scholarly journals Effect of micro osteo-perforations (MOP) on the rate of tooth movement and levels of interleukin-1β - a split mouth study

2021 ◽  
Author(s):  
Venkata Naidu Bavikati ◽  
Abdul Rasheed Muhameed ◽  
Nikitha Mohaley ◽  
Manjula K. Thimmaiah ◽  
Keerthi Kavya Botlagunta ◽  
...  
Keyword(s):  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Chemical Interaction ◽  
Invasive Procedure ◽  
Interleukin 1Β ◽  
Success Rates ◽  
Canine Retraction ◽  
Significant Difference ◽  
The Individual ◽  
The Right

Introduction. Various procedures are available today to enhance tooth movement, with relative success rates, one among them being Micro Osteo Perforation (MOP). Our aim is to assess the rate of tooth movement and interleukin 1β levels in gingival crevicular fluid levels (GCF)after MOPs. Methodology. A group of 22 patients were selected, who required first premolars extraction  and were designated for the split mouth study with equal allocation. MOP was performed on the right side, three vertical MOPs were given using 1.2 X 8 mm mini implants with the gap of 2 mm between them and surgical depth of the implant insertion was 5 mm. The left side was used as control. The individual canine retraction was initiated with placement of 150 grams on 19*25 SS wire. The case was evaluated at different timelines for canine retraction and Interleukin 1β levels. Results. There was a significant difference in the rate of canine movement at 45 days (1.42 mm) and end of canine retraction on experimental side(2.61 mm). The GCF levels were raised at T1 and T2 intervals on the side of MOP and were statically significant (p=0.00). Conclusion. MOP is a minimally invasive procedure which accelerates the tooth movement by 20%. The increase in IL 1βlevels indicates a higher rate of chemical interaction on the surgically assisted side. For enhanced efficiency MOPs should be repeated every 6-8 weeks.

scholarly journals Leptin levels in gingival crevicular fluid during canine retraction: in vivo comparative study

2019 ◽  
Vol 46 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Sanjit Kumar Sar ◽  
Divya Shetty ◽  
Piush Kumar ◽  
Saurabh Juneja ◽  
Payal Sharma
Keyword(s):  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Nickel Titanium ◽  
Coil Spring ◽  
Canine Retraction ◽  
Space Closure ◽  
Significant Difference ◽  
Elisa Technique ◽  
Crevicular Fluid

Objective: To evaluate and compare the leptin levels in gingival crevicular fluid (GCF) and rate of canine retraction using an elastomeric chain and nickel–titanium (NiTi) closed coil spring. Design: In vivo, clinical study. Setting: Orthodontic department at ITS Centre for Dental Studies and Research, Ghaziabad, India. Participants: Twenty-seven patients reported to the Department of Orthodontics at ITS Centre for Dental Studies and Research. Methods: Twenty-seven patients were included in the study in which canine retraction was carried out with an elastomeric chain and NiTi closed coil spring on either side of the arch applying 150 g of force on both sides. GCF samples were collected before the commencement of canine retraction, on the first, seventh and 21st day after application of force and were analysed for leptin levels by the ELISA technique. Impressions for the study model were taken at baseline and after 21 days to measure the rate of tooth movement bilaterally with an electronic digital calliper. Results: The results obtained within both groups showed a significant decrease in leptin levels from baseline to 21 days ( P = 0.0001). There was no significant difference in leptin levels between both groups, but leptin levels decreased more in the NiTi closed coil spring group. The rate of tooth movement is not significantly different between both groups, but space closure is faster in the NiTi closed coil spring group. Conclusions: Leptin levels in GCF showed a significant decrease during canine retraction using an elastomeric chain and NiTi coil spring; there was no significant difference in the rate of tooth movement between both the groups.

scholarly journals Effect of ovarian activity on orthodontic tooth movement and gingival crevicular fluid levels of interleukin-1β and prostaglandin E2 in cats

