scholarly journals ETHNIC FEATURES OF LIPID PROFILE AND LIPID PEROXIDATION IN FREESTYLE WRESTLERS

2019 ◽  
Vol 19 (2) ◽  
pp. 37-44
Author(s):  
N Kurashova ◽  
A Yureva ◽  
M Dolgikh ◽  
I Gutnik ◽  
L Kolesnikovа
Keyword(s):  
Lipid Peroxidation ◽  
Lipid Profile ◽  
Ethnic Group ◽  
Ethnic Groups ◽  
Reduced Glutathione ◽  
The Body ◽  
Antioxidant Protection ◽  
Physiological Basis ◽  
Lipid Exchange ◽  
Metabolic Intensity

Aim. The article deals with the assessment of the lipid profile, lipid peroxidation, and antioxidant protection in freestyle wrestlers belonging to different ethnic groups. Materials and methods. The study involved freestyle male wrestlers aged 18–22 with the rank of the Candidate for Master of Sport and Master of Sport regularly practicing freestyle wrestling. We studied a serum consisting of blood plasma and erythrocyte hemolysate. Lipid exchange was studied with the help of the BTS-350 analyzer (Spain) and BioSystems (Spain) reagents. To establish aminotransferase in blood serum, we used Vital (Russia) reagents. The components of lipid peroxidation and antioxidant protection were established with the help of spectrophotometric and fluorometric methods. Results. Freestyle athletes of the Russian ethnic group are characterized by a significantly lower TG concentrations compared to Buryat athletes. In the system of lipid peroxidation and antioxidant protection, in athletes of the Russian ethnic group, we revealed a significant AOA, reduced glutathione and retinol compared to Buryat athletes. Conclusion. The data obtained prove a different degree of metabolic activity in athletes from various ethnic groups. The balance between lipid oxidation and antioxidant protection mostly determines metabolic intensity as well as adaptation capacities of the body. The study of metabolic changes in highly-skilled athletes from different ethnic groups can contribute to the deepening of knowledge about the physiological basis and pathogenetic effects of stress on the human body. This will be one of the factors for optimizing training and providing the search for the ways of increasing physical activity as a mean of preserving the nation and sports development.

scholarly journals Influence of feed additive “Butaselmevit-Plus” on antioxidant status of rats in conditions of oxidative stress

2019 ◽  
Vol 21 (90) ◽  
pp. 76-81 ◽  
Author(s):  
T. V. Martyshuk ◽  
B. V. Gutyj
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Antioxidant Status ◽  
Reduced Glutathione ◽  
Antioxidant Properties ◽  
The Body ◽  
Feed Additive ◽  
Antioxidant Protection ◽  
Feed Supplement ◽  
Experimental Group

