scholarly journals COMPARATIVE PHYTOCHEMICAL STUDY OF THE AERIAL PARTS OF THE WILD-GROWING AND CULTIVAT-ED CHICORY ORDINARY (CICHORIUM INTYBUS L.)

2020 ◽  
pp. 187-195
Author(s):  
Ol'ga Leonidovna Saybel ◽  
Andrey Ivanovich Radimich ◽  
Grigoriy Vasil'yevich Adamov ◽  
Tamara Darizhapovna Dargaeva
Keyword(s):  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Scientific Research ◽  
Cichorium Intybus ◽  
Biologically Active ◽  
Qualitative Composition ◽  
Dominant Group ◽  
Phytochemical Study ◽  
Aerial Parts ◽  
In The Wild

The search for new plant species that are promising for use as a source of biologically active substances is an actual area of scientific research in the field of chemistry of natural compounds. The object of this study is the chicory (Cichorium intybus L.) The purpose of our scientific research is to conduct a comparative phytochemical study of the aerial parts of wild-growing and cultivated chicory to establish differences in the qualitative composition and content of secondary metabolites. As a result of studies by HPLC-MS, in the aerial part of a wild-growing plant, 10 compounds were identified esculletin, chicoriin, chicoric acid, chlorogenic acid, kaftaric acid, isochlorogenic A acid, caffeic acid, isoquercetin, astragalin, rutin. The dominant group of substances are oxycoumarins. The phenolic complex of the cultivated plant has a similar composition of secondary metabolites, however, its derivatives are hydroxycinnamic acid derivatives. The quantitative content of phenolic compounds in the wild-growing chicory herb was 2.56±0.12%, cultivated – 4.14±0.21%. Significant differences in the content and qualitative composition of phenolic compounds make it possible to use the chicory of a wild-growing and cultivated population to obtain pharmaceutical substances with various pharmacological effects.

scholarly journals Solvent extraction and spectroscopy identification of bioactive compounds from medicinal shrub Tamarix gallica

2020 ◽  
Vol 10 (11) ◽  
pp. 456
Author(s):  
Moussa Mohammed Elamin
Keyword(s):  
Solvent Extraction ◽  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Bioactive Compounds ◽  
Liquid Extraction ◽  
Spectroscopy Analysis ◽  
Phytochemical Study ◽  
Liquid Liquid Extraction ◽  
Tamarix Gallica

This research is interested in chemical valorization of the medicinal shrub called Tamarix gallica. The phytochemical study of the extracts of this plant showed that it is rich in phenolic compounds especially the flavonoids. The liquid-liquid extraction by n-butanol and acetate of ethyl of the leaves allowed to us the extraction of the secondary metabolites of class of the flavonoids.The identification of the isolated flavonoids is made by the spectroscopy methods: UV, IR, NMRH, from where we extracted some structures of flavonols class. Keywords: Tamarix gallica, chemical valorization, flavonoids, extraction, spectroscopy analysis, chromatography methods.

scholarly journals The study of the qualitative composition and the quantitative content of phenolic compounds in dietary supplements with lingonberry

2021 ◽  
Vol 19 (4(76)) ◽  
pp. 40-46
Author(s):  
Oleksandr Yu. Maslov ◽  
Mykola A. Komisarenko ◽  
Serhii V. Kolisnyk ◽  
Olga V. Antonenko ◽  
Olena V. Kolisnyk ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Dietary Supplements ◽  
Total Content ◽  
Hydroxycinnamic Acids ◽  
Biologically Active ◽  
Qualitative Composition ◽  
Relevant Today ◽  
Quantitative Content ◽  
Layer Chromatography