2012 ◽  
Vol 83 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Ahmet Arif Celebi ◽  
Serhat Demirer ◽  
Bulent Catalbas ◽  
Sevket Arikan
Keyword(s):  
Prostaglandin E2 ◽  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Orthodontic Tooth Movement ◽  
Interleukin 1Β ◽  
Enzyme Linked Immunosorbent Assay ◽  
Ovarian Activity ◽  
Coil Spring ◽  
Significant Difference ◽  
Crevicular Fluid

Abstract Objective: To evaluate whether there is any correlation between ovarian activity and two potent bone-resorbing mediators (prostaglandin E2 [PGE2], interleukin-1β [IL-1β]) secreted from the gingival crevicular fluid (GCF) during orthodontic tooth movement. Materials and Methods: Eighteen female cats were included in this study. Animals were randomly divided into three groups (estrous, anestrous, and ovariectomized groups), each having six queens. Estrous was induced by administration of 150 IU equine chorionic gonadotropin (eCG) to queens of the estrous group. A closed-coil spring, applied with 80 g of tipping force to the canine, was attached between the maxillary canine and mini-implant. GCF was collected on days 0, 6, and 12 from each cat to examine PGE2 and IL-1β during orthodontic tooth movement in cats. The PGE2 and IL-1β levels were determined with enzyme-linked immunosorbent assay. Results: There was no significant difference (P > .05) between anestrous and the ovariectomized groups in terms of tooth movement on days 6 and 12 of distalization. In contrast, tooth movement in the estrous group was lower (P < .05) than in the remaining two groups (anestrous and ovariectomized). The mean PGE2 and IL-1β levels of the canine teeth of the estrous groups were significantly lower than the remaining two groups on days 6 and 12 (P < .05) of coil spring applications. Conclusions: These results indicate that ovarian activity can affect orthodontic tooth movement and GCF levels of IL-1β and PGE2 in cats.

scholarly journals Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement

2021 ◽  
Vol 10 (7) ◽  
pp. 1405
Author(s):  
Fabrizia d’Apuzzo ◽  
Ludovica Nucci ◽  
Ines Delfino ◽  
Marianna Portaccio ◽  
Giuseppe Minervini ◽  
...  
Keyword(s):  
Periodontal Ligament ◽  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Orthodontic Tooth Movement ◽  
High Sensitivity ◽  
Data Analysis Procedure ◽  
Vibrational Spectroscopies ◽  
Composition Structure ◽  
The Individual ◽  
Crevicular Fluid

Optical vibrational techniques show a high potentiality in many biomedical fields for their characteristics of high sensitivity in revealing detailed information on composition, structure, and molecular interaction with reduced analysis time. In the last years, we have used these techniques for investigating gingival crevicular fluid (GCF) and periodontal ligament (PDL) during orthodontic tooth treatment. The analysis with Raman and infrared signals of GCF and PDL samples highlighted that different days of orthodontic force application causes modifications in the molecular secondary structure at specific wavenumbers related to the Amide I, Amide III, CH deformation, and CH3/CH2. In the present review, we report the most relevant results and a brief description of the experimental techniques and data analysis procedure in order to evidence that the vibrational spectroscopies could be a potential useful tool for an immediate monitoring of the individual patient’s response to the orthodontic tooth movement, aiming to more personalized treatment reducing any side effects.

scholarly journals Effect of platelet-rich plasma on the rate of orthodontic tooth movement:

2020 ◽  
Vol 90 (3) ◽  
pp. 354-361 ◽  
Author(s):  
Ahmed El-Timamy ◽  
Fouad El Sharaby ◽  
Faten Eid ◽  
Amr El Dakroury ◽  
Yehya Mostafa ◽  
...  
Keyword(s):  
Tooth Movement ◽  
Platelet Rich Plasma ◽  
Orthodontic Tooth Movement ◽  
The Other ◽  
Positive Potential ◽  
Canine Retraction ◽  
Steady Rate ◽  
Significant Difference ◽  
To Receive ◽  
Retraction Force

ABSTRACT Objective To investigate the effect of local injection of platelet-rich plasma (PRP) on the rate of orthodontic tooth movement. Materials and Methods Sixteen female patients were randomly allocated in a split-mouth study design to receive PRP injections with CaCl2 activating solution on one side (intervention side) while the other side received CaCl2 injection only (control side). Canine retraction was performed on 0.017 × 0.025-inch stainless steel archwire applying 1.5 N retraction force. PRP and CaCl2 injections were done at 0, 3, and 6 weeks. The duration of the study was 4 months. Data were collected from digitized models. Assessment of pain accompanying the procedure was done using a visual analogue scale. Results The rate of canine retraction was faster on the intervention side in the first 2 months, with a statistically significant difference in the first month (P = .049). On the other hand, the rate was statistically significantly slower on the intervention side in the third month following cessation of PRP injections (P = .02). Pain increased following injections on both sides. Conclusions PRP showed a positive potential to accelerate the rate of tooth movement when injected in the first 2 months. Repeated injections of PRP to maintain a steady rate of accelerated tooth movement warrant further investigation.

scholarly journals Comparison of Rate of Canine Retraction and Secondary Outcomes Associated With Conventional Fixed Orthodontic Treatment and Minimally Invasive Techniques (MOPs): A Randomized Control Trial

2020 ◽  
pp. 030157422096350
Author(s):  
Ajit Vikram Parihar ◽  
Shivam Verma ◽  
TP Chaturvedi ◽  
Naresh Kumar ◽  
A Kavin Prasanth ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Root Resorption ◽  
Control Group ◽  
P Value ◽  
Pain Level ◽  
Canine Retraction ◽  
Significant Difference ◽  
Secondary Outcomes ◽  
Anchorage Loss

Introduction: The objective of the study was to assess the rate of canine retraction and secondary outcomes associated with conventional fixed orthodontic treatment (CFO) and CFO with micro-osteoperforation (CFO + MOP), that is, anchorage loss, root resorption, vitality of tooth, pain and discomfort level during the procedure. Methods: A total of 16 patients with Class II Division 1 malocclusion who required upper first premolar extraction with lower non-extraction/single incisor extraction were divided into the test group (MOP) and positive control group (CFO + MOP) for a split-mouth study. Both maxillary canines were retracted with nickel–titanium (NiTi) closed coil springs. Patients were reviewed after 24 hours, 7 days, 28 days, and 4, 8, and 16 weeks to assess the rate of tooth movement, anchorage loss, root resorption, vitality of tooth, pain and discomfort level. Results: There was a statistically significant difference in the rate of tooth movement between the CFO and CFO + MOP groups after the first 4 weeks ( P-value = .026), whereas no statistically significant difference was observed at 8, 12, and 16 weeks ( P-value = .33, .99, and .08, respectively). In the CFO group, there was no statistically significant difference in tooth movement between different time intervals ( P-value > .05). There was no significant difference in root resorption between the groups. The pain level was higher in the MOP group in the first 24 hours ( P-value < .05) after the procedure. Later on, the difference in pain level between the groups was not significant ( P-value > .05). The vitality of retracted canines in both groups was healthy. Conclusion: The study recommends that the CFO + MOP procedure has substantial potential to be used as an adjunct to the routine mechanotherapy for faster tooth movement, as it may reduce the treatment time by half in the first 4 weeks after the MOP procedure. There are no potential differences in anchorage loss, tipping, vitality, and apical and lateral root resorption between the CFO and CFO + MOP groups. This trial was registered at Clinical Trial Registry, India.

scholarly journals Location of accessory pathways and its radiofrequency ablation in Wolf-Parkinson-White syndrome

2006 ◽  
Vol 134 (9-10) ◽  
pp. 386-392 ◽  
Author(s):  
Dejan Vukajlovic ◽  
Lazar Angelkov ◽  
Aleksandar Neskovic
Keyword(s):  
Radiofrequency Ablation ◽  
Interface Temperature ◽  
Success Rates ◽  
Recurrence Rates ◽  
Accessory Pathways ◽  
First Line Therapy ◽  
Total Procedure Time ◽  
Significant Difference ◽  
Primary Success ◽  
The Right

