scholarly journals Tyrosinase Inhibitory and Antioxidant Activity of Wild Prunus spinosa L. Fruit Extracts as Natural Source of Bioactive Compounds

2019 ◽  
Vol 47 (3) ◽  
Author(s):  
Milica I. STANKOVIĆ ◽  
Vesna Lj. SAVIĆ ◽  
Jelena V. ŽIVKOVIĆ ◽  
Vanja M. TADIĆ ◽  
Ivana A. ARSIĆ
Keyword(s):  
Antioxidant Activity ◽  
Propylene Glycol ◽  
Bioactive Compounds ◽  
Pharmaceutical Formulations ◽  
Extraction Yield ◽  
Digital Object Identifier ◽  
Fruit Extracts ◽  
Prunus Spinosa ◽  
Methanolic Extracts ◽  
Wild Fruits

In recent years, naturally derived tyrosinase inhibitors and antioxidants have become very important, since the synthetic ones are related with several side effects. As wild fruits are rich source of bioactive compounds, this study focused on the examination of Prunus spinosa L. (blackthorn) fruit extracts, widely distributed in our country. However, blackthorn extracts are not enough investigated, and there are only a few published works. Extraction efficiency of P. spinosa ultrasonic fruit extracts obtained by using different solvents (methanol, 70% (v/v) ethanol, 45% (w/w) propylene glycol and water) was evaluated, regarding polyphenolic profile, tyrosinase inhibitory and antioxidant activity. Results suggested that extracts with 45% propylene glycol and water were particularly rich in polyphenolic compounds (especially phenols, flavonoids and anthocyanins). The highest extraction yield was for 45% propylene glycol extract. This extract showed higher tyrosinase inhibitory and antioxidant activity compared to others, while the methanolic extracts had the highest chelating capacity. Therefore, P. spinosa fruit extracts, especially extracts obtained by ultrasonic extraction with 45% propylene glycol, have a great potential to be incorporated in some pharmaceutical formulations for obtaining tyrosinase inhibitory and antioxidant effects.   ********* In press - Online First. Article has been peer reviewed, accepted for publication and published online without pagination. It will receive pagination when the issue will be ready for publishing as a complete number (Volume 47, Issue 3, 2019). The article is searchable and citable by Digital Object Identifier (DOI). DOI link will become active after the article will be included in the complete issue. *********

scholarly journals The Effect of Cold Plasma Pretreatment on Water-Suspended Herbs Measured in the Content of Bioactive Compounds, Antioxidant Activity, Volatile Compounds and Microbial Count of Final Extracts

Antioxidants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1740
Author(s):  
Ewelina Pogorzelska-Nowicka ◽  
Monika Maria Hanula ◽  
Marta Brodowska-Trębacz ◽  
Elżbieta Górska-Horczyczak ◽  
Urszula Jankiewicz ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Plasma Treatment ◽  
Volatile Compounds ◽  
Bioactive Compounds ◽  
Cold Plasma ◽  
New Technology ◽  
Echinacea Purpurea ◽  
Extraction Process ◽  
Extraction Yield ◽  
Microbial Count

Cold plasma is a new technology of promising potential to use as a part of technological extraction lines constructed to implement green chemistry solutions or simply to reduce resources in solvent-based extraction lines. The present study was undertaken to verify the effect of nitrogen cold plasma pre-treatment conducted for 8 min (20 kHz) on the content of antioxidants, antioxidant activity, the profile of volatile compounds, microbial count, pH and color measured in herb extracts (12 herbs: Echinacea purpurea; Salvia officinalis; Urtica dioica; Polygonum aviculare; Vaccinium myrtillus; Taraxacum officinale; Hypericum perforatum; Achillea millefolium; Sanguisorba officinalis; Leonurus cardiaca; Ballota nigra; Andrographis paniculata) obtained with its usage. The surface morphology of extracted herbs was examined as well. Herbs used for extraction were ground and suspended in water before cold plasma treatment, which is a novel approach not studied before. Most plasma-treated extracts were characterized by a higher content of polyphenols (11 out of 12). Content of flavonoids and anthocyanins increased in four extracts and in the case of anthocyanins was significantly higher in comparison to control (up to 77%). The antioxidant activity measured at least by one method (ABTS, DPPH, FRAP) was also higher in nine plasma-treated solutions. Moreover, plasma decreased total aerobic bacteria, affected the color and increased pH of the extracts. The surface structure of the plant material after the extraction process was significantly damaged, which probably led to a higher extraction yield of bioactive compounds and in consequence to the higher antioxidant activity of extracts obtained with the cold plasma treatment.

