Speech production assessment of mouth breathing children with hypertrophy of palatines and/or pharyngeal tonsils

ABSTRACT Objective: to evaluate the speech sound production of children diagnosed with a palatine mouth breathing and / or hypertrophic pharyngeal tonsil and compare it to that of a group of children that do not show any respiratory alterations, besides associating with age and sex. Methods: a quantitative, cross-sectional, analytical and observational research. Children from five to twelve years old have took part of the study, 50 of them diagnosed as mouth breathers (research group - RG) and 50 with no respiratory alteration (control group - CG). Anamnesis and evaluation based on MBGR protocol was performed, focusing on the speech, supported by figures and with samples of automatic and spontaneous speech. Results: there were no differences between the groups, taking into account the parents' complaint. Speech alterations, such as phonetic deflection, lingual interposition and distortions, and occlusion alterations were more frequent in RG. Speech alterations prevailed for males in 83% and the average age related to speech did not show any significance. Conclusion: mouth breathing children present more alterations of speech sounds than those presented with no respiratory alteration, regardless of the age group, being more common in male children.

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COMPARATIVE EVALUATION OF SPIROMETRY PARAMETERS IN HEALTHY YOUNG AND ELDERLY ADULTS POPULATION IN PUNJAB, INDIA

10.36106/ijar/5406276 ◽

2021 ◽

pp. 1-3

Author(s):

Ajay Pal Singh ◽

Kailash Meena ◽

Surinder Pal Singh ◽

Avnish Kumar ◽

Ashish Shukla ◽

...

Keyword(s):

Pulmonary Function ◽

Tertiary Care ◽

P Value ◽

Pulmonary Medicine ◽

Care Hospital ◽

Age Group ◽

Elderly Adults ◽

Elderly Age ◽

Cross Sectional ◽

Age Related

INTRODUCTION: Spirometry is a vital tool for the assessment of pulmonary function status. Spirometry can be used to demonstrate the age-related decline in pulmonary function. The spirometry values can be used as reference values for a particular age group. The aims of our study was to compare spirometry values between the young and elderly groups and evaluate age-related changes in both groups. MATERIAL AND METHODS: A cross-sectional study was conducted on 600 adults, which divided into two healthy groups: one was of young adults (18-35 years), and other was of elderly adults (>60 years) of 300 persons, each taken over a period of one year, in the Department of pulmonary medicine, a tertiary care hospital, Punjab. We conducted spirometry in both age group. Spirometry values were measured FVC, FEV1, FVC/FEV1, PEFR, and FEF25- 75 % of each groups.The subjects were selected based on random sampling RESULT: Spirometry values compared between young and elderly adults. Mean BMI in young and elderly groups was 25.09±2.87 and 25.82±2.45, respectively. Spirometry values in FVC , FEV1, FEV1/FVC , PEFR and FEF25-75% in young was 4.31± 0.18 , 3.84,± 0.88± 0.02, 9.87± 0.38 and 3.75 ±0.26 and elderly age group 3.01±, 2.60 ±0.85± 0.02, 7.70± 0.30 and 2.82 ± 0.26. On statistical analysis, p value <0.001 in all spirometry parameters. CONCLUSION: The study shows that there was a decline in spirometry parameters of healthy adults with the increase in age. This decline was signicant in all spirometric parameters (FVC, FEV1, FEV1/FVC, PEFR, FEF25–75%) measured in the present study

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Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina

Epidemiology and Infection ◽

10.1017/s0950268819001936 ◽

2019 ◽

Vol 147 ◽

Cited By ~ 1

Author(s):

S. García Martí ◽

F. Augustovski ◽

L. Gibbons ◽

V. Loggia ◽

A. Lepetic ◽

...

