The Relationship Between Head Circumference and the Development of Communicating Hydrocephalus in Infants Following Intraventricular Hemorrhage

PEDIATRICS ◽  
1975 ◽  
Vol 56 (1) ◽  
pp. 74-77 ◽  
Author(s):  
Rowena Korobkin
Keyword(s):  
Clinical Sign ◽  
Premature Infants ◽  
Gestational Age ◽  
Head Circumference ◽  
Intraventricular Hemorrhage ◽  
Clinical Status ◽  
Clinical Deterioration ◽  
Communicating Hydrocephalus ◽  
Sudden Appearance ◽  
The Relationship

Rapidly enlarging head circumference is a standard clinical sign of progressive hydrocephalus in an infant. Six neonates 29 to 36 weeks gestational age, with intraventricular hemorrhage, confirmed by ventricular tap, had head circumferences measured at intervals from birth. The sudden appearance of rapidly expanding head size, not associated with changing clinical status, occurred 9 to 20 days after the estimated time of hemorrhage in all of the infants. Air ventriculography within three days of abnormal acceleration of head circumference growth demonstrated moderately to severely dilated ventricles. The ventricles were probably enlarging slowing from the time of hemorrhage because there was no associated clinical deterioration in the infants coincident with the rapid increase in head circumference. After intraventncular hemorrhage, enlarging head circumference appears to be an insensitive sign of hydrocephalus in premature infants.

scholarly journals Investigation of the relationship between umbilical cord pH and intraventricular hemorrhage of infants delivered preterm

2019 ◽  
Vol 65 (5) ◽  
pp. 647-656
Author(s):  
Ali Mazouri ◽  
Mahtab Massahi ◽  
Nasrin Khalesi ◽  
Ladan Younesi asl ◽  
Mandana Kashaki
Keyword(s):  
Umbilical Cord ◽  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Neonatal Intensive Care ◽  
Blood Gases ◽  
Blood Gas ◽  
The Third ◽  
The Relationship ◽  
Type Of Delivery ◽  
Control Study

SUMMARY OBJECTIVE: We measured the level of pH gases in premature infants at birth, and examined the relationship between brain ultrasonography on the third and seventh day after birth. A case-control study conducted at the Neonatal Intensive Care Unit (NICU) of Shahid Akbar Abadi Hospital, Iran, during the years 2016-2017. METHODS: All premature infants who were admitted to NICU were enrolled in the current study. At birth, a blood gas sample was taken from the umbilical cord of the infants. On the third and seventh day after birth, an ultrasound of the brain of each neonate was performed by a radiologist. The umbilical cord was evaluated for blood gases in 72 neonates (mostly boys). RESULTS: Sixty-six newborns had normal sonography, and 16.7% (12 cases) had anomalies. A total of 75% of the 8 infants with intravenous bleeding were girls, which were significantly different from those in the non-hemodynamic group (62.5% male) (P 0.049). However, the type of delivery, mean weight, height, head circumference, the circumference of the chest, and Apgar score did not differ between the two groups. Mean pH, HCO3– and PCO2 in umbilical cord blood gas samples were not significantly different between the two groups with or without intraventricular hemorrhage (IVH). Although it was not related to gender and type of delivery in newborns CONCLUSION: Blood gases do not help in determining the occurrence of IVH in infants. Nevertheless, it is associated with immaturity and fetal age.

Amplitude Integrated Electroencephalogram Integration to Monitor the Relationship Between Development and Changes of the Nervous System in Late Preform Infants

2021 ◽  
Vol 11 (6) ◽  
pp. 1704-1712
Author(s):  
Sehua Qu ◽  
Lianqiang Shan ◽  
Xin Chen ◽  
Rui Zhou ◽  
Huaixiang Yin ◽  
...  
Keyword(s):  
Nervous System ◽  
Premature Infants ◽  
Gestational Age ◽  
Exercise Intervention ◽  
Controlled Trial ◽  
Age Groups ◽  
Voltage Difference ◽  
Randomized Controlled ◽  
Neuroprotective Strategy ◽  
The Relationship

