scholarly journals Diagnosis and medical treatment of neuropathic pain in leprosy

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Rogerio Del Arco ◽  
Susilene Maria Tonelli Nardi ◽  
Thiago Gasperini Bassi ◽  
Vania Del Arco Paschoal

ABSTRACT Objective: to identify the difficulties in diagnosing and treating neuropathic pain caused by leprosy and to understand the main characteristics of this situation. Methods: 85 patients were treated in outpatient units with reference to leprosy and the accompanying pain. We used a questionnaire known as the Douleur Neuropathic 4 test and we conducted detailed neurological exams. As a result, 42 patients were excluded from the study for not having proved their pain. Results: Out of the 37 patients that experienced pain, 22 (59.5%) had neuropathic pain (or a mixture of this pain and their existing pain) and of these 90.8% considered this pain to be moderate or severe. 81.8% of the sample suffered with this pain for more than 6 months. Only 12 (54.5%) of the patients had been diagnosed with neuropathic pain and in almost half of these cases, this pain had not been diagnosed. With reference to medical treatment (n=12) for neuropathic pain, 5 (41.6%) responded that they became better. For the other 7 (58.4%) there were no changes in relation to the pain or in some cases the pain worsened in comparison to their previous state. Statistical analysis comparing improvements in relation to the pain amongst the patients that were treated (n=12) and those that were not, showed significant differences (value p=0.020). Conclusion: we noted difficulties in diagnosing neuropathic pain for leprosy in that almost half of the patients that were studied had not had their pain diagnosed. We attributed this to some factors such as the non-adoption of the appropriate protocols which led to inadequate diagnosis and treatment that overlooked the true picture.

2021 ◽  
Vol 9 ◽  
Author(s):  
Samil Hizli ◽  
Demet Can ◽  
Ilknur Kiliç ◽  
Emel Örün ◽  
Turan Tunç ◽  
...  

Background and Objective: Due to limited knowledge on the etiopathogenesis of infantile colic (IC) and the insufficiency of data regarding current treatments, different approaches emerge in terms of diagnosis, and treatment modalities globally and also in Turkey. The objective of this study was to observe how infantile colic is diagnosed and treated by paediatricians in Turkey.Methods: An anonymous electronic questionnaire was used to collect the respondents' opinions. The study questionnaire was comprised of 4 different sections with 56 multiple-choice questions covering demographic features, diagnostic approach, treatment preferences and response to treatment.Results: A total of 375 paediatricians responded to the survey. Fifty three percent of the participants stated that they established the IC diagnosis based only on their clinical experience. Factors that most affected the decision to start treatment were identified as parent discomfort, decreased family quality of life, and crying duration (68, 66, and 54%, respectively). Application of soothing methods, probiotics, and simethicone were identified as the most frequently used treatment modalities (frequency ranking; 81, 76, and 50%, respectively). Of the participants, 98% stated that they used probiotic as supplements, on the other hand, 72% of the participants indicated that they used simethicone as the only medical treatment to treat IC. The question about the participants' observations regarding the response to probiotic treatment was answered by 71% of the participants with decreased crying duration, while easier stool/gas passage and resolved digestion problems were the other frequent observations (54 and 49%, respectively). The observations related to the response to simethicone treatment also included decreased crying duration in addition to decreased crying periods after feeding and easier gas/stool passage (67, 47, and 44%, respectively).Conclusions: Survey results revealed that the majority of the paediatricians used their clinical experience alone to establish the diagnosis of IC and preferred probiotic supplements and simethicone as the only medical treatment to treat IC and they observed clinical benefits from them. Insights generated by this study will be helpful to guide future efforts to improve the management of infantile colic by paediatricians.


2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Omnia A. Elhiny ◽  
Mohammed Abou Elyazied ◽  
Ghada A. Salem

Abstract Background The choice between extraction and expansion treatment is an endless debate in orthodontics. Ethnic and secular variations showed that there was a change in  arch perimeter over the last 50 years. Accordingly, the purpose of this study was to investigate the relation between the arch perimeter and the intercanine and intermolar widths in normal occlusion. Also, to design regression equations for the prediction of the arch perimeter based on arch width, in a sample of the Egyptian population. The images of 340 cast pairs for 11 to 13-year-old patients were traced using TracerNet. Intercanine width, intermolar width and arch perimeter were measured, statistical analysis was performed and regression equations for both arches were formulated. Results There was a positive correlation between the lower arch AP, ICW and IMW and between the upper arch AP and ICW. Lower arch perimeter = 0.536 I33 + 71.642, lower arch perimeter = 0.828 l66 + 58.604 and upper arch perimeter = 1.988 U33 + 30.492 were the significant derived equations. Conclusions The formulation of regression equations offers a tool for the prediction of arch perimeter or arch width that can act as a guide in diagnosis and treatment planning.


Complexity ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Helbert Eduardo Espitia ◽  
Iván Machón-González ◽  
Hilario López-García ◽  
Guzmán Díaz

Systems of distributed generation have shown to be a remarkable alternative to a rational use of energy. Nevertheless, the proper functioning of them still manifests a range of challenges, including both the adequate energy dispatch depending on the variability of consumption and the interaction between generators. This paper describes the implementation of an adaptive neurofuzzy system for voltage control, regarding the changes observed in the consumption within the distribution system. The proposed design employs two neurofuzzy systems, one for the plant dynamics identification and the other for control purposes. This focus optimizes the controller using the model achieved through the identification of the plant, whose changes are produced by charge variation; consequently, this process is adaptively performed. The results show the performance of the adaptive neurofuzzy system via statistical analysis.


