scholarly journals Lactobacillus reuteri DSM 17938 and vitamin D3 in common clinical problems of infants

2021 ◽  
pp. 68-72
Author(s):  
S.P. Kryvopustov ◽  
Keyword(s):  
Vitamin D ◽  
Vitamin D3 ◽  
Lactobacillus Reuteri ◽  
Respiratory Infections ◽  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Gastrointestinal Disorders ◽  
First Year ◽  
Infant Colic ◽  
Clinical Problems

Purpose — to demonstrate the clinical significance of Lactobacillus reuteri DSM 17938 and vitamin D3 in common clinical problems in infants. Materials and methods. Clinical cases in pediatrics of infancy in children with infant colic (G4), infant regurgitation (G1), functional constipation (G7) are presented. Some international recommendations regarding a preventive dose of vitamin D in the first year of a child' life are considered. Results. The behavior of an infant is often a concern for parents and is a reason for seeking medical help. In particular, it has been shown when acute crying of a child is associated with threatening conditions. The prevalence of functional gastrointestinal disorders and the importance of using the Rome IV criteria in practice are emphasized. Clinical examples of infant colic (G4), infant regurgitation (G1), functional constipation (G7) demonstrated the management of patients with the importance of counseling, showing the evidence base for the use of Lactobacillus reuteri DSM 17938 and vitamin D3. Works on the importance of vitamin D for the prevention of respiratory infections and its dosage are presented. Conclusions. For children in the first year of life with infant colic (G4), infant regurgitation (G1), functional constipation (G7), counseling is important, as well as the use of, in particular, Lactobacillus reuteri DSM 17938. Additional benefits are provided by the combined use of Lactobacillus reuteri DSM 17938 with vitamin D3, which is also discussed for the prevention of respiratory infections. Provided international recommendations for a daily preventive dose of 400 IU of vitamin D for infants. No conflict of interest was declared by the author. Key words: vitamin D, infants, respiratory infections, functional gastrointestinal disorders, Lactobacillus reuteri DSM 17938.

scholarly journals Functional gastrointestinal disorders in children: agreement between Rome III and Rome IV diagnoses

2021 ◽  
Author(s):  
Desiree F. Baaleman ◽  
Carlos A. Velasco-Benítez ◽  
Laura M. Méndez-Guzmán ◽  
Marc A. Benninga ◽  
Miguel Saps
Keyword(s):  
Diagnostic Criteria ◽  
Functional Dyspepsia ◽  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Final Analysis ◽  
Gastrointestinal Disorders ◽  
Rome Iii ◽  
Sample Characteristics ◽  
Irritable Bowel ◽  
Rome Iv

AbstractTo evaluate the agreement between the Rome III and Rome IV criteria in diagnosing pediatric functional gastrointestinal disorders (FGIDs), we conducted a prospective cohort study in a public school in Cali, Colombia. Children and adolescents between 11 and 18 years of age were given the Spanish version of the Questionnaire on Pediatric Functional Gastrointestinal Disorders Rome III version on day 0 and Rome IV version on day 2 (48 h later). The study protocol was completed by 135 children. Thirty-nine (28.9%) children were excluded because of not following the instructions of the questionnaire. The final analysis included data of 96 children (mean 15.2 years old, SD ± 1.7, 54% girls). Less children fulfilled the criteria for an FGID according to Rome IV compared to Rome III (40.6% vs 29.2%, p=0.063) resulting in a minimal agreement between the two criteria in diagnosing an FGID (kappa 0.34, agreement of 70%). The prevalence of functional constipation according to Rome IV was significantly lower compared to Rome III (13.5% vs 31.3%, p<0.001), whereas functional dyspepsia had a higher prevalence according to Rome IV than Rome III (11.5% vs 0%).Conclusion: We found an overall minimal agreement in diagnosing FGIDs according to Rome III and Rome IV criteria. This may be partly explained by the differences in diagnostic criteria. However, limitations with the use of questionnaires to measure prevalence have to be taken into account. What is Known:• The Rome IV criteria replaced the previous Rome III criteria providing updated criteria to diagnose functional gastrointestinal disorders (FGIDs).• Differences found between Rome IV and historic Rome III FGID prevalence may have been affected by changes in prevalence over time or differences in sample characteristics. What is New:• We found a minimal agreement between Rome III and Rome IV FGID diagnosis, especially in the diagnoses of functional constipation, irritable bowel syndrome, and functional dyspepsia.• The minimal agreement may be partly explained by changes in diagnostic criteria, but limitations with the use of questionnaires to measure prevalence have to be taken into account.

scholarly journals Prevalence of functional gastrointestinal disorders in infants and young children in China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ying Huang ◽  
Serene Yaling Tan ◽  
Panam Parikh ◽  
Vanitha Buthmanaban ◽  
Shaman Rajindrajith ◽  
...  
Keyword(s):  
Young Children ◽  
Maternal Education ◽  
Functional Gastrointestinal Disorders ◽  
Gastrointestinal Symptoms ◽  
Functional Constipation ◽  
Gastrointestinal Disorders ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
Rome Iv ◽  
Infants And Young Children

Abstract Background The prevalence of functional gastrointestinal disorders (FGIDs) in children, particularly from Asia, is largely unknown. There are not many studies done in Asia especially using the Rome IV criteria. The aim of this study is to assess the prevalence of FGIDs in infants and young children in a representative sample in China. Methods A prospective, cross-sectional, community-based survey was conducted among healthy infants and young children between the ages of 0–4 years in Jinhua and Shanghai, China. A total of 2604 subjects (1300 subjects from Jinhua and 1304 subjects from Shanghai) completed a validated questionnaire on pediatric gastrointestinal symptoms. FGIDs in infants and young children were diagnosed using the Rome IV criteria. Results According to the Rome IV criteria, the prevalence of having a FGID in Chinese infants and young children is 27.3%. Infant regurgitation (33.9%) was the most common FGID among the 0–6 months old while functional constipation (7.0%) was the most common among the 1–4 years old. Risk factor analysis revealed that prevalence of infantile colic was higher with better maternal education and low birth weight. Prevalence of infantile regurgitation was significantly greater in males, living in a rural area, being exclusively breast fed at least up to 4 months and starting formula feeds within the first month. The risk of functional constipation was lower for infants who were delivered vaginally. Conclusions Infantile regurgitation was the most common FGID in Chinese infants while functional constipation was most prevalent among young Chinese children. Trial registration Netherlands Trial Registry Identifier: NL6973/NTR7161.

VITAMIN D PROVISION FOR CHILDREN AND ADULT POPULATION OF THE AMUR REGION

2016 ◽  
Vol 1 (60) ◽  
pp. 57-61 ◽  
Author(s):  
Романцова ◽  
Elena Romantsova ◽  
Борисенко ◽  
Elena Borisenko ◽  
Бабцева ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Respiratory Infections ◽  
Adult Population ◽  
Amur Region ◽  
Preschool Age ◽  
First Year ◽  
First Year Of Life

The aim of the research is to study the availability of vitamin D among children of different age and pregnant women living in the Amur region. 339 residents of Blagoveshchensk (279 children of different age and 60 adults) were examined. Among them there were 129 toddlers, 90 children of preschool age of 3-6 years old, 60 adolescents of 15-17 years old and 60 adults (pregnant women) of 18-40 years old. In the blood serum the content of the metabolite of vitamin D [25(OH)D] was studied by high performance liquid chromatography. The assessment of risk factors for failure and deficiency of vitamin D was conducted by clinical and anamnestic data. The first results of the study have been presented. They indicate a high frequency of various vitamin D deficiency in the population of the Amur region. Among 339 residents of the Amur region 92 (27.1%) had an adequate availability of vitamin D, 144 (42.4%) had an insufficiency of 25(OH)D; at the same time vitamin D deficiency was identified in 90 (26.5%) with 1/3 of the child population and 1/4 of pregnant women. The level of 25(OH)D within normal limits found in 37.5% of children in the first year of life decreased till 3.6 % by 3 years old, with its deficit increasing from 29.1% to 50%, persisting at this level (45.5 percent) in 3-6 year-old children, declining till 23.3% in adolescents and till 23.3% in pregnant women. The average vitamin D in the studied age periods was the highest in the first year of life (36.14±4.3 ng/ml), and the lowest in 2-3 year-old children (19.31±14.68 ng/ml), with a gradual increase in 3-6 years old (21.77±0.96 ng/ml); in 15-17 years old (23.89±0.66 ng/ml) and in pregnant women it has reached a level of 27.75±0.18 ng/ml, remaining below normal values. Respiratory infections, digestion, bone and joint systems pathologies are the most important risk factors contributing to the low status of 25 (OH) D; their prevention, alongside with the correction of vitamin D deficiency can improve the health of the population of the Amur region.