Aim. Today, there are a lot of dietary supplements with lingonberry at the pharmaceutical market of Ukraine; therefore, the analysis and quality control of these products are relevant. In this connection, the aim of the research was to study the qualitative composition and determine the quantitative content of phenolic compounds in dietary supplements with lingonberry.Materials and methods. Such dietary supplements as “Extract of lingonberry” (MEDAGROPROM), “Lingonberry” (Danikafarm), “Lingonberry nano” (LSS SYSTEM) were chosen for the study. The qualitative analysis was performed by thin layer chromatography (TLC), spectrophotometry was used for the quantitative determination.Results and discussion. Hydroquinone derivatives, flavonoids and hydroxycinnamic acids were found in the dietary supplements analyzed. The total content of phenolic compounds was 8.70, 0.26, 0.30 %, flavonoids – 6.37, 0.15, 0.12 %, hydroxycinnamic acids – 0.94, 0.06, 0.13 %, and hydroquinone derivatives – 1.01, 0.04, 0.03 % in such dietary supplements as “Extract of lingonberry” (MEDAGROPROM), “Lingonberry” (Danikafarm), “Lingonberry nano” (LSS SYSTEM), respectively. Conclusions. The qualitative and quantitative analysis of the dietary supplements with lingonberry analyzed has been performed. “Extract of lingonberry” (MEDAGROPROM) dietary supplement meets the requirements of the State of Pharmacopoeia of Ukraine 2.0, whereas “Lingonberry” (Danikafarm) and “Lingonberry nano” (LSS SYSTEM) do not. Based on the results of the study it can be concluded that the problem of compliance of dietary supplements is relevant today and requires the introduction of regulatory documentation for the detection and determination of biologically active substances in dietary supplements.

scholarly journals Do Compositions of Lipid Fraction Correspond to Species Differentiation in Bupleurum L. (Apiaceae)?

Plants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1407
Author(s):  
Zhargal Alexandrovich Tykheev ◽  
Oleg Arnoldovich Anenkhonov ◽  
Svetlana Vasilievna Zhigzhitzhapova ◽  
Vasiliy Vladimirovich Taraskin ◽  
Larisa Dorzhievna Radnaeva ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Prognostic Value ◽  
Lipid Fraction ◽  
Species Differentiation ◽  
Qualitative Composition ◽  
Medical Systems ◽  
Phytochemical Study ◽  
Similar Composition ◽  
Aerial Parts ◽  
Wide Range

Bupleurum L. has been widely used in various medical systems as an agent with a wide range of activities. The qualitative composition and content of lipid fraction components of the aerial parts of B. longifolium and B. chinense were elucidated in this work. The available data on the fatty acids (FAs) in Bupleurum plants were compiled and compared with species differentiation in the genus. As a result, the content of FAs in the studied Bupleurum plant species only partially corresponded to the species differentiation and, in some cases, contradicted it. The prognostic value of Bupleurum’s species differentiation for the identification of the potential composition of FAs was insignificant, and it was limited only by particular groups of species. This suggests that a complete phytochemical study of Bupleurum species needs to be conducted to determine the composition of FAs and to identify which species have a similar composition.

scholarly journals Flavonoid Glycosides from Endemic Bulgarian Astragalus aitosensis (Ivanisch.)

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1419 ◽  
Author(s):  
Hristo Vasilev ◽  
Samir Ross ◽  
Karel Šmejkal ◽  
Petr Maršík ◽  
Dagmar Jankovská ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Structural Analysis ◽  
Secondary Metabolites ◽  
Chromatographic Separation ◽  
2D Nmr ◽  
Biologically Active ◽  
Spectral Studies ◽  
Flavonoid Glycosides ◽  
Phenolic Components ◽  
First Time

Astragalus is a very interesting plant genus, well-known for its content of flavonoids, triterpenes and polysaccharides. Its secondary metabolites are described as biologically active compounds showing several activities, e.g., immunomodulating, antibacterial, antiviral and hepatoprotective. This inspired us to analyze the Bulgarian endemic A. aitosensis (Ivanisch.) to obtain deeper information about its phenolic components. We used extensive chromatographic separation of A. aitosensis extract to obtain seven phenolic compounds (1–7), which were identified using combined LC-MS and NMR spectral studies. The 1D and 2D NMR analyses and HR-MS allowed us to resolve the structures of known compounds 5–7 as isorhamnetin-3-O-robinobioside, isorhamnetin-3-O-(2,6-di-O-α-rhamno-pyranosyl-β-galactopyranoside), and alangiflavoside, respectively, and further comparison of these spectral data with available literature helped us with structural analysis of newly described flavonoid glycosides 1–4. These were described in plant source for the first time.