1989 ◽  
Vol 25 (1) ◽  
pp. 11-25
Author(s):  
D. J. Finney

SUMMARYObservations that are frequencies rather than measurements often call for special types of statistical analysis. This paper comments on circumstances in which methods for one type of data can sensibly be used for the other. A section on two-way contingency tables emphasizes the proper role of χ2 a test statistic but not a measure of association; it mentions the distinction between one-tail and two-tail significance tests and reminds the reader of dangers. Multiway tables bring new complications, and the problems of interactions when additional classificatory factors are explicit or hidden are discussed at some length. A brief outline attempts to show how probit, logit, and similar techniques are related to the analysis of contingency tables. Finally, three unusual examples are described as illustrations of the care that is needed to avoid jumping to conclusions on how frequency data should be analysed.


2000 ◽  
Vol 5 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Allan S Gordon

Practitioners are often presented with patients who complain bitterly of facial pain. The trigeminal nerve is involved in four conditions that are sometimes mixed up. The four conditions - trigeminal neuralgia, trigeminal neuropathic pain, postherpetic neuralgia and atypical facial pain - are discussed under the headings of clinical features, differential diagnosis, cause and treatment. This article should help practitioners to differentiate one from the other and to manage their care.


1984 ◽  
Vol 41 (6) ◽  
pp. 985-988 ◽  
Author(s):  
A. H. El-Shaarawi ◽  
M. A. Neilson

Water samples were collected on Lake Ontario during April and November, filtered (0.45 μm), and immediately analyzed onboard ship for the nutrients soluble reactive phosphorus, nitrate-plus-nitrite, and ammonia. Replicates were stored in glass bottles at 4 °C and reanalyzed within 8 d. Statistical analysis showed that soluble reactive phosphorus decreased by 11 and 13% and nitrate-plus-nitrite by 7 and 6%, whereas ammonia increased by 75% on one cruise and decreased by 37% on the other.


2021 ◽  
pp. 8-12
Author(s):  
I. V. Kuznetsova

Endometriosis is a common disease, the diagnosis and treatment of which is still a matter of debate. One of the main symptoms of endometriosis -pelvic pain is a particular problem due to the difficulties in identifying the cause and the lack of sufficient effect from surgical and medical treatment. The literature review presents current data on the prevalence, clinical characteristics and methods of individualized therapy in patients with pelvic pain established or presumably associated with endometriosis.


2018 ◽  
Vol 4 (1) ◽  
pp. e000366 ◽  
Author(s):  
Joseph Alexander Nathan ◽  
Kevin Davies ◽  
Ian Swaine

ObjectiveTo determine whether there is an association between hypermobility and sports injury.MethodsA quantitative observational approach using a cross-sectional survey was adopted. Individuals were identified as hypermobile or not. All participants were asked to complete two questionnaires: one asking demographic information and the other injury-specific. Fisher’s exact test was used for statistical analysis.Results114 individuals participated in the study, 62 women and 52 men. 26% of the participants were hypermobile. There was no significant association between hypermobility and sports injury (p=0.66). There was a significant increase in joint and ligament sprain among the non-hypermobile (NH) group covering all sports (p=0.03). Joint dislocation was found exclusively among hypermobile individuals. The duration of injury in hypermobile individuals was higher than NH. The use of oral painkillers or anti-inflammatories in the semiprofessional group was greater than the general population.ConclusionHypermobility is relatively common among individuals, and there is a lot of anecdotal evidence associating it with increased rates of injuries. This project finds that NH individuals are more likely to sustain a ligament or joint sprain in sports. This is due to increased joint laxity and flexibility preventing injury. There were important limitations to this study which will be addressed in further work. These include assessing for pauciarticular hypermobility and focusing on one sport to investigate its association with sports injury in those who are hypermobile or not. It would also be important to focus on one specific joint, assessing its flexibility and association with injury.


2015 ◽  
Vol 5 (2) ◽  
pp. 114
Author(s):  
Chiu-Fan Hsieh ◽  
You-Qing Zhu

<p class="1Body">This study analyzes the influence of design parameters on the dynamics of straight bevel gears by constructing a model that allows variation in the shaft angle, pressure angle, and backlash. According to the statistical analysis, the order of influence of these parameters on weight is shaft angle &gt; pressure angle &gt; backlash. When the shaft angle is 90°, the statistical results show the drive is stable and the stress fluctuation level is low. The pressure angle, on the other hand, can affect the gear’s dynamic property by influencing the driving component force on the gear and the component force on the shaft. The results for the shaft and pressure angles are used to determine the appropriate backlash. Overall, the analysis not only provides designers with an important reference but explains the dominance in the market of gear designs with a 90° shaft angle and a 20° pressure angle.</p>


1941 ◽  
Vol 1 (1) ◽  
pp. 26-41 ◽  
Author(s):  
Simon Kuznets

This paper deals with the relation between statistical analysis as applied in economic inquiry and history as written or interpreted by economic historians. Although both these branches of economic study derive from the same body of raw materials of inquiry—the recordable past and present of economic society—each has developed in comparative isolation from the other. Statistical economists have failed to utilize adequately the contributions that economic historians have made to our knowledge of the past; and historians have rarely employed either the analytical tools or the basic theoretical hypotheses of statistical research. It is the thesis of this essay that such failure to effect a close interrelation between historical approach and statistical analysis needs to be corrected in the light of the final goal of economic study.


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