scholarly journals Correlation between HbA1c level and monocyte percentage in obesity

2020 ◽  
Vol 8 (1) ◽  
pp. 75
Author(s):  
Edward Kurnia Setiawan Limijadi ◽  
Meita Hendrianingtyas
Keyword(s):  
Diabetes Mellitus ◽  
Hba1c Level ◽  
Monitoring And Evaluation ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Obesity And Diabetes ◽  
Neutrophil Percentage ◽  
Private Laboratory ◽  
Spearman Test ◽  
Hba1c Levels

Background : HbA1c is one of the parameters that can be useful for diagnosing diabetes mellitus that can occur in obesity. Monocyte as an inflammatory cell is widely studied in relation to diabetes mellitus and obesity. The purpose of this study is to analyze the correlation between HbA1c levels and monocyte percentage in obesity.Methods : A Cross-sectional study of 30 medical students at a private laboratory in Semarang on March – April 2017 was done. The monocyte percentage included incomplete blood count was examined with the Sysmex XS-800i hematology analyzer, while HbA1c level was examined with Hemocue HbA1c 501 System. Spearman test was done for analyzing data with p <0.05 was considered statistically significant. Result and discussion : Median of HbA1c level was 5.8 ± 0.23%. Medians of leukocyte count, lymphocyte percentage, neutrophil percentage, and monocyte percentage were 8,600 ± 339,77 /μl, lymphocyte percentage 33% ± 1.19%, neutrophil percentage 56% ± 1.35%, and monocyte percentage of 9.0% ± 0.26%, respectively. Spearman test showed that correlation value (r) was 0.131 (p = 0.489).Conclusion and suggestion : There was no correlation between HbA1c levels and monocyte percentage in obesity. The increased of monocyte percentage can be used as monitoring and evaluation parameters in obesity that can lead to diabetes mellitus. Further study can be done in an obese population with older age as well as other parameters related to obesity and diabetes mellitus.

HBA1C IS ASSOCIATED WITH FRAILTY IN A GROUP OF ABORIGINAL AUSTRALIANS

2018 ◽  
pp. 1-4
Author(s):  
Z. Hyde ◽  
K. Smith ◽  
L. Flicker ◽  
D. Atkinson ◽  
S. Fenner ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Hba1c Level ◽  
Binary Logistic Regression ◽  
Glycated Haemoglobin ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Aboriginal Australians ◽  
Obesity And Diabetes ◽  
Hba1c Levels

In this cross-sectional study of 141 Aboriginal Australians aged ≥45 years living in the remote Kimberley region of Western Australia, we explored whether glycated haemoglobin (HbA1c) levels were associated with frailty. Sixty-four participants (45.4%) had a HbA1c level ≥6.5% and 84 participants (59.6%) were frail. A significant trend was observed with regard to HbA1c levels and frailty, with those having HbA1c levels ≥6.5% having the greatest prevalence of frailty (70.3%). In binary logistic regression analyses, having a HbA1c level ≥6.5% was associated with being frail after adjustment for age, sex, and education. This association was attenuated after further adjustment for body mass index (BMI). Poorer glycaemic control is very common and a potential risk factor for frailty in remote-living Aboriginal Australians, and appears to be partly mediated by BMI, a known risk factor for diabetes mellitus. Obesity and diabetes mellitus are potentially important modifiable risk factors for frailty.

scholarly journals Effects of Sitagliptin on HbA1c levels in uncontrolled hyperglycemia in diabetics using conventional OAD’s.

