scholarly journals Usefulness of argyrophilic nucleolar organizer regions in detection of lung cells alterations after benzo[a]pyrene instillation

2006 ◽  
Vol 21 (suppl 4) ◽  
pp. 36-39 ◽  
Author(s):  
Baldomero Antonio Kato da Silva ◽  
Iandara Schettert Silva ◽  
Daniel Martins Pereira ◽  
Ricardo Dutra Aydos ◽  
Paulo de Tarso Camillo de Carvalho
Keyword(s):  
Statistical Tests ◽  
Nucleolar Organizer ◽  
Lung Cells ◽  
Nucleolar Organizer Regions ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean ◽  
Pulmonary Instillation ◽  
The Relationship ◽  
Argyrophilic Nucleolar Organizer Regions

PURPOSE: To verify the relationship between AgNOR expression and lung tissues changes of Wistar rats after pulmonary instillation of benzo[a]pyrene (B[a]P). METHODS: Male Rattus norvegicus albinus,Wistar lineage were given a single intrapulmonary instillation of B[a]P at doses of 10 and 20 mg/kg in a volume of approximately 0,3 ml. After 7 and 21 days the rats were killed and the lung slices submitted to a histological technique of AgNOR. AgNOR dots were quantified and the result analyzed by statistical tests; p <= 0,05 was considered significant. RESULTS: The mean values of AgNOR dots for the experimental groups 10/7 (1,51±0,86) and 10/21 (1,84±0,13) were statistically different (p = 0,009). Among the groups 20/7 (1,63±0,11) and 20/21 (2,48±0,28) was observed statistically significant difference (p = 0,003). CONCLUSION: The AgNOR technique can be useful in identification of cells changes induced by B[a]P.

p53 and bcl-2 expression and argyrophilic nucleolar organizer regions in patients with malignant maxillary sinus tumours

1997 ◽  
Vol 111 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Torahiko Nakashima ◽  
Tadashi Nakashima ◽  
Muneyuki Masuda ◽  
Sohtaro Komiyama
Keyword(s):  
Maxillary Sinus ◽  
Clinical Course ◽  
Nucleolar Organizer ◽  
Nucleolar Organizer Regions ◽  
Malignant Tumours ◽  
Clinicopathological Findings ◽  
Significant Difference ◽  
The Mean ◽  
Maxillary Tumours ◽  
Argyrophilic Nucleolar Organizer Regions

AbstractTo investigate the relation between the clinicopathological findings, and the survival of patients with malignant tumours of the maxillary sinus, and the tumour's biological parameters, we examined the expression of p53 and bcl-2 and the number of silver-stainable nucleolar organizer regions (AgNORs) in 23 paraffin-embedded specimens from primary tumours. Fifteen of 23 (65 per cent) maxillary tumours expressed p53 and two of 23 (nine per cent) tumours expressed the bcl-2 gene product. The mean number of AgNORs per nucleus was 5.2 ± 2.4. There was no relationship between the expression of p53 or bcl-2 and the patient's clinical course. In contrast, there was a statistically significant difference in the survival of patients with a high (>6) number of AgNORs and patients with a low (<6) number of AgNORs. These data suggest that the number of AgNORs may be useful in evaluating the prognosis of patients with malignant maxillary sinus tumours.

scholarly journals Confidence interval approach for evaluating bias in laboratory methods

1988 ◽  
Vol 10 (3) ◽  
pp. 144-146 ◽  
Author(s):  
K. F. Yee
Keyword(s):  
Confidence Interval ◽  
Statistical Tests ◽  
Laboratory Methods ◽  
Mean Values ◽  
Practical Concern ◽  
Alternative Approach ◽  
Interval Approach ◽  
Significant Difference ◽  
The Mean

A statistically significant difference in mean values between two laboratory quantitation methods is interpreted as a bias. Sometimes such a difference is so minute that it does not constitute any practical concern. An alternative approach is to test statistically whether the two methods are close enough, not for equality. This is to look at the confidence interval of the mean method difference and does not entail any additional statistical tests.

scholarly journals Evaluation of the Results of Arthroscopic Release in Limits of Movement in Knees

2020 ◽  
Author(s):  
Mohammad Reza Sobhan ◽  
Seyed Hossein Saeed Banadaky ◽  
Mohammad Shafiee ◽  
Mohammad Gheisari
Keyword(s):  
Statistical Tests ◽  
Cross Sectional Study ◽  
Knee Score ◽  
Cross Sectional ◽  
Mean Values ◽  
Arthroscopic Release ◽  
Lysholm Knee Score ◽  
Significant Difference ◽  
Before And After ◽  
The Mean

