scholarly journals Biosafety of Nanoparticles Used in Orthodontics - A Literature Review

2021 ◽  
Vol 10 (32) ◽  
pp. 2658-2664
Author(s):  
Nausheen Mobeen ◽  
Shreya Kishore ◽  
Rasiga Gandhi ◽  
Sangeetha Duraisamy ◽  
Ravi K.
Keyword(s):  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Tissue Response ◽  
Orthodontic Wires ◽  
Biological Safety ◽  
Nanosized Materials ◽  
Regulatory Standards ◽  
Scientific Potential ◽  
Orthodontic Materials ◽  
Adequate Tissue

Nanotechnology is the science of manipulating matter, measured in the billionths of a nanometer, roughly the size of two or three atoms. It is widely used in our day-today life including its use in medicine and is considered as a vital current technology of the 21st century based on its economic and scientific potential. Its application is being experimented in various domains in orthodontics, from surface coatings to the development of novel materials. Orthodontic materials must have specific characteristics such as biological safety, functionality, and adequate tissue response. They have to pass specific biocompatibility tests to meet regulatory standards. Any material used in oral cavity might encourage unnecessary disturbance due to its complex and varied environment. The nanomaterials have many advantages in the field of orthodontics, especially with improved mechanical and antimicrobial properties. Nanoparticles can easily penetrate tissues and can affect biological behaviours at different levels. The introduction of nanotechnology gives better opportunities to both patient and orthodontist to new physicochemical, mechanical, and antibacterial properties of nanosized materials and can be used in coating orthodontic wires, elastomeric ligatures, and brackets, producing shape memory polymers and orthodontic bonding materials. The present review article focuses on the application of nanoparticles in orthodontics. This article presents a brief overview of nanotechnology, types of nanoparticles, biological safety of different nanoparticles used in orthodontics and their applications in the field of dentistry and orthodontics. KEY WORDS Nanoparticles, Biocompatibility, Orthodontics, Nanoscience

scholarly journals Evaluating the Antimicrobial Activity of Commercially Available Herbal Toothpastes on Microorganisms Associated with Diabetes Mellitus

2013 ◽  
Vol 14 (5) ◽  
pp. 924-929 ◽  
Author(s):  
Reena Kulshrestha ◽  
J Kranthi ◽  
P Krishna Rao ◽  
Feroz Jenner ◽  
V Abdul Jaleel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Antimicrobial Activity ◽  
Dental Health ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Test Organism ◽  
Diffusion Method ◽  
Zone Of Inhibition ◽  
Disk Diffusion Method

ABSTRACT Aim The present study was conducted to evaluate the efficacy of commercially available herbal toothpastes against the different periodontopathogens. Materials and methods Six herbal toothpastes that were commonly commercially available were included in the study. Colgate herbal, Babool, Meswak, Neem active, Dabur red toothpastes were tested for the study whereas sterile normal saline was used as control. Antimicrobial efficacies of dentifrices were evaluated against Streptococcus mutans and Actinobacillus actinomycetemcomitans. The antimicrobial properties of dentifrices were tested by measuring the maximum zone of inhibition at 24 hours on the Mueller Hinton Agar media inoculated with microbial strain using disk diffusion method. Each dentifrice was tested at 100% concentration (full strength). Results The study showed that all dentifrices selected for the study were effective against the entire test organism but to varying degree. Neem active tooth paste gave a reading of 25.4 mm as the zone of inhibition which was highest amongst all of the test dentifrices. Colgate Herbal and Meswak dentifrices recorded a larger maximum zone of inhibition, measuring 23 and 22.6 mm respectively, compared to other toothpastes. All other dentifrices showed the zone of inhibition to be between 17 and 19 mm respectively. Conclusion The antibacterial properties of six dentifrices were studied in vitro and concluded that almost all of the dentifrices available commercially had antibacterial properties to some extent to benefit dental health or antiplaque action. How to cite this article Jenner F, Jaleel VA, Kulshrestha R, Maheswar G, Rao PK, Kranthi J. Evaluating the Antimicrobial Activity of Commercially Available Herbal Toothpastes on Microorganisms Associated with Diabetes Mellitus. J Contemp Dent Pract 2013;14(5):924-929.

scholarly journals Production and Characterization of Keratin/Tragacanth Gum Nanohydrogels for Drug Delivery in Medical Textiles