2020 ◽  
Vol 27 (05) ◽  
pp. 963-967
Author(s):  
Amar Nazir ◽  
Fida Muhammad Sheikh ◽  
Sheraz Saleem
Keyword(s):  
Diabetes Mellitus ◽  
Hba1c Level ◽  
Glycosylated Hemoglobin ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional ◽  
Entire Study ◽  
Dipeptidyl Peptidase 4 ◽  
Diagnostic Center ◽  
Dipeptidyl Peptidase 4 Inhibitors ◽  
Hba1c Levels

Objectives: The study anticipates to appraise HbA1c levels after three months of sitagliptin addition (100mg/day) to patients already using conventional oral antidiabetics in patients of type II diabetes mellitus who have a meager retort to these existing anti diabetics. Study Design: Mainly cross sectional prospective multicenter, open labeled study. Setting: Department of Medicine University medical diagnostic center & District Head Quarter Hospital Sargodha. Period: January 2017 to June 2017. Material & Methods: 100 inadequately controlled diabetics using different types of oral anti diabetics were chosen and an especially designed performa was accomplished. In our study we gave preference to those patients who were on preexisting oral anti diabetics and now dipeptidyl peptidase 4 inhibitors were added for the first time. The patients were instructed (at the baseline visit) to report during the subsequent visit about glycemic control. Patients were not clued-up that glycosylated hemoglobin control was the main seek of the study, so there was no chance for Pygmalion effect. Results: Levels of glycosylated hemoglobin were significantly reduced after three months of treatment compared to baseline, with a mean alteration in HbA1c level from baseline of −0.77% (range, −0.68 to − -0.86%) in the entire study population at three months. The percentage of patients who achieved an HbA1c level of <6.9% significantly increased after three months of treatment, reaching 58.1%. Conclusion: HbA1c significantly lowered in patients with type 2 diabetes mellitus on conventional OADs after adding sitagliptin.

scholarly journals Bi-directional association between allergic rhinitis and diabetes mellitus from the national representative data of South Korea

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tae Kyung Lee ◽  
Ye Jin Jeon ◽  
Sun Jae Jung
Keyword(s):  
Diabetes Mellitus ◽  
Sensitivity Analysis ◽  
Allergic Rhinitis ◽  
Cross Sectional Study ◽  
Study Data ◽  
Sectional Study ◽  
Medication History ◽  
Cross Sectional ◽  
Health And Nutrition ◽  
Hba1c Levels

AbstractAllergic rhinitis (AR) and diabetes mellitus (DM) share a common cause in inflammation; however, potential relationships between them are not clear. Therefore, we aimed to explore the associations between AR and DM. In this cross-sectional study, data were extracted from the Korean National Health and Nutrition Examination Survey 2007–2018 and weighted based on sociodemographic characters. AR and DM were defined by diagnoses thereof. Since self-reporting was not perfect, in order to complement the validity, we additionally performed sensitivity analysis by defining DM according to HbA1c and medication history. After excluding invalid data, the number of final participants was 29,246 (mean age, 54.95 ± 14.27 years). We calculated the odds ratio (OR) of newly self-reported DM among AR patients without DM history by multivariable logistic regression adjusted for potential confounders. A reverse association was also assessed. Patients with AR showed lower ORs for DM than those without AR (OR, 95% CI: men, 0.28, 0.19–0.42; women, 0.33, 0.24–0.46). Similarly, DM patients showed lower ORs for AR than patients without DM (men, 0.41, 0.31–0.56; women, 0.34, 0.25–0.46). The same results were obtained in sensitivity analysis defining DM according to HbA1c levels or DM treatment and in stratification analysis for age, residency, comorbidity, BMI, and menopause. In conclusion, we discovered that AR and DM show mutual inverse associations, regardless of sex, in individuals aged 30 years and older.

scholarly journals Individualised targets for insulin initiation in type 2 diabetes mellitus—the influence of physician and practice: a cross-sectional study in eight European countries

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e032040 ◽  
Author(s):  
Anne Meike Boels ◽  
Elwin Koning ◽  
Rimke C Vos ◽  
Kamlesh Khunti ◽  
Guy EHM Rutten
Keyword(s):  
Hba1c Level ◽  
Cross Sectional Study ◽  
Insulin Initiation ◽  
Related Factors ◽  
Cross Sectional ◽  
Or Practice ◽  
Patient Vignette ◽  
The Uk ◽  
Hba1c Levels

