How does interface influence the level of analgesia when Virtual Reality distraction is used?

2014 ◽  
Vol 12 (1) ◽  
pp. 45-57 ◽  
Author(s):  
Joanna Piskorz ◽  
Marcin Czub ◽  
Katarzyna Urbańska ◽  
Małgorzata Mrula ◽  
Paweł Hodowaniec ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Undergraduate Students ◽  
Cold Water ◽  
Body Movement ◽  
Hand Movement ◽  
Cold Pressor Test ◽  
Analgesic Efficacy ◽  
Cold Pressor ◽  
Rotation Sensor ◽  
Significant Difference

Abstract This study investigates the effectiveness of virtual reality (VR) technology in distracting attention from pain. We tested how body engagement related to navigating the virtual environment (VE) influences the intensity of pain. Two different interfaces were used to play the same VE, and a cold pressor test was used for pain stimulation. A mixed design was used for the experiment. Sixty-six undergraduate students participated. One group navigated the game using a rotation sensor, head tracker and foot pedals (Body Movement Interface). Another group navigated only using their hands (Hand Movement Interface). Objective and subjective measures of pain were collected - the amount of time participants kept their hand in a container with cold water, and the participant’s assessment of the pain intensity on a visual analog scale (VAS). Participants also filled in questionnaires designed to measure feelings of presence in VE and emotional attitudes towards the game. We found no significant difference between the two used interfaces in their analgesic efficacy. In both groups during VR distraction, participants showed significantly higher levels of pain endurance than without VR distraction.

scholarly journals Thermovision Analysis Changes of Human Hand Surface Temperature in Cold Pressor Test

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Agnieszka Chwałczyńska ◽  
Katarzyna Gruszka ◽  
Ireneusz Całkosiński ◽  
Krzysztof A. Sobiech
Keyword(s):  
Surface Temperature ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Circulatory System ◽  
Cold Pressor ◽  
Human Hand ◽  
Average Weight ◽  
Pressor Test ◽  
Significant Difference ◽  
Before And After

The cold pressor test (CTP) as a diagnostic method of the circulatory system reactivity may be a basis for the qualification for thermal stimulation therapy. The aim of the work was a thermovisual assessment of the reaction to the Hines and Brown cold pressor test. A group of 30 healthy men in the age of 23.5 ± 0.8 years were examined. The average weight of the examinees was 78.4 ± 9.2 kg, their height 180.7 ± 5.9 cms, and BMI 23.9 ± 2.2 kg/m2. A thermovisual picture of a tested and not tested hand of all the subjects was taken before and after the cold pressor test. Under the influence of cold water the surface temperature of a tested hand has decreased in a statistically significant way by 8.3°C on average, which is 29% of the temperature before the test, whilst the temperature of an untested hand dropped by 0.67°C. The decreases of temperature were not even and there was a statistically significant difference between the dorsal and palmar side of the hand. The correlation between the changes of systolic blood pressure and the hand surface temperature before and after CTP was observed.

Influence of memory on experienced pain during Virtual Reality analgesia

2014 ◽  
Vol 12 (4) ◽  
pp. 41-52 ◽  
Author(s):  
Marcin Czub ◽  
Joanna Piskorz ◽  
Mateusz Misiewicz ◽  
Paweł Hodowaniec ◽  
Małgorzata Mrula ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Pain Intensity ◽  
Virtual Environments ◽  
Pain Treatment ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pain Tolerance ◽  
Intensity Measures ◽  
Pain Stimuli

Abstract Virtual Reality (VR) technology can be applied during pain treatment, acting as an effective distractor from pain stimuli. In our paper we investigate how memory influences experienced intensity of thermal pain stimuli. An experiment (within subject design) was conducted on 35 students from various Wroclaw universities. A cold pressor test was used for pain stimulation. Participants were immersed in customized virtual environments, created for this particular study. The environments differed at the level of memory engagement while playing a game. Pain measures were determined by the length of time participants kept their hands in cold water (pain tolerance), and their pain rating intensity was measured on the VAS scale (pain intensity). Participants were asked to put their hand in a container with cold water and keep it there until the pain became difficult to bear. In both VR conditions participants kept their hands in the cold water significantly longer than in a non-VR (control) condition. Results of pain intensity measures were in conclusive. We did not find any significant differences in effectiveness in the virtual environments that were used.