Introduction: Radiofrequency ablation (RFA) of accessory pathways (AP) is the first line therapy in symptomatic patients with preexcitation syndrome, resistant to medical therapy. Objective: To evaluate the influence of AP location on RFA effectiveness. Method: The study compared RFA results of AP located on the left side, right side, and in septal area of the heart in the first 101 consecutive patients treated at Dedinje Cardiovascular Institute in Belgrade. Results: There was no significant difference between the right-, left- and septal-AP in relation to primary success rates (66.7%, 84.3%, 73.7%, respectively, p=0.285), recurrence rates (12.5%, 6.97%,14.3%, p=0.591), and final success rates (66%, 84.3%, 78.9%, p=0.37). Maximally achieved interface temperature was lowest at right-sided AP (49.8?1.9?C) as compared to the left (53.0?3.5?C) or septal AP (52.9?3.0?C) (p<0.01). Fluoroscopy time did not differ significantly (p=0.062), while total procedure time and the number of applied RF pulses was higher in the left-sided AP as compared to other two (104.6?44.9 for the left, 98.9?47.5 for the right and 80.7?39.8 minutes for the septal AP, p<0.05; 11.0?8.8 pulses for the left, 6.5?3.8 for the right and 6.4?5.0 for septal AP, p<0.01). Two major complications developed: one third-degree AV block after ablation of midseptal AP, and one pericardial effusion without tamponade, with spontaneous regression. Conclusion: The success rate of RFA of the right-, left- and septal-AP was similar. Heating of the tissue was weakest during RFA of the right-sided AP.

scholarly journals Pentraxin-3 Levels in Gingival Crevicular Fluid during Canine Retraction with Nickel–Titanium Coil Spring and Active Tieback

2017 ◽  
Vol 18 (8) ◽  
pp. 710-713
Author(s):  
Sukhpreet Mangat ◽  
Rakesh Thukral ◽  
Anvesha Ganguly ◽  
Harleen Bali ◽  
Shekhar Grover
Keyword(s):  
Orthodontic Treatment ◽  
Gingival Crevicular Fluid ◽  
Nickel Titanium ◽  
Enzyme Linked Immunosorbent Assay ◽  
Pentraxin 3 ◽  
Coil Spring ◽  
Time Intervals ◽  
Canine Retraction ◽  
Significant Difference ◽  
Crevicular Fluid

ABSTRACT Aim Orthodontic treatment is routinely carried out in patients with the purpose of correcting various forms of dental malocclusions. Retraction of the canines can be achieved either individually or along with incisor. Pentraxin-3 (PTX-3) is regarded as the true independent indicator of disease activity. Hence, we undertook the present study to assess and compare the level of PTX-3 in patients undergoing canine retraction with active tieback and Nickel–Titanium (NiTi) coil spring. Materials and methods The present study included assessment of 25 patients that underwent canine retraction as a part of fixed orthodontic treatment. In the maxillary right and left quadrant, active tieback and NiTi coil spring were used respectively. Gingival crevicular fluid samples were collected 1 hour prior to the commencement of orthodontic canine retraction procedure followed by collection at following time intervals: 1 hour, 1, 7, and 14 days after the start of canine retraction procedure. Enzyme-linked immunosorbent assay kit was used for analysis of the samples as per manufacturer's instructions. All the data were recorded and compiled. All the results were analyzed by Statistical Package for the Social Sciences software. Results Nonsignificant difference was observed in the values of PTX-3 at baseline and 1 hour. While comparing the mean PTX-3 values between different time intervals in both the study groups, significant difference was observed. Conclusion In comparison to the active tieback, NiTi coil exhibited faster space closure rate. Clinical significance In patients undergoing orthodontic treatment, PTX-3 is associated with periodontal remodeling under the effect of orthodontic forces. How to cite this article Thukral R, Mangat S, Ganguly A, Agarkar SS, Bali H, Grover S. Pentraxin-3 Levels in Gingival Crevicular Fluid during Canine Retraction with Nickel–Titanium Coil Spring and Active Tieback. J Contemp Dent Pract 2017; 18(8):710-713.

scholarly journals Analysis of the coracoid morphology with multiplanar 2D CT and its effects on the graft size in the Latarjet procedure