scholarly journals Functional gastrointestinal disorders in infants and toddlers. Online survey results

2020 ◽  
Vol 4 (5) ◽  
pp. 274-281
Author(s):  
M.I. Dubrovskaya ◽  
◽  
E.I. Gryaznova ◽  
Keyword(s):  
Online Survey ◽  
Functional Gastrointestinal Disorders ◽  
Functional Constipation ◽  
Health Condition ◽  
Cyclic Vomiting Syndrome ◽  
Gastrointestinal Disorders ◽  
Infants And Toddlers ◽  
Survey Results ◽  
Delivery Obstetric ◽  
Rome Iv

Aim: to study the possibilities of online surveys for mothers using a questionnaire on the basis of the Rome IV criteria (2016) as a screening for functional gastrointestinal disorders (FGID) in infants and toddlers. Patients and Methods: an anonymous online survey of 477 mothers was conducted regarding the health condition of their children under the age of 4 years. The survey consisted of 2 question pools. The first pool included general questions regarding the age of the mother at the time of delivery, obstetric and gynecological history, feeding of an infant/toddler at the time of the survey. The second pool included questions regarding FGID in infants and toddlers on three separate topics: functional disorders of the first year of life; diagnosis of cyclic vomiting syndrome; bowel movement disorder. Results: among 130 infants, regurgitation was in 50% of cases (at the age of 6 months — in 75%, at the age of 6 to 12 months — in 35%), baby colic — in 49%. The incidence of functional constipation in children under 6 months was 5.8%, from 6 to 12 months — 7.6%, gradually increasing by 3–4 years to 21.5%. Toilet skills were taught to 15 (12%) children aged 1 year — 1 year 11 months, 58 (59%) — at the age of 2 years — 2 years 11 months, and 119 (98%) — at the age of 3 years — 3 years 11 months. Mothers who were unaware of their child’s physical development and/or defecation problems accounted for 20.1% of those who took part in the survey. Conclusion: online survey results of mothers coincide with modern statistical data on FGID disorder. The survey results generally reflect the anatomical and physiological patterns of the child’s GI development. Online survey on the detection of FGID in infants/toddlers allows to make a preliminary diagnosis, identify existing problems and determine further patient management tactics. KEYWORDS: functional gastrointestinal disorders, infant, toddler, Rome IV criteria, questionnaire for parents, functional constipation, online survey, baby colic, regurgitation, toilet skills. FOR CITATION: Dubrovskaya M.I., Gryaznova E.I. Functional gastrointestinal disorders in infants and toddlers. Online survey results. Russian Medical Inquiry. 2020;4(5):274–281. DOI: 10.32364/2587-6821-2020-4-5-274-281.

scholarly journals DETECTION OF GENETIC DETERMINANTS OF PATHOGENICITY OF STRAINS OF KLEBSIELLA SPP. ISOLATED FROM THE INTESTINAL BIOTOPE OF CHILDREN WITH FUNCTIONAL GASTROINTESTINAL DISORDERS

2018 ◽  
Vol 3 (5) ◽  
pp. 60-65
Author(s):  
E. V. Grigorova ◽  
L. V. Rychkova ◽  
E. I. Ivanova ◽  
U. M. Nemchenko ◽  
M. V. Savelkaeva
Keyword(s):  
Functional Gastrointestinal Disorders ◽  
Gastrointestinal Disorders ◽  
First Year ◽  
Genetic Determinants ◽  
Pathogenic Potential ◽  
Bacteriological Study ◽  
Industry Standard ◽  
Comparison Groups ◽  
First Year Of Life ◽  
Klebsiella Spp

Functional gastrointestinal disorders (FGID) are one of the most common problems in children of the first year of life. The aim of the study was to assess the pathogenic potential of Klebsiella spp. strains, isolated from the colon in children of the first year of life with FGID. Material for the study included 61 coprological samples. The biological material was divided into comparison groups, depending on the type of Klebsiella excreted at a concentration of 105–108 CFU/g: 1st – with vegetation in the colon K. pneumoniae (n = 30); 2nd – with vegetation K. oxytoca (n = 31). Bacteriological study composition of the intestinal contents was carried out according to the Industry standard “Protocol of management of patients. Intestinal dysbiosis” (2003). Identification was carried out according to generally accepted schemes using commercial test systems for biochemical identification of bacteria. Statistical data processing was performed using licensed applications “MS Office Excel 2003 for Windows 7”. The data on the quantitative and qualitative changes in the composition microbiota in the comparison groups were obtained. The results of detection genetic determinants of pathogenicity in the samples of Klebsiella of two species show that among the strains of Klebsiella spp., vegetating in the intestines of children as a component of an allochthonous microbiota, a sufficiently high and virulent potential can be concentrated. Detection of pathogenicity genes in bacteria of the genus Klebsiella will expand and deepen the problem of finding the structures of adaptation of strains of bacteria that cause FGID in children of the first year of life.