Bioactive compounds content and antioxidant activity of Phyllanthus emblica fruit extracts from different varieties cultivated in Thailand

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
W Pothitirat ◽  
S Prakanchinakorn ◽  
P Longpayom ◽  
J Khuankaew ◽  
P Sithisarn ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Phyllanthus Emblica ◽  
Fruit Extracts

scholarly journals Recovery of Bioactive Compounds from Unripe Red Grapes (cv. Sangiovese) through a Green Extraction

Foods ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 566 ◽  
Author(s):  
Giovanna Fia ◽  
Ginevra Bucalossi ◽  
Claudio Gori ◽  
Francesca Borghini ◽  
Bruno Zanoni
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Pantothenic Acid ◽  
Extraction Yield ◽  
Water Soluble ◽  
Industrial Scale ◽  
P Value ◽  
High Concentration ◽  
Total Anthocyanin ◽  
Green Extraction

Unripe grapes are a potential source of bioactive compounds which can exert antioxidant and antimicrobial activity. However, very little information is available about the composition of unripe grapes extracts and their extraction techniques. This study aims to evaluate the recovery of bioactive compounds and the antioxidant activity of the extract from unripe Sangiovese grapes obtained at an industrial-scale and the composition of the extract during processing. The extraction yield was approximately 75%. During the extraction, the total phenol (TP), antioxidant activity (AA) total anthocyanin (TAnt), pantothenic acid and choline content significantly increased. High concentrations of TP (2522 mgCATeq/L), AA (8227 μmolTEAC/L) and total water-soluble vitamins (1397 μg/L) were reached at the end of process. The antioxidant activity of the extract was positively correlated with all the phenol compounds and the highest correlations were found with procyanidin B1 (r = 0.994; p-value < 0.004), procyanidin B2 (r = 0.989; p-value < 0.004), kaempferol 3-O-glucoside (r = 0.995; p-value < 0.004) and quercetin 3-O-hexoside (r = 0.995; p-value < 0.071). Our findings contribute to the knowledge of the bioactive composition of unripe grapes. An efficient industrial-scale “green” extraction method, ready to be transferred to the wine sector, was developed to obtain a safe extract with a high concentration of bioactive compounds.

scholarly journals The Content in Bioactive Compounds of Different Brewers' Spent Grain Aqueous Extracts

2016 ◽  
Vol 73 (2) ◽  
pp. 143 ◽  
Author(s):  
Anca FARCAS ◽  
Sonia SOCACI ◽  
Maria TOFANA ◽  
Elena MUDURA ◽  
Liana SALANTA
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Extraction Time ◽  
Aqueous Extracts ◽  
Food Ingredients ◽  
Extraction Solvent ◽  
Methanolic Extracts ◽  
Water As Solvent ◽  
Food And Beverage ◽  
Spent Grain

In the last decade by-products of food and beverage processing have attracted much attention due to their functionality and potential as food ingredients. Brewers’ spent grain is the major by-product of the brewing industry representing a valuable source of bioactive ingredients. The aim of this study was to assess the effect of extraction time and temperature on the efficiency of water as solvent for the extraction of bioactive compounds from brewers’ spent grain (BSG). In terms of extraction efficiency, the results from polyphenols, flavonoids and antioxidant activity, showed that the best extraction parameters for aqueous extracts are 90⁰C and 60 minutes. In comparison with the control, the best extraction method generated 87% of the phenolics and 43.46% of the flavonoids obtained by a methanol extraction. The preliminary results for the aqueous extracts showed that water can be used as extraction solvent, but a higher extraction time and temperature are needed in order to have a content in bioactive compounds similar to that of methanolic extracts. The obtained values for polyphenols, flavonoids and antioxidant activity, emphasize the importance and the opportunities of the reuse of this agro-industrial waste.

Antioxidant activity of methanolic extracts and some bioactive compounds of Atriplex halimus

2009 ◽  
Vol 12 (12) ◽  
pp. 1259-1266 ◽  
Author(s):  
Nabila Benhammou ◽  
Fawzia Atik Bekkara ◽  
Tatjana Kadifkova Panovska
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Atriplex Halimus ◽  
Methanolic Extracts

scholarly journals Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mohammad Khairul Alam Sobuj ◽  
Md. Ariful Islam ◽  
Md. Shoebul Islam ◽  
Md. Mohidul Islam ◽  
Yahia Mahmud ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Antioxidant Activities ◽  
Brown Seaweed ◽  
Reducing Power ◽  
Total Phenolic ◽  
Gracilaria Tenuistipitata ◽  
Padina Tetrastromatica ◽  
Methanolic Extracts

AbstractSeaweeds are now recognized as a treasure of bioactive compounds. However, the bioactivity of seaweed originating in Bangladesh is still unexplored. So, this study was designed to explore the secondary metabolites and antioxidant activities of solvent extracts of Padina tetrastromatica and Gracilaria tenuistipitata. Phytochemical screening and FTIR spectra confirm the diverse type of bioactive compounds. Antioxidant activity of extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2, 2-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), reducing power (RP), phosphomolybdenum, hydrogen peroxide and nitric oxide (NO) scavenging assays. Here, methanolic extract of P. tetrastromatica showed highest amount of total phenolic content (85.61 mg of GA/g), total flavonoid content (41.77 mg of quercetin/g), DPPH (77.07%), ABTS (77.65%), RP (53.24 mg AAE/g), phosphomolybdenum (31.58 mg AAE/g), hydrogen peroxide (67.89%) and NO (70.64%) assays compared to its methanolic extracts of G. tenuistipitata. This study concluded that methanol as a solvent extract of brown seaweed (P. tetrastromatica) exhibited bioactivity and antioxidant potentiality which will be useful for pharmacological as well as in functional food application.

