Case Control ◽

Control Group ◽

Low Birth Weight Infants ◽

Sample Group ◽

Control Study

AIM & BACKGROUND: It has been suggested that periodontitis is associated with systemic alterations such as adverse pregnancy outcomes. However, some conflicting results have been reported. This study was conducted to determine the association between periodontitis and preterm birth (PTB), low birth weight (LBW) to obtain information which is necessary for the planning of preventive programs of periodontal disease for pregnant women in this area. MATERIALS & METHODS: This case-control study was performed on 264 mothers. The index used to determine oral hygiene and periodontal diseases is Community Periodontal Index Treatment Needs (CPITN). RESULTS: The mothers in the sample group with single delivery delivered 8 times low birth weight infants more than the mothers in the control group with single delivery. And also the mothers in the sample group with multiple deliveries; delivered 10 times low birth weight infants and 8 times premature infant more than the mothers in the control group. CONCLUSION: More studies should be carried out in through preventing and treating periodontal diseases, expenses incurred due to preterm labor and low birth weight decrease and the society will witness fewer mental problems suffered by such children as they grow up. So we can emphasize the importance of periodontal care in prenatal health programs. And we may suggest that a special program of periodontal disease prevention for pregnant women is very necessary.

Download Full-text