ObjectivesTo determine at what glycated haemoglobin (HbA1c) level physicians from eight European countries would initiate insulin in type 2 diabetes, which physician or practice related factors influenced this level and whether physicians would differentiate between a younger uncomplicated patient and an older patient with comorbidities.DesignCross-sectional study with data from the Guideline Adherence to Enhance Care study.Setting and participants410 physicians from both primary and secondary care from Belgium, France, Germany, Italy, Ireland, Sweden, the Netherlands and the UK.Outcome measuresPhysicians were asked at which HbA1c level they would initiate insulin for a young, uncomplicated patient (vignette 1) and for an older, complicated patient (vignette 2). We evaluated differences in HbA1c levels between physicians from different countries using analysis of variance. To identify physician and practice related factors associated with HbA1c level at initiation of insulin, we performed multivariable linear regression. Multiple imputation was used to deal with missing data.ResultsIn Germany, Ireland, Sweden, the Netherlands and the UK, the HbA1c levels for initiating insulin in vignette 2 (range: 60.0 to 66.0 mmol/mol; 7.6% to 8.2%) were higher than for vignette 1 (range: 57.2 to 64.2 mmol/mol; 7.4% to 8.0%). In multivariable analysis, the HbA1c level at which insulin was initiated only differed between countries (vignette 1): Dutch physicians initiated insulin at a lower HbA1c level compared with Belgium, France and the UK. No physician or practice factors were independently associated with HbA1c level at insulin initiation.ConclusionsWhen deciding on individualised HbA1c targets for insulin initiation, physicians from five countries took patient’s age and comorbidity into account. The HbA1c level at which physicians would initiate insulin therapy differed between countries.

scholarly journals The Correlation between the levels of HbA1c with Ureum and Creatinine in Patient with Type 2 Diabetes Mellitus

2019 ◽  
Vol 7 (5) ◽  
Author(s):  
Tri Prasetyorini ◽  
Karningsih Sudiro ◽  
Bagya Mujianto ◽  
Rus Martini
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Chronic Kidney Failure ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Glucose Levels ◽  
Type 2 Dm ◽  
Hba1c Levels

Introduction and Aims : Untransmitted diseases is the leading cause of death globally. Diabetes mellitus is one of the four priorities of untransmitted diseases. This disease is a chronic disease characterized by blood glucose levels that exceed normal values. High blood sugar levels (hyperglycemia) will cause various complications, one of which is chronic complications that can attack various organs such as eyes, kidneys, nerves and blood vessels. This study aims to find out the correlation between the results of the examination of HbA1c, urea and creatinine levels which is an indicator of complications of Chronic Kidney Failure in Type 2 DM patients. Methods : This research is a survey research using cross-sectional study design. The respondents in this study are Type 2 DM patients who filled out the questionnaire and examined levels of HbA1c, ureum, and creatinine. Analysis of the data performed by using the SPEARMEN test SPSS for Windows 17. Result : The result of the SPEARMEN analysis is p = 0,016 (p < 0.05) which means there is a relationship between the levels of HbA1c with age of respondent. Meanwhile, p = 0,84 (p>0,05) which means there is no relationship between HbA1c levels of type 2 DM with urea levels of type 2 DM patients. While, there is no relationship between HbA1c levels of type 2 DM with creatinine levels of type 2 DM with p = 0.693 (p > 0,05). Conclusions : There is a correlation between HbA1c levels of type 2 diabetes mellitus with the age of the respondent, but there is no correlation between HbA1c levels of type 2 diabetes mellitus with ureum levels of type 2 diabetes mellitus and there is no correlation between HbA1c levels with Creatinine levels of  type 2 diabetes mellitus patients.