Introduction: Limits of movement in knees is one of the most common complications following trauma and surgery. With early diagnosis and appropriate treatment choices, knee replacement and performance improvement are expected in many patients. However, limits of movement in knees is unpleasant and should be corrected as soon as possible. In this study, we decided to evaluate the results of arthroscopic release in motion limits of knees. Methods: This was a descriptive cross-sectional study.14 patients who referred to the Shahid Sadoughi Hospital of Yazd from 2014 to 2016 and diagnosed with knee limitation (flexion or extension restriction of more than 10 degrees) were selected. Patients were undergone arthroscopic release and followed-up for 6 months. Lysholm knee score, degrees of flexion and extension, and patient satisfaction were evaluated. The results were analyzed by SPSS-18 and statistical tests Paired T-test as well as Spearman correlation. Results: The mean age of the patients was 28.92±10.99 years. The most common type of trauma in the patients was femoral distal fracture (46.7%). The frequency of the patients' satisfaction with arthroscopy was as followed: 50% (7 patients), had moderate satisfaction, 28.6% (4 ones), high satisfaction, and 21.4% (3 ones) had low satisfaction.The mean difference in Lysholm Knee Score, improvement in degree of extension, improvement in degree of flexion and pain score before and after arthroscopy were 26.21±14.11,64.78±26.13,3.57±2.92 and 4.13±1.65,respectively.There was a significant difference between the mean values of these factors before and after arthroscopy. Conclusion: According to the results obtained, we can conclude that arthroscopic release is an effective and low-complication method in motion limits of knees.

scholarly journals Nucleolar Organizer Regions (NORs)

1994 ◽  
Vol 112 (4) ◽  
pp. 642-645
Author(s):  
Albina Messias de Almeida Milani Altemani
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Nucleolar Organizer ◽  
Staining Technique ◽  
Parasitic Infections ◽  
Nucleolar Organizer Regions ◽  
Mean Values ◽  
Significant Difference ◽  
Grade 3

Counts of nucleolar regions (NORs) demonstrated by a silver staining technique in paraffin sections, have been used to distinguish between benign and malignant lesions. AgNORs were studied in 24 biopsies from oral cavity (5 cases of normal oral mucosa, 5 of pseudocarcinomatous hyperplasia and 14 of squamous cell carcinoma, subdivided according to degree of differentiation: 5 grade 1, 5 grade 2 and 4 grade 3) to find whether they were helpful in distinguishing pseudocarcinomatous hyperplasia due to chronic parasitic infections from squamous cell carcinoma. Two methods of counting AgNORs were used: (A) a simpler one which counts nucleolar clusters (AgNU) and satellite AgNORs and the other (B) counting all individual AgNORs, including those within AgNUs. In both methods the lowest mean values were observed for grade 3 carcinoma, while the highest belonged to grade 2 carcinoma. The simpler method (A) was the most useful because AgNU counts showed significant difference when pseudocarcinomatous hyperplasia was compared with grade 1 and 2 carcinomas, which are the most difficult to discriminate from it. However the overlapping of values render the technique of limited use in individual cases.

scholarly journals The relationship of religious attitude with self-control andself-discrepancy in students

2019 ◽  
Vol 21 (3) ◽  
pp. 144-148
Author(s):  
Masoud Nikfarjam ◽  
Elham-Sadat Salehi ◽  
Ali Ahmadi
Keyword(s):  
Pearson Correlation ◽  
Self Control ◽  
Cross Sectional ◽  
Mean Values ◽  
Religious Attitude ◽  
Significant Difference ◽  
The Mean ◽  
Self Discrepancy ◽  
Relationship Of ◽  
The Relationship

Background and Aim: Spiritual attitude is one of the factors affecting mental health of students. The purpose of this study was to determine the relationship of religious attitudes with self-control and self-discrepancy (S-D) in students of Shahrekord University of Medical Sciences (SKUMS) in 2017. Methods: In this cross-sectional study, 328 students of the SKUMS were studied. The participants completed Tangney Self-control Survey, Higgins Self-discrepancy Questionnaire, a religious attitude questionnaire, and a checklist of demographic information. For data analysis, in addition to descriptive statistics, independent t-test, Pearson correlation coefficient, and one-way ANOVA were used. Stata software was used to analyze the data. Results: The mean values of religious attitude, self-control, and self-discrepancy were higher in women in comparison with men (P< 0.05). There was a significant difference between self-control religious beliefs, actual-self minus actual-self (S-D2), and self-discrepancy in terms of total monthly income of all family members (P< 0.05). Academic discipline was significantly associated with religious attitude, ideal-self minus actual-self (S-D1), S-D2, and S-D (P< 0.05), but self-control difference was not significant (P= 0.84). There was a linear relationship, significant correlation of religious attitude with the mean values of self-control, required self, actual-self, idea-self, self-discrepancy, and S-D1 and S-D2 (P< 0.05). Conclusion: According to the results of this study, religious attitude was associated with self-control, self-discrepancy, and their dimensions.