Distraction of attention with the use of virtual reality. Influence of the level of game complexity on the level of experienced pain

2014 ◽  
Vol 45 (4) ◽  
pp. 480-487 ◽  
Author(s):  
Joanna Piskorz ◽  
Marcin Czub
Keyword(s):  
Virtual Reality ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Low Complexity ◽  
Preliminary Evidence ◽  
Pain Tolerance ◽  
High Complexity ◽  
Thermal Pain ◽  
Lower Pain

Abstract : Research done in recent years shows that Virtual Reality (VR) can be an effective tool for distracting attention from pain. The purpose of this study was to test how the complexity of Virtual Environment (VE) influences the experienced intensity of thermal pain stimuli. A within-subjects design experiment was conducted, using cold pressor test for pain stimulation. Research was done on 31 students of Wroclaw Universities. Participants played games created for the purpose of the study, using head mounted displays and movement sensors. Two Virtual Environments differing in the level of complexity and non-VR control condition were used. The order of all conditions was counterbalanced. Participants reported significantly lower pain intensity (Visual Analogue Scale) after playing the high complexity game, compared to the low complexity game. There were also significant differences between non-VR control condition and high complexity game, but not between non-VR and low complexity game. The pain tolerance (measured by time of keeping the hand in cold water) was significantly higher in both VR conditions comparing to non-VR conditions. However, no significant differences between VE’s were found in pain tolerance ratings. Results of this study provide preliminary evidence that game complexity can be related to pain experience during VR interventions.

scholarly journals Role of Blood Pressure in Mediating Carotid Artery Dilation in Response to Sympathetic Stimulation in Healthy, Middle-Aged Individuals

2019 ◽  
Author(s):  
Arron Peace ◽  
Virginia Pinna ◽  
Friso Timmen ◽  
Guillherme Speretta ◽  
Helen Jones ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Carotid Artery ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Sympathetic Stimulation ◽  
Middle Aged ◽  
Cvd Risk ◽  
Significant Difference ◽  
History Of ◽  
Relative Change

Abstract Objectives Carotid artery diameter responses to sympathetic stimulation, i.e., carotid artery reactivity (CAR), represent a novel test of vascular health and relates to cardiovascular disease (CVD)/risk. This study aims to understand the relationship between the increase in blood pressure and carotid artery diameter response during the CAR-test in healthy, middle-aged men. Methods Sample consisted of 40 normotensive men (aged 31–59 years) with no history of CVD of currently taking medication. Noninvasive ultrasound was used to measure carotid artery diameter during the cold pressor test (CPT), with CAR% being calculated as the relative change from baseline (%). Mean arterial pressure (MAP) was measured with beat-to-beat blood pressure recording. Results CAR% was 4.4 ± 5.4%, peaking at 92 ± 43 seconds. MAP increased from 88 ± 9 mmHg to 110 ± 15 mmHg, peaked at 112 ± 38 seconds, which was significantly later than the diameter peak (P = 0.04). The correlation between resting MAP and CAR% was weak (r = 0.209 P = 0.197). Tertiles based on resting MAP or MAP-increase revealed no significant differences between groups in subject characteristics including age, body mass index, or CAR% (all P > 0.05). Subgroup analysis of individuals with carotid constriction (n = 6) vs. dilation (n = 34), revealed no significant difference in resting MAP or increase in MAP (P = 0.209 and 0.272, respectively). Conclusion Our data suggest that the characteristic increase in MAP during the CPT does not mediate carotid artery vasomotion.