The purpose of the work was to investigate the effect of the feed supplement “Butaselmevit Plus” on the antioxidant status of the organism in rats under conditions of oxidative stress. The research was carried out on white, sexually-mature, young male rats of the Wistar line, with a body weight of 180–200 g, which was kept on a standard diet of the Institute vivarium of the State Scientific-Research Control Institute of Veterinary Preparations and Feed Supplements. The animals were divided into three groups of 20 animals in each: 1st group (K) intact animals; Group 2 (R1) – rats, affected with tetrachloromethane; Group 3 (R2) – rats, affected with tetrachloromethane and used as a feed additive “Butaselmevit-Plus”. The feed supplement “Butaselmevit-Plus” includes the fruits of thistle spotted, methionine, sodium selenite and vitamins A, E, D3. Significant violation of oxidative-antioxidant balance in animals under oxidative stress conditions, which is characterized, primarily, by activation of processes of radical lipid oxidation with excessive accumulation of both intermediate and final products of lipid peroxidation oxidation and inhibition of antioxidant defense system activity, is established. The development of oxidative stress leads to the inhibition of the activity of the glutathione system of antioxidant protection of the body of rats. This is evidenced by the low activity of glutathione peroxidase and the low level of reduced glutathione in the blood of experimental rats. The feed supplement “Butaselmeib-Plus” contributed to the activation of the system of antioxidant protection of the body of rats for tetrachloromethane poisoning, as evidenced by the increased activity of glutathione peroxidase and the level of reduced glutathione. In addition, in the blood of experimental rats, inhibition of lipid peroxidation and formation of free radicals was observed. It was determined that the level of lipids hydroperoxides on the 20th day of the experiment in blood of rats of experimental group R2 decreased by 35.7%, and the level of TBK-active products – by 21.6% relative to the indices of the first experimental group of rats. Thus, the feed supplement “Butaselmevit-Plus” when fed to rats for the development of oxidative stress inhibited lipid peroxidation, as indicated by the low level of lipids hydroperoxides and TBK-active products in their blood. This may be due to the fact that the feed additive includes two strong antioxidants, such as vitamin E and selenium, which in turn enhance the action of each other. It should also be noted that the antioxidant properties of thistle blisters, which, according to the literature, also possess antioxidant properties. It consists of vitamins B, A, E, K, precursors of vitamin D, carotenoids, macroelements – potassium, calcium, magnesium, ferrum and microelements – Cuprum, Zinc, Manganese, Iodine. The combined action of these biologically important elements exhibits high hepatoprotective and antioxidant activity.

scholarly journals Pro- and Antioxidant Activity in the Blood of Adolescents of Different Ethnic Groups

2019 ◽  
Vol 3 (6) ◽  
pp. 23-28
Author(s):  
N. A. Kurashova ◽  
E. A. Kudeyarova
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Reduced Glutathione ◽  
Antioxidant Defense System ◽  
The Body ◽  
Endocrine Disorders ◽  
Antioxidant Protection ◽  
Secondary Products ◽  
Adaptive Capabilities ◽  
Conjugated Trienes

Background. Processes of antioxidant protection in different ethnicities, living in the same geographical conditions, are of undoubted scientific interest. The ratio of activity of oxidative processes and antioxidant components not only reflects, but also largely determines the metabolism and adaptive capabilities of the organism. The key issue in understanding the regulatory and adaptive role of lipid peroxidation reactions in the body is the idea of the existence of a certain balance with the antioxidant defense system.Aims: to study the features of the system of lipid peroxidation and antioxidant protection in adolescents of different ethnicities, living in Eastern Siberia.Materials and methods. Parameters of lipid peroxidation and antioxidant protection were determined in the blood serum by spectrophotometric methods.Results. We found that adolescent Buryat boys had statistically significant decrease in primary and secondary products of lipid peroxidation: ketodienes and conjugated trienes, malondialdehyde, and components of antioxidant protection: retinol, α-tocopherol, the level of total antioxidant activity of blood and reduced glutathione, in comparison with Caucasian adolescents. In Caucasian adolescents with endocrine disorders, there was a statistically significant increase in the level of ketodienes and conjugated trienes, as well as the activity of superoxide dismutase against the background of a decrease of reduced glutathione, tocopherol, and retinol. We revealed a significant increase in the concentration of ketodienes and conjugated trienes and a decrease of the oxidized glutathione in adolescents with endocrine disorders in comparison with healthy adolescents of Buryat ethnicity.Conclusions. Studying of the processes of lipid peroxidation and antioxidant system of the organism can be used as an additional criterion for complex examination of practically healthy adolescents, which significantly enhance the representation about the adaptation possibilities of the organism to external conditions and can become a basis for effective examination of reproductive health in the future.

scholarly journals INFLUENCE OF «METISEVIT» ON THE ACTIVITY OF ENZYME AND NONENZYME LINK OF ANTIOXIDANT PROTECTION UNDER THE BULL’S BODY CADMIUM LOADING

2016 ◽  
Vol 18 (2(66)) ◽  
pp. 52-59
Author(s):  
B.V. Gutyj ◽  
Y. Lavryshyn ◽  
V. Binkevych ◽  
O. Binkevych ◽  
О. Paladischuk ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Vitamin E ◽  
Glutathione Peroxidase ◽  
Antioxidant Defense ◽  
Cadmium Stress ◽  
Antioxidant Defense System ◽  
The Body ◽  
Antioxidant Protection ◽  
Young Cattle

The article contains the research results of the effect of cadmium chloride on the indexes of enzyme and nonenzyme systems of  antioxidant defense system in young cattle, such as the activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels of vitamins A and E. It is established that feeding calves at a dose of toxicant 0.04 mg / kg activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels of vitamins A and E in the blood of experimental animals decreased throughout the experiment. The lowest indicators of antioxidant in the blood of young cattle is set on the twenty -fourth day of the experiment, which is associated with increased activation of lipid peroxidation and the balance between antioxidant system and lipid peroxidation intensity. Given the cadmium load of young cattle it is used a new integrated drug with antioxidant action «Metisevit», which includes metifen, sodium selenite and vitamin E wich is founded as stimulating effects on the activity of antioxidant protection. In particular,it is established probable increase in activity of catalase, superoxide dismutase, glutathione peroxidase, glutathione levels, vitamin A and vitamin E in the blood of young cattle, which has performed cadmium stress. These changes occur through comprehensive action components of the drug «Metisevit» that leads to the normalization of metabolic processes and free radical in the body of the bull. The results of the research indicate antioxidant drug «Metisevit» in the application of its young cattle and the validity of his administration to improve the body's antioxidant status of chronic cadmium toxicosis.

Effect of Bitters on the Body Weight, Lipid Profile, Catalase and Lipid Peroxidation in Experimental Animals

2012 ◽  
Vol 13 (1) ◽  
pp. 62-66 ◽  
Author(s):  
M.A. Alabi ◽  
R.M. Sunday ◽  
T. Olowokere ◽  
F.A. Kareem ◽  
F. Osanaiye
Keyword(s):  
Lipid Peroxidation ◽  
Body Weight ◽  
Lipid Profile ◽  
The Body ◽  
Experimental Animals

scholarly journals Memaknai Upacara Kematian dalam Bingkai Lokalitas Budaya Indonesia: Studi Kasus Tiga Cerpen Pilihan Kompas

2020 ◽  
Vol 2 (1) ◽  
pp. 14-22
Author(s):  
Awla akbar Ilma ◽  
Puri Bakthawar
Keyword(s):  
Short Stories ◽  
Ethnic Group ◽  
Ethnic Groups ◽  
Social Environment ◽  
Short Story ◽  
Natural World ◽  
The Body ◽  
Death Event ◽  
The Social ◽  
Plural Society

Indonesian is a multicultural plural society. Therefore, almost every ethnic group in Indonesia has varied tradition and culture, especially in responding to the phenomenon of obsequies through unique ceremonies and symbols. The research aims to examine how people in several ethnic groups responded to the death event through traditional ceremonies represented by literary works, especially short stories in the 2014-2017 Kompas Selections. Samples to be used in this study are the short story "In the Body of the Tarra, in the Womb of the Tree" by Faisal Oddang in 2014, the short story "Linuwih Aroma Jarik Baru" by Anggun Prameswari in 2015, and the short story "Kasur Tanah" by Muna Masyari in 2017. Results research shows that the three short stories elevate and interpret the tradition of obsequies in Javanese, Madura, and Toraja cultures. In Javanese society, kawung batik is a symbol of man's separation from the natural world. In Madurese society, Sortana is a "gift" of human separation from the social environment. In Toraja society, the tradition of passiliran becomes a symbol of the reuniting of humans with nature as the original.

scholarly journals Features of antioxidant system in patients with obstructive jaundice of benign and malignant origin in dynamics

2018 ◽  
Vol 99 (6) ◽  
pp. 919-923
Author(s):  
N G Elmanova
Keyword(s):  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Antioxidant Enzymes ◽  
Antioxidant System ◽  
Surgical Intervention ◽  
Reduced Glutathione ◽  
Malonic Dialdehyde ◽  
Antioxidant Protection ◽  
High Level

Aim. Study of the features of changes of antioxidant protection in patients with mechanical jaundice of benign and malignant origin in dynamics. Methods. The author studied the role of antioxidant system in the progression of mechanical jaundice of various origins in 104 patients. Groups of patients with a syndrome of mechanical jaundice of benign (62 patients) and malignant origin (42 patients) were isolated. The material of the study was blood from the ulnar vein, which was taken in the morning on an empty stomach before surgery. In the dynamics (on the 7th day after the operation), 53 patients were examined. To assess the state of antioxidant protection, a spectrophotometric method of investigation was used. Results. A high level of malonic dialdehyde, the product of lipid peroxidation, was determined in all patients regardless of origin. There was also a depression of the enzymatic link of antioxidant protection (a decrease in the activity of superoxide dismutase and catalase). After surgical intervention in patients with mechanical jaundice of benign origin, correction of the level of reduced glutathione was observed. In patients with mechanical jaundice of malignant origin in dynamics, the activity of antioxidant enzymes did not differ significantly from the norm (p1-3 = 0,23; p1-3 = 311). Conclusion. After surgical intervention, partial improvement of the condition of patients with mechanical jaundice of benign origin was observed, and dysfunction of antioxidant protection persisted in patients with mechanical jaundice of malignant origin.

scholarly journals Typical relationships between the indexes of lipid peroxidation/ antioxidant protection and immune regulation in the patients with chronic atrophic gastritis and stomach cancer

2020 ◽  
Vol 22 (5) ◽  
pp. 897-906
Author(s):  
O. V. Smirnova ◽  
V. V. Tsukanov ◽  
A. A. Sinyakov ◽  
O. L. Moskalenko ◽  
N. G. Elmanova ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lipid Peroxidation ◽  
Atrophic Gastritis ◽  
Normal Distribution ◽  
Antioxidant Defense ◽  
Malonic Dialdehyde ◽  
Chronic Atrophic Gastritis ◽  
The Body ◽  
Control Group ◽  
Antioxidant Protection

Chronic atrophic gastritis and gastric cancer represent distinct steps of one pathogenic process. The risk of developing cancer of the stomach is directly proportional to the degree of atrophic changes simultaneously detected in antral segment and in the body of the stomach. The role of immune system in transformation of precancerous diseases into cancer is beyond doubt. During development of the malignant disease, the changes in lipid peroxidation systems – antioxidant defense become significant and contribute to the progression of the tumor and the development of metastases. A simultaneous study of lipid peroxidation and antioxidant defense indices along with phagocytic activity will allow us to evaluate relative contribution of these processes to development of chronic atrophic gastritis and gastric cancer. Purpose of the present study was to assess correlations between the lipid peroxidation indices, i.e. antioxidant protection, and chemiluminescent activity of neutrophilic granulocytes and monocytes in chronic atrophic gastritis and gastric cancer. Forty patients with chronic gastritis, 22 patients with chronic atrophic gastritis and 40 patients with gastric cancer were examined. The control group consisted of 50 practically healthy age-matched volunteers. Evaluation of spontaneous and induced production of reactive oxygen species by neutrophils and monocytes was carried out by chemiluminescent analysis. The parameters of lipid peroxidation/ antioxidant protection were determined by spectrophotometric methods. Statistical data processing was carried out using the Statistica v. 8.0 program (StatSoft Inc., USA). The normal distribution of indices was tested using the Kolmogorov–Smirnov method (adjusted by Lillefors). Quantitative indicators, given the normal distribution, were described using the median (Me) and interquartile scatter (Q0.25-Q0.75). To study statistical significance of differences between quantitative characteristics, the Mann–Whitney test was used. To study strength of relationships of these indicators, the Pearson rank correlation coefficient (r) was calculated. The critical significance level (p) when testing statistical hypotheses was taken equal to 0.05. Correlation analysis showed that the weight of positive correlations increases in patients with chronic atrophic gastritis, and it decreases in patients with gastric cancer, the strength of the correlation dependence and new relationships appear between chemiluminescent activity of neutrophils and monocytes in a spontaneous and induced state, and the amounts of malonic dialdehyde, enzyme activities of superoxide dismutase and catalase. In chronic atrophic gastritis and gastric cancer we have established the features of correlation patterns between lipid peroxidation/antioxidant protection indices, and activity of neutrophils and monocytes.