scholarly journals Relationship Between Proximal Articular Set Angle and Hallux Abducto Valgus

2002 ◽  
Vol 92 (6) ◽  
pp. 331-335 ◽  
Author(s):  
Jill Ferrari ◽  
James Malone-Lee
Keyword(s):  
Metatarsal Head ◽  
Valgus Deformity ◽  
Normal Range ◽  
Mean Values ◽  
Lateral Tilt ◽  
Significant Difference ◽  
Positive Linear Correlation ◽  
Males And Females ◽  
The Mean ◽  
The Relationship

A study of radiographs from 50 males and 50 females was undertaken to determine whether a relationship existed between the proximal articular set angle and the hallux abductus angle. Gender differences in the relationship were also investigated. The normal range for the proximal articular set angle was –2.6° to 8.6°, with a mean of 5°. There was no significant difference in the mean values between males and females. A positive linear correlation between the proximal articular set angle and hallux abducto valgus deformity was found (R2 = 0.52), suggesting that an increased lateral tilt of the metatarsal head is one of the factors that lead to hallux abducto valgus deformity. The relationship between proximal articular set angle and hallux abducto valgus deformity was similar in males and females and did not account for the increased hallux deformity seen in females. (J Am Podiatr Med Assoc 92(6): 331-335, 2002)

scholarly journals What is the Relationship among Patients' Position and Intra-abdominal Pressure and Mean Arterial Pressure?

2019 ◽  
pp. 1-8
Author(s):  
Yusef Haghighi Moghaddam ◽  
Elnaz Hosseinnejhad ◽  
Mohammad Amin Valizade Hasanloei ◽  
Javad Rasouli
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Repeated Measures ◽  
Body Position ◽  
Statistical Tests ◽  
Abdominal Pressure ◽  
Abdominal Hypertension ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship

Background: The prevalence of intra-abdominal hypertension in ICU patients is about 50% and can be affected by changing the position of the patients. This study aimed to investigate the relationship between changing patient positions in bed with intra-abdominal pressure and mean arterial pressure among mechanically ventilated patients in ICU. Methods: This study was a clinical trial conducted on 68 patients admitted in intensive care units of Imam Khomeini hospital of Urmia city, Iran. The patients were selected through convenience sampling based on the inclusion criteria. In this study, the effects of changes in five positions (0, 15, 30, 45, left and right lateral position with 30 degrees) on the mean arterial pressure was evaluated. Statistical tests such as chi square and repeated measures ANOVA were used as well. All analyzes were performed using SPSS 21. Results: In this study, there were 24 men (35.3%) and 44 women (64.7%). The mean age, weight and height of patients were 70.35±16.98 years, 75.76±9.77 kg and 168.82±8.14 cm, respectively. There was no significant difference regarding intra-abdominal pressure by gender (p<0.05). There was a significant difference regarding intra-abdominal pressure between first, second, fourth and fifth measurements (p<0.001). There was a significant difference regarding mean arterial pressure between first, second, third, fourth and fifth measurements (p<0.001). Significant differences were observed between the fifth and fourth mean arterial pressure measurements as well (p<0.001). Conclusion: According to the results of this study, the changing of patient's body position from supine to higher positions lead to the increase of intra-abdominal pressure.