This article uses amplitude integration of electroencephalogram integration to detect the development of the nervous system of late perform infants, and to study its changes, using a stratified randomized controlled trial method. The preform infants in the neonatal department of postnatal birth had the research object. The sample size was calculated, according to the first set of tires into small gestational age groups, and gestational age large. The subjects of each group were randomly divided into small gestational age groups, small gestational age intervention groups, large gestational age groups and large gestational age intervention groups. Two preterm children increased with age growth. The performance of the broadband and narrowband sector decreased voltage need the voltage lower bound ofa growing trend to the voltage difference becomes smaller. Oral exercise intervention is safe and effective for premature infants over 30 weeks old and can be used clinically as a neuroprotective strategy.

scholarly journals The Correlation Between Bronchopulmonary Dysplasia and Platelet Metabolism in Preterm Infants

2021 ◽  
Vol 9 ◽  
Author(s):  
Longli Yan ◽  
Zhuxiao Ren ◽  
Jianlan Wang ◽  
Xin Xia ◽  
Liling Yang ◽  
...  
Keyword(s):  
Platelet Count ◽  
Birth Weight ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Gestational Age ◽  
Admission Diagnosis ◽  
Control Group ◽  
The Relationship

Background: Platelets play an important role in the formation of pulmonary blood vessels, and thrombocytopenia is common in patients with pulmonary diseases. However, a few studies have reported on the role of platelets in bronchopulmonary dysplasia.Objective: The objective of the study was to explore the relationship between platelet metabolism and bronchopulmonary dysplasia in premature infants.Methods: A prospective case-control study was performed in a cohort of premature infants (born with a gestational age <32 weeks and a birth weight <1,500 g) from June 1, 2017 to June 1, 2018. Subjects were stratified into two groups according to the diagnostic of bronchopulmonary dysplasia: with bronchopulmonary dysplasia (BPD group) and without bronchopulmonary dysplasia (control group). Platelet count, circulating megakaryocyte count (MK), platelet-activating markers (CD62P and CD63), and thrombopoietin (TPO) were recorded and compared in two groups 28 days after birth; then serial thrombopoietin levels and concomitant platelet counts were measured in infants with BPD.Results: A total of 252 premature infants were included in this study. Forty-eight premature infants developed BPD, 48 premature infants without BPD in the control group who were matched against the study infants for gestational age, birth weight, and admission diagnosis at the age of postnatal day 28. Compared with the controls, infants with BPD had significantly lower peripheral platelet count [BPD vs. controls: 180.3 (24.2) × 109/L vs. 345.6 (28.5) × 109/L, p = 0.001]. Circulating MK count in the BPD group was significantly more abundant than that in the control group [BPD vs. controls: 30.7 (4.5)/ml vs. 13.3 (2.6)/ml, p = 0.025]. The level of CD62p, CD63, and TPO in BPD group was significantly higher than the control group [29.7 (3.1%) vs. 14.5 (2.5%), 15.4 (2.0%) vs. 5.8 (1.7%), 301.4 (25.9) pg/ml vs. 120.4 (14.2) pg/ml, all p < 0.05]. Furthermore, the concentration of TPO was negatively correlated with platelet count in BPD group with thrombocytopenia.Conclusions: Our findings suggest that platelet metabolism is involved in the development of BPD in preterm infants. The possible mechanism might be through increased platelet activation and promoted TPO production by feedback.

In Reply: Pathogenesis of Intraventricular Hemorrhage

PEDIATRICS ◽  
1979 ◽  
Vol 64 (3) ◽  
pp. 387-387
Author(s):  
John D. Kenny ◽  
Joseph A. Garcia-Prats
Keyword(s):  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Elevated Pco2 ◽  
Acid Base ◽  
Rapid Infusion ◽  
Acid Base Status ◽  
The Relationship ◽  
Additional Role

Dr. Wible's comments are interesting and may indeed offer an explanation for the occurrence of IVH in some infants. Since our study pertained to the acid-base status of premature infants at birth this hypothesis does not apply to the infants we studied; nevertheless, it offers an additional role for elevated pCO2 in the etiology of this condition. The relationship between rapid infusion of bicarbonate and IVH has not been adequately established although it has been shown that slow infusions do not increase the risk of IVH.1

scholarly journals Relationship between intraventricular hemorrhage and acute kidney injury in premature infants and its effect on neonatal mortality

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mountasser M. Al-Mouqdad ◽  
Roya Huseynova ◽  
Thanaa M. Khalil ◽  
Yasmeen S. Asfour ◽  
Suzan S. Asfour
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Neonatal Mortality ◽  
Premature Infants ◽  
Intraventricular Hemorrhage ◽  
Neonatal Intensive Care ◽  
Direct Relationship ◽  
Kidney Injury ◽  
Study Population ◽  
The Relationship

AbstractIntraventricular hemorrhage (IVH) and acute kidney injury (AKI) are important neonatal morbidities in premature infants. This study aimed to investigate the relationship between IVH and AKI in premature infants and whether this association affects the incidence of neonatal mortality. Infants [gestational age (GA) ≤ 32 weeks; birth weight (BW) < 1500 g] were retrospectively evaluated in a large tertiary neonatal intensive care unit. Of 710 premature infants, 268 (37.7%) developed AKI. Infants with IVH were more likely to have AKI than those without IVH. Infants with severe IVH had a higher incidence of AKI than infants with mild IVH. Infants younger than 28 weeks with IVH were more likely to have AKI than those without IVH. An association between IVH grades and AKI stages was observed in the overall study population, in infants with GA < 28 weeks, and in infants with GA between 28 and 32 weeks. Mortality was increased 1.5 times in infants with IVH and AKI compared with that in infants with IVH but without AKI. Furthermore, mortality was increased in infants with IVH and AKI compared with infants without IVH or AKI. This study shows a direct relationship between the severity of IVH and the degree of AKI; both IVH and AKI increase the incidence of neonatal mortality.

scholarly journals Baroreflex Sensitivity in Premature Infants – Relation to the Parameters Characterizing Intrauterine and Postnatal Condition

2017 ◽  
pp. S257-S264 ◽  
Author(s):  
K. HASKOVA ◽  
M. JAVORKA ◽  
B. CZIPPELOVA ◽  
M. ZIBOLEN ◽  
K. JAVORKA
Keyword(s):  
Birth Weight ◽  
Premature Infants ◽  
Gestational Age ◽  
Baroreflex Sensitivity ◽  
Close Correlation ◽  
Intrauterine Development ◽  
Premature Newborns ◽  
Actual Weight ◽  
Multifactor Analysis ◽  
The Relationship

At present, there are insufficient information about baroreflex sensitivity (BRS) and factors that determine BRS in premature newborns. The objective of this study was to determine the relationship between BRS and the characteristics that reflecting the intrauterine development (gestational age and birth weight), as well as postnatal development (postconception age and the actual weight of the child at the time of measurement). We examined 57 premature infants, who were divided into groups according to gestational age and postconception age as well as birth weight, and weight at the time of measurement. Continuous and noninvasive registration of peripheral blood pressure (BP) was performed in every child within 2-5 min under standard conditions using a Portapres (FMS) device. The results showed a close correlation of baroreflex sensitivity, heart rate and respiratory rate with gestational age, postconception age, birth weight and actual weight at the time of measurement premature newborns. An increase in the characteristics (ages and weights) resulted in increased BRS and diastolic arterial pressure (DAP), and in decreased heart and respiratory rates. Baroreflex sensitivity in the first week was in the group of very premature newborns the lowest (4.11 ms/mmHg) and in the light premature newborns was almost double (8.12 ms/mmHg). BRS increases gradually in relation to postnatal (chronological) and to postconception age as well as to birth and actual weight. The multifactor analysis of BRS identified birth weight and postconception age as the best BRS predictors. The two independent variables together explained 40 % of interindividual BRS variability.

scholarly journals The relationship between thrombocytopenia and intraventricular hemorrhage in neonates with gestational age <35 weeks

2016 ◽  
Vol 56 (4) ◽  
pp. 242 ◽  
Author(s):  
Idha Yulandari ◽  
Lily Rundjan ◽  
Muzal Kadim ◽  
Pustika Amalia ◽  
Haryanti F. Wulandari ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Gestational Age ◽  
Medical Records ◽  
Intraventricular Hemorrhage ◽  
Health Department ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
High Incidence ◽  
The Relationship ◽  
High Frequency Oscillatory

Background The prevalence of thrombocytopenia in neonates ranges from 22 to 35%, and one of the most feared complica­tions is intraventricular hemorrhage (IVH). Previous research in Cipto Mangunkusumo Hospital (CMH), Jakarta reported a high incidence of IVH (43.47%) in infants with a gestational age of <35 weeks. Intraventricular hemorrhage causes disturbances in neurological development and can be fatal. In Indonesia, re­search on the relationship between thrombocytopenia and IVH has been limited.Objective To study the relationship between thrombocytopenia and IVH in neonates with gestational age <35 weeks and assess for a correlation between the severity of thrombocytopenia and the severity of IVH.Methods This cross-sectional study was performed by reviewing medical records in the Neonatology Division of the Child Health Department, University of Indonesia, CMH. Subjects were neonates hospitalized from January 2012 to December 2014 with IVH. Subjects were categorized into either mild to moderate IVH (grade ≤2) or severe IVH (grade >2). Thrombocyte counts were recorded on the same day as the diagnosis of IVH.Results The risk of severe IVH was 28.2% in neonates with thrombocyte counts <100,000/uL, and 10.4% in neonates without thrombocytopenia (P=0.014). Multivariate analysis revealed that gestational age <32 weeks and the use of respira­tory support (ventilator and high frequency oscillatory ventila­tion) had significant associations with severe IVH. However, multivariate analysis did not show a significant relationship between thrombocytopenia and severe IVH (correlation coef­ficient = 0.21).Conclusion Thrombocytopenia is not significantly associated with the incidence of severe IVH based on multivariate analysis. Also, the severity of thrombocytopenia has no correlation with the severity of IVH.

scholarly journals Statistical Analysis of Blood Cell Parameters in Premature Infants

2015 ◽  
Vol 4 (1) ◽  
pp. 17
Author(s):  
Julan Yu
Keyword(s):  
Birth Weight ◽  
Blood Cell ◽  
Intracranial Hemorrhage ◽  
Premature Infants ◽  
Gestational Age ◽  
Blood Cells ◽  
Cell Parameters ◽  
Clinical Statistics ◽  
The Difference ◽  
The Relationship

<p><strong>Objective: </strong>Analysis and discussion of the clinical statistics of the blood cell parameters in premature infants. <strong>Method: </strong>From May 2008 to January 2015, 85 cases of premature infants were selected to analyze the relationship between blood cell parameters and birth weight, gestational age and the changes of blood cell parameters in premature infants with intracranial hemorrhage. <strong>Results: </strong>Blood cell parameters PDW and PLT were decreased with the decrease of birth weight and gestational age. MPV increased with the decrease of birth weight and gestational age, the difference was statistically significant (<em>p </em>&lt; 0.05). Compared with the non-bleeding group, the intracranial hemorrhage in premature infants with PLT was significantly decreased, the difference was statistically significant <em>(p </em>&lt; 0.05), MPV and PDW were not statistically significant (<em>p </em>&gt; 0.05). <strong>Conclusion: </strong>The blood cell parameters were correlated with the birth weight and gestational age, and the parameters of blood cells were closely related to the complications of premature infants and premature infants with intracranial hemorrhage.</p>

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