scholarly journals Phytochemical Composition and Antioxidant Activity of Various Grain Amaranth Cultivars

2019 ◽  
Vol 47 (4) ◽  
pp. 1153-1160 ◽  
Author(s):  
Andreea STĂNILĂ ◽  
Bogdan CIOANCA ◽  
Zorița DIACONEASA ◽  
Sorin STĂNILĂ ◽  
Nicușor SIMA ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Protein Content ◽  
Dry Weight ◽  
Total Protein Content ◽  
Digital Object Identifier ◽  
Total Polyphenols ◽  
Grain Amaranth ◽  
Methanolic Extracts ◽  
Mean Differences ◽  
Red Dye

This study quantified differences in methanolic extracts composition among four grain amaranth cultivars (e.g. ‘Hopy Red Dye’, ‘Amont’, ‘Plenitude’, and ‘Golden Giant’) farmed under three planting conditions: no irrigation/no fertilization (NN), no irrigation/fertilization (NF), irrigation/no fertilization (IN). The study main outcomes were total flavonoids, polyphenols, antioxidant activity, and protein content. Antioxidant activity was assessed using two Single Electron Transfer (SET) based assays: the 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) radical cation decolorization assay (ABTS) and cupric reducing antioxidant capacity (CUPRAC). The total protein content was assessed by Gornall spectrophotometric method, the total flavonoid content (TFC) was determined using a colorimetric technique, while total polyphenols content (TPC) was assessed using the Folin-Ciocalteu method. Mean differences in outcomes were calculated using ANOVA and Dunnet’s test for multiple comparisons. The findings revealed that TPC ranged from 5 to 18 mg gallic acid equivalents (GAE)/100 g dry weight (DW), being highest in ‘Plenitude’ under NF conditions. The highest TFC (7.5 mg quercetin equivalent (QE)/100 g DW) and the highest protein content (37.25%) were revealed for the ‘Hopi Red Dye’ cultivar under the NF planting conditions. Amaranth seeds represent a potential rich source of polyphenols and protein gluten-free compounds, with the ‘Hopi Red Dye’ representing the richest cultivar in such compounds. Fertilized and non-irrigated soil provided the optimal planting conditions across all amaranth cultivars.   ********* In press - Online First. Article has been peer reviewed, accepted for publication and published online without pagination. It will receive pagination when the issue will be ready for publishing as a complete number (Volume 47, Issue 4, 2019). The article is searchable and citable by Digital Object Identifier (DOI). DOI link will become active after the article will be included in the complete issue. *********

scholarly journals Phenolic Profiles and Biological Activities of Extracts from Edible Wild Fruits Ehretia tinifolia and Sideroxylon lanuginosum

Foods ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2710
Author(s):  
Imelda N. Monroy-García ◽  
Irma Edith Carranza-Torres ◽  
Pilar Carranza-Rosales ◽  
María Oyón-Ardoiz ◽  
Ignacio García-Estévez ◽  
...  
Keyword(s):  
Biological Activities ◽  
Radical Scavenging ◽  
Sweet Taste ◽  
Biological Properties ◽  
Fruit Extracts ◽  
Methanolic Extracts ◽  
Wild Fruits ◽  
Wild Fruit ◽  
Phenolic Profiles ◽  
Radical Scavenging Ability

Ehretia tinifolia Linnaeus (Boraginacea) and Sideroxylon lanuginosum Michaux (Sapotaceae) are wild fruits consumed in North America and are appreciated for their pleasant flavor and sweet taste. However, details regarding their composition and biological properties in the available literature are scarce. This study reports the phenolic composition, antioxidant, antiproliferative activities, and digestive enzymatic inhibition of amberlite-retained methanolic extracts from both fruits. Results revealed that these wild fruit extracts are rich in antioxidants. S. lanuginosum had lower phenolic but higher flavonoid contents (21.4 ± 1.5 mg GAE/100 g FW and 6.42 ± 0.9 mg CE/100 g FW) than E. tinifolia (64.7 ± 2.6 mg GAE/100 g FW and 5.1 ± 0.4 mg CE/100 g FW). HPLC-DAD-MS/MS analysis showed rosmarinic acid as a major polyphenol in E. tinifolia and quercetin glucoside in S. lanuginosum. Polyphenols content in E. tinifolia was related to a significant free radical scavenging ability: DPPH (EC50 = 0.32 ± 0.03 mg/mL), TEAC (4134 ± 9.7 μM TE/g dry extract), and hemolysis inhibition (IC50 = 58.55 ± 2.4 μg/mL). Both extracts were capable of inhibiting α-glucosidase, partially inhibiting α-amylase, and showed no inhibition against lipase, while showing antiproliferative activity against HeLa, HT-29 and MCF-7 cancer cell lines. Our study revealed that these wild fruit extracts are rich in health-beneficial phytochemicals and hold significant potential for elaborating functional foods.

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