scholarly journals DYNAMICS OF ANTI-ANTIOXIDANT SYSTEM INDICATORS IN THE POSTOPERATIVE PERIOD IN PATIENTS WITH PERIODONTITIS ACCOMPANIED BY DIFFERENT REACTIVATY OF THE ORGANISM

2021 ◽  
Vol 74 (9) ◽  
pp. 2187-2191
Author(s):  
Yurii Yu. Yarov ◽  
Iryna I. Tkachenko
Keyword(s):  
Lipid Peroxidation ◽  
Malonic Dialdehyde ◽  
Initial Therapy ◽  
The Body ◽  
Antioxidant Protection ◽  
Two Phase ◽  
Diene Conjugates ◽  
Periodontal Tissues ◽  
Total Antioxidant ◽  
Protection Activity

The aim is to study the dynamics of lipid peroxidation and antioxidant protection in the blood of patients with generalized periodontitis accompanied by normo-, hyper- and hyporeactivity of the body after patch surgery. Materials and methods: 216 people aged 45 between 55 years with a diagnosis of generalized periodontitis of II, III degree of severity, chronic course were examined. Depending on the condition of reactivity of the organism, patients were divided into three groups: the first consisted of people with normoreaction; the second included patients with hyperreaction; the third group was made up by people with hyporeaction. Patients after initial therapy, underwent patch surgery. Blood sampling was performed after surgery on the 1st, 2nd, 4th, 6th and 9th day. The content of diene conjugates, malonic dialdehyde and peroxide hemolysis of erythrocytes, superoxide dismutase activity, catalase, and total antioxidant activity was determined by the biochemical method. Results: Normoreaction was characterized by two-phase moderate activation of lipid peroxidation with maxima on the 1st and 6th day against the normalization of the balance of oxidative systems by the end of observations. For hyperreaction pronounced activation of lipid peroxidation (significant increase in the content of diene conjugates and malonic dialdehyde with a maximum on the 1st day) accompanied by depletion of antioxidant protection activity was typical. Hyporeaction was characterized by slow activation of lipid peroxidation (increase in diene conjugates and malonic dialdehyde with a maximum on the 4th day) accompanied by insufficient activity of antioxidant protection. Conclusion: Correction of altered parameters in patients with generalized periodontitis accompanied by impaired (hyper- and hypo-) reactivity of the body with bringing them to values of normoreactivity is considered to be a condition for optimizing mucosal wound healing after surgery and further stabilization of the periodontal tissues.

scholarly journals Age features of lipid peroxidation and antioxidant protection processes in girls and women tofalar ethnic groups

2010 ◽  
Vol 9 (5) ◽  
pp. 55-59 ◽  
Author(s):  
L. I. Kolesnikova ◽  
M. A. Darenskaya ◽  
V. V. Dolgikh ◽  
V. A. Shenin ◽  
S. V. Dutova ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Ethnic Groups ◽  
Age Groups ◽  
Antioxidant Protection ◽  
Lipid Peroxidation Products ◽  
Peroxidation Processes ◽  
Age Features

Research objective: studying lipid peroxidation and antioxidant protection processes in girls and women of 3 age groups living in Tofalariya (ethnic tofalars). Spectrophotometric, fluorometric and statistic methods (Student’s parametrical criterion and Fisher's coefficient) were used. It was determined that decrease of lipid peroxidation and antioxidant protection processes activity takes place in puberty period. We marked increase concentration of lipid peroxidation products and retinol. The elder age period is characterized by the raised intensity of peroxidation processes.

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