scholarly journals Effect of Parkia biglobosa seed on lipid profile of dexamethasone-treated pregnant rats

2021 ◽  
Vol 8 (3) ◽  
pp. 030-039
Author(s):  
Funmilola Comfort Oladele ◽  
Bashirat Motunrayo Oluokun ◽  
Omotola Blessing Adam
Keyword(s):  
Lipid Profile ◽  
Plasma Glucose ◽  
Animal Feed ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Open Market ◽  
Parkia Biglobosa ◽  
Pregnant Rats

This study was aimed at evaluating the effect of Parkia biglobosa seed on dexamethasone-treated pregnant rats. Locust bean seeds were purchased from an open market in Ado Ekiti, Nigeria. It was processed and ground into powder which was subsequently used in formulating feed for experimental animals. Fifteen female pregnant rats were divided in three groups of five each. Animals in group A were exposed to standard animal feed only. This served as the control group. Those in group B were exposed to animal feed mixed with locust beans + 0.3 mg/kg body weight of dexamethasone, while those in group C were exposed to animal feed mixed with locust beans. At the end of eight days treatment, animals were sacrificed and blood sample was collected into EDTA bottles and centrifuged. Plasma was separated and used for the determination of glucose and lipid profile. Exposure of animals to dexamethasone was observed to significantly (p<0.05) increased the concentration of plasma glucose concentration when compared with the control as well as animals treated with P. biglobosa only. Animals treated with dexamethasone along with P. biglobosa were observed to have higher concentrations of triglyceride, total cholesterol, low density lipoprotein (LDL) and very low density lipoprotein (VLDL) when compared with those in animals in the control group as well as those treated with P. biglobosa only. Observations from this study revealed that dexamethasone adversely perturbed and unhinged plasma glucose and lipid profile in female pregnant rats while P. biglobosa-formulated diet was observed to be a potent hypoglycemic and hypolipidemic agent.

Effect of Turmeric and Ginger on Lipid Profile in Male Rats Exposed to Oxidative Stress

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Drinking Water ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Male Rats ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.

scholarly journals Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

2017 ◽  
Vol 9 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Chidozie N. OKOYE ◽  
Samuel O. EKERE ◽  
Onyinyechukwu A. AGINA ◽  
Ikechukwu J. UDEANI ◽  
Chukwunonso K. EZEASOR
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Epididymal Sperm ◽  
Treatment Groups ◽  
Egg Consumption ◽  
Group A ◽  
The Mean

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

scholarly journals The effect of different intensities of magnetically treated water on lipid profile of Turkish- Awassi rams

2012 ◽  
Vol 36 (0A) ◽  
pp. 181-186
Author(s):  
Suad A. Jashamy
Keyword(s):  
Lipid Profile ◽  
Blood Sample ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Experimental Period ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
Treated Water ◽  
The Third

A total of 15 Turkish- Awassi rams at ages ranged 2 - 2.5 years, and their weight rangedbetween 79.5 – 80.3 kg, Rams were randomly divided into 3 equal groups of 5 rams eachgroup. The first group were taken1000 while the second group were taken 2000 gaussmagnetic water, the third group were taken normal streaming water which is considered as a(control group). Blood sample were taken at the beginning of the experiment, and repeatedevery two weeks during the experimental period (four months). Results revealed that treatedthe rams with magnetically treated water resulted in significantly decreased (p<0.01) incholesterol (1.78-4.08), triglycerides (0.94-0.054), low density lipoprotein (LDL) (1.4-0.2),Very low density lipoprotein (VLDL) (1.87-0.14) and significant increase (p<0.01) in highdensity lipoprotein (HDL)(0.17-0.49) .It could be concluded that rams received magneticallytreated water resulted in significant improvement in level of lipid involved in this experiment.

scholarly journals Effect of Magnetic Water on Some Physiological Aspects of Adult Male Rabbits