2021 ◽  
Vol 8 ◽  
Author(s):  
Nazanin Mansouri Shirazi ◽  
Niloofar Eslahi ◽  
Adeleh Gholipour-Kanani
Keyword(s):  
Disulfide Bonds ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Spherical Shape ◽  
Herbal Extract ◽  
Minimum Size ◽  
Mechanical Resistance ◽  
Tragacanth Gum ◽  
Medical Textiles

Keratin protein has been applied for biomedical applications due to its biocompatibility, biodegradability, mechanical resistance, and bioavailability. Tragacanth gum (TG) as a polysaccharide-based biopolymer has wound healing and antimicrobial properties. In this study, keratin was extracted from protein-based chicken feather by using reduction hydrolysis (sodium sulfide), and nanogels of keratin and TG composites at different ratios were produced by using the chemical cross-linking method. Then, cinnamon (5 and 10%) as an antibacterial herbal extract was added to the nanogels and coated on cotton fabric. The morphology and size of the composite nanogels, chemical structure, biological, and antibacterial properties were evaluated. According to DLS results, TGK2:1 (ratio of TG to keratin = 2:1) had the minimum size (80 nm) and PDI (0.1), and therefore, this sample was chosen as the optimum one. FESEM and TEM images showed the semi-spherical shape of the produced nanogels. FTIR spectra revealed the possible hydrogen bonding between the components, and the formation of disulfide bonds after the addition of hydrogen peroxide was confirmed by XPS. After loading cinnamon into the nanogels, an increase in size was observed from 80 nm for free-nanogel to 85 and 105 nm for 5 and 10% extract-loaded nanogels, respectively. Besides, more cinnamon was released from the treated fabrics by increasing time and cinnamon concentration. The antibacterial test exhibited good antibacterial properties against both Gram-positive and Gram-negative bacteria. Finally, MTT assay approved the biocompatibility of the produced nanogels for potential use in medical textiles.

Barrier and Antibacterial Properties of 2-Octyl Cyanoacrylate-Derived Wound Treatment Films

2003 ◽  
Vol 7 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Patricia M. Mertz ◽  
Stephen C. Davis ◽  
Alejandro L. Cazzaniga ◽  
Anna Drosou ◽  
William H. Eaglstein
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Bacterial Contamination ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Bacterial Invasion ◽  
Wound Treatment ◽  
Antimicrobial Study ◽  
And Control ◽  
Number Of Bacteria

Background: Besides enhancing healing, an ideal dressing should prevent invasion of pathogens and control the number of bacteria already present in the wounds. Objective: To evaluate the barrier and antimicrobial properties of a cyanoacrylate-based bandage (LAB) against Staphylococcus aureus or Pseudomonas aeruginosa on partial thickness wounds in swines. Methods: Barrier study: Bacteria were inoculated over test materials (LAB, standard bandage, air-exposed) that were placed over wounds. The bacteria from wounds were quantitated at 24, 48, and 72 hours postinoculation. Antimicrobial study: Wounds inoculated with bacteria were covered with LAB, standard bandage, or hydrocolloid bandage or left air-exposed. The bacteria recovered from wounds were quantitated at 24 and 72 hours after treatment. Results: Barrier study: No bacteria were recovered from LAB-treated wounds. Antimicrobial study: LAB reduced the number of inoculated bacteria in comparison to all other groups. Conclusion: LAB is effective in protecting wounds from external bacterial invasion and reducing bacterial contamination.

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

scholarly journals Surface Modification of Orthodontic Wires with Photocatalytic Titanium Oxide for its Antiadherent and Antibacterial Properties

2007 ◽  
Vol 77 (3) ◽  
pp. 483-488 ◽  
Author(s):  
Mi-Jin Chun ◽  
Eunju Shim ◽  
Eun-Hee Kho ◽  
Keum-Joo Park ◽  
Jarang Jung ◽  
...  
Keyword(s):  
Surface Modification ◽  
Titanium Oxide ◽  
Antibacterial Properties ◽  
Orthodontic Wires

scholarly journals Antibacterial properties of electrospun Ti3C2Tz(MXene)/chitosan nanofibers

RSC Advances ◽  
2018 ◽  
Vol 8 (62) ◽  
pp. 35386-35394 ◽  
Author(s):  
Elisa A. Mayerberger ◽  
Reva M. Street ◽  
Riki M. McDaniel ◽  
Michel W. Barsoum ◽  
Caroline L. Schauer
Keyword(s):  
Low Cost ◽  
Antibacterial Properties ◽  
Antimicrobial Properties

Electrospun natural polymeric bandages are highly desirable due to their low-cost, biodegradability, non-toxicity and antimicrobial properties.