HbA1c levels with albuminuria in diabetes mellitus patients

2021 ◽  
Vol 129 (4) ◽  
Author(s):  
Prema Hidayati ◽  
Indah Lestari Daeng Kanang ◽  
Dzulrizka Razak ◽  
Resky Pratiwi Lambang Basri
Keyword(s):  
Diabetes Mellitus ◽  
Hba1c Level ◽  
Kidney Diseases ◽  
Average Length ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
History Of ◽  
Tract Infections ◽  
The Relationship ◽  
Hba1c Levels

Introduction: The number of people with diabetes mellitus (DM) worldwide with kidney complications has increased. Glycemic control by assessing HbA1c levels is one factor that influences the occurrence of kidney damage in DM patients. This study aims to determine the relationship between HbA1c levels and the incidence of albuminuria in DM patients. Methods: This study was a cross-sectional analytic observational study with consecutive sampling techniques in DM patients who did not have urinary tract infections and had no history of other kidney diseases, which were then measured for HbA1c levels and protein in the urine. Results: A total of 20 patients (62.5 %) were female, and 12 patients (37.5 %) were male. The average age of the patients was 59.81±4.89 years, and the average length of suffering from DM was 6.21±2.27 years. The average HbA1c level was 8.63±2.15, with an HbA1c level >7 found in 21 patients (65.7 %). In this study, there were 21 patients (65.7 %) with uncontrolled HbA1c levels. In this study, the prevalence of negative albuminuria was 56.2 %, while the prevalence of positive albuminuria was 43.8 %. There was a significant relationship between uncontrolled HbA1c levels and the incidence of albuminuria in DM patients (p=0.03). Conclusion: Uncontrolled HbA1c levels were associated with the incidence of albuminuria in DM patients.

scholarly journals A cross sectional study of cutaneous manifestations in 300 patients of diabetes mellitus

2019 ◽  
Vol 6 (1) ◽  
pp. 150 ◽  
Author(s):  
Sandeep Khuraiya ◽  
Nancy Lal ◽  
Naseerudin . ◽  
Vinod Jain ◽  
Dilip Kachhawa
Keyword(s):  
Diabetes Mellitus ◽  
Fungal Infections ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cutaneous Manifestations ◽  
Female Ratio ◽  
Cutaneous Infections ◽  
Hba1c Levels

Background: Diabetes Mellitus (DM) is a worldwide problem and one of the most common endocrine disorder. The skin is affected by both the acute metabolic derangements and the chronic degenerative complications of diabetes.Methods: The present study was a one-year cross sectional study from January 2014 to December 2014. All confirmed cases of DM with cutaneous manifestations irrespective of age, sex, duration of illness and associated diseases, willing to participate in the study were included in the study. Routine haematological and urine investigations, FBS, RBS and HbA1c levels were carried out in all patients.Results: A total of 300 patients of diabetes mellitus with cutaneous manifestations were studied. Majority belonged to the 4th decade (33%) and 3rd decade (27.7%) respectively. Males constituted 65% of the cases and male to female ratio was 1.85:1. Type 2 DM was most commonly observed (96%). Among the 300 diabetic patients, 73 patients (24.3%) had good control of DM with HbA1c levels in the range of 6.5-7% while 132 patients (44%) had a poor control of DM with HbA1c levels >8%. Hypertension was the most commonly associated systemic illness (37.6%). Cutaneous infections (63%) were the most commonly observed manifestation of which fungal infections (35.3%) were most frequently observed. Some of the other dermatoses observed were generalized pruritus (15.3%), acrochordons (11%), acanthosis nigricans (6%), diabetic dermopathy (5.33%), diabetic foot (3%), peripheral vascular disease (2.66%), vitiligo (2.66%), xanthelasma palpebrarum (2.33%), diabetic bullae (1%). Cutaneous infections, dermatoses associated with microangiopathy were more common in the uncontrolled diabetic patients which was statistically significant.Conclusions: Infections were the most common cutaneous manifestations in diabetics followed by dermatoses most commonly associated with diabetes. Proper skin care and long-term control of blood glucose levels may reduce the risk of some of the skin diseases.

Effect of heterozygous beta thalassemia on HbA1c levels in individuals without diabetes mellitus: A cross sectional study

2019 ◽  
Vol 494 ◽  
pp. 132-137 ◽  
Author(s):  
D. Tsilingiris ◽  
K. Makrilakis ◽  
E. Voskaridou ◽  
S. Pagkrati ◽  
M. Dalamaga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Beta Thalassemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Hba1c Levels
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