scholarly journals Deformable Atlases for the Segmentation of Internal Brain Nuclei in Magnetic Resonance Imaging

Author(s):  
Marius George Linguraru ◽  
Miguel Ángel González Ballester ◽  
Nicholas Ayache

Magnetic resonance imaging (MRI) is commonly employed for the depiction of soft tissues, most notably the human brain. Computer-aided image analysis techniques lead to image enhancement and automatic detection of anatomical structures. However, the information contained in images does not often offer enough contrast to robustly obtain a good detection of all internal brain structures, not least the deep grey matter nuclei. We propose a method that incorporates prior anatomical knowledge in the shape of digital atlases that deform to fit the image data to be analysed. Our technique is based on a combination of rigid, affine and non-rigid registration, segmentation of key anatomical landmarks and propagation of the information of the atlas to detect deep grey matter nuclei. The Montreal Neurological Institute (MNI) and Zubal atlases are employed. Results show that detecting important structures such as the ventricles and brain outlines greatly improves the results. Our method is fully automatic.

Foot & Ankle ◽  
1987 ◽  
Vol 8 (3) ◽  
pp. 144-147 ◽  
Author(s):  
Ian J. Alexander ◽  
Kenneth A. Johnson ◽  
Thomas H. Berquist

Magnetic resonance imaging (MRI), a useful technique of studying soft tissues of the body, can be very effective in assessing the integrity of tendons. Usually a patient with a complete tear of the posterior tibial tendon has characteristic physical findings. In the patient presented, MRI demonstrated a complete disruption of the posterior tibial tendon, despite the absence of the commonly associated clinical findings. In view of the difficulties encountered with attempted tenography of the completely torn posterior tibial tendon, MRI provides a sensitive alternative diagnostic technique.


2020 ◽  
Vol 6 (1) ◽  
pp. 205521732090248
Author(s):  
Cecilie Jacobsen ◽  
Robert Zivadinov ◽  
Kjell-Morten Myhr ◽  
Turi O Dalaker ◽  
Ingvild Dalen ◽  
...  

Background Multiple sclerosis is often associated with unemployment. The contribution of grey matter atrophy to unemployment is unclear. Objectives To identify magnetic resonance imaging biomarkers of grey matter and clinical symptoms associated with unemployment in multiple sclerosis patients. Methods Demographic, clinical data and 1.5 T magnetic resonance imaging scans were collected in 81 patients at the time of inclusion and after 5 and 10 years. Global and tissue-specific volumes were calculated at each time point. Statistical analysis was performed using a mixed linear model. Results At baseline 31 (38%) of the patients were unemployed, at 5-year follow-up 44 (59%) and at 10-year follow-up 34 (81%) were unemployed. The unemployed patients had significantly lower subcortical deep grey matter volume ( P < 0.001), specifically thalamus, pallidus, putamen and hippocampal volumes, and cortical volume ( P = 0.011); and significantly greater T1 ( P < 0.001)/T2 ( P < 0.001) lesion volume than the employed patient group at baseline. Subcortical deep grey matter volumes, and to a lesser degree cortical volume, were significantly associated with unemployment throughout the follow-up. Conclusion We found significantly greater atrophy of subcortical deep grey matter and cortical volume at baseline and during follow-up in the unemployed patient group. Atrophy of subcortical deep grey matter showed a stronger association to unemployment than atrophy of cortical volume during the follow-up.


2007 ◽  
Vol 13 (7) ◽  
pp. 880-883 ◽  
Author(s):  
Y. Zhang ◽  
RK Zabad ◽  
X. Wei ◽  
LM Metz ◽  
MD Hill ◽  
...  

T2 hypointensity (black T2, BT2) in the deep grey matter of multiple sclerosis (MS) patients correlate weakly with disability at 1.5 T. BT2 is likely to be caused by abnormal iron deposition. We compared the correlation between disability and deep grey matter BT2 measured on 3 T MRI and on 1.5 T MRI in 17 MS patients. We observed a significant correlation between expanded disability status scale and signal intensity on 3 T MRI in the globus pallidus and the caudate nucleus ( r = —0.5, P < 0.05). BT2 at 3 T may be a useful MRI measure associated with disability in MS and warrants further study. Multiple Sclerosis 2007; 13: 880—883. http://msj.sagepub.com


2019 ◽  
Vol 57 (1) ◽  
pp. 91-99 ◽  
Author(s):  
D. M. Kudinsky ◽  
A. V. Smirnov ◽  
L. I. Alekseeva

The article discusses the possibilities and search for the optimal concept of diagnosis of hand osteoarthritis (OA). The data of numerous studies with focus on the comparison of sensitivity and specificity of the main techniques in this type of pathology – standard radiography and magnetic resonance imaging (MRI) are presented. Determination of the earliest symptoms of OA allows to predict the development of the disease and begin its therapy. The joint space narrowing due to the loss of articular cartilage is the earliest radiological symptom of OA, which is observed in the advanced stage of the disease. MRI, unlike radiography, makes it possible to visualize the articular cartilage, fluid in the joint cavity, bone marrow edema and soft tissues, but it is more expensive and time-consuming method. At present the main difficulty lies in the absence of a standardized system for assessing the MRI hand OA manifestations, as well as insufficient number of investigations in this area.


