Dynamics of indicators of hemostatic system as prognostic criteria consequences of ART programs

2016 ◽  
pp. 165-170
Author(s):  
S. Zhuk ◽  
◽  
V. Vorobey-Vykhivska ◽  

The article deals with the insurense of haemostatic system on the ART result. The objective: of the study was to establish the relationships between the state of hemostasis in dynamics during the ART program and its results. Patients and methods. The study involved 130 women who underwent infertility treatment through IVF. The dynamics of hemostasis indicators for ART programs is investigated. Results. The trend to a hypercoagulable state in women with failed attempts of IVF is fined. Risk factors ART failure due to hemostasis disorders is established. Conclusions. The evolution of the hemostatic system is an important prognostic criteria on the outcome of ART programs. The lack of signs of a hypercoagulable state can be considered a prerequisite for pregnancy. Dynamic monitoring of hemostasis within ART programs will take timely measures on correction of the hemostatic system and to some extent influence the effects of treatment. Key words: infertility, hemostasis, assisted reproductive technology.

GYNECOLOGY ◽  
2019 ◽  
Vol 21 (2) ◽  
pp. 76-79
Author(s):  
Anastasia G Syrkasheva ◽  
Yana A Petrosyan ◽  
Natalia V Dolgushina

Background. Luteal phase (LP) drug support is an important step in assisted reproductive technology (ART) programs efficacy. Aim. To present up-to-date data on an efficacy of LP hormonal support during ART cycles as well as to conduct a comparative analysis of various gestagen drug effectiveness. Materials and methods. To write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 8 years. The review includs articles from peer-reviewed literature. Results. LP drug support becomes an essential step in infertility treatment in various ART programs. Although human chorionic gonadotropin drug injections in the posttransfer period leads to an activation of endogenous steroid hormones synthesis, exogenous hormones use is currently preferred because of not having a risk of ovarian hyperstimulation syndrome. Conclusions. The variety of progesterone drugs is accompanied by a lack of algorithms for their use in various clinical situations. Further studies are required to evaluate progesterone drugs efficacy for various subgroups of patients.


GYNECOLOGY ◽  
2020 ◽  
Vol 22 (6) ◽  
pp. 44-49
Author(s):  
Irena F. Kozachenko ◽  
Veronika Y. Smolnikova ◽  
Leila V. Adamyan

Aim. To evaluate the results of treatment of patients with uterine fibroids and infertility with ineffective art programs in the anamnesis and to identify possible risk factors for repeated art failures. Materials and methods. 510 patients with uterine fibroids and infertility were examined and surgically treated prior to the ART program. Myomectomy was performed using various approaches: laparoscopic access in 250 patients, laparotomic access in 70 patients, hysteroscopic myomectomy in 100 patients, and combined access (laparoscopic and hysteroscopic) in 90 women. Results. Primary infertility was observed in 38.0%, secondary in 62.0% of patients. The average duration of infertility was 4.41.9 years. ART had in history 54.5% of patients. During the follow-up period up to 2 years, 24.3% of women had recurrent uterine fibroids. After carrying out of surgical treatment and the following ART pregnancy was achieved in 44.3% of patients. Pregnancies ended in childbirth in 58.8% of cases, which exceeded the total share (41.6%) of adverse pregnancy outcomes (ectopic pregnancy, abortions, spontaneous miscarriages at various times) by 1.4 times. Conclusion. Risk factors for repeated ART failures in patients who have undergone myomectomy are: age over 40 years; duration of infertility for more than 5 years and the presence of 3 or more ineffective IVF attempts in the history; the presence of previous surgical interventions such as uterine artery embolization and FUS-ablation; the presence of submucous fibroids, a dominant node located close to the uterine cavity and myoma with signs of blood supply disorders; the combination of uterine fibroids with external genital endometriosis and chronic endometritis.


2020 ◽  
pp. oemed-2020-106745
Author(s):  
Yuya Imai ◽  
Motoki Endo ◽  
Keiji Kuroda ◽  
Kiyohide Tomooka ◽  
Yuko Ikemoto ◽  
...  

ObjectiveTo elucidate the risk factors associated with resignation from work of Japanese women undergoing infertility treatment.MethodsA total of 1727 female patients who attended a private fertility clinic in Japan participated in the Japan-Female Employment and Mental health in Assisted reproductive technology study. Questions related to demographic, clinical and socioeconomic characteristics were employed in the questionnaire. Out of the 1727 patients, 1075 patients who were working at the time of initiating infertility treatment and felt infertility treatment incompatible with work were included in the analysis. Risk factors for resignation were assessed by using multivariable logistic regression models.ResultsAmong 1075 working women who started infertility treatment, 179 (16.7%) subsequently resigned. Multivariable-adjusted ORs for resignation in those with lower educational background and infertility for ≥2 years were 1.58 (95% CI: 1.07 to 2.34) and 1.82 (95% CI: 1.15 to 2.89), respectively. The OR for resignation in non-permanent workers undergoing infertility treatment was 2.65 (95% CI: 1.61 to 4.37). While experiencing harassment in the workplace approached significance, lack of support from the company was significantly associated with resignation after starting infertility treatment, with ORs of 1.71 (95% CI: 0.98 to 2.99) and 1.91 (95% CI: 1.28 to 2.86), respectively.ConclusionOne-sixth of women resigned after starting infertility treatments. It was found that factors related to education, infertility duration and work environment were significantly associated with resignation. Reducing the physical and psychological burden endured by women, for example, by increasing employer-provided support, is vitally important in balancing infertility treatment with maintenance of work life.


GYNECOLOGY ◽  
2020 ◽  
Vol 21 (6) ◽  
pp. 36-40
Author(s):  
Anna G. Burduli ◽  
Natalia A. Kitsilovskaya ◽  
Yuliya V. Sukhova ◽  
Irina A. Vedikhina ◽  
Tatiana Y. Ivanets ◽  
...  

The review presents data on metabolites in the follicular fluid (FF) from the perspective of reproductive medicine and their use in order to predict outcomes of assisted reproductive technology (ART) programs. It considers various components of this biological medium (hormones, lipids, melatonin, etc.) with an assessment of their predictive value in prognosis of the effectiveness of in vitro fertilization (IVF) programs. The data on experimental directions in this field and the prospects for their use in clinical practice are presented. The article emphasizes that the growing clinical need and the unsolved problem of increasing the effectiveness of ART programs determine the need for further studies of the FF composition. Materials and methods. The review includes data related to this topic from foreign and Russian articles found in PubMed which were published in recent years. Results. Given the established fact of a direct effect of FF composition on growth and maturation of oocytes, and further, on the fertilization process, various FF metabolites are actively investigated as non-invasive markers of quality of oocytes/embryos. The article provides data on the experimental directions in this field and the prospects for their use in clinical practice. However, clinical studies of a relation between various FF metabolites levels and outcomes of IVF programs are contradictory. Conclusion. Owing large economic cost for treatment of infertility with IVF, there is need for expansion and intensification of studies to identify and use reliable predictors in prognosis of ART programs outcomes.


2021 ◽  
Vol 7 (2) ◽  
pp. 138-170
Author(s):  
Chengpu Yu ◽  
Wanlin Li ◽  
Mingfen Deng

Assisted reproductive technology (ART) is hailed as “the holy grail” for infertile patients in the mainstream narrative. The existing studies have clearly demonstrated how external social factors shape how ART is to be used, but they ignore the recipients of the technologies, and especially the experiences of women. Based on an investigation conducted in Z hospital’s reproductive center, this article regards embodiment as the methodological orientation for integrating socio-cultural context with female embodied experience in order to show their bio-social entanglement. As fieldwork evidence indicates, ART in practice is far from simple “hope technology”; instead, it throws women into a paradoxical world in which hope and anxiety coexist. Embodied experience, hope, and anxiety are transmitted through the bodies of women, which reveals the inscription of social-cultural context and technical uncertainty on the female body and, meanwhile, women actively learn strategies by which to cope with the technical uncertainty and moral pressures from local culture (including healing the body, folk religion, etc.), so as to hold onto infertility treatment with hope.


