Dual frequency bioelectrical impedance analysis to estimate hematocrit for prognosis of dengue fever in Indian children

2019 ◽  
Vol 64 (4) ◽  
pp. 459-469 ◽  
Author(s):  
Neelamegam Devarasu ◽  
Gnanou Florence Sudha

Abstract A noninvasive investigation to ascertain the hematocrit (HCT) or packed cell volume (PCV) was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical impedance analysis (BIA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as HCT level, platelet (PLT) count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were taken for the classification of risk as low risk (LR) and high risk (HR) DHF. Electrical conductivity of blood reflects a linear correlation with HCT. To provide a better and more accurate estimate of HCT, a dual frequency method is proposed to calculate the conductivities of plasma and blood cells. The resistance at 100 kHz is used to estimate the conductivity of blood cells and the impedance at 5 kHz to estimate the conductivity of plasma. Statistical analysis reveals that the HCT estimated using the proposed dual frequency method shows a significant difference with a single frequency (50 kHz) estimate of HCT and also shows a good correlation with the blood investigation results. In addition, statistical analysis of the proposed method on different fever subjects indicates a significant difference with DHF.

2020 ◽  
Vol 65 (4) ◽  
pp. 417-428
Author(s):  
Neelamegam Devarasu ◽  
Gnanou Florence Sudha

AbstractA noninvasive investigation to ascertain the platelet (PLT) count was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical phase angle (BPhA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as hematocrit (HCT) level, PLT count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were performed for the classification of risk as low-risk (LR) and high-risk (HR) DHF. It was found that the BPhA of the body reflects a linear correlation with the PLT count. To provide a better and more accurate estimate of PLT, a dual-frequency method is proposed to calculate the phase angle of the total body. The resistance at 5 kHz and reactance at 100 kHz were used to estimate the phase angle of the total body. The statistical analysis identified that the PLT count estimated using the proposed dual-frequency method shows a good correlation with the blood investigation results. In addition, statistical analysis of the proposed method on other fever subjects indicated a significant difference with DHF.


2012 ◽  
Vol 109 (4) ◽  
pp. 639-647 ◽  
Author(s):  
Saijuddin Shaikh ◽  
Kerry J. Schulze ◽  
Anura Kurpad ◽  
Hasmot Ali ◽  
Abu Ahmed Shamim ◽  
...  

Equations for predicting body composition from bioelectrical impedance analysis (BIA) parameters are age-, sex- and population-specific. Currently there are no equations applicable to women of reproductive age in rural South Asia. Hence, we developed equations for estimating total body water (TBW), fat-free mass (FFM) and fat mass in rural Bangladeshi women using BIA, with 2H2O dilution as the criterion method. Women of reproductive age, participating in a community-based placebo-controlled trial of vitamin A or β-carotene supplementation, were enrolled at 19·7 (sd 9·3) weeks postpartum in a study to measure body composition by 2H2O dilution and impedance at 50 kHz using multi-frequency BIA (n 147), and resistance at 50 kHz using single-frequency BIA (n 82). TBW (kg) by 2H2O dilution was used to derive prediction equations for body composition from BIA measures. The prediction equation was applied to resistance measures obtained at 13 weeks postpartum in a larger population of postpartum women (n 1020). TBW, FFM and fat were 22·6 (sd 2·7), 30·9 (sd 3·7) and 10·2 (sd 3·8) kg by 2H2O dilution. Height2/impedance or height2/resistance and weight provided the best estimate of TBW, with adjusted R2 0·78 and 0·76, and with paired absolute differences in TBW of 0·02 (sd 1·33) and 0·00 (sd 1·28) kg, respectively, between BIA and 2H2O. In the larger sample, values for TBW, FFM and fat were 23·8, 32·5 and 10·3 kg, respectively. BIA can be an important tool for assessing body composition in women of reproductive age in rural South Asia where poor maternal nutrition is common.


2017 ◽  
Vol 42 (2) ◽  
pp. 157-165 ◽  
Author(s):  
Megumi Ohta ◽  
Taishi Midorikawa ◽  
Yuki Hikihara ◽  
Yoshihisa Masuo ◽  
Shizuo Sakamoto ◽  
...  

