scholarly journals Sudden sex hormone withdrawal and the effects on body composition in late pubertal adolescents with gender dysphoria

2020 ◽  
Vol 33 (1) ◽  
pp. 107-112
Author(s):  
Rahul Ghelani ◽  
Cheryl Lim ◽  
Caroline Brain ◽  
Mary Fewtrell ◽  
Gary Butler
Keyword(s):  
Body Composition ◽  
Gender Dysphoria ◽  
Hormone Secretion ◽  
Sex Hormone ◽  
The Body ◽  
Composition Analysis ◽  
Reproductive Hormone ◽  
Test Analysis ◽  
Therapeutic Protocol ◽  
Composition Changes

AbstractBackgroundSex hormones initiate profound physical and physiological changes during the pubertal process, but to what extent are they responsible for continuing the body composition changes of late adolescence and what happens to body composition on sudden sex hormone withdrawal?MethodsThirty-six healthy, phenotypically and chromosomally normal late and post-pubertal individuals aged 15–17 years with gender dysphoria (transgirls – birth-registered males identifying as female n = 11; and transboys – birth-registered females identifying as male n = 25) underwent Tanita body composition analysis at 0, 6 and 12 months during reproductive hormone suppression with Triptorelin as part of the standard therapeutic protocol.Results and conclusionsIn the transgirl cohort, paired t-test analysis demonstrated a significant decrease in height and lean mass standard deviation scores over the 12-month period, going against an expected trajectory over that time. In contrast, oestrogen suppression appeared not to affect the body composition of transboys; their measurements were not significantly different at baseline and after 12 months of treatment. The withdrawal of sex hormone secretion does not appear to have a significant impact on female post-pubertal body composition, in contrast to that seen at the menopause. This suggests that other factors may preserve normal body balance in adolescents in the absence of sex steroids.

scholarly journals Ichthyometry and electrical bioimpedance analysis to estimate the body composition of tambatinga

2014 ◽  
Vol 44 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Francisco Teixeira Andrade ◽  
Márvio Lobão Teixeira de Abreu ◽  
João Batista Lopes ◽  
Agustinho Valente de Figueiredo ◽  
Maria de Nazaré Bona Alencar Araripe ◽  
...  
Keyword(s):  
Body Composition ◽  
Water Content ◽  
Correlation Coefficients ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Body ◽  
Composition Analysis ◽  
Average Weight ◽  
Electrical Bioimpedance ◽  
The Relationship

Body composition analysis is relevant to characterize the nutritional requirements and finishing phase of fish. The aim of this study was to investigate the relationship between ichthyometric (weight, total and standard length, density and yields), bromatological (fat, protein, ash and water content) and bioelectrical-impedance-analysis (BIA) (resistance, reactance, phase angle and composition indexes) variables in the hybrid tambatinga (Colossoma macropomum × Piaractus brachypomus). In a non-fertilized vivarium, 520 juveniles were housed and fed commercial rations. Then, 136 days after hatching (DAH), 15 fish with an average weight of 37.69 g and average total length of 12.96 cm were randomly chosen, anesthetized (eugenol) and subjected to the first of fourteen fortnightly assessments (BIA and biometry). After euthanasia, the following parts were weighed: whole carcass with the head, fillet, and skin (WC); fillet with skin (FS); and the remainder of the carcass with the head (CH). Together, FS and CH were ground and homogenized for the bromatological analyses. Estimates of the body composition and yields of tambatinga, with models including ichthyometric and BIA variables, showed correlation coefficients ranging from 0.81 (for the FS yield) to 1,00 (for the total ash). Similarly, models that included only BIA variables had correlation coefficients ranging from 0.81 (FS and CH yields) to 0.98 (for the total ash). Therefore, in tambatinga, the BIA technique allows the estimation of the yield of the fillet with skin and the body composition (water content, fat, ash, and protein). The best models combine ichthyometric and BIA variables.

scholarly journals Correlation Between Body Composition Analysis and Biochemical Nutritional Markers in Maintenance Hemodialysis Patients with Chronic Liver Disease

2020 ◽  
Vol 71 (11) ◽  
pp. 94-100
Author(s):  
Luciana Carmen Nitoi ◽  
Valeriu Ardeleanu ◽  
Anca Pantea Stoian ◽  
Lavinia Alexandra Moroianu
Keyword(s):  
Body Composition ◽  
Liver Disease ◽  
Nutritional Status ◽  
Chronic Liver Disease ◽  
The Body ◽  
Chronic Liver ◽  
Composition Analysis ◽  
Arterial Line ◽  
Body Protein ◽  
Total Body