2012 ◽  
Vol 36 (0E) ◽  
pp. 120-126
Author(s):  
Khalisa Kadim Khudiar
Keyword(s):  
Lipid Profile ◽  
Adult Male ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Total Serum ◽  
Control Group ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Magnetic Water

The present study was undertaken to search out thebeneficial effect of magnetized water on serumantioxidant, lipid profile and total protein of adult male rabbits. Twenty adult male rabbits were randomly divided into two equal groups and were treated daily for 60 days as follows:Group C:Rabbits of this group were allowed to ad libitumsupplyofdrinking water (control group),Group MG:Rabbits of this group were allowed to ad libitum supply of magnetic water.Fasting blood (for 8-12 hrs) samples were drawn by cardiac puncture technique at different times 0, 30 and 60 days of experiment for measuring the following parameters. Serum glutathione concentration (GSH), lipid profile including serum triacylglycerol (TAG), total cholesterol - (TC), high density lipoprotein - cholesterol (HDL-C), low density lipoprotein - cholesterol (LDL-C) and very low density lipoprotein cholesterol - (VLDL-C), total serum protein concentrations (TSP). The result revealed that drinking of magnetic water had beneficial effect on some physiological aspects manifested by a significant elevation in serum GSH, HDL-C and total serum proteins concentration. In addition to significant suppression in serums TC, TAG, LDL-C, and VLDL-C concentrations .In conclusion the results of this study pointed to the prevalence of magnetic water upon normal drinking water in all measures issued.

scholarly journals Lipid Profile in Preeclampsia Patients as Compared to Normal Patient

2020 ◽  
Vol 22 (4) ◽  
pp. 238-242
Author(s):  
Sanita Kayastha ◽  
B Tiwari ◽  
R Subedi
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
College Teaching ◽  
Test Group ◽  
Control Group ◽  
Low Density ◽  
Medical College ◽  
The Mean ◽  
Severity Of The Disease

The main objective of the study was to see the association of dyslipidemia in preeclampsia (PET) as compare to normotensive (NT) patients. It was a descriptive study done in Nepal Medical College Teaching Hospital Department of Obstetrics and Gynecology from April 2019 from April 2020. A total of 75 PET (test group) and 75 NT (control group) in their third trimester were included. Their fasting lipid profile was studied. It was found that triglyceride (TG) and very low density lipoprotein (VLDL) was significantly high among PET group as compared to that of NT patients. The mean TG of PET group was 266.11± 98.61 and the NT group was 187±58.56 (p=0.00) and the mean VLDL of PET group was 46.00±15.31 and NT group was 37.88±12.85 (p=0.001). On the other hand, the total cholesterol (TC), low density lipoprotein (LDL) and high density lipoprotein (HDL) were not significantly different in both the groups. It was also found that with the severity of the disease (Preeclampsia), the level of TG and VLDL increased significantly. Therefore, among the investigation done for PET, we should include lipid profile, especially the TG and VLDL. Furthermore, TG and VLDL should be measured serially (at least once a week) so as to predict the progress of PET and manage the patient accordingly.

scholarly journals Dyslipidemia in Psoriasis: A Case - Controlled Study

2021 ◽  
Vol 19 (2) ◽  
pp. 39-43
Author(s):  
Monique Kafle ◽  
Madhu Gyawlee ◽  
Amit Amatya ◽  
Bhaskar Mohan Meher Kayastha ◽  
Smarika Upadhyaya
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Controlled Study ◽  
Control Group ◽  
Low Density ◽  
Chronic Inflammatory Condition