2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Min Gu ◽  
Fabio Savoldi ◽  
Urban Hägg ◽  
Colman P. J. McGrath ◽  
Ricky W. K. Wong ◽  
...  

Objective. The present study compared the changes in the upper airway dimensions and sleep-related breathing disorder (SRBD) condition between functional treatment with the headgear Herbst (HG-Herbst) and headgear Twin Block (HG-TB) appliance. Soft tissues were assessed on lateral cephalometric X-ray and magnetic resonance imaging (MRI). Materials and Methods. Consecutive patients who sought orthodontic treatment at the Faculty of Dentistry of The University of Hong Kong were screened. Adolescents (12-17 year sold for boys and 10-15 years old for girls), with class II molar relationship and overjet >5 mm, with no severe transverse maxillary deficiency, were recruited. Patients were assigned either to the HG-Herbst or to the HG-TB treatment by stratified block randomisation, with sex as the stratification factor. Lateral cephalograms, magnetic resonance imaging (MRI), and the Paediatric Sleep Questionnaire (PSQ) were obtained at baseline and after treatment. Results. 28 patients were enrolled, and 26 patients (13 in each group) completed the treatment. Following 1 year of functional appliance treatment, a significantly lower increase of the lower anterior facial height was observed in the HG-Herbst group compared to the HG-TB group (p = 0.024). However, no significant differences were observed in the upper airway structures or SRBD between the two groups. Conclusion. The changes in upper airway dimensions and SRBD condition were not significantly different between the HG-Herbst and the HG-TB appliance treatment. Additional studies with larger sample size are warranted.


1997 ◽  
Vol 78 (6) ◽  
pp. 439-441
Author(s):  
A. T. Valiullina ◽  
L. M. Tukhvatullina ◽  
R. F. Bakhtiozin ◽  
I. R. Chuvashaev

Magnetic resonance imaging (MRI) has become one of the leading methods of noninvasive diagnostics in the last 10 years. Interest in this type of examination is due to its great potential possibilities: absence of radiation exposure, high natural tissue contrast, obtaining sections of any orientation, possibility of multiple examination and dynamic control, determining not only the anatomical structure of soft tissues, but also their chemical composition.


2008 ◽  
Vol 12 (3) ◽  
pp. 77
Author(s):  
S Reddy ◽  
E Rudakemwa ◽  
M Modi

Schizencephaly is a rare CNS malformation consisting of a full-thickness CSF filled parenchymal cleft lined by grey matter (3). Schizencephaly can be diagnosed on prenatal ultrasound but requires magnetic resonance imaging (MRI) for more specific diagnostic differentiation from other cerebro-spinal fluid (CSF) containing structures as well as for detection of associated features (3).


2020 ◽  
Author(s):  
Renée Hartig ◽  
Daniel Glen ◽  
Benjamin Jung ◽  
Nikos K. Logothetis ◽  
George Paxinos ◽  
...  

AbstractDigitized neuroanatomical atlases are crucial for localizing brain structures and analyzing functional networks identified by magnetic resonance imaging (MRI). To aid in MRI data analysis, we have created a comprehensive parcellation of the rhesus macaque subcortex using a high-resolution ex vivo structural imaging scan. The structural scan and its parcellation were warped to the updated NIMH Macaque Template (NMT v2), an in vivo population template, where the parcellation was refined to produce the Subcortical Atlas of the Rhesus Macaque (SARM). The subcortical parcellation and nomenclature reflect those of the 4th edition of the Rhesus Monkey Brain in Stereotaxic Coordinates (RMBSC4; Paxinos et al., in preparation). The SARM features six parcellation levels, arranged hierarchically from fine regions-of-interest (ROIs) to broader composite regions, suited for fMRI studies. As a test, we ran a functional localizer for the dorsal lateral geniculate (DLG) nucleus in three macaques and found significant fMRI activation in this atlas region. The SARM has been made openly available to the neuroimaging community and can easily be used with common MR data processing software, such as AFNI, where the atlas can be embedded into the software alongside cortical macaque atlases.HighlightsWe present the Subcortical Atlas of the Rhesus Macaque (SARM).SARM provides a neuroanatomical reference frame for neuroimaging analysis.The entire subcortex is mapped, including the thalamus, basal ganglia, and brainstem.ROIs are grouped hierarchically, making SARM useful at multiple spatial resolutions.SARM is in the NMT v2 template space and complements the CHARM atlas for the cortex.


Author(s):  
Gonzalo André Montesinos ◽  
Rosa Cristina Peinado Agudo ◽  
André Camilo de Oliveira ◽  
André Antonio James ◽  
Jefferson Xavier Oliveira ◽  
...  

Magnetic resonance imaging is effective to diagnose some diseases that affect the temporomandibular joint (TMJ) of children. The images allow the detection of early stages of juvenile idiopathic arthritis, cases of joint ankylosis and is currently considered the most reliable exam for an objective and noninvasive assessment of intracapsular soft tissues. The objective of this literature review was to assess some of the temporomandibular joint changes in children using magnetic resonance imaging (MRI). The assessment of TMJs of children performed through MRI make the diagnosis more accurate and objective. Detecting alterations during the early stages of juvenile idiopathic arthritis using 3T MRI devices is possible utilizing contrast tools, which as a result, provides better prognosis and treatment.


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