This study examined the validity of segmental bioelectrical impedance (BI) analysis for predicting the fat-free masses (FFMs) of whole-body and body segments in children including overweight individuals. The FFM and impedance (Z) values of arms, trunk, legs, and whole body were determined using a dual-energy X-ray absorptiometry and segmental BI analyses, respectively, in 149 boys and girls aged 6 to 12 years, who were divided into model-development (n = 74), cross-validation (n = 35), and overweight (n = 40) groups. Simple regression analysis was applied to (length)2/Z (BI index) for each of the whole-body and 3 segments to develop the prediction equations of the measured FFM of the related body part. In the model-development group, the BI index of each of the 3 segments and whole body was significantly correlated to the measured FFM (R2 = 0.867–0.932, standard error of estimation = 0.18–1.44 kg (5.9%–8.7%)). There was no significant difference between the measured and predicted FFM values without systematic error. The application of each equation derived in the model-development group to the cross-validation and overweight groups did not produce significant differences between the measured and predicted FFM values and systematic errors, with an exception that the arm FFM in the overweight group was overestimated. Segmental bioelectrical impedance analysis is useful for predicting the FFM of each of whole-body and body segments in children including overweight individuals, although the application for estimating arm FFM in overweight individuals requires a certain modification.


2020 ◽  
Author(s):  
Jenn-Yeu Wang ◽  
Shu- Chin Chen ◽  
Betau Hwang

Abstract Background Maintenance hemodialysis patients often experience protein- calorie malnutrition. Our aim is to evaluate the independent prediction accuracy of bioelectrical impedance analysis derived variables by the measurements of upper arm anthropometry and clinical laboratory indexes for evaluation of nutritional status of hemodialysis patients. Furthermore, the relationship between measurements of upper arm anthropometry and clinical laboratory indexes and cross –sectional evaluation of the prevalence of malnutrition with the use of the norms and thresholds were done. Methods In a cross- sectional survey of 32 stable hemodialysis patients (aged 28 to 82 years) in hemodialysis unit of Taipei Municipal Zhongxiao Hospital, we evaluated measurements of upper arm anthropometry with measurements of single frequency bioelectrical impedance analysis and clinical laboratory indexes. Results The comparisons between measurements of upper arm anthropometry with measurements of single frequency bioelectrical impedance analysis and some of clinical laboratory indexes were statistically significant. This study further found that both mid-arm fat area and triceps skin-fold thickness were independent contributors to percent fat mass after adjustment for body mass index and gender in the multiple regression models. This study also demonstrated that mid-arm muscle circumference, or mid-arm muscle area, or corrected mid-arm muscle area independently predicted height normalized indices of fat-free mass respectively after adjustment for body mass index and gender in the multiple regression models. The prevalence of protein wasting measured by mid-arm muscle circumference (50%) appears to be equivalent to that measured by serum albumin concentration (50%). Conclusions Mid-arm muscle and fat variables by upper arm anthropometry correlated with nutritional variables of single frequency bioelectrical impedance analysis and clinical laboratory indexes. Mid-arm muscle and fat variables by upper arm anthropometry were independent predictors of body composition regarding height-normalized indices of fat-free mass and percent fat mass of hemodialysis patients even after adjustment of gender and BMI.


2019 ◽  
Vol 11 (1) ◽  
pp. 17
Author(s):  
Madeleine N. W. Senduk ◽  
Hedison Polii ◽  
Diana V. D. Doda

Abstract: Osteopenia commonly occurs in people over 50 years, however, several studies also showed that osteopenia affected young adults. Osteopenia can develop into osteoporosis. International Osteoporosis Foundation estimated that women in Indonesia had risk of developing osteoporosis four times greater than men. Osteopenia and osteoporosis can be prevented by physical exercise such as aerobic exercises inter alia Zumba exercise. This study was aimed to determine whether there was a difference in bone mass before and after 4-week Zumba exercise. This was an experimental study with one group pretest and posttest design conducted on 16 subjects of adult females in a fitness center in Manado, North Sulawesi. Zumba exercise was performed in 4 weeks. Bone mass before and after Zumba exercise was measured by using Bioelectrical Impedance Analysis (BIA). Data were analyzed with paired sample t-test. The results showed that the average of bone mass before Zumba exercise was 2.281 kg and the average of bone mass after Zumba exercise was 2.306 kg with a P value of 0.104. Conclusion: There was no significant difference in bone mass before and after 4-week Zumba exercise.Keywords: bone mass, Zumba exerciseAbstrak: Osteopenia umumnya terjadi pada orang berusia di atas 50 tahun, namun beberapa penelitian menunjukkan bahwa osteopenia telah menyerang usia muda. Osteopenia dapat berlanjut menjadi osteoporosis. Menurut International Osteoporosis Foundation, risiko osteoporosis pada wanita di Indonesia 4 kali lebih tinggi dibandingkan pria. Osteopenia dan osteoporosis dapat dicegah dengan melakukan aktivitas fisik seperti olahraga aerobik, antara lain senam Zumba. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan massa tulang sebelum dan sesudah melakukan senam Zumba. Jenis penelitian ialah eksperimental lapangan dengan rancangan one group pretest dan posttest yang dilakukan pada 16 wanita dewasa pada salah satu pusat kebugaran di Manado, Sulawesi Utara. Senam Zumba dilaksanakan selama 4 minggu. Massa tulang sebelum dan sesudah senam Zumba diukur menggunakan Bioelectrical Impedance Analysis (BIA). Uji statistik dilakukan menggunakan uji t berpasangan. Hasil penelitian menunjukkan rerata massa tulang sebelum senam Zumba 2,281 kg dan rerata massa tulang sesudah senam Zumba selama 4 minggu 2,306 kg dengan nilai P=0,104. Simpulan: Tidak terdapat perbedaan bermakna antara massa tulang sebelum dan sesudah melakukan senam Zumba selama 4 minggu.Kata kunci: massa tulang, senam Zumba