scholarly journals Neonatal Antibiotics and Prematurity Are Associated with an Increased Risk of Functional Gastrointestinal Disorders in the First Year of Life

2019 ◽  
Vol 212 ◽  
pp. 44-51 ◽  
Author(s):  
Silvia Salvatore ◽  
Maria Elisabetta Baldassarre ◽  
Antonio Di Mauro ◽  
Nicola Laforgia ◽  
Silvio Tafuri ◽  
...  
Keyword(s):  
Functional Gastrointestinal Disorders ◽  
Gastrointestinal Disorders ◽  
First Year ◽  
Increased Risk ◽  
First Year Of Life

MICROBES INSIDE OUR BODIES: CASUAL COMPANIONS, OR PREREQUISITE FOR OUR SURVIVAL? OR WHY PROBIOTICS ARE NEEDED IN INFANT FORMULAE

2020 ◽  
Vol 99 (6) ◽  
pp. 163-171
Author(s):  
S.E. Ukraintsev ◽  
◽  
E.A. Kornienko ◽  
L.I. Kafarskaya ◽  
M.I. Dubrovskaya ◽  
...  
Keyword(s):  
Literature Review ◽  
Lactobacillus Reuteri ◽  
Functional Gastrointestinal Disorders ◽  
Gastrointestinal Disorders ◽  
Effective Prevention ◽  
Symbiotic Relationships ◽  
Positive Effects ◽  
Infant Formulae ◽  
Prevention And Treatment ◽  
Evolutionary Aspects

This literature review describes evolutionary aspects of the formation of relationships between microorganisms and the human body. The formation of symbiotic relationships, which resulted in the formation of a holobiont, is discussed. Separate chapter of the article is dedicated to describing positive effects of Lactobacillus reuteri DSM 17938 strain for human health, including effective prevention and treatment of functional gastrointestinal disorders in infants.

scholarly journals The Epidemiology of Functional Gastrointestinal Disorders in Mexico: A Population-Based Study

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Aurelio López-Colombo ◽  
Douglas Morgan ◽  
Dalia Bravo-González ◽  
Alvaro Montiel-Jarquín ◽  
Socorro Méndez-Martínez ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Utilization ◽  
Functional Gastrointestinal Disorders ◽  
Depression Scale ◽  
Sampling Strategy ◽  
Functional Constipation ◽  
Population Based ◽  
Care Utilization ◽  
Gastrointestinal Disorders ◽  
Population Based Study

Aims.The frequency of functional gastrointestinal disorders (FGIDs) in the general population of Mexico is unknown.Methods.To determine the prevalence of FGIDs, associated depression, and health care utilization, a population-based sampling strategy was used to select 500 households in the State of Tlaxcala, in central Mexico. Household interviews were conducted by two trained physicians using the Rome II Modular Questionnaire, a health-care and medication used questionnaire and the CES-D depression scale.Results.The most common FGIDs were IBS: 16.0% (95% CI: 12.9–19.5); functional bloating: 10.8% (8.2–13.9); unspecified functional bowel disorder: 10.6% (8.0–13.6); and functional constipation (FC): 7.4% (5.3–10.1). Uninvestigated heartburn was common: 19.6% (16.2–23.4). All FGIDs were equally prevalent among both genders, except for IBS (P=0.001), IBS-C (P<0.001), IBS-A/M (P=0.049), and FC (P=0.039) which were more frequent in women. Subjects with FGIDs reported higher frequencies of medical visits: 34.6 versus 16.8%; use of medications: 40.7 versus 21.6%; (bothP<0.001); and reported depression: 26.7 versus 6.7%, (P<0.001).Conclusion.In this first population-based study of FGIDs in Mexico, heartburn, IBS, functional distension, and FC were common. Only IBS, IBS-C, IBS-A/M, and FC were more frequent in women. Finally, FGIDs in Mexico had an increased burden of health care utilization and depression.

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