Several approaches have been used to assess protein-energy wasting syndrome, such as clinical evaluation, biochemical nutritional markers, anthropometric measurements, but Bioelectrical Impedance Analysis (BIA) techniques hold a central place in clinical settings. The aim of this study is to report our clinical experience with BIA and the correlations between biochemical nutritional markers and BIA nutritional parameters in hemodialysis (HD) patients associating or free of chronic liver disease. This cross-sectional observational study included 69 HD patients divided into two groups: 33 with chronic liver disease (CLD+) versus 36 chronic liver disease-free (CLD-) from one HD unit in Romania. Serum albumin (SA), serum creatinine (SCr) and C-reactive protein (CRP) were obtained from the HD arterial line immediately before the HD session and by BIA the body composition including total body water (TBW), total body fat (TBF), lean fat free mass(LFFM), body muscular mass (BMM), malnutrition index and body protein reserve (PR) were assessed. No significant differences between groups were found in BCM, BMM, PR and TBF (p = 0.92, p = 0.60, p = 0.907, and p = 0.634, respectively). Malnutrition index had a significantly higher mean value in HD-CLD(+) patients (p = 0.00). HD-CLD(-) group showed a strong correlation between SA and SCr and BCM, BMM (kg), LFFM (kg) and body PR (kg) (r=.48, r=.50, r=.44, r=.50; resp. r=.42, r=.40, r=.36, r=.42). In HD-CLD(+) patients, a significant positive correlation was found between SA and SCr and LFFM and body PR (r=.37, r=.35; resp. r=.44, r=.35). Discussion: BIA is one of the most accurate techniques for assessing nutritional status and should be regularly used in clinical practice along with biochemical nutritional markers in HD patients. Although the protein metabolism depends to a large extent on liver function, CLD cannot be considered as having a significant impact on nutritional status in HD patients.

scholarly journals P432 Effects and safety of a colon-long absorbing budesonide product in patients with mild to moderate ulcerative colitis

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S393-S394
Author(s):  
D Pigniczki ◽  
K Szántó ◽  
M Rutka ◽  
K Farkas ◽  
A Bálint ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Body Composition ◽  
Side Effects ◽  
Disease Activity ◽  
The Body ◽  
Composition Analysis ◽  
Hormonal Changes ◽  
Aminosalicylic Acid ◽  
Laboratory Parameters ◽  
Body Composition Analysis

Abstract Background Budesonide is an oral corticosteroid, which is widely used in moderate-to-severe ulcerative colitis (UC) to obtain and maintain remission in those cases, where 5-aminosalicylic-acid was ineffective. Unlike previous forms of budesonide absorbing from the ileal and ascending colon region, the new-generation budesonide-MMX contains a formula, that allows absorption throughout the whole colon, and therefore in the whole potentially inflamed area in UC. We aimed to evaluate the effects and safety of budesonide-MMX in our UC patients who meet the above mentioned therapeutic demands in a real-life study. Methods We enrolled 22 patients with mild to severe UC in this single-centre prospective study until August of 2019. Patients received 9 mg oral budesonide-MMX once daily until 8 weeks. Laboratory parameters (cholesterol, triglyceride, CRP) and serum hormone levels (parathormone [PTH], dehydroepiandrosterone [DHEA] and cortisol) were monitored before and after the 8-week therapy to follow metabolic and hormonal changes. During these visits, body composition analysis was also performed with InBody 770 machine to observe the adverse steroid effects of budesonide-MMX in respect of body fat mass, body mass index, protein content of the body and bone mineral content. Disease activity was followed by the partial Mayo (pMayo) score. Statistical analysis was performed by paired t-test and Wilcoxon signed-rank test with SigmaPlot 1.25. Results The total of 22 patients (age: 44.4 ± 15.1 years, 6 male and 16 female patients) had received the 2-month budesonide-MMX therapy (2.0 ± 0.3 months). Mean disease duration was 8.3 years. By the end of follow-up, 15 (68.2%) patients experienced remission and 7 patients (31.8%) were primary non-responders. The disease activity decreased significantly from the mean of 3.95 to 1.64 (p < 0.001). No significant changes were observable in case of any body composition analysis parameter. Regarding the laboratory parameters, serum cholesterin level showed a significant increase (p < 0.001), while triglyceride and CRP showed did not show significant changes. Serum cortisol levels were elevated (p < 0.001), while PTH and DHEA showed no significant decrease. Only two patients experienced side effects: one of them hypertonia, headache and acnes, while the other patient experienced mild diarrhoea. One patient had a relapse during the treatment. Conclusion In our study, budesonide-MMX proved to be safe by bringing up a low number of side effects, while more than two-thirds of the patients could reach remission with this short-term therapy. Hormonal changes were not mentionable, although the drug’s effects on serum lipid content have to be examined further.