A COMPARISON OF TWO METHODS FOR MEASUREMENT OF ALDOSTERONE SECRETION RATE IN MAN

1966 ◽  
Vol 53 (2) ◽  
pp. 177-188 ◽  
Author(s):  
P. Lund-Johansen ◽  
T. Thorsen ◽  
K. F. Støa
Keyword(s):  
Urinary Excretion ◽  
Normal Subjects ◽  
Secretion Rate ◽  
Aldosterone Secretion ◽  
Simple Method ◽  
Mean Values ◽  
Pathological Conditions ◽  
Significant Difference ◽  
Derivative Method ◽  
The Mean

ABSTRACT A comparison has been made between (A), a relatively simple method for the measurement of aldosterone secretion rate, based on paper chromatography and direct densitometry of the aldosterone spot and (B) a more elaborate isotope derivative method. The mean secretion rate in 9 normal subjects was 112 ± 26 μg per 24 hours (method A) and 135 ± 35 μg per 24 hours (method B). The »secretion rate« in one adrenalectomized subject after the intravenous injection of 250 μg of aldosterone was 230 μg per 24 hours (method A) and 294 μg per 24 hours (method B). There was no significant difference in the mean values, and correlation between the two methods was good (r = 0.80). It is concluded that the densitometric method is suitable for clinical purposes as well as research, being more rapid and less expensive than the isotope derivative method. Method A also measures the urinary excretion of the aldosterone 3-oxo-conjugate, which is of interest in many pathological conditions. The densitometric method is obviously the less sensitive and a prerequisite for its use is an aldosterone secretion of 20—30 μg per 24 hours. Lower values are, however, rare in adults.

CONCENTRADO PROTEICO OBTIDO DAS FOLHAS DE MANDIOCA (Manihot esculenta Crantz) DE TRÊS VARIEDADES COMERCIAIS.

2017 ◽  
Vol 13 (1) ◽  
Author(s):  
Izabel Aparecida Soares ◽  
Mauro Sérgio Téo ◽  
Carlise DEBASTIANI ◽  
Suzymeire BARONI ◽  
Vanessa Silva RETUCI
Keyword(s):  
Manihot Esculenta ◽  
Crude Protein ◽  
Hydrocyanic Acid ◽  
Protein Concentrate ◽  
Manihot Esculenta Crantz ◽  
White Variety ◽  
Mean Values ◽  
Randomized Design ◽  
Significant Difference ◽  
The Mean

O trabalho teve por objetivo verificar diferenças entre rendimento do concentrado proteico e proteína bruta da folha da mandioca (Manihot esculenta Crantz), obtidos a partir de três variedades comerciais: branca, cascuda e vermelha. As manivas foram plantadas seguindo o delineamento experimental inteiramente casualizado com três repetições. Nas comparações entre as variedades, considerou coletas escalonadas pós-plantio, realizadas aos 12, 14 e 16 meses. O concentrado proteico foi obtido a partir da farinha das folhas inteiras e submetido ao método de termo - coagulação ácido e a proteína bruta pelo método padrão AOAC. Os dados foram submetidos a análise de variância e comparados pelo teste de Tukey - 5% de probabilidade. Os resultados não indicaram diferença significativa entre as médias obtidas para rendimento de concentrado proteico. Para a variável porcentagem de proteína bruta a variedade Branca foi a que apresentou maior valor, com média de 46,25%, seguida pela Cascuda e Vermelha, 44,52% e 37,30%, sucessivamente. Conclui-se que outros estudos devem avaliar condições que possam influenciar no teor de proteína foliar, como clima e solo, e, avaliar os níveis de ácido cianídrico de cada variedade, indicando qual das três é a melhor para a extração do concentrado proteico das folhas. Palavras chaves: Manihot esculenta Crantz, variedades comerciais, concentrado proteico, proteína bruta. ABSTRACT: The study aimed to assess the differences between income protein concentrate, crude protein of cassava leaf (Manihot esculenta Crantz), obtained from three commercial varieties: white, red and cascuda. The cuttings were planted following the completely randomized design with three replications. Comparisons between the varieties considered after planting staggered collections, held on 12, 14 and 16 months. The protein concentrate was obtained from flour of whole sheets and subjected to the term method - acid coagulation and crude protein by AOAC standard method. The data were submitted to ANOVA and Tukey test - 5% probability. The results indicated no significant difference between the mean values obtained for protein concentrate income. For the variable percentage of crude protein White variety showed the highest, with an average of 46.25%, followed by cascuda and Red, 44.52% and 37.30%, successively. We conclude that further studies should evaluate conditions that may affect the leaf protein content, such as climate and soil, and evaluate the hydrocyanic acid levels of each variety, indicating which of the three is the best for the extraction of protein concentrate from leaves Key words: Manihot esculenta Crantz, commercial varieties, protein concentrate, crude protein.

Rice tablet (Aluminum Phosphide) poisoning

2016 ◽  
Vol 5 (11) ◽  
pp. 5041
Author(s):  
Farkhondeh Jamshidi ◽  
Ahmad Ghorbani ◽  
Sina Darvishi*
Keