scholarly journals The Effect of Laser Irradiation on Reparative Osteogenesis

2018 ◽  
Vol 1 (2) ◽  
pp. 10-19
Author(s):  
Yu. М. Iryanov ◽  
N. A. Kiryanov

Introduction: The use of non-medicinal facilities for correcting processes in various pathological conditions is one of the most urgent problems of modern medicine. Purpose of the Work: To study the effect of low-intensity infrared laser radiation on reparative bone formation and angiogenesis in bone regeneration which is formed in treatment of fractures under conditions of transosseous osteosynthesis. Material and Methods: A tibia fracture was modeled experimentally in rats in the control and experimental groups. Reposition and fixation of fragments were performed. The fracture zone in the experimental group animals was exposed to the impact of pulsed infrared laser irradiation of low intensity. Animals from the control group underwent the impact simulation. The operated bones were investigated using the methods of X-ray, light and electron microscopy, X-ray electron probe microanalysis. Results: It was established that laser radiation exposure sessions activated fibrillogenesis and angiogenesis, accelerated compacting of newly formed bone tissue and increased its maturity while primary fracture healing occurred. Prolonged capillary dilatation and endothelium-dependent vasodilation, intensive capillarogenesis were noted after sessions of laser therapy in bone regeneration. Endothelial outgrowth was formed in the lumen of the vessels forming capillary buds that propagate along the “mother” vessels (endovascular capillarogenesis). Conclusion: The data obtained revealed a possible mechanism of laser radiation exposure at the level of a whole organism and proved the effectiveness of its application in clinical practice at the early stages of patient rehabilitation under conditions of transosseous osteosynthesis.

2021 ◽  
Vol 12 (1) ◽  
pp. e13-e13
Author(s):  
Hannaneh Ghadirian ◽  
Allahyar Geramy ◽  
Mohammad Ali Keshvad ◽  
Soolmaz Heidari ◽  
Nasim Chiniforush

Introduction: Ceramic brackets have gained increasing popularity among dental clinicians and orthodontic patients but friction is a major concern when using them. This study sought to assess the effects of diode and Nd:YAG (neodymium-doped yttrium aluminum garnet) laser irradiation on friction forces between two types of ceramic brackets and rhodium-coated esthetic archwires. Methods: Thirty polycrystalline and 30 poly-sapphire brackets were divided into 6 groups (n=10) as follows: (I) control polycrystalline brackets (no laser irradiation), (II) polycrystalline brackets subjected to diode laser irradiation, (III) polycrystalline brackets subjected to Nd:YAG laser irradiation, (IV) control poly-sapphire brackets (no laser irradiation), (V) poly-sapphire brackets subjected to diode laser irradiation, and (VI) poly-sapphire brackets subjected to Nd:YAG laser irradiation. The bracket slots were laser-irradiated on a custom-made table. Sixty 5-cm pieces of rhodium-coated archwires were used for the friction test in a universal testing machine at a speed of 10 mm/min. Ten brackets from the six groups underwent scanning electron microscopy (SEM), X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX). Results: The frictional resistance value of polycrystalline brackets was significantly higher than that of poly-sapphire brackets, irrespective of laser type (P<0.05). Irradiation of diode and Nd:YAG lasers, compared with the control group, had no significant effect on friction, irrespective of bracket type (P>0.05). Conclusion: It appears that diode and Nd:YAG laser irradiation cannot significantly decrease the friction. Future studies are warranted on different laser types with variable exposure.


2019 ◽  
Vol 187 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Laurent Faroux ◽  
Thierry Blanpain ◽  
Anthony Fernandez ◽  
Pierre Nazeyrollas ◽  
Sophie Tassan-Mangina ◽  
...  

ABSTRACT Interventional cardiologists count among the health professionals that are most exposed to ionising radiation. To minimise exposure, it is recommended that the patient be placed at the maximum distance possible from the X-ray source, but this recommendation has not been clinically validated. We aimed to investigate the impact of the average table height on the level of radiation delivered to cardiologists performing coronary interventions. The population for analysis included all invasive coronary procedures performed in our centre from March to June 2017. The primary endpoint was operator radiation exposure, as assessed using personal electronic dosimeters located on the operator’s left arm. In total, 225 invasive coronary procedures were analysed. When the average table height was 1126 mm or more, the operators received a radiation dose that was, on average, 53% lower than when the table was lower than 1126 mm. This reduction remained significant by multivariate analysis adjusted for the operator.


Author(s):  
Maghfirotul Iffah ◽  
I Putu Gede Adiatmika ◽  
I Wayan Bandem Adnyana ◽  
I Dewa Putu Sutjana ◽  
I Made Muliarta ◽  
...  

Screening is ordinary process airport passanger was machine baggage. X-ray radiation gives impact to eye because eye sensitive of radiation. Many kinds of eye strain symptom got by screening worker such eye poignant. It is neressary to give  intervention to decrease the radiation exposure and eye strain for worker by increasing lead shielding on the fluoroscopy machine baggage and setting of worker distance toward the source of radiation.             Experimental research with pre-post test control group design. A sampel of 30 people were taken with a simple randomized method which was subdivided into group 1 as a control group without the additional treatment of lead shielding and working distance regulation of the radiation source, group 2 with the addition of a shielding and setting distance as far as 2 m. the study was conducted in August 2017. The variables evaluated were exposure to the received radiation of workes and the strain of the workers eyes.             The result of the research is a combination of  lead shielding on machine baggage fluoroscopy and setting of working distance to X ray source at X International Ariport significantly (p<0,05) in decreasing radiation exposure received by worker equal to 74,59% and worker eye strain 68,85% for a distance of 1,5 m and decreased radiation exposure to the workers as much as 93, 69% and the eye strain on the worker 89,79% at a distance of 2 m from the radiation source.             Concluded that the combination of increasing lead shielding and the setting of worker distance toward the source of radiation decrease thr radiation exposure and eye strain on the screening worker at X International airport.


Author(s):  
L. V. Brun ◽  
V. I. Makolinets

The aim of this study is to determine the influence of low-intensity infrared laser radiation (LIIRLR) on concentrationof diclofenac sodium in the experiment on rats by the method of high-performance liquid chromatography. For study conduct, a total of 15 male rats with body weight of 250–300 g were used. Experimental animals were subdivided into 3 groups. Animals of group 1 received diclofenac sodium per os at the dose of ED50 (8 mg/kg of animal body weight). Animals of group 2 received diclofenac sodium per os (8 mg/kg) and in 15 min were exposed to LIIRLR. Animals of group 3 were exposed to LIIRLR and in 15 min received diclofenac sodium per os at the dose of 8 mg/kg. Animals were sacrificed in 60 min after drug administration. For extraction of diclofenac sodium from rat plasma samples, we used a method of solid-phase extraction, which had been modified due to microoncentrationsof the active substance. In the result of the studies conducted, it has been determined that therapy regimen with the following sequence is the most efficient in the animals studied: exposure of LIIRLR and administration per os of diclofenac sodium in15 min. The results obtained indicate to the fact that concomitant use of LIIRLR potentiates diclofenac sodium. Itwill allow to decrease the dose, influence on its entry and duration of its action in the organism, as well as to decreasethe frequency of drug administration.


Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 295 ◽  
Author(s):  
Monika Herten ◽  
Christoph Zilkens ◽  
Fritz Thorey ◽  
Tjark Tassemeier ◽  
Sabine Lensing-Höhn ◽  
...  

The aim of this study was to elucidate the impact of autologous umbilical cord blood cells (USSC) on bone regeneration and biomechanical stability in an ovine tibial bone defect. Ovine USSC were harvested and characterized. After 12 months, full-size 2.0 cm mid-diaphyseal bone defects were created and stabilized by an external fixateur containing a rigidity measuring device. Defects were filled with (i) autologous USSC on hydroxyapatite (HA) scaffold (test group), (ii) HA scaffold without cells (HA group), or (iii) left empty (control group). Biomechanical measures, standardized X-rays, and systemic response controls were performed regularly. After six months, bone regeneration was evaluated histomorphometrically and labeled USSC were tracked. In all groups, the torsion distance decreased over time, and radiographies showed comparable bone regeneration. The area of newly formed bone was 82.5 ± 5.5% in the control compared to 59.2 ± 13.0% in the test and 48.6 ± 2.9% in the HA group. Labeled cells could be detected in lymph nodes, liver and pancreas without any signs of tumor formation. Although biomechanical stability was reached earliest in the test group with autologous USSC on HA scaffold, the density of newly formed bone was superior in the control group without any bovine HA.


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