scholarly journals Body Composition in Women after Radical Mastectomy

2020 ◽  
Vol 17 (23) ◽  
pp. 8991
Author(s):  
Jacek Wilczyński ◽  
Piotr Sobolewski ◽  
Rafał Zieliński ◽  
Magdalena Kabała
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Body Composition ◽  
Fat Mass ◽  
Upper Limb ◽  
Radical Mastectomy ◽  
The Body ◽  
Control Group ◽  
Composition Analysis ◽  
Prevention And Treatment

The aim of the study was to analyse the body composition among women after radical mastectomy. The body compositions of 30 women after radical mastectomy (study group) were compared with those of 30 healthy females (control group). The method of electrical bioimpedance was used to analyse body composition. The significant differences between the groups, unfavourable for women, following mastectomy concerned body mass (p = 0.021), BMI (p = 0.049), fat mass (%) (p = 0.007), fat mass (kg) (p = 0.005), total body water (%) (p = 0.002), left upper limb fat mass (p = 0.013) as well as right upper limb fat mass (p = 0.022). The body composition of women after radical mastectomy was significantly worse compared to the control group. The majority of subjects were overweight and had high levels of body fat. Abnormal body composition is a modifiable risk factor of breast cancer; therefore, improving lifestyle is important in the prevention and treatment of this disease. There is a need for education, dietary supervision and physical activity in women following radical mastectomy. The innovation of our study was the use of the modern bioelectrical impedance analysis (BIA) method, which does not cause ionisation and is a gold standard in the field of body composition analysis. In future research, we plan to broaden the assessment of lifestyle and the significance of diet and physical activity in the prevention and treatment of breast cancer.

Child Growth and Health Studies in Oaxaca

1986 ◽  
Vol 8 (1-2) ◽  
pp. 13-15
Author(s):  
Robert Malina
Keyword(s):  
Body Composition ◽  
Body Size ◽  
Biological Activities ◽  
Child Growth ◽  
The Body ◽  
General Terms ◽  
Health Studies ◽  
Functional Complexity ◽  
Composition Changes

Growth and maturation are perhaps the basic biological activities which dominate the organism from conception to adulthood. Growth is viewed most often as increase in size of the entire organism or of its component parts, while maturation generally refers to the attainment of mature structure and/or function in specific systems of the body. In more general terms, as time passes during the first two decades of life, the child increases in body size, changes in bodily proportions and body composition, changes in functional complexity and matures. These dynamic functions characterize the growing years to the extent that the organism is constantly striving toward the adult or mature state, i.e., these processes are target-seeking or purposive.

Effects of Hydroxyurea Administration on the Body Weight, Body Composition and Exercise Performance of Patients with Sickle-Cell Anaemia

1997 ◽  
Vol 92 (5) ◽  
pp. 481-486 ◽  
Author(s):  
A. C. Hackney ◽  
W. Hezier ◽  
T. P. Gulledge ◽  
S. Jones ◽  
D. Strayhorn ◽  
...  
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Weight Gain ◽  
Sickle Cell ◽  
Sickle Cell Anaemia ◽  
The Body ◽  
Aerobic Performance ◽  
Composition Analysis ◽  
Anaerobic Performance ◽  
Significant Difference

1. As an ancillary study carried out during the recently completed Multicenter Study of Hydroxyurea, we examined the effect of hydroxyurea on the body weight, body composition and exercise capacity of adult patients with sickle-cell anaemia. 2. The subjects received either hydroxyurea (six males and four females) or placebo (eight males and six females). Data for each subject were generated during four separate 24 h admissions to the General Clinical Research Center. These admissions occurred at baseline and then at 6, 12 and 18 months after the start of study drug (hydroxyurea or placebo) administration. During each admission, body composition was measured by using a dual X-ray absorptiometer, and exercise testing was performed by cycle ergometry. Anaerobic performance was assessed according to a ‘Wingate’ protocol (20 s at maximal intensity against a cycling resistance of 7.5% body weight). Aerobic performance was examined using a steady state submaximal exercise protocol (10 min cycling time). 3. At baseline, no significant difference in any parameter was found between the hydroxyurea- and placebo-treated groups. At 18 months, the hydroxy-urea-treated subjects exhibited an average weight gain of 3.16 kg. The mean weight gain in the placebo-treated subjects was 1.82 kg. Body composition analysis showed that the additional weight in both groups involved both lean and fat body mass components. In anaerobic performance, the subjects given hydroxyurea showed an increase in peak muscle power of 104.9 W. The placebo group also showed an increase, but theirs was a more modest gain of 57.7 W. The most marked improvement in anaerobic performance was observed in the hydroxyurea-treated men (P < 0.05). In aerobic performance, the hydroxyurea-treated subjects exhibited a decrease in peak heart rate response to a standardized workload of 15.2 beats/min, as compared with a decrease of only 4.3 beats/min in the placebo-treated patients. 4. Taken together, the overall weight gain, combined with increases in both anaerobic muscular performance and aerobic cardiovascular efficiency, provides objective data to support the subjective impression that hydroxyurea administration produces an improvement in the physical capacity of patients with sickle-cell anaemia.

scholarly journals Body composition and Hashimoto disease

2021 ◽  
pp. 345-352
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Bioelectrical Impedance ◽  
Good Health ◽  
The Body ◽  
Composition Analysis ◽  
Tissue Water ◽  
Healthy Women ◽  
Hashimoto Disease

Background. Body weight or BMI do not provide any information about the content of muscle tissue, water content, body fat and its distribution in the body. Thyroid dysfunction is associated with a change in body weight, but also its composition regardless of physical activity. Objective. The aim of the study was to compare the body composition of female patients diagnosed with Hashimoto's disease (HD) and the body composition of healthy women who have never been treated before due to thyroid diseases. Materials and methods. The study involved 47 women diagnosed with Hashimoto disease (HD) and 65 women declaring good health. Body mass and height and body composition analysis using bioelectrical impedance analysis were performed using the TANITA multi-frequency segmental body composition analyzer. Variables having a distribution similar to the normal distribution were analyzed by the analysis of variance (ANOVA), otherwise the Kruskal-Wallis test was used. Results. Women with Hashimoto disease were characterized by significantly higher values of body weight, and thus BMI index, than healthy women (respectively 73.64 kg vs. 64.36 kg, p <0.0001; 27.65 kg/m2 vs. 23.95 kg/m2, p <0.001).The problem of excess body fat in the body statistically significantly more often affected women with Hashimoto disease than healthy women (44.7% vs. 13.8%, p <0.001). Conclusions. The results regarding the weight and composition of the patients treated for thyroid disease indicate the need for further in-depth analyses. Even small abnormalities of the thyroid function in the range of reference values may result in the development of many adverse changes in the body.

scholarly journals Assessment of the diet and body composition of students recreationally training team sports

2021 ◽  
Vol 13 (2) ◽  
pp. 47-54
Author(s):  
FILIP MICHAL BORYS ◽  
BEATA ZYSK ◽  
ADRIANNA ZANKO ◽  
DOMINIKA CHIMKOWSKA ◽  
JOANNA SMARKUSZ-ZARZECKA ◽  
...  
Keyword(s):  
Physical Activity ◽  
Vitamin D ◽  
Body Composition ◽  
Eating Behaviors ◽  
Team Sports ◽  
Dietary Supplementation ◽  
The Body ◽  
Composition Analysis ◽  
Study Group ◽  
Training Team

Background: Knowledge about nutrition and supplementation during increased physical activity is still insufficient among people recreationally training sports. The aim of the study was to assess the diet, supplementation and nutritional status, as well as to characterize the body composition of students who recreationally train team sports. Material and methods: T he study group consisted of 49 students from team sports sections (19 basketball, 10 volleyball and 20 football). The research tools used in the study were: a 24-hour nutritional interview, a questionnaire (concerning dietary supplementation, the frequency and duration of training) and the results of body composition analysis. Results: The students’ diets had insufficient energy value and deficiencies of EPA and DHA, carbohydrates, fiber and vitamin D. Excessive supply was related to: sodium, iron and vitamin C. 53% of the respondents declared dietary supplementation. Noteworthy, students whose trainings were longer more often decided to change their eating behaviors. Conclusions: The diet of the studied group was not properly balanced in terms of energy and some nutrients. The results of the assessment of students’ diets indicate the necessity of nutritional education for people undertaking regular physical activity.

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