scholarly journals Glass-based coatings on biomedical implants: a state-of-the-art review

2017 ◽  
Vol 3 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Francesco Baino ◽  
Enrica Verné
Keyword(s):  
Mechanical Properties ◽  
Bending Strength ◽  
State Of The Art ◽  
Antibacterial Properties ◽  
Porous Scaffolds ◽  
Bioactive Glasses ◽  
Metallic Substrates ◽  
Ocular Implants ◽  
Living Tissues ◽  
Joint Prostheses

AbstractBioactive glasses, invented by Prof. Larry L. Hench in the late 1960s, have revolutionized the field of biomaterials as they were shown to tightly bond to both hard and soft living tissues and to stimulate cells towards a path of regeneration and self-repair. However, due to their relatively poor mechanical properties (brittleness, low bending strength and fracture toughness), they are generally unsuitable for load-bearing applications. On the other hand, bioactive glasses have been successfully applied as coatings on the surface of stronger/tougher substrates to combine adequate mechanical properties with high bioactivity and, in some cases, additional extrafunctionalities (e.g. antibacterial properties, drug release). After giving a short overview of the main issues concerning the fabrication of glass coatings, this review provides a state-of-the-art picture in the field and specifically discusses the development of bioactive and hierarchical coatings on 3D porous scaffolds, joint prostheses, metallic substrates (e.g. wires or nails) for orthopedic fixation, polymeric meshes and sutures for wound healing, ocular implants and percutaneous devices.

scholarly journals A Comprehensive Review of Bioactive Glass Coatings: State of the Art, Challenges and Future Perspectives

Coatings ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 757 ◽  
Author(s):  
Rachele Sergi ◽  
Devis Bellucci ◽  
Valeria Cannillo
Keyword(s):  
Mechanical Properties ◽  
Tissue Repair ◽  
Soft Tissues ◽  
Bending Strength ◽  
State Of The Art ◽  
Thermal Spraying ◽  
Metal Alloys ◽  
Special Focus ◽  
Bioactive Glasses ◽  
Metallic Implants

Bioactive glasses are promising biomaterials for bone and tissue repair and reconstruction, as they were shown to bond to both hard and soft tissues stimulating cells towards a path of regeneration and self-repair. Unfortunately, due to their relatively poor mechanical properties, such as brittleness, low bending strength and fracture toughness, their applications are limited to non-load-bearing implants. However, bioactive glasses can be successfully applied as coatings on the surface of metallic implants to combine the appropriate mechanical properties of metal alloys to bioactivity and biocompatibility of bioactive glasses. In this review, several available coating techniques to coat metal alloys using bioactive glasses are described, with a special focus on thermal spraying, which nowadays is the most used to deposit coatings on metallic implants.

scholarly journals Sintering Behavior of a Six-Oxide Silicate Bioactive Glass for Scaffold Manufacturing

2020 ◽  
Vol 10 (22) ◽  
pp. 8279
Author(s):  
Elisa Fiume ◽  
Gianpaolo Serino ◽  
Cristina Bignardi ◽  
Enrica Verné ◽  
Francesco Baino
Keyword(s):  
Mechanical Properties ◽  
Thermal Analysis ◽  
Tissue Repair ◽  
Sintering Temperature ◽  
Thermal Analyses ◽  
Three Dimensional ◽  
Sintering Behavior ◽  
Porous Scaffolds ◽  
Bioactive Glasses ◽  
Different Temperatures

The intrinsic brittleness of bioactive glasses (BGs) is one of the main barriers to the widespread use of three-dimensional porous BG-derived bone grafts (scaffolds) in clinical practice. Among all the available strategies for improving the mechanical properties of BG-based scaffolds, strut densification upon sintering treatments at high temperatures represents a relatively easy approach, but its implementation might lead to undesired and poorly predictable decrease in porosity, mass transport properties and bioactivity resulting from densification and devitrification phenomena occurring in the material upon heating. The aim of the present work was to investigate the sinter-crystallization of a highly bioactive SiO2-P2O5-CaO–MgO–Na2O–K2O glass (47.5B composition) in reference to its suitability for the fabrication of bonelike foams. The thermal behavior of 47.5B glass particles was investigated upon sintering at different temperatures in the range of 600–850 °C by means of combined thermal analyses (differential thermal analysis (DTA) and hot-stage microscopy (HSM)). Then, XRD measurements were carried out to identify crystalline phases developed upon sintering. Finally, porous scaffolds were produced by a foam replica method in order to evaluate the effect of the sintering temperature on the mechanical properties under compression loading conditions. Assessing a relationship between mechanical properties and sintering temperature, or in other words between scaffold performance and fabrication process, is a key step towards the rationale design of optimized scaffolds for tissue repair.

Investigations of the Mechanical Properties of an Alumina Toughened Zirconia Ceramic for an Application in Joint Prostheses

2005 ◽  
Vol 284-286 ◽  
pp. 1019-1022 ◽  
Author(s):  
Sabine Begand ◽  
Thomas Oberbach ◽  
Wilfried Glien
Keyword(s):  
Mechanical Properties ◽  
Ceramic Composite ◽  
Bending Strength ◽  
Composite Ceramic ◽  
Wear Behaviour ◽  
Zirconia Ceramic ◽  
Al2o3 Ceramic ◽  
Wear Rates ◽  
Al2o3 Composite ◽  
Joint Prostheses

The objectives of this study were to investigate the mechanical properties of a ZrO2- Al2O3 composite ceramic. The mechanical strenght, wear behaviour and phase composition of the ceramic composite were analysed. The tested material showed a significantly higher bending strength compared to Al2O3- and ZrO2-Ceramic. According to the results of ring-on-disc, the wear rates were comparable to the Al2O3-Ceramic.

Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges

2019 ◽  
Vol 104 ◽  
pp. 109895 ◽  
Author(s):  
Gurbinder Kaur ◽  
Vishal Kumar ◽  
Francesco Baino ◽  
John C. Mauro ◽  
Gary Pickrell ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
State Of The Art ◽  
Glass Ceramics ◽  
Bioactive Glasses ◽  
Future Challenges

Structure and properties of compact articles from high-alloyed iron powder with adding of boron nitride

2020 ◽  
pp. 39-48
Author(s):  
B. O. Bolshakov ◽  
◽  
R. F. Galiakbarov ◽  
A. M. Smyslov ◽  
◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Boron Nitride ◽  
Grain Boundary ◽  
Bending Strength ◽  
Physical And Mechanical Properties ◽  
Operating Conditions ◽  
Structure And Properties ◽  
Steam Turbines ◽  
Friction Forces ◽  
Wide Range

The results of the research of structure and properties of a composite compact from 13 Cr – 2 Мо and BN powders depending on the concentration of boron nitride are provided. It is shown that adding boron nitride in an amount of more than 2% by weight of the charge mixture leads to the formation of extended grain boundary porosity and finely dispersed BN layers in the structure, which provides a high level of wearing properties of the material. The effect of boron nitride concentration on physical and mechanical properties is determined. It was found that the introduction of a small amount of BN (up to 2 % by weight) into the compacts leads to an increase in plasticity, bending strength, and toughness by reducing the friction forces between the metal powder particles during pressing and a more complete grain boundary diffusion process during sintering. The formation of a regulated structure-phase composition of powder compacts of 13 Cr – 2 Mо – BN when the content of boron nitride changes in them allows us to provide the specified physical and mechanical properties in a wide range. The obtained results of studies of the physical and mechanical characteristics of the developed material allow us to reasonably choose the necessary composition of the powder compact for sealing structures of the flow part of steam turbines, depending on their operating conditions.

scholarly journals Development of Biopolymeric Hybrid Scaffold-Based on AAc/GO/nHAp/TiO2 Nanocomposite for Bone Tissue Engineering: In-Vitro Analysis

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1319
Author(s):  
Muhammad Umar Aslam Khan ◽  
Wafa Shamsan Al-Arjan ◽  
Mona Saad Binkadem ◽  
Hassan Mehboob ◽  
Adnan Haider ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Guar Gum ◽  
Porous Scaffolds ◽  
Vitro Assay ◽  
Vitro Analysis ◽  
Nanocomposite Scaffolds

Bone tissue engineering is an advanced field for treatment of fractured bones to restore/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone tissue because of biodegradable and biocompatible characteristics. We report synthesis of nanocomposite based on acrylic acid (AAc)/guar gum (GG), nano-hydroxyapatite (HAp NPs), titanium nanoparticles (TiO2 NPs), and optimum graphene oxide (GO) amount via free radical polymerization method. Porous scaffolds were fabricated through freeze-drying technique and coated with silver sulphadiazine. Different techniques were used to investigate functional group, crystal structural properties, morphology/elemental properties, porosity, and mechanical properties of fabricated scaffolds. Results show that increasing amount of TiO2 in combination with optimized GO has improved physicochemical and microstructural properties, mechanical properties (compressive strength (2.96 to 13.31 MPa) and Young’s modulus (39.56 to 300.81 MPa)), and porous properties (pore size (256.11 to 107.42 μm) and porosity (79.97 to 44.32%)). After 150 min, silver sulfadiazine release was found to be ~94.1%. In vitro assay of scaffolds also exhibited promising results against mouse pre-osteoblast (MC3T3-E1) cell lines. Hence, these fabricated scaffolds would be potential biomaterials for bone tissue engineering in biomedical engineering.

scholarly journals Eco-Friendly, High-Density Fiberboards Bonded with Urea-Formaldehyde and Ammonium Lignosulfonate

Polymers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 220
Author(s):  
Petar Antov ◽  
Viktor Savov ◽  
Ľuboš Krišťák ◽  
Roman Réh ◽  
George I. Mantanis
Keyword(s):  
Mechanical Properties ◽  
Bending Strength ◽  
Urea Formaldehyde ◽  
Physical And Mechanical Properties ◽  
High Density ◽  
Thickness Swelling ◽  
Formaldehyde Content ◽  
Uf Resin ◽  
Natural Wood ◽  
European Standards

The potential of producing eco-friendly, formaldehyde-free, high-density fiberboard (HDF) panels from hardwood fibers bonded with urea-formaldehyde (UF) resin and a novel ammonium lignosulfonate (ALS) is investigated in this paper. HDF panels were fabricated in the laboratory by applying a very low UF gluing factor (3%) and ALS content varying from 6% to 10% (based on the dry fibers). The physical and mechanical properties of the fiberboards, such as water absorption (WA), thickness swelling (TS), modulus of elasticity (MOE), bending strength (MOR), internal bond strength (IB), as well as formaldehyde content, were determined in accordance with the corresponding European standards. Overall, the HDF panels exhibited very satisfactory physical and mechanical properties, fully complying with the standard requirements of HDF for use in load-bearing applications in humid conditions. Markedly, the formaldehyde content of the laboratory fabricated panels was extremely low, ranging between 0.7–1.0 mg/100 g, which is, in fact, equivalent to the formaldehyde release of natural wood.

scholarly journals Electrospun PCL Patches with Controlled Fiber Morphology and Mechanical Performance for Skin Moisturization via Long-Term Release of Hemp Oil for Atopic Dermatitis

Membranes ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 26
Author(s):  
Sara Metwally ◽  
Daniel P. Ura ◽  
Zuzanna J. Krysiak ◽  
Łukasz Kaniuk ◽  
Piotr K. Szewczyk ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Atopic Dermatitis ◽  
Mechanical Performance ◽  
Antibacterial Properties ◽  
Skin Condition ◽  
Fiber Morphology ◽  
Suitable Material ◽  
Hemp Oil ◽  
Skin Moisture

Atopic dermatitis (AD) is a chronic, inflammatory skin condition, caused by wide genetic, environmental, or immunologic factors. AD is very common in children but can occur at any age. The lack of long-term treatments forces the development of new strategies for skin regeneration. Polycaprolactone (PCL) is a well-developed, tissue-compatible biomaterial showing also good mechanical properties. In our study, we designed the electrospun PCL patches with controlled architecture and topography for long-term release in time. Hemp oil shows anti-inflammatory and antibacterial properties, increasing also the skin moisture without clogging the pores. It can be used as an alternative cure for patients that do not respond to traditional treatments. In the study, we tested the mechanical properties of PCL fibers, and the hemp oil spreading together with the release in time measured on skin model and human skin. The PCL membranes are suitable material as patches or bandages, characterized by good mechanical properties and high permeability. Importantly, PCL patches showed release of hemp oil up to 55% within 6 h, increasing also the skin moisture up to 25%. Our results confirmed that electrospun PCL patches are great material as oil carriers indicating a high potential to be used as skin patches for AD skin treatment.

scholarly journals Effect of Sintering Temperature on Microstructure and Mechanical Properties of Hot-Pressed Fe/FeAl2O4 Composite

Crystals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 422
Author(s):  
Kuai Zhang ◽  
Yungang Li ◽  
Hongyan Yan ◽  
Chuang Wang ◽  
Hui Li ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bending Strength ◽  
Sintering Temperature ◽  
Raw Materials ◽  
Hot Press ◽  
Microstructure And Mechanical Properties ◽  
Powder Particles ◽  
Hot Press Sintering ◽  
Sintering Method

An Fe/FeAl2O4 composite was prepared with Fe-Fe2O3-Al2O3 powder by a hot press sintering method. The mass ratio was 6:1:2, sintering pressure was 30 MPa, and holding time was 120 min. The raw materials for the powder particles were respectively 1 µm (Fe), 0.5 µm (Fe2O3), and 1 µm (Al2O3) in diameter. The effect of sintering temperature on the microstructure and mechanical properties of Fe/FeAl2O4 composite was studied. The results showed that Fe/FeAl2O4 composite was formed by in situ reaction at 1300 °C–1500 °C. With the increased sintering temperature, the microstructure and mechanical properties of the Fe/FeAl2O4 composite showed a change law that initially became better and then became worse. The best microstructure and optimal mechanical properties were obtained at 1400 °C. At this temperature, the grain size of Fe and FeAl2O4 phases in Fe/FeAl2O4 composite was uniform, the relative density was 96.7%, and the Vickers hardness and bending strength were 1.88 GPa and 280.0 MPa, respectively. The wettability between Fe and FeAl2O4 was enhanced with increased sintering temperature. And then the densification process was accelerated. Finally, the microstructure and mechanical properties of the Fe/FeAl2O4 composite were improved.

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