INTRODUCTION:  Psoriasis is a chronic inflammatory condition of skin which can be associated with other ailments including dyslipidemia which is an abnormal serum lipid profile. OBJECTIVE: The aim of present study was to determine correlation between dyslipidemia and Psoriasis of patients visiting the Out-patient Department of Patan Hospital METHODS: Ninety patients were selected for study. Among them 30 patients with psoriasis were taken as cases and 60 patients that matched for age and sex with Psoriasis patients were taken as controls. The lipid profile that comprised four parameters: serum High-density Lipoprotein, Low-density Lipoprotein, Total Cholesterol and Triglyceride were determined and compared for both case and control groups. RESULTS: More than 95% of the psoriatic patients had dyslipidemia. The odds of dyslipidemia among Psoriatic patients were 1.709 times higher compared to control group (p <0.001). Among the parameters, results showed High-density lipoprotein was significantly lower while Triglyceride was significantly higher among the cases compared to controls with p value of 0.012 and 0.001 respectively. The risk factors like smoking and alcohol were present in higher proportions among the patients with dyslipidemia but it failed to reach statistical significance. With increase in duration of Psoriasis and PASI scores, lipid parameters i.e., Total cholesterol, triglyceride and Low-density lipoprotein increased while High density lipoprotein decreased but this correlation was insignificant. CONCLUSION: This study showed Dyslipidemia is significantly higher among patients with Psoriasis especially lipid profile parameters Triglyceride and total cholesterol. Thus, timely screening and management of dyslipidemia among Psoriatic patients might be helpful in prevention of future cardiovascular events.

scholarly journals Dyslipidemia in subclinical hypothyroidism requires assessment of small dense low density lipoprotein cholesterol (sdLDL-C)

2017 ◽  
Vol 55 (3) ◽  
pp. 159-166
Author(s):  
Maida Seferovic Saric ◽  
Miljenka-Jelena Jurasic ◽  
Slavica Sovic ◽  
Bojana Kranjcec ◽  
Tatjana Glivetic ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Subclinical Hypothyroidism ◽  
Early Stage ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
Ldl Particles

Abstract Background. Usually both hypothyroidism and hyperthyroidism are related to the cardiovascular and cerebrovascular disease development. The relationship between subclinical hypothyroidism has been widely investigated but the findings remain controversial. The aim of the present study was to evaluate the lipid profile in patients with subclinical hypothyroidism (SHypo) in comparison to controls and to determine the association of SHypo and dyslipidemia in attempt to find importance of small dense low-density lipoprotein cholesterol (sdLDL-C) in atherosclerosis. Material and methods. In this study we included 100 women, aged 30 to 70 years that were divided into subgroups according to their age. According to the values of levels of thyroid hormones they were divided into euthyroid (control) group (n = 64) and (newly discovered) subclinical hypothyroidism (SHypo) group (n = 36). A high-sensitivity C-reactive protein (hs-CRP) and lipid profile, including small dense low-density lipoprotein cholesterol (sdLDL-C) were determined. Body weight and height were measured and BMI calculated. History of the current illness, medication, alcohol consumption and cigarettes smoking were noted. Results. Changed lipid profile as well as elevated triglycerides and sdLDL-C were observed in the group with subclinical hypothyroidism compared to the control group. Conclusions. It is important to determine serum lipid levels, especially serum sdLDL-C levels at an early stage of subclinical hypothyroidism, since they represent atherogenic LDL particles and are better indicators for dyslipidaemia in subclinical hypothyroidism and the development of atherosclerosis with potential complications such as cardiovascular and cerebrovascular diseases.

scholarly journals Assessment of Levels of Metabolic Hormones and Lipid Profile in Growth Hormone Deficient Patients

2020 ◽  
pp. 732-741
Author(s):  
Ghada Kh. Al-hindawi ◽  
Makarim Q. Al-Lami ◽  
Abdilkarim Y. Al-Samarriae
Keyword(s):  
Growth Hormone ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Cortisol ◽  
Thyroid Stimulating Hormone ◽  
Control Group ◽  
Low Density ◽  
Metabolic Hormones ◽  
High Level