scholarly journals Zinc(II) Complexes with Amino Acids for Potential Use in Dermatology: Synthesis, Crystal Structures, and Antibacterial Activity

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 951 ◽  
Author(s):  
Michał Abendrot ◽  
Lilianna Chęcińska ◽  
Joachim Kusz ◽  
Katarzyna Lisowska ◽  
Katarzyna Zawadzka ◽  
...  
Keyword(s):  
Amino Acids ◽  
Antibacterial Activity ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
X Ray Diffraction ◽  
Organic Zinc ◽  
Counter Ions ◽  
Open Issue ◽  
Potential Use ◽  
Active Substances

The multifunctional profile of Zn2+ has influenced its great popularity in various pharmaceutical, food, and cosmetic products. Despite the use of different inorganic and organic zinc derivatives, the search for new zinc-containing compounds with a safer skin profile still remains an open issue. The present paper describes the synthesis, structural characterization, and antibacterial activity of zinc(II) complexes with proteinogenic amino acids as potential candidates for dermatological treatments. The obtained complexes are of the general formula [Zn(AA)2], where AA represents an amino acid (L-Glu, Gly, L-His, L-Pro, L-Met, and L-Trp). Their synthesis was designed in such a way that the final bis(aminoacidate) zinc(II) complexes did not contain any counter-ions such as Cl−, NO3−, or SO42− that can cause some skin irritations. The chemical structure and composition of the compounds were identified by 1H NMR spectroscopy and elemental analysis, and four were also characterized by single-crystal X-ray diffraction. The Hirshfeld surface analysis for the Zn2+ metallic center helped to determine its coordination number and geometry for each complex. Finally, the antibacterial properties of the complexes were determined with respect to three Gram-positive strains, viz. Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 12228, and Streptococcus pyogenes ATCC 19615, and two Gram-negative bacteria, viz. Escherichia coli ATCC 25992 and Pseudomonas aeruginosa ATCC 27853, and were compared with the activity of zinc 2-pirrolidone 5-carboxylate (ZnPCA), commonly applied in dermatology. It was found that the Zn(II) complexes with methionine and glycine exhibited a higher antibacterial activity than the tested standard, and the antimicrobial properties of complex with Trp were satisfactory. The results of the antimicrobial activity examination allow us to postulate that the obtained zinc complexes might become new active substances for use in dermatological products.

scholarly journals Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?

2017 ◽  
Vol 43 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Zahi Badran ◽  
Xavier Struillou ◽  
Francis J Hughes ◽  
Assem Soueidan ◽  
Alain Hoornaert ◽  
...  
Keyword(s):  
Silicon Nitride ◽  
Dental Implants ◽  
Dental Implant ◽  
Clinical Success ◽  
Treatment Options ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Future Research ◽  
Success Rates ◽  
Biological Performance

For decades titanium has been the preferred material for dental implant fabrication, with mechanical and biological performance resulting in high clinical success rates. These have been further enhanced by incremental development of surface modifications aimed at improving speed and degree of osseointegration and resulting in enhanced clinical treatment options and outcomes. However, increasing demand for metal-free dental restorations has also led to the development of ceramic-based dental implants, such as zirconia. In orthopedics, alternative biomaterials, such as polyetheretherketone or silicon nitride, have been used for implant applications. The latter is potentially of particular interest for oral use as it has been shown to have antibacterial properties. In this article we aim to shed light on this particular biomaterial as a future promising candidate for dental implantology applications, addressing basic specifications required for any dental implant material. In view of available preclinical data, silicon nitride seems to have the essential characteristics to be a candidate for dental implants material. This novel ceramic has a surface with potentially antimicrobial properties, and if this is confirmed in future research, it could be of great interest for oral use.

scholarly journals Supramolecular pyridyl urea gels as soft matter with antibacterial properties against MRSA and/or E. coli

2014 ◽  
Vol 50 (74) ◽  
pp. 10819-10822 ◽  
Author(s):  
Komala Pandurangan ◽  
Jonathan A. Kitchen ◽  
Salvador Blasco ◽  
Francesca Paradisi ◽  
Thorfinnur Gunnlaugsson
Keyword(s):  
Hydrogen Bonding ◽  
Soft Matter ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
E Coli ◽  
Supramolecular Gels

The development of a family of twelve aryl pyridyl ureas, their crystallography and the ability of a number of these to form hydrogen bonding supramolecular gels with antimicrobial properties are described.

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