Keyword(s):

Economic Value ◽

Interrupted Time Series ◽

Medical Costs ◽

Control Group ◽

Rotavirus Vaccine ◽

Age Group ◽

Real World Data ◽

San Luis ◽

Age Related ◽

Vaccine Impact

Abstract Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20–25% and a reduction in AGE-related hospitalisations of 55–60%. The vaccine impact was similar for each age group considered (<1 year, <2 years and <5 years). RV vaccination was estimated to have reduced direct medical costs in the province by about 4.5 million pesos from May 2013 to December 2014. Similar to previous studies, we found a higher impact of RV vaccination in preventing severe all-cause AGE cases requiring hospitalisation than in preventing all-cases AGE cases presenting for medical care. An assessment of the economic value of RV vaccination could take other benefits into account in addition to the avoided medical costs and the costs of vaccination.

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Sex- and age-related differences in bilirubin concentrations in serum.

Clinical Chemistry ◽

10.1093/clinchem/30.8.1380 ◽

1984 ◽

Vol 30 (8) ◽

pp. 1380-1382 ◽

Cited By ~ 31

Author(s):

P Rosenthal ◽

M Pincus ◽

D Fink

Keyword(s):

Serum Bilirubin ◽

Pearson Correlation ◽

Age Groups ◽

Correlation Coefficients ◽

Bile Pigment ◽

Age Group ◽

Age Related ◽

Liver Functions ◽

Males And Females ◽

Age And Sex

Abstract The relation between age and sex and the concentration of bilirubin in serum was evaluated in 6740 men and 11 215 women, ages 13 to 96 years. Mean serum bilirubin concentrations in the men significantly exceeded values in the women over all age groups examined. Further, mean serum bilirubin concentrations were greatest both in males and females in the 19-24 years age group and then declined to former values, which persisted throughout life. Pearson correlation coefficients for bilirubin with liver function indices (albumin and total protein) and with hemoglobin were low in all ages and in both sexes, suggesting that bilirubin concentrations do not correlate with those liver functions not directly concerned with bile pigment processing.

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Disability Onset among Aging Canadians: Evidence from Panel Data

Canadian Journal on Aging / La Revue canadienne du vieillissement ◽

10.1017/s0714980800000696 ◽

2002 ◽

Vol 21 (1) ◽

pp. 117-136 ◽

Cited By ~ 2

Author(s):

Derek Hum ◽

Wayne Simpson

Keyword(s):

Panel Data ◽

Control Group ◽

Unique Contribution ◽

Age Group ◽

Income Dynamics ◽

Cross Sectional ◽

Data Set ◽

Disability Status ◽

Before And After ◽

And Gender

ABSTRACTPast studies of aging and disability have been restricted to and by cross-sectional data. When cross-sectional surveys measure income, disability status and age at a common point in time, it is impossible to discern the process, and consequences, of a disability onset. In other words, it is not possible to examine the circumstances of the same individuals before, and after, the disability onset; nor whether effects differ according to the age at which the disability occurs. The present study uses a new panel data set, the Survey of Labour and Income Dynamics (SLID), to examine the prevalence of disability with respect to age, gender, and other socio-economic characteristics; however, its unique contribution is its investigation of disability onset, and the rates of entry into, and exit from, disability status by age group and gender. Further, we assess the financial circumstances of those who become disabled vis-à-vis a “control group”.

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Decreased Pain Threshold in Juvenile Idiopathic Arthritis: A Cross-sectional Study

The Journal of Rheumatology ◽

10.3899/jrheum.120793 ◽

2013 ◽

Vol 40 (7) ◽

pp. 1212-1217 ◽

Cited By ~ 30

Author(s):

Anne Leegaard ◽

Johanne Jeppesen Lomholt ◽

Mikael Thastum ◽

Troels Herlin

Keyword(s):

Juvenile Idiopathic Arthritis ◽

Pain Threshold ◽

Pain Perception ◽

Negative Control ◽

Control Group ◽

Healthy Children ◽

Cross Sectional ◽

Age Related ◽

Digital Pressure ◽

Pressure Algometer

Objective.To examine the pain threshold in children with juvenile idiopathic arthritis (JIA) compared with healthy children by using a digital pressure algometer.Methods.Fifty-eight children with JIA born between 1995 and 2000 and 91 age-related healthy children participated in the study. We used a digital pressure algometer to measure the pain threshold on 17 symmetric, anatomically predefined joint-related or bone-related areas. All children were asked to rate their current pain on a Faces Pain Scale, and parents of children with JIA were asked to complete a parental revised version of the Child Health Assessment Questionnaire (CHAQ-R). Clinical data were registered on children with JIA.Results.The pain threshold was significantly lower among children with JIA (total mean PT = 1.33 ± 0.69 kg/cm2) when compared with the healthy control group (total mean PT = 1.77 ± 0.67 kg/cm2). The same pattern was found in all areas measured, including negative control areas that are normally unaffected in JIA (p = 0.0001 to 0.005). Overall, the pain threshold was 34% lower in females than in males in both groups (p < 0.0001). We found no correlation between pain threshold and age, current pain experience, disease duration, or disease activity.Conclusion.Children with JIA had a substantially lower pain threshold even in areas usually unaffected by arthritis. Our findings suggest that JIA alters the pain perception and causes decreased pain threshold.

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Cross-sectional and prospective study on anti-Müllerian hormone changes in a cohort of pre-menopausal women with a history of differentiated thyroid cancer

Thyroid Research ◽

10.1186/s13044-020-0075-z ◽

2020 ◽

Vol 13 (1) ◽

Cited By ~ 1

Author(s):

Miranda Mittica ◽

Andrea Dotto ◽

Martina Comina ◽

Marsida Teliti ◽

Eleonora Monti ◽

...

Keyword(s):

Thyroid Cancer ◽

Prospective Study ◽

Differentiated Thyroid Cancer ◽

Chronological Age ◽

Control Group ◽

Cross Sectional ◽

Age Related ◽

History Of ◽

Group 3 ◽

Group 2

Abstract Background Anti-Müllerian hormone (AMH) decreases acutely after post-surgical radioactive iodine (RAI) ablation in females with differentiated thyroid cancer (DTC). Aim We performed a cross-sectional and prospective study on AMH levels in pre-menopausal females with a history of DTC. Methods Fifty-nine females after surgery and RAI (group 1) and 30 females after surgery alone (group 2) were studied. The control group consisted of 141 healthy women (group 3). The prospective study was performed in 43 and 14 females from groups 1 and 2, respectively. Results On first evaluation, AMH levels were similar in groups 1 and 2, but lower than in group 3. In all groups, AMH was negatively related with chronological age and FSH levels. When subjects were stratified according to age, AMH levels were not different between groups. When AMH was evaluated up to 2 years after the baseline evaluation, no changes emerged in either group of women with DTC. In the prospective study, the incidence of abnormal menstrual cycles and the onset of menopause were observed in similar percentages of women with a history of RAI-treated DTC and of those treated with surgery alone. Conclusions AMH can be considered a reliable index of ovarian reserve in women with DTC. Chronological age is the main factor influencing AMH levels in both DTC patients and controls. After age-related stratification, AMH levels are similar in women with DTC treated with RAI and those treated with surgery alone.

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Mode of use by mobile phone and change of time of simple audio-motor reaction for users of mobile communication. Age related features of ipsilateral and contralateral effects

Biomedical Radioelectronics ◽

10.18127/j15604136-202101-05 ◽

2021 ◽

Author(s):

N.I. Khorseva ◽

O.R. Al’-Kudri ◽

P.E. Grigoryev ◽

R.I. Islyamov ◽

N.Yu. Shulzhenko

Keyword(s):

Electromagnetic Radiation ◽

Mobile Phone ◽

Auditory System ◽

Age Groups ◽

Control Group ◽

Age Group ◽

Motor Reaction ◽

Age Related ◽

Contralateral Effect ◽

Contralateral Effects

By analysing the time of a simple auditory-motor reaction with mono-presentation of an audio signal, the effect of the electromagnetic radiation of a mobile phone on the human auditory system is evaluated. Regularities in the frequency of occurrence of ipsi and contralateral effects in mobile users of different age groups are obtained. This study has no analogues in either Russian or foreign publications and is currently exclusive. The purpose was to study age-related features of the severity of ipsi and contralateral effects, depending on the mode of use of the mobile phone. To record the ipsi- and contralateral effects, we used the differences in the average values of a simple auditory-motor reaction between the left and right ears with mono-presentation of the sound signal of 573 respondents of different age groups. The obtained values were compared with the control group data for each age group (491 respondents). If the difference was greater than in the control group, the ipsilateral or contralateral effect was recorded. The severity of the effect was evaluated taking into account the lateral preferences of each participant in the experiments (to which ear the mobile phone is most often held) and the mode of use of the mobile phone. Statistical processing of the results was carried out using the non-parametric Mann-Whitney test and the method of descriptive statistics: prevalence indicator (Pr) (relative frequency of manifestation of a particular attribute in the sample). The comparison of the severity of ipsi and contralateral effects for different age groups allowed us to establish the following patterns. It was found that, in general, the manifestation of the contralateral effect decreases with age, and the ipsilateral effect increases. However, this change is not linear. It is shown that the features of the manifestation of the contralateral and ipsilateral effect for each age group depend both on the time of daily use of a mobile phone and on the total duration of use of a mobile phone. We believe that when studying multidimensional input data, an individual approach is necessary. The presented results confirm the negative effect of the radiation of mobile phones on the auditory system, primarily of our younger generation. Given the special vulnerability of children to physical environmental factors and the depth of penetration of EMR MT into the brain of a child, we believe that from a radiobiological point of view, there is already a need to develop a special SanPiN (sanitary rules and norms) for all available modern low-intensity sources of electromagnetic radiation, including Wi-Fi.

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Serum levels of ARMS2, COL8A1, RAD51B, and VEGF and their correlations in Age-Related Macular Degeneration

Current Neurovascular Research ◽

10.2174/1567202618666210531130711 ◽

2021 ◽

Vol 18 ◽

Author(s):

Priya Battu ◽

Kaushal Sharma ◽

Manjari Rain ◽

Ramandeep Singh ◽

Akshay Anand

Keyword(s):

Macular Degeneration ◽

Serum Levels ◽

Cross Sectional Study ◽

Statistical Correlation ◽

Age Related Macular Degeneration ◽

Enzyme Linked Immunosorbent Assay ◽

Control Group ◽

Cross Sectional ◽

Age Related ◽

Study Results

Background: Many factors including genetic and environmental are responsible for the incidence of age-related macular degeneration (AMD). However, its pathogenesis has not been clearly elucidated yet. Objective: This study aimed to estimate the Age-Related Maculopathy Susceptibility 2 (ARMS2), Collagen type VIII Alpha 1 chain (COL8A1), Rad 51 paralog(RAD51B), and Vascular Endothelial Growth Factor (VEGF) protein levels in serum of AMD and control participants and to further investigate their correlation to understand AMD pathogenesis. Methods: For this cross-sectional study, 31 healthy control and 57 AMD patients were recruited from Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India. A blood sample was taken and serum was isolated from it. ELISA(enzyme-linked immunosorbent assay)was used for the estimation of proteins in the serum of patients. Results: ARMS2 and COL8A1 levels were significantly elevated in the AMD group than in the control group. The highest levels of ARMS2, COL8A1, and VEGF proteins were recorded for the wet AMD sub-group. The study results endorsed significant positive correlation between these following molecules; ARMS2 and COL8A1 (r=0.933, p<0.0001), ARMS2 and RAD51B (r=0.704, p<0.0001), ARMS2 and VEGF (r=0.925, p<0.0001), COL8A1 and RAD51B (r=0.736, p<0.0001), COL8A1 and VEGF (r=0.879, p<0.0001),and RAD51B and VEGF (r=0.691, p<0.0001). Conclusion: The ARMS2 and COL8A1 levels were significantly higher and RAD51B was significantly lower in the AMD group than controls. Also, a significant statistical correlation was detected between these molecules, indicating that their interaction may be involved in the pathogenesis of AMD.