Abstract The current study aims to evaluate levels of metabolic hormones and lipid profile in a sample of growth hormone (GH) deficient patients. Seventy five GH deficient patients and twenty healthy subjects used as control group have been participated in this study during their attendance to the National Diabetic Center for Treatment and Research/Al-Mustansiriya University. The studied subjects’ ages were with a range (3-15 years). Blood samples were collected from the studied subjects to determine levels of basal GH, GH2 and GH3 after 1 hr and 1/30 hr provocation with clonidine, respectively; insulin like growth factor (IGF-1); levels of metabolic hormones [thyroid profile: triiodothyronine (T3), thyroxin (T4), and thyroid stimulating hormone (TSH)]; and lipid profile [cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL) and very low density lipoprotein (VLDL)]. The findings of the anthropometric measurements of the studied groups revealed that a non-significant (P>0.05) difference was found in the weight between the patients and the control, while the mean of height in the patients was significantly (P<0.05) lower than its value in the control. Mean of BMI detected a non-significant (P>0.05) difference between the patients and the control. While mean of BMI percentile and mean of BMI Z-score revealed significant (P<0.05) decrease in the patients compared to their values in the control. The results showed that non-significant (P>0.05) difference was found in level of basal GH between the patients and the control, while a high significant (P<0.01) decrease was found in levels of GH2 and GH3 in the patients group compared to the control group. Level of IGF-1 showed a significant (P<0.05) decrease in the patients compared to the control. The results of metabolic hormones revealed a non-significant (P>0.05) difference in serum T3 between the patients and the control, while a high significant (P<0.01) decrease was found in serum T4 in the patients compared to the control.  A non-significant (P>0.05) difference was found in serum TSH between the patients and the control. The data of serum cortisol showed a significant (P<0.05) increase in the patients compared to the control. The results of lipid profile showed a non-significant (P>0.05) difference in serum cholesterol between the patients and the control, while triglyceride showed a significant (P<0.05) increase in the patients compared to the control. A non-significant (P>0.05) difference was found in serum HDL between the patients and the control, while a significant (P<0.05) increase was found in levels of LDL and VLDL in the patients compared to the control. It can be concluded from the present study that diagnosis of GHD cannot be done at the basal serum of GH.  A high level of GH was detected after 1 hr. provocation with clonidine compared with its value after 1/30 hr. provocation. The IGF-1 is an appropriate parameter to expect GHD in children and adolescences whom GHD was detected by GH stimulation testing. Low GH secretion is associated with high level of cortisol resulting in GHD.  Patients with GHD displayed a tendency towards lipids disturbances.

scholarly journals MODIFIKASI TAI CHI DAN SENAM JANTUNG SEHAT PADA PROFIL LIPIDA DAN KEBUGARAN PRA LANSIA The Tai Chi Modification (Mtc) And Gymnastics (Senam Jantung Sehat) Upon Lipid Profile And Physical Fitness At Middle Age.

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
M. Zainul Arifin
Keyword(s):  
Physical Fitness ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Tai Chi ◽  
Middle Age ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Randomized Control