scholarly journals 0233 Pain, Fatigue, and Altered Reactivity to a Repeated Physiological Stressor in Insomnia Patients: An Explanatory-Driven Analysis

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A90-A90
Author(s):  
M R Goldstein ◽  
J K Devine ◽  
R Dang ◽  
B Chatterton ◽  
J Scott-Sutherland ◽  
...  
Keyword(s):  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Comprehensive Treatment ◽  
Spontaneous Pain ◽  
Science Center ◽  
Female Age ◽  
Complex Relationships ◽  
Physiological Stressor ◽  
Pain Testing

Abstract Introduction Fatigue and pain are prominent features of functional impairment in insomnia. This study aimed to better understand behavioral and physiological mechanisms of these complex relationships. Methods 22 participants with insomnia disorder (DSM-5 criteria, 18 female, age 18-49yrs) and 22 good-sleeper controls (19 female, age 18-47yrs) completed two-weeks sleep logs and actigraphy recordings prior to coming to the laboratory for overnight polysomnography and subsequent daytime testing that included questionnaires, three trials of cold pressor test (CPT), and pain testing with blood draws collected throughout. Insomnia diagnosis was determined by a board-certified sleep specialist, and exclusion criteria included psychiatric history within past 6 months, other sleep disorder, significant medical conditions, and any medications within past two weeks with significant effects on inflammation, autonomic function, or other psychotropic effects. For CPT, participants were instructed to immerse hand in ice cold water for at least one minute and rate pain intensity throughout the immersion and 3-minute recovery. Data were analyzed with linear mixed models. Results Per inclusion criteria, PSQI scores were differed between groups (insomnia: 10.2±2.7, range 7–16; control: 1.9±1.3, range 0–5; p<.001). Insomnia consistently reported higher daily fatigue ratings compared to controls (p<.001), as well as higher spontaneous pain globally and across several specific domains (p’s: .007-.03). In response to CPT, groups did not differ in their initial tolerance (i.e. immersion duration, p=.41) or intensity ratings during immersion (p=.88), however insomnia showed blunted recovery in intensity ratings (p<.01). Control participants then showed an ability to habituate to repeated CPT by increasing immersion duration, whereas insomnia slightly decreased in tolerance across trials (Group effect: p<.05). Conclusion These data indicate that habituation to and acute recovery from pain is deteriorated in chronic insomnia, which may be a key contributor to maintained pathophysiology over time and mechanism to target with comprehensive treatment. Support Merck Inc. MISP# 51971 (investigator-initiated), NIH/National Center for Research Resources UL1-RR02758 and M01-RR01032 to the Harvard Clinical and Translational Science Center.

scholarly journals Are Cognitive Load and Focus of Attention Differentially Involved in Pain Management: An Experimental Study Using a Cold Pressor Test and Virtual Reality

2020 ◽  
Vol Volume 13 ◽  
pp. 2213-2222 ◽  
Author(s):  
Stéphanie Dumoulin ◽  
Stéphane Bouchard ◽  
Claudie Loranger ◽  
Pamela Quintana ◽  
Véronique Gougeon ◽  
...  
Keyword(s):  
Experimental Study ◽  
Virtual Reality ◽  
Pain Management ◽  
Cognitive Load ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Focus Of Attention ◽  
Pressor Test

Differential pain modulation in patients with peripheral neuropathic pain and fibromyalgia

2012 ◽  
Vol 3 (3) ◽  
pp. 116-123 ◽  
Author(s):  
Lise Gormsen ◽  
Flemming W. Bach ◽  
Raben Rosenberg ◽  
Troels S. Jensen
Keyword(s):  
Neuropathic Pain ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Pain Modulation ◽  
Pain Tolerance ◽  
Spontaneous Pain ◽  
Peripheral Neuropathic Pain ◽  
Pressor Test ◽  
Pain Patients

