scholarly journals Research Regarding the Effect of Vitamin E on Some Hematological Parameters in Toxic Stress Conditions in Rats

2020 ◽  
Vol 77 (1) ◽  
pp. 21
Author(s):  
Ana Maria ZAGRAI (MAIEREAN) ◽  
Aurel DAMIAN ◽  
Marian GHITA ◽  
Gavrilă ZAGRAI ◽  
Iulian DUMITRESCU ◽  
...  
Keyword(s):  
Vitamin E ◽  
Blood Cell ◽  
Blood Cells ◽  
Protective Factor ◽  
White Blood Cells ◽  
Harmful Effect ◽  
Specific Effect ◽  
Cellular Respiration ◽  
Control Group ◽  
Cell Parameters

Cadmium’s mechanism of toxicity is manifested by its fixation in mitochondria, inhibition of cellular respiration and oxidative phosphorylation. Vitamin E could act as a protective factor against the harmful effect of Cadmium intoxication. The experimental animals were randomly allocated into 3 experimental groups of 6 rats. The collected blood samples were used to determine hematocrit, hemoglobin concentration, blood erythrocyte count and leukocyte count. The following derived red blood cell parameters were calculated in parallel according to the standard methodology. Between groups 1 and 2 there are no significant differences, a sign that vitamin E exerts an effective protective role. We found a significant increase in the white blood cell count and the neutrophil count in group 3 compared to group 1. Between groups 1 and 2 there are no significant differences, a sign that vitamin E has annihilated the cadmium-induced specific effect. In the case of cadmium poisoned rats, we found a decrease in the number of red blood cells, the hematocrit and the hemoglobin level, but also a significant increase in the number of white blood cells. If rats were treated with cadmium and vitamin E, there were not significant differences from the control group.

scholarly journals Effects of dietary Mannan oligosaccharide (MOS) on grown, survival rate, intestinal morphology and blood cell count of the golden trevally fish (Gnathanodon specious)

2019 ◽  
Vol 19 (4A) ◽  
pp. 241-250
Author(s):  
Dang Tran Tu Tram ◽  
Nguyen Thi Nguyet Hue ◽  
Ho Son Lam ◽  
Nguyen Truong Tan Tai ◽  
Dao Thi Hong Ngoc
Keyword(s):  
Survival Rate ◽  
Blood Cell ◽  
Blood Cells ◽  
White Blood Cells ◽  
Intestinal Morphology ◽  
The Other ◽  
Control Group ◽  
Blood Cell Count ◽  
Mannan Oligosaccharide ◽  
Erythrocyte Density

The golden trevally fishes (Gnathanodon specious) (2.19 ± 0.23 g) were cultured in glass tanks with density of 20 fishes/tank and they were fed supplemental diets of different MOS concentrations (0; 0.2; 0.4 and 0.6%) for 90 days. Collected data included growth rate, survival rate and some hematological characteristics of this fish. The results demonstrated that MOS supplementation did not affect growth performance, erythrocyte density and blood cell size, however the survival rate was significantly increased. On the other hand, the total number of white blood cells (BC) on the 60th day in the fish fed with MOS supplements (5.78–6.96 × 104TB/mm3) was higher than that in the control group (only 5.43 × 104TB/mm3) with the largest total leukocytes (6.96 ± 0.50 × 104TB /mm3) at 0.2% MOS (p < 0.05).

scholarly journals Changes in white blood cells in sheep blood during selenium supplementation

2008 ◽  
Vol 53 (No. 5) ◽  
pp. 255-259 ◽  
Author(s):  
L. Pisek ◽  
J. Travnicek ◽  
J. Salat ◽  
V. Kroupova ◽  
M. Soch
Keyword(s):  
Blood Cell ◽  
White Blood Cell ◽  
Blood Cells ◽  
White Blood Cells ◽  
Microscopic Analysis ◽  
Blood Parameters ◽  
Selenium Supplementation ◽  
Cell Parameters ◽  
Organic Selenium ◽  
The Impact

The aim of the experiment was to evaluate the impact of selenium supplementation on white blood cell parameters in the blood of ewes. The total white blood cell (WBC) and differentiation of leukocytes in blood smear were detected by a microscopic analysis, and the CD4<sup>+</sup> and CD8<sup>+</sup> subsets were detected by flow cytometry. A decrease in the count of WBC was recorded during pregnancy; it was statistically significant only in the group supplemented with organic selenium. In the postpartal period there was a statistically significant increase in the percentages of CD4<sup>+</sup> and CD8<sup>+</sup> subsets but differences between the groups were not statistically significant. The results of the experiment documented that the supplementation of different forms of selenium did not markedly influence the dynamics of blood parameters in non-pregnant, pregnant and lactating ewes if the intake of vitamins and other essential microelements was adequate.