scholarly journals The content of phenolic compounds in underground and aerial parts of different Mentha species

2012 ◽  
Vol 59 (1) ◽  
pp. 30-38 ◽  
Author(s):  
S. Fialová ◽  
D. Tekeľová ◽  
D. Grančai
Keyword(s):  
Free Radical ◽  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Spectrophotometric Methods ◽  
The Past ◽  
Aerial Parts ◽  
Hydroxycinnamic Derivatives

The content of phenolic compounds in underground and aerial parts of different Mentha speciesMentha L., the genus belonging to family Lamiaceae, subfamily Nepetoidae, has high commercial importance in the pharmacy as well as in food industry. Mints are available in all five continents and are important sources of each traditional medicine in the prevention and therapy of plenty of diseases. The most active compounds are essential oil and polyphenols. In the past the secondary metabolites in aerial parts were examined, but there is no evidence about the determination of secondary metabolites in underground parts of mints. Therefore the object of this work was to determine the content of phenolic compounds (total hydroxycinnamic derivatives (THD) and flavonoids) of methanol extracts of rhizomes of different Mentha L. and their comparison with leaves extracts. The contents of secondary metabolites were determined using spectrophotometric methods of Slovak Pharmacopoeia. We have detected similar quantities of THD in leaves (0.79 - 2.48 %) and rhizomes (0.96 - 2.18 %), but underground parts were poor in content of flavonoids (< 0.1 %). The free radical scavenging activity using DPPH free radical was investigated as well. A bit stronger antioxidant activity was shown in leaves extracts considering flavonoids content.

scholarly journals PHYTOCHEMICAL STUDY OF ZYGOPHYLLUM ALBUM EXTRACT

2020 ◽  
Vol 4 (5) ◽  
pp. 1-10
Author(s):  
Belmimoun A ◽  
Meddah B ◽  
Side Larbi K ◽  
Sonnet P.
Keyword(s):  
Chemical Composition ◽  
Phenolic Compounds ◽  
Functional Food ◽  
Methanolic Extract ◽  
Folk Medicine ◽  
Extraction Methods ◽  
Phytochemical Study ◽  
Aerial Parts ◽  
Health Products ◽  
Promising Source

The aerial parts of Zygophyllum album L. are used in folk medicine as an anti-diabetic agent and as a drug active against several pathologies. In this work we present the chemical composition of Algerian phenolic extracts obtained by different solvents and extraction methods The phytochemical study was based on a colometer method, Phenolic compound content and LC/ESI-MS analyses The methanolic extract of zygophyllum album was at least the best extract studied for its quantitative and qualitative richness in phenolic compounds All Z.album extracts and specially the methanolic one are a promising source of health products for functional food or nutraceutical industries.

scholarly journals COMPONENTS OF ARTEMISIA SOGDIANA

2020 ◽  
pp. 207-214
Author(s):  
Rimma Fail'yevna Mukhamatkhanova ◽  
Khayrulla Mamadievich Bobakulov ◽  
Il'dar Dzhamil'yevich Sham’yanov ◽  
Rasul Yangiberdievich Оkmanov ◽  
Haji Akber Aisa ◽  
...  
Keyword(s):  
Pharmaceutical Industry ◽  
Secondary Metabolites ◽  
Aerial Part ◽  
Sesquiterpene Lactones ◽  
Biologically Active ◽  
Phytochemical Study ◽  
Alcohol Extract ◽  
Effective Use ◽  
Medicinal Flora ◽  
First Time