2020 ◽  
Vol 28 (3) ◽  
pp. 230949902096460
Author(s):  
Abdulkadir Sarı ◽  
Hadi Sasani ◽  
Mehmet Ümit Çetin ◽  
Burak Günaydin ◽  
Seyran Kilinç ◽  
...  
Keyword(s):  
Reconstruction Method ◽  
Dominant Hand ◽  
Dominant Group ◽  
Positive Correlation ◽  
Left Hand ◽  
Computed Tomography Images ◽  
Significant Difference ◽  
Defect Repair ◽  
The Individual ◽  
The Right

Purpose: In this study, we aimed to reveal the individual differences regarding the size of the coracoid and their effects on the classical and modified Latarjet procedures. Methods: Computed tomography images of 120 patients (mean age: 41.18 ± 12.01 years) without shoulder complaints or shoulder instability were evaluated retrospectively. The glenoid width, the surgical graft length, and the coracoid total length, width, and thickness were measured using the multiplanar reconstruction method on the Sectra Picture Archiving and Communications System (PACS) system. Age, gender, side, the dominant hand, and the height of the patients were recorded and the correlations between them were investigated. On the created hypothetical model, the current size of the coracoid was evaluated to determine what size of glenoid defects it could repair by employing the classical and the modified Latarjet techniques. Results: There was no significant difference between the right-hand-dominant group and the left-hand-dominant group in terms of coracoid measurement results ( p > 0.05). Again, there was no statistically significant difference between the right and the left side regarding the coracoid size ( p > 0.05). A positive correlation could be detected only between age and the coracoid width and thickness ( p < 0.05). A positive correlation was also found between the glenoid width and the coracoid width and thickness in both shoulders ( p < 0.001). Coracoid thickness could fill in the defects that amounted to 40% of the glenoid width, while the coracoid width could fill in for the defects that were 50% of the glenoid width in both genders. Conclusion: Our study showed that hand dominance and side were not effective on the coracoid dimensions. In addition, it has been shown that the coracoid dimensions did not have a significant effect in the choice of Latarjet technique in terms of defect repair and that repair rates of up to 40% could be achieved in glenoid defects with both techniques.

scholarly journals Interleukin 1β Levels around Microscrew Implants during Orthodontic Tooth Movement

2007 ◽  
Vol 77 (6) ◽  
pp. 1073-1078 ◽  
Author(s):  
Emel Sarı ◽  
Cihan Uçar
Keyword(s):  
Treatment Group ◽  
Alveolar Bone ◽  
Tooth Movement ◽  
Gingival Crevicular Fluid ◽  
Orthodontic Tooth Movement ◽  
Experimental Period ◽  
Interleukin 1Β ◽  
Implant Placement ◽  
The Mean ◽  
Crevicular Fluid

Abstract Objective: To determine whether interleukin 1β (IL-1β) levels are elevated around microscrew implants that are used as anchorage for tooth movement. Materials and Methods: Ten young adults, aged 16.3 ± 2.5 years and with all four premolars extracted , comprised the study group. Twenty maxillary microscrew implants were placed bilaterally in the alveolar bone between the maxillary second premolars and first molars as anchorage units for distal movement of the maxillary canines. The maxillary canines served as the treatment group, and the microscrew implants were designated as the implant group. The mandibular canines were used as controls. Peri-microscrew implant crevicular fluid (MICF) and gingival crevicular fluid (GCF) were collected at the beginning of tooth movement (2 weeks after implant placement); at 24, 48, and 168 hours later; and on days 14 and 21. An automated enzyme immunoassay was used to measure 1L-1β in the MICF and the GCF. Results: The mean 1L-1β level in the treatment group was significantly elevated at 24 hours (P = .003 &lt; .05) and 48 hours (P = .003 &lt; .05), whereas the levels in the control and implant groups did not change significantly during the experimental period. Also, the mean 1L-1β level of the treatment group was significantly higher that in both the control and implant groups at 24 and 48 hours. Conclusions: The microscrew implants did not demonstrate increased 1L-1β levels during tooth movement. This supports the concept that microscrew implants might be useful as absolute anchorage devices.

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