scholarly journals Effect of Fluticasone and Salmeterol on Tracheal Responsiveness to Ovalbumin and Lung Inflammation, Administrated during and after Sensitization

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Zahra Gholamnezhad ◽  
Mohammad Hossain Boskabady ◽  
Mohammad Reza Khazdair ◽  
Mahmoud Hosseini ◽  
Mahdi Abbasnejad
Keyword(s):  
Fluticasone Propionate ◽  
Blood Cell ◽  
White Blood Cell ◽  
Blood Cells ◽  
Lung Inflammation ◽  
White Blood Cells ◽  
Control Group ◽  
Treatment Groups ◽  
Group B ◽  
Differential White Blood Cell

The effect of duration of administration of fluticasone propionate and salmeterol on tracheal responsiveness to ovalbumin and total and differential white blood cell in sensitized guinea pig was examined. Six groups of guinea pigs (n=7) were sensitized to ovalbumin. Three groups of them were subjected to inhaled fluticasone propionate and salmeterol, one group during sensitization (A), one group after that (for 18 days, B), and the other one during sensitization but with 18 days delay before measurements (C). Three other groups were treated with placebo in the same manner. The tracheal responsiveness to ovalbumin and total and differential white blood cells of three placebo groups were significantly higher than those of control group (P<0.001for all cases). Tracheal responsiveness to ovalbumin and total and differential white blood cell in treated groups with fluticasone propionate and salmeterol were significantly decreased compared to those of placebo groups (nonsignificant toP<0.001). The improvement in all variables in treatment groups A and C were more pronounced than group B. The results showed that fluticasone propionate and salmeterol had a prevention effect on tracheal hyperresponsiveness to ovalbumin and lung inflammation which was more pronounced when administered during than after sensitization.

scholarly journals Continuous changes in biological levels of complete blood count in a high altitude area of China

2020 ◽  
Vol 8 ◽  
pp. 205031212093133 ◽  
Author(s):  
Xuan Luo ◽  
Lei Feng ◽  
XueJing Bai ◽  
JiangXian Zhu ◽  
GuanCheng Zhao ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Complete Blood Count ◽  
White Blood Cells ◽  
Age Groups ◽  
Reference Interval ◽  
Distribution Width ◽  
Men And Women ◽  
Cell Parameters

Objectives: We aimed to establish a new reference interval of blood cell parameters by classifying and counting blood Cells of 16- to 85-year-old healthy volunteers and observing continuous changes with age. Methods: We analyzed the blood cell parameters of 42,678 cases (men, 24,406; women, 18,272), and compared the blood cell parameters of men and women in different age groups using an independent samples t-test. Using limits of 2.5%–97.5%, a 90% confidence interval was used to develop new reference intervals. Results: Counts of blood cell parameters, including white blood Cells, neutrophils, lymphocytes, monocytes, eosinophils, basophils, red blood Cells, hemoglobin, hematocrit, distribution width of red blood Cells and platelets, were found to differ between men and women in different age groups. These parameters were used to establish a new reference interval of blood Cells. Conclusion: The blood cell parameters of both men and women changed with increasing age. The reference interval that we established will provide more accurate basic evidence for clinical diagnosis and treatment of diseases.

Changes of Blood Leukocyte and Blood Glucose in Patients with Acute Craniocerebral Trauma and Nursing Effect

2021 ◽  
Vol 7 (5) ◽  
pp. 1670-1680
Author(s):  
Junyi Yang
Keyword(s):  
Blood Glucose ◽  
Brain Injury ◽  
Blood Cell ◽  
White Blood Cell ◽  
Blood Cells ◽  
White Blood Cells ◽  
Craniocerebral Trauma ◽  
Control Group ◽  
Craniocerebral Injury ◽  
Significant Difference

Acute craniocerebral injury is one of the most common injury types, and its mortality rate ranks first among all kinds of injuries. The changes of white blood cells and blood glucose play an important role in the treatment and nursing of patients. The purpose of this study is to analyze the changes of white blood cells and blood glucose in patients with acute craniocerebral trauma and nursing effect. In this study, 65 patients with craniocerebral injury admitted to the Department of Neurosurgery of our hospital from January 2017 to September 2019 were selected as the research objects. After admission, appropriate nutritional treatment was given according to the condition of patients. Blood samples were collected on fasting in the morning of 2, 8 and 15 days after admission, while those in the control group were collected by fasting vein for detection of white blood cells, blood glucose, blood lipid, blood uric acid and other indicators. There was no significant difference in the number of neutrophils in each group (P < 0.05, P < 0.05, P < 0.05, P < 0.05, P < 0.05). After acute traumatic brain injury, the white blood cells and blood glucose of patients increased, and the more severe the degree of brain injury, the higher the white blood cell count and blood glucose. This study will contribute to the analysis of white blood cell and blood glucose changes and nursing care of patients with craniocerebral injury.

scholarly journals Preparation and Evaluation of a 7-Parameter Intralaboratory Control Blood of 4-Month Stability

1983 ◽  
Vol 20 (5) ◽  
pp. 302-307 ◽  
Author(s):  
A J P F Lombarts ◽  
B Leijnse
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Blood Cells ◽  
White Blood Cells ◽  
Established Method ◽  
Cell Parameters ◽  
Long Term Stability ◽  
Human Red Blood Cells ◽  
Preparation And Evaluation

Sterile, fresh concentrates of human red blood cells suspended in a specially designed sterile preservation medium have a stability of all six red blood cell parameters of over four months as measured in the Coulter Model S-Plus II. Substitution under sterile conditions of the unstable white blood cells for (commercially available) fixed (human) red blood cells is a well-established method to obtain simulated white blood cell suspensions of long-term stability.

Blood Cell Parameters and Predicting Coronary In-Stent Restenosis

Angiology ◽  
2019 ◽  
Vol 70 (8) ◽  
pp. 711-718 ◽  
Author(s):  
Zhichao Wang ◽  
Chi Liu ◽  
Hong Fang
Keyword(s):  
Blood Cell ◽  
Platelet Activation ◽  
Blood Cells ◽  
Inflammatory Marker ◽  
Distribution Width ◽  
Cell Parameters ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Stent Restenosis ◽  
In Stent Restenosis

Major advances in coronary interventional techniques and pharmacotherapy as well as the use of drug-eluting stents (DESs) have considerably reduced the risk of in-stent restenosis (ISR). However, ISR remains a major clinical challenge. Inflammation and platelet activation are important processes that underlie the pathophysiology of ISR. Parameters related to blood cells, entailing both cell count and morphology, are useful markers of the inflammatory response and platelet activation in clinical practice. Recent studies have highlighted several new combined or derived parameters related to blood cells that independently predict ISR after DES implantation. The neutrophil/lymphocyte ratio, an inflammatory marker, is regarded as a predictor of the risk of ISR and the stability of atherosclerotic plaques. The mean platelet volume, a widely used platelet activation parameter, has been shown to be a predictor of the risk of ISR and the efficacy of antiplatelet therapy. Other markers considered include the platelet/lymphocyte ratio, red blood cell distribution width, and platelet distribution width. This review provides an overview of these parameters that may help stratify the risk of coronary angiographic and clinical outcomes related to ISR.

scholarly journals White Blood Cells and Severe COVID-19: A Mendelian Randomization Study

2021 ◽  
Vol 11 (3) ◽  
pp. 195
Author(s):  
Yitang Sun ◽  
Jingqi Zhou ◽  
Kaixiong Ye
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Blood Cells ◽  
Mendelian Randomization ◽  
Association Studies ◽  
White Blood Cells ◽  
Genome Wide Association Studies ◽  
Blood Cell Count

Increasing evidence shows that white blood cells are associated with the risk of coronavirus disease 2019 (COVID-19), but the direction and causality of this association are not clear. To evaluate the causal associations between various white blood cell traits and the COVID-19 susceptibility and severity, we conducted two-sample bidirectional Mendelian Randomization (MR) analyses with summary statistics from the largest and most recent genome-wide association studies. Our MR results indicated causal protective effects of higher basophil count, basophil percentage of white blood cells, and myeloid white blood cell count on severe COVID-19, with odds ratios (OR) per standard deviation increment of 0.75 (95% CI: 0.60–0.95), 0.70 (95% CI: 0.54–0.92), and 0.85 (95% CI: 0.73–0.98), respectively. Neither COVID-19 severity nor susceptibility was associated with white blood cell traits in our reverse MR results. Genetically predicted high basophil count, basophil percentage of white blood cells, and myeloid white blood cell count are associated with a lower risk of developing severe COVID-19. Individuals with a lower genetic capacity for basophils are likely at risk, while enhancing the production of basophils may be an effective therapeutic strategy.

scholarly journals Blood Cell Count Using Deep Learning Semantic Segmentation

2019 ◽  
Author(s):  
Thanh Tran ◽  
Lam Binh Minh ◽  
Suk-Hwan Lee ◽  
Ki-Ryong Kwon
Keyword(s):  
Deep Learning ◽  
Blood Cell ◽  
Cell Count ◽  
Blood Cells ◽  
Blood Smear ◽  
White Blood Cells ◽  
Semantic Segmentation ◽  
Peripheral Blood Smear ◽  
Cell Counting ◽  
Blood Cell Count

Clinically, knowing the number of red blood cells (RBCs) and white blood cells (WBCs) helps doctors to make the better decision on accurate diagnosis of numerous diseases. The manual cell counting is a very time-consuming and expensive process, and it depends on the experience of specialists. Therefore, a completely automatic method supporting cell counting is a viable solution for clinical laboratories. This paper proposes a novel blood cell counting procedure to address this challenge. The proposed method adopts SegNet - a deep learning semantic segmentation to simultaneously segment RBCs and WBCs. The global accuracy of the segmentation of WBCs, RBCs, and the background of peripheral blood smear images obtains 89% when segment WBCs and RBCs from the background of blood smear images. Moreover, an effective solution to separate grouped or overlapping cells and cell count is presented using Euclidean distance transform, local maxima, and connected component labeling. The counting result of the proposed procedure achieves an accuracy of 93.3% for red blood cell count using dataset 1 and 97.38% for white blood cell count using dataset 2.

scholarly journals PO-283 Correlation Analysis between Blood Cell Viability, Five Elements and Competition Performance of Elite Men’s Rowers

2018 ◽  
Vol 1 (5) ◽  
Author(s):  
Junbei Bai
Keyword(s):  
Blood Cell ◽  
Red Blood Cells ◽  
Aerobic Capacity ◽  
Red Blood Cell ◽  
Iron Content ◽  
Blood Cells ◽  
White Blood Cells ◽  
Cell Activity ◽  
Ordinary People ◽  
Five Elements

Objective To observe the national elite male rowers blood, red blood cell activity and serum copper, zinc, calcium, magnesium and iron content of the five elements, and compared with the ordinary people. Aimed to investigate the between athletes, athletes and ordinary differences between the two sets of indicators and to explore the impact of element contents in red blood cell activity and five factors. Trying to bring two sets of indicators and specific combining ability, used in training on the monitoring function, and for the future to provide some references for further study. Methods It was included 22 athletes and 22 ordinary men, as the research object, in the collection of blood, measuring red blood cell activity in the blood content of the five elements, simultaneous measurement of physical indicators , will be doing all the data at the differences between the two groups compared to the group to do correlation analysis. The recent record of 2000m, 6000m rowing Dynamometer test results, and red blood cell activity associated with the five elements of content analysis. Results 1. Athletes indicators related to aerobic exercise were significantly higher than ordinary people. The white blood cells of athletes group were average.It shows that athletes have high aerobic capacity, while white blood cells are more stable than normal people. The members of the national rowing men's iron, magnesium content was significantly higher than ordinary group, the iron content is higher than the normal reference value; blood calcium levels were significantly lower than ordinary people, and lower than the normal reference value. The total number of red blood cells and the number of living cells was very significant positive correlation in two groups subjects; Red blood cell activity and red blood cell diameter is proportional, and red blood cell roundness in inverse proportion to the relationship; from this experiment a special ability to see red blood cell activity and there is no correlation. In both groups, hemoglobin was positively correlated with iron content, while iron was positively correlated with copper content. Conclusions 1. Increasing the number and volume of red blood cells can effectively increase the activity of red blood cells; red blood cell activity has no correlation with specific ability, and can not be used as an indicator to determine specific ability. The content of iron and magnesium in rowers is higher than that in ordinary people, which indicates that the adjustment of aerobic capacity and nerve control is very effective. The lower calcium content indicates that the injury caused by calcium loss should be prevented and the urgency of calcium supplementation should be emphasized. In training, we should pay attention to increasing hemoglobin content and aerobic capacity by supplementing iron. We can further consider the effect of supplementing copper to promote iron supplementation.

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