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Age- and Sex-Related Changes in Labial Dimensions of Sudanese Youngs of Arab Descent: A Three-Dimensional Cross-Sectional Study

Children ◽

10.3390/children8070574 ◽

2021 ◽

Vol 8 (7) ◽

pp. 574

Author(s):

Claudia Dolci ◽

Fadil Elamin ◽

Daniele M. Gibelli ◽

Luisa Barni ◽

Alessandra Scolaro ◽

...

Keyword(s):

Growth And Development ◽

Age Groups ◽

Three Dimensional ◽

Width Ratio ◽

Cross Sectional ◽

Age Related ◽

Small Effect Size ◽

Mouth Width ◽

Arab Descent ◽

Age And Sex

Proper evaluation of facial features during growth and development requires the knowledge of anthropometric reference values validated for ethnicity, sex and age. In order to provide information concerning the normal sex-related size of the lips during childhood and young adulthood in Sudanese people of Arab descent, the three-dimensional coordinates of nine labial soft tissue landmarks were obtained by a laser scanner in 332 male and 386 female healthy Northern Sudanese subjects aged 3–30 years. Six labial linear distances, the vermilion height to mouth width ratio, vermilion areas and lip volumes were calculated and averaged for age and sex. Comparisons were performed by factorial analysis of variance (p < 0.01). All labial dimensions significantly increased with age. Significant effects of sex were found for four measurements only, with very small effect size; nonetheless, lips and their parts grew faster in females than in males at almost all ages. Philtrum width was the first linear distance that attained adult values. The vermilion height to mouth width ratio was nearly constant across the age groups. Data collected in this study contribute to information about ethnic-specific lip morphology during growth and development. As orolabial features change over time with their own pattern, the relevant age-related trends should be properly considered for clinical treatment planning.

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Serum zinc and copper levels: a marker of disease activity in senile cataract patients

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20173588 ◽

2017 ◽

Vol 5 (8) ◽

pp. 3697

Author(s):

Pooja S. K. Rai ◽

Smita A. Deokar ◽

Ravi R. Yadav ◽

Sudarshan Shelke ◽

Shimi Sundharan

Keyword(s):

Lipid Membranes ◽

Serum Zinc ◽

Serum Copper ◽

Senile Cataract ◽

Peroxyl Radicals ◽

Control Group ◽

Age Group ◽

Copper And Zinc ◽

Age Related ◽

Cataract Patients

Background: The present study was aimed to study alterations in levels of zinc and copper in senile cataract patients.Methods: 25 senile cataract patients in age group of 50 to 80 years and 25 control group were included in the study. Serum zinc and copper levels were determined by colorimetric method.Results: Significantly increased levels of serum zinc in cataract patients (199.8±24.32 µg/dl) were found as compared to controls (85.80±3.6 µg/dl) (p<0.0001). Serum copper concentration in cataract patients (249.5±34.59 µg/dl) were significantly (<0.0001) increased when compared to controls (125.7±4.66 µg/dl).Conclusions: Copper and zinc are involved in the pathogenesis of cataracts by different mechanisms such as damaging lipid membranes and lens capsule, crosslinking and in solubilization of lens proteins, leakage of beta and gamma crystalline into the aqueous humour through the production of hydroxyl radicals and peroxyl radicals. So, abnormal elevation of serum copper and zinc can be used as a marker in the opacification of the lens cortex in age-related human cataract.

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