2016 ◽  
pp. 143-148
Author(s):  
Pavlo Kolesnik ◽  
Timea Korol ◽  
Ivanna Shushman ◽  
Aita Prohorova

The article deals with the question of the prevalence of overweight and obesity among the cohort of mental profession. It determines the level of their motivation for lifestyle changes, as well as possibility to enhance their motivation while using of the guar gum Guarem drug (Orion Corporation, Finland). 161 persons where skinned for diet habits, physical activity, the presence of risk factors as well as dislipidemiya. Motivation for lifestyle changes was evaluated. It was found that the prevalence of overweight and obesity in population with predominantly mental and light physical labor, is extremely high at 68% women and 73% men and incidence increased with age. While dynamic monitoring of the patients, who underwent motivational counseling while taking the drug guar gum Guarem, noted strengthening of motivation to comply with the recommendations, compared with patients who received only verbal motivation.


2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Sonja Pavlovic-Veselinovic

Work-related musculoskeletal disorders (WRMSDs) are becoming a major problem in world economy. There is many and various risk factors that contribute to their development. Repetitive work is one of the most important risk factor. In this paper is described the body's response to repetitive strain, existing methods for evaluation/ quantification of repetition as risk factor for musculoskeletal disorders. The author proposes a new multidimensional scale for rating the level of risk of repetitive work, which may be useful in the risk assessment of the workplace. Key words: ergonomics, work related musculoskeletal disorders, risk assessment.


10.3823/2459 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Ana Dulce Amorim Santos Soares ◽  
Silvana Santiago da Rocha ◽  
Augusto Cezar Antunes de Araujo Filho ◽  
Rosana Dos Santos Costa ◽  
Márcia Teles de Oliveira Gouveia ◽  
...  

The objective was to analyze the scientific collection on nursing care with the skin of hospitalized newborns. In order to reach the objective, an integrative review was conducted. The search for primary studies was performed in the databases LILACS, MEDLINE, BDENF and PUBMED. The included studies (n=10) were grouped into thematic categories: risk factors for skin lesions in hospitalized newborns and their consequences; and nursing care to promote the integrity of the skin of hospitalized newborns. The main care identified were lubrication with emollient agents, use of hydrocolloids and transparent film, changes in decubitus, hygiene techniques, phototherapy and invasive procedures. The results of the review offer guidance for the conduction of researches that investigate interventions that are more effective in the prevention and treatment of skin injuries and their consequences. Key words: Nursing Care, Newborn, Skin.


Author(s):  
Elzbieta T. Kazmierczak

This chapter is a case study, written from the perspective of a visual artist, designer, and educator, reflecting on a five-year volunteer initiative of developing, leading, and funding an art program at a domestic violence shelter for battered women and adolescent girls who experienced sexual violence. One purpose of this chapter is to provide information about establishing art programs that can be sustained by the institutions in which they are introduced. This chapter discusses the following aspects: 1) breaking the ice and establishing rapport; 2) training and supervising staff and student volunteers; 3) fund-raising, grant writing, and seeking support both within and outside the agency; 4) partnering with organizations or community groups to set up art exhibitions; 5) partnering with artists and writers to print and distribute an educational publication; and 6) developing research with vulnerable populations serviced by the agency.


2009 ◽  
Vol 3 ◽  
pp. 9-15 ◽  
Author(s):  
Don Messerschmidt

‘Risk' is a major point of focus in the literature on resettlement and reconstruction associated with the impacts of major infrastructure development on project affected individuals and families. Previous approaches to risk appear to emphasize the negative consequences of development, and it is no wonder then that project affected people often emphatically resist development and change. This paper proposes that a more pro-active, positive opportunities and benefits approach be taken in dealing with resettlement and reconstruction associated with large scale infrastructure projects. The discussion is focused on the eight ‘risk factors' (or ‘opportunity factors'?) listed in the well known ‘Impoverishment Risk and Reconstruction' (IRR) Model. Three more such factors are added to the list based on field experience in South Asia. The point is that by emphasizing the potential opportunities and benefits, project affected people are more likely to be supportive of projects that may disrupt their lives. Key words: Resettlement, opportunities, risk, IRR model, South Asia, infrastructure development  doi: 10.3126/hn.v3i0.1912 Hydro Nepal: Journal of Water, Energy and Environment Issue No. 3, January, 2008 Page 9-15


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