scholarly journals Synthesis, structure, DNA binding and anticancer activity of a new tetranuclear Pb(II) complex constructed by 8-hydroxyquinolinate and 4-nitrobenzoate ligands

2019 ◽  
Vol 42 (1) ◽  
pp. 60-66
Author(s):  
Lu-Lu Lv ◽  
Wei-Min Xia ◽  
Yuan-Zheng Cheng ◽  
Li-Ping Zhang ◽  
Xue-Dong Wang
Keyword(s):  
Absorption Spectrum ◽  
Ir Spectroscopy ◽  
Single Crystal ◽  
Anticancer Activity ◽  
Tumor Cells ◽  
A549 Cell ◽  
Intrinsic Binding Constant ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Mcf 7

Abstract A new Pb(II) complex, [Pb(8-OQ)(4-NB)], where 8-OQ = 8-hydroxyquinolinate, 4-NB = 4-nitrobenzoate, has been synthesized and characterized by elemental analysis, IR spectroscopy, and X-ray single-crystal diffraction. The single crystal X-ray analysis reveals that the complex possesses a tetranuclear Pb4O4 cubane structure. The Pb(II) atom is coordinated by three triply bridging phenolic hydroxyl O atoms of 8-OQ ligands, then the tetranuclear Pb system is formed resulting in a tetrahedral cage. The interaction of complex with HS-DNA in Tris buffer was studied by UV−vis absorption spectrum and fluorescence ethidium bromide displacement experiment with an intrinsic binding constant of 1.52×104 M-1 and a linear Stern–Volmer quenching constant of 6.77×103 M-1. Anticancer activity against MCF-7, HepG-2 and A549 cell lines of complex was also determined by the MTT-based assay. The results showed the complex can inhibit proliferation of these three kinds of tumor cells and is less cytotoxic than cisplatin.

scholarly journals Synthesis, Characterization, Crystal Structure, and Biological Studies of a Cadmium(II) Complex with a Tridentate Ligand 4′-Chloro-2,2′:6′,2′′-Terpyridine

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
L. A. Saghatforoush ◽  
L. Valencia ◽  
F. Chalabian ◽  
Sh. Ghammamy
Keyword(s):  
Crystal Structure ◽  
Ir Spectroscopy ◽  
Single Crystal ◽  
Antibacterial Activities ◽  
Tridentate Ligand ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
H Nmr ◽  
Biological Studies ◽  
C Nmr

A new Cd(II) complex with the ligand 4′-chloro-2,2′6′,2′′-terpyridine (Cltpy), [Cd(Cltpy)(I)2], has been synthesized and characterized by CHN elemental analysis,1H-NMR,13C-NMR, and IR spectroscopy and structurally analyzed by X-ray single-crystal diffraction. The single-crystal X-ray analyses show that the coordination number in complex is five with three terpyridine (Cltpy) N-donor atoms and two iodine atoms. The antibacterial activities of Cltpy and its Cd(II) complex are tested against different bacteria.

scholarly journals A new oxygen-rich energetic salt dihydrazine tetranitroethide: a promising explosive alternative with high density and good performance

RSC Advances ◽  
2020 ◽  
Vol 10 (39) ◽  
pp. 23250-23253
Author(s):  
Haozheng Mei ◽  
Junqing Yang ◽  
Wenli Cao ◽  
Yong Hu ◽  
Piao He ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Ir Spectroscopy ◽  
Single Crystal ◽  
Elemental Analysis ◽  
High Energy ◽  
Oxygen Balance ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

A novel high-energy salt with good oxygen balance, dihydrazine tetranitroethide (5), has been synthesized and characterized by FT-IR spectroscopy, NMR spectroscopy, elemental analysis, and X-ray single crystal diffraction.

Short-range order in Li–Al tourmalines: IR spectroscopy, X-ray single crystal diffraction analysis and a bond valence theory approach

2019 ◽  
Vol 46 (9) ◽  
pp. 815-825 ◽  
Author(s):  
Yuliya Bronzova ◽  
Miriam Babushkina ◽  
Olga Frank-Kamenetskaya ◽  
Oleg Vereshchagin ◽  
Ira Rozhdestvenskaya ◽  
...  
Keyword(s):  
Ir Spectroscopy ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Short Range ◽  
Short Range Order ◽  
Bond Valence ◽  
Theory Approach ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Valence Theory

scholarly journals Environmentally Friendly Nafion-Catalyzed Synthesis of Substituted 2-Ethyl-3-Methylquinolines from Aniline and Propionaldehyde under Microwave Irradiation

Catalysts ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 877
Author(s):  
Chieh-Kai Chan ◽  
Chien-Yu Lai ◽  
Cheng-Chung Wang
Keyword(s):  
Reaction Mechanism ◽  
Microwave Irradiation ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Environmentally Friendly ◽  
Single Crystal Diffraction ◽  
X Ray ◽  
Related Data ◽  
Heating Source ◽  
Chemical Structures

Herein, we report a facile synthetic methodology for the preparation of 2,3-dialkylquinolines from anilines and propionaldehydes. This cyclization involved environmentally friendly Nafion® NR50 as an acidic catalyst with microwave irradiation as the heating source. A series of substituted 2-ethyl-3-methylquinolines were prepared from various anilines and propionaldehyde derivatives through this protocol with good to excellent yields. Some new chemical structures were confirmed by X-ray single-crystal diffraction analysis and the related data were provided. The plausible reaction mechanism studies are also discussed.

scholarly journals Structures, Chemical Conversions, and Cytotoxicity of Tricholopardins C and D, Two Tricholoma Triterpenoids from the Wild Mushroom Tricholoma pardinum

2021 ◽  
Author(s):  
Chen Shi ◽  
Yue-Ling Peng ◽  
Juan He ◽  
Zheng-Hui Li ◽  
Ji-Kai Liu ◽  
...  
Keyword(s):  
Hela Cell ◽  
Single Crystal ◽  
Cell Lines ◽  
Cell Apoptosis ◽  
Spectroscopic Methods ◽  
Wild Mushroom ◽  
X Ray Diffraction ◽  
X Ray ◽  
Hela Cell Lines ◽  
Mcf 7

AbstractTwo undescribed Tricholoma triterpenoids, namely tricholopardins C (1) and D (2), were isolated from the wild mushroom Tricholoma pardinum. Their structures with absolute configurations were elucidated by spectroscopic methods, as well as the single crystal X-ray diffraction. Compounds 1 and 2 were further obtained by chemical conversions from the known analogues. Compound 1 showed significant cytotoxicity to MCF-7 and Hela cell lines with IC50 values of 4.7 μM and 9.7 μM, respectively. Its mechanism of inducing MCF-7 cell apoptosis was studied briefly. Graphical Abstract

scholarly journals Synthesis, Structure, and Antiproliferative Activity of Three Gallium(III) Azole Complexes

2010 ◽  
Vol 2010 ◽  
pp. 1-10 ◽  
Author(s):  
Stergios Zanias ◽  
Giannis S. Papaefstathiou ◽  
Catherine P. Raptopoulou ◽  
Konstantinos T. Papazisis ◽  
Vasiliki Vala ◽  
...  
Keyword(s):  
Ir Spectroscopy ◽  
Single Crystal ◽  
Antiproliferative Activity ◽  
Bioinorganic Chemistry ◽  
Anionic Complex ◽  
X Ray ◽  
X Ray Crystallography ◽  
Mononuclear Complexes ◽  
Human And Mouse ◽  
Antiproliferative Activities

As part of our interest into the bioinorganic chemistry of gallium, gallium(III) complexes of the azole ligands 2,1,3-benzothiadiazole (btd), 1,2,3-benzotriazole (btaH), and 1-methyl-4,5-diphenylimidazole (L) have been isolated. Reaction of btaH or btd withGaBr3orGaCl3resulted in the mononuclear complexes[GaBr3(btaH)2](1) and[GaCl3(btd)2](2), respectively, while treatment ofGaCl3with L resulted in the anionic complex(LH)2[GaCl4](3). All three complexes were characterized by single-crystal X-ray crystallography and IR spectroscopy, while their antiproliferative activities were investigated against a series of human and mouse cancer cell lines.

Helical chain Ag(I) complexes with a tridentate N-donor ligand: syntheses, structural characterization, and properties

2015 ◽  
Vol 70 (12) ◽  
pp. 851-856 ◽  
Author(s):  
Chun-Hua Dai ◽  
Fu-Lin Mao
Keyword(s):  
Ir Spectroscopy ◽  
Single Crystal ◽  
Structural Characterization ◽  
Fluorescence Properties ◽  
Helical Chain ◽  
Donor Ligand ◽  
Thermogravimetric Analyses ◽  
X Ray

AbstractThe tridentate N-donor ligand 2,6-di(2-oxazolyl)pyridine (L) reacts with AgClO4 and AgPF6 to yield two new complexes, {[Ag5(L)5](ClO4)5}n (1) and {[Ag5(L)5](PF6)5}n (2), which have been characterized by single-crystal and powder X-ray diffractions, IR spectroscopy, and elemental and thermogravimetric analyses. Complexes 1 and 2 are isotypic, displaying helical chain structures. The fluorescence properties of 1 and 2 were investigated.

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