Phytochemical research and effective use of medicinal flora in the future create the basis for the development of the domestic pharmaceutical industry and allow not only to fill the deficit of drugs, but also contribute to the development of new, environmentally friendly and a number of qualities of unique, export-oriented preparations. The plants of the genus Artemisia L. are rich sources of biologically active secondary metabolites. Phytochemical study of secondary metabolites of plants of the genus Artemisia has led to the creation on their basis, in particular, on the sesquiterpene lactones, antitumor (Artemisinin and its derivatives; Arglabin), antiatherosclerotic (Leucomisin (preparation Oligvon)), cardiotonic (Tauremisin), anthelmintic (α-Santonin) and antimalarial (Artemisinin and its derivatives) preparations. In order to search for natural biologically active compounds, we studied the components of the alcohol extract of the aerial part of Artemisia sogdiana Bunge, collected during budding in the Zaamin district of the Jizzakh region of Uzbekistan. The result of phytochemical research for the first time from this plant is isolated a phenolic compound xanthoxylin, sesquiterpene lactone artesin, flavonoids genkwanin and eupatilin, the structure of which is established on the basis of spectral data.

scholarly journals Qualitative and quantitative analysis of the content of phenolic compounds and their derivatives in the rhizome of Panax vietnamensis Ha et Grushv

2019 ◽  
Vol 58 (5) ◽  
pp. 39-43
Author(s):  
Roman O. Grigoryev ◽  
◽  
Nadezhda K, Chirikova ◽  
Daniil N. Olennikov ◽  
◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Secondary Metabolites ◽  
Folk Medicine ◽  
Population Based ◽  
Consumer Products ◽  
Biologically Active ◽  
Wide Range ◽  
Ancient Times ◽  
Unique Composition

Since ancient times, it is known that all types of ginseng were widely used in Eastern folk medicine as a cure for many diseases. All species of the genus Panax, including Panax vietnamensis, contain saponins, but the phenolic composition has not been studied to date. Vietnamese ginseng is characterized by a unique composition of triterpene glycosides, among which the glycosylated derivatives of the rare triterpene aglycone, okothylol, are predominant. It is the only evergreen among ginsengs. As you know, a single plant can have different types of biological activity due to the content of different groups of biologically active compounds with a wide range of physicochemical properties and causing different pharmacological effects. Obviously, phenolic compounds along with other secondary metabolites in Panax vietnamensis have a phytotherapeutic effect on the human body. The purpose of this work is to expand the knowledge of the scientific community about the synthesized compounds, in particular about phenolic compounds that accumulate in the rhizomes of Panax vietnamensis. In this paper, the results of a study on the qualitative (method HPLC-DMD-MS) and quantitative content of phenolic compounds (Folin-Cicalteu method) of the roots of Panax vietnamensis were presented for the first time. These results can be very interesting for scientists involved in the synthesis of secondary metabolites, growing callus and suspension cell cultures in vitro ginseng and other ginseng species, as well as for pharmaceutical and cosmetic companies producing various consumer products for the population based on Vietnamese ginseng. This work will expand the scientific community’s knowledge of secondary metabolites synthesized by the rhizome Panax vietnamensis Ha et Grushv.

scholarly journals Phytochemical study of the genus amphoricarpos

2021 ◽  
pp. 83-83
Author(s):  
Iris Djordjevic ◽  
Mirjana Cvetkovic ◽  
Milka Jadranin ◽  
Srdjan Bojovic ◽  
Boban Andjelkovic ◽  
...  
Keyword(s):  
Organic Chemistry ◽  
Herbal Medicine ◽  
Secondary Metabolites ◽  
Folk Medicine ◽  
Plant Diseases ◽  
Biologically Active ◽  
Early 20Th Century ◽  
Isolation And Identification ◽  
Plant Adaptation ◽  
Phytochemical Study

Phytochemistry deals with the study of secondary metabolites produced by plants that synthesize these compounds for many reasons, including their own protection against attack of herbivores and plant diseases. Secondary metabolites are believed to represent plant adaptation to various environmental factors and that they enabled the survival of the species. Secondary metabolites of plants can have curative or toxic effects in humans and animals. Herbal medicine has a long tradition in folk medicine and until the early 20th century, when synthetic organic chemistry began to develop, plants were the main source of medicines. Basic goals of our phytochemical research include the following: isolation and identification of new (biologically active) compounds - potential drugs, and chemotaxonomy (chemosystematics). In the following text through one selected example - genus Amphoricarpos Vis. - both aspects of our phytochemical research are shown.

Sign in / Sign up

Export Citation Format

Share Document