2021 ◽  
Vol 9 ◽  
Author(s):  
David J. Farbo ◽  
Deborah J. Rhea

Background: Body mass index (BMI) is frequently labeled as “flawed” in assessing obesity since it cannot differentiate between muscle and fat leading to misclassifications of healthy individuals. Bioelectrical impedance analysis (BIA) may be a more accurate indicator of obesity since it can distinguish the difference between muscle and fat in children. This pilot study investigated discrepancies between BMI and BIA body composition classifications in children with high levels of physical activity.Methods: Participants were selected from three elementary schools (N = 380, K = 76, 1st = 64, 2nd = 62, 3rd = 61, 4th = 83, and 5th = 34) receiving 60 min of outdoor, unstructured play daily. BIA scales were used to collect each child's body fat percentage and BMI score, then those numbers were categorized by BIA and BMI normative values as either underweight, healthy, overweight, or obese.Results: Overall, 26% of the students were classified differently when using the normative classifications for BMI and BIA, with the largest discrepancy found in the overweight category at 38%. Similar inconsistencies were found when students were divided as younger (42%) vs older students (36%), and males (40%) vs. females (35%).Conclusions: This pilot study demonstrated that there is a significant difference in how BMI and BIA discriminate between the different body composition categories. BIA consistently shows to be a more accurate tool in assessing obesity rates in children since it directly measures body fat.


1995 ◽  
Vol 29 (11) ◽  
pp. 1091-1095 ◽  
Author(s):  
Eugene L Coodley ◽  
Jack L Segal ◽  
David Hg Smith ◽  
Joel M Neutel

Objective: To compare changes in bioimpedance parameters and calculated total body water (TBW) with conventional measurements used to assess the efficacy of diuretic therapy in the treatment of heart failure. Setting: A Veterans Affairs tertiary care, teaching hospital. Subjects: Twelve patients with New York Heart Association (NYHA) class HI congestive heart failure (CHF). Design: Prospective, consecutive sample, cohort, open label. Interventions: Parenterally administered furosemide; clinically dictated, outcome-oriented, adjunctive therapy of CHF. Outcomes: Bioelectrical impedance analysis (BIA) parameters, measured volume of diuresis and changes in body weight, defined clinical endpoints (NYHA criteria). Results: Three days of diuretic therapy with furosemide (oral and/or intravenous) for CHF was associated with a measured weight loss of 4.1 ± 0.6 kg and statistically significant increases in resistance and reactance of 20.8% ± 2.7% and 22.7% ± 6.1%, respectively (p < 0.005). Calculated TBW using BIA parameters and standard equations decreased on average by 6.1 ± 0.6 L or 11.2% ± 1.1% (p < 0.001). A significant inverse correlation was observed between change in measured body weight and total body reactance (p = 0.02). Conclusions: Single-frequency BIA appears to have limited clinical usefulness as a method of assessing diuretic therapy in the management of CHF. Its greatest usefulness appears to lie in the assessment of serial changes in individual patients and patient populations that are physiologically or metabolically homogeneous. Further studies are needed to establish the validity of BIA in patients with decompensated CHF.


2000 ◽  
Vol 23 (3) ◽  
pp. 168-172 ◽  
Author(s):  
B. Oe ◽  
C.W.H. De Fijter ◽  
A.B.M. Geers ◽  
P.F. Vos ◽  
A.J.M. Donker ◽  
...  

Several equations are available to derive lean body mass (LBM) from bioelectrical impedance analysis (BIA). The purpose of this study was to investigate in dialysis patients the impact of the equation used on the outcome of LBM assessment. To avoid dyshydration as a confounder, vena cava diameter measurement was used to assess normohydration in the 21 patients studied. Five equations were compared. In a previously published study to assess total body water using antipyrine as a gold standard, Deurenberg's formula was advocated to be used in the estimation of LBM by BIA. Therefore, this formula was used as a basis for comparison with the other four equations. One equation gave results comparable to those obtained by Deurenberg's formula. Despite high correlations and agreement according to Bland and Altman analysis, the other three equations showed a significant difference with Deurenberg-derived LBM. Thus, the equation used has a major impact on the outcome of LBM estimations. (Int J Artif Organs 2000; 23: 168–72)


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