Penelitian ini bertujuan untuk menciptakan Modifikasi Tai Chi (MTC) berupa gerakan yang sesuai dan efektif bagi pra lansia dalam hal perbaikan profil lipida dan kebugaran tubuh  disamping Senam Jantung Sehat (SJS). Jenis penelitian ini adalah penelitian eksperimen dengan menggunakan desain Randomized Control Group Pretest Posttest. Populasi penelitian adalah laki-laki pra lansia (40 th s/d 49 th) dan sehat di Puri Mojobaru RW 03, Canggu, Mojokerto berjumlah 300 orang. Melalui rumus Lemeshow ditentukan jumlah sampel 27 orangyang dibagi tiap kelompok 9 orang secara random, ada tiga kelompok yaitu kelompok 1 diberi perlakuan Modifikasi Tai Chi berjumlah 9 orang, kelompok 2 diberi perlakuan Senam Jantung Sehat berjumlah 9 orang dan kelompok 3 adalah kontrol berjumlah 9 orang. Perlakuan pada kelompok Modifikasi Tai Chi dan Senam Jantung Sehat berdurasi 60 menit per latihan, frekuensi 3 x per minggu, selama 8 minggu. Variabel yang akan diukur adalah: 1) total colesterol (TC), 2)trigliserida (TG), 3) low density lipoprotein (LDL), 4) high density lipoprotein (HDL), 5) perbandingan HDL/TC dan kebugaran terdiri atas: 1) kapasitas aerobic maksimal (VO2max), 2) efisiensi ambilan oksigen saat ventilasi (VO2/VE). Data variabel terikat diukur sebelum perlakuan (pretest) dan sesudah perlakuan (posttest). Selanjutnya data diolah menggunakan analisis statistik meliputi : Anova, LSD (α=0,05) dengan menggunakan program komputer SPSS versi 16. Hasil penelitian menunjukkan bahwa : 1) MTC memperbaiki TC (p=0,000, TG (p=0,000), LDL (p=0,005), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,000), VO2/VE (p=0,019). 2) SJS memperbaiki TC (p=0,000), TG (p=0,000), LDL (p=0,005), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,019), VO2/VE(p=0,006). 3) Perbedaan perbaikan profil lipida dan peningkatan kebugaran antara MTC dengan SJS adalah TC(p=0,000), TG (p=0,000), LDL (p=0,000), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,000), VO2/VE (p=0,645) . sehingga diketahui MTC lebih efektif memperbaiki profil lipida dan kebugaran tubuh pra lansia dari pada SJS. Jadi Modifikasi Tai Chi dapat dijadikan sebagai alternatif yang lebih baik dari pada Senam Jantung Sehat dalam hal memperbaiki profil lipida dan meningkatkan kebugaran tubuh, terutama pada pra lansia, walaupun VO2/VE antara MTC dan SJS tidak ada beda.

scholarly journals Effect Of Vêo® Premium and Vitamin C Supplementation on Lipid Profile Before and During Pregnancy in Some Local Iraqi Ewes During Heat Stress

2021 ◽  
pp. 2122-2130
Author(s):  
Othman Ghazi Najeeb Alani ◽  
Yassen Taha Abdul-Rahaman ◽  
Thafer Thabit Mohammed
Keyword(s):  
Heat Stress ◽  
Vitamin C ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Significant Difference ◽  
Vitamin C Supplementation ◽  
Vit C

The present study was designed to investigate the effects of VêO® premium and vitamin C (Vit. C) supplementation on lipid profile before and during pregnancy in local Iraqi ewes during heat stress. The study was conducted in a private field in Fallujah city, west Iraq, during the period from 6/8/2019 to 8/2/2020. Twenty local Iraqi ewes were divided randomly into four equal groups (5 for each group) The first group (T1) was given VêO® premium (4 g/ ewe/ day), the second group (T2) was given VêO® premium (2 g/ ewe/ day), and the third group (T3) was given Vit. C (40 mg/ ewe/ day), and the fourth group (T4) was left without treatment, as a control group. After 14 days of treatment, vaginal sponges were inserted for 14 days and, after their withdrawal, the rams were introduced for 6 days. Blood samples were collected from the jugular vein into vacutainer tubes (10 ml) at 4 periods (periods 1 and 2 before pregnancy; periods 3 and 4 during pregnancy). Lipid profile parameters were also estimated, which includes cholesterol, triglyceride, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), and malondialdehyde (MDA). There were no significant difference in the serum levels of cholesterol, triglyceride, HDL, and LDL among the various treatments before and during pregnancy. The level of VLDL was significantly higher in T2 group as compared to the other treatments (P≤0.05) at the fourth periods. There was a significant difference in the level of MDA (P≤0.05) in treatment T3 in the first period compared with the treatments T1, T2, and T4, whereas treatment T4 showed significantly higher level (P≤0.05) in the second, third, and fourth periods as compared to treatments T1, T2, and T3. In conclusion, different effects of VêO® premium and Vitamin C supplementation were noticed on the lipid profile before and during pregnancy in local Iraqi ewes during heat stress.

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