AbstractBackgroundThe definition of neuropathic pain has recently been changed by the International Association for the Study of Pain. This means that conditions such as fibromyalgia cannot, as sometimes discussed, be included in the neuropathic pain conditions. However, fibromyalgia and peripheral neuropathic pain share common clinical features such as spontaneous pain and hypersensitivity to external stimuli. Therefore, it is of interest to directly compare the conditions.Material and methodsIn this study we directly compared the pain modulation in neuropathic pain versus fibromyalgia by recording responses to a cold pressor test in 30 patients with peripheral neuropathic pain, 28 patients with fibromyalgia, and 26 pain-free age-and gender-matched healthy controls. Patients were asked to rate their spontaneous pain on a visual analog scale (VAS (0–100 mm) immediately before and immediately after the cold pressor test. Furthermore the duration (s) of extremity immersion in cold water was used as a measure of the pain tolerance threshold, and the perceived pain intensity at pain tolerance on the VAS was recorded on the extremity in the water after the cold pressor test. In addition, thermal (thermo tester) and mechanical stimuli (pressure algometer) were used to determine sensory detection, pain detection, and pain tolerance thresholds in different body parts. All sensory tests were done by the same examiner, in the same room, and with each subject in a supine position. The sequence of examinations was the following: (1) reaction time, (2) pressure thresholds, (3) thermal thresholds, and (4) cold pressor test. Reaction time was measured to ensure that psychomotoric inhibitions did not influence pain thresholds.ResultsPain modulation induced by a cold pressor test reduced spontaneous pain by 40% on average in neuropathic pain patients, but increased spontaneous pain by 2.6% in fibromyalgia patients. This difference between fibromyalgia and neuropathic pain patients was significant (P < 0.002). Fibromyalgia patients withdrew their extremity from the cold water significantly earlier than neuropathic pain patients and healthy controls; however, they had a higher perceived pain intensity on the VAS than neuropathic pain patients and control subjects. Furthermore, neuropathic pain patients had a localized hypersensitivity to mechanical and thermal stimuli in the affected area of the body. In contrast, fibromyalgia patients displayed a general hypersensitivity to mechanical and thermal stimuli when the stimuli were rated by the VAS, and hypersensitivity to some of the sensory stimuli.ConclusionsThese findings are the first to suggest that a conditioning stimulus evoked by a cold pressor test reduced spontaneous ongoing pain in patients with peripheral neuropathic pain, but not in fibromyalgia patients when directly compared. The current study supports the notion that fibromyalgia and neuropathic pain are distinct pain conditions with separate sensory patterns and dysfunctions in pain-modulating networks. Fibromyalgia should therefore not, as sometimes discussed, be included in NP conditions.ImplicationsOn the basis of the findings, it is of interest to speculate on the underlying mechanisms. The results are consistent with the idea that peripheral neuropathic pain is primarily driven from damaged nerve endings in the periphery, while chronic fibromyalgia pain may be a central disorder with increased activity in pain-facilitating systems.

Comparison of Virtual Reality Visualizations With Traditional Visualizations in Hotel Settings

2020 ◽  
pp. 109634802095706
Author(s):  
Lisa Slevitch ◽  
Tilanka Chandrasekera ◽  
Meghan Drew Sealy
Keyword(s):  
Virtual Reality ◽  
Undergraduate Students ◽  
Small Sample Size ◽  
Research Question ◽  
Nonparametric Tests ◽  
Small Sample ◽  
South Central ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Time Periods

The objective of the current study was to investigate how virtual reality (VR) visualizations compare with traditional visualizations such as two-dimensional (2D) photos as a marketing tool for hotel websites. The specific research question was “How do VR visualizations compare with 2D photos in terms of (1) affective responses, (2) attitudinal/behavioral responses, and (3) cognitive load—that is, task efforts and experiences associated with technology?” A quasi-experimental study was conducted over two time periods with independent sample pools. A boutique hotel lobby and a guest room were captured in 2D and VR formats. Subjects were randomly assigned to one of the two types of visualizations. The sample comprised 84 university undergraduate students from the South-Central United States. Nonparametric tests were used to test the proposed hypotheses. There was a statistically significant difference between two visual conditions for several variables—that is, pleasure, satisfaction, word of mouth, and so on. However, those differences were not always consistent between the two time periods. Overall findings suggest that the use of VR visualizations as a promotional tool might not be more effective than traditional photos. Limitations of the study include using students as a proxy for the general population of travelers, small sample size, self-reported measures, and narrow conditional scope. Those limitations should be addressed in future studies.

scholarly journals Effects of Cold Stimulation Induced Pain on Cardiopulmonary Parameters: A Gender Based Study

2020 ◽  
Vol 18 (1) ◽  
pp. 15-18
Author(s):  
R.K. Jha ◽  
S. Amatya
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Respiratory Rate ◽  
Acute Pain ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Cold Stimulation ◽  
Cross Sectional ◽  
Pressor Test

Background Cold pressor induced pain elicits sympathetic responses which can be monitored by measuring blood pressure, heart rate and respiratory rate after exposure to the cold stress. Objective This study was done to evaluate gender difference in acute pain induced by cold pressor test on blood pressure, heart rate and respiratory rate of healthy individuals. Method Our study was cross sectional study with the sample size of 40 including 20 male and 20 female undergraduates. Acute pain was induced by immersion of hand in cold water at 4°C. Changes in blood pressure, heart rate and respiratory rate were recorded by the digital sphygmomanometer and AD Instruments (Model: ML856, Serial: T26-4025) and analysis was done by Lab Chart 7 Pro v 7.3.3 respectively. Acute pain parameter like pain threshold was also recorded. Statistical analysis was done by using Paired “t” test and non-parametric test. Result The present study enrolled 40 participants, aged between 18 – 24 years, and body mass index from 15.78 – 36.06 kg/m2. The respiratory rate was increased in both males (17.30±3.19 to 19.0±3.21, P=0.01) and females (18.60±1.98 to 19.90±2.82, P= 0.01) however significant increase in heart rate was only found in females (77.80±8.07 to 80.70±7.80, P=0.03) after cold pressor test. The systolic as well as diastolic blood pressure did not increase significantly after cold pressor test. The pain thresholds ranged from 25.2 to 105.8 seconds (61.60±23.26, male Vs. 52.69±18.49, female, p = 0.188). Conclusion Our findings point towards autonomic adjustments suggesting more of sympathetic over activity immediately after cold pressor test.

scholarly journals A social and physical stressor increases later punishment in healthy males

2021 ◽  
Author(s):  
Yacila Isabela Deza-Araujo ◽  
Ulrike Rimmele ◽  
Lucien Gyger ◽  
Cora Aguirre ◽  
David Sander ◽  
...  
Keyword(s):  
Social Interactions ◽  
Cold Water ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Social Contexts ◽  
Control Procedure ◽  
Water Test ◽  
Individual Variables ◽  
The Impact

Existing literature suggests that stress in early life can influence or trigger later aggressive and punishment behaviors during social interactions. However, only a few human studies have addressed this link in controlled experimental settings. Here, we assessed the impact of biological and behavioral markers of stress on economic and social interactions in healthy men using a between-group design. The Socially Evaluated Cold Pressor Test (i.e., supervised hand immersion into cold water) was applied to one group of participants (n = 19), while a second group underwent the Warm Water Test (n = 21). After the stressor or control procedure, all participants played the Inequality Game, a paradigm in which they could engage in punishment, cooperative, or aggressive behaviors towards a fair and an unfair counterpart player. Compared to the control condition, participants in the stress condition engaged in more punishment behaviors towards the unfair player and less cooperative behaviors towards both players. Critically, higher levels of cortisol in the stress group were associated with more punishment behaviors towards the unfair player. In contrast, aggressive behavior did not differ between participants in the stress vs. control condition. Overall, our findings showed that situationally induced stress might facilitate punishment behaviors in provoking situations. Further research should elucidate the role of inter-individual variables that may encourage or prevent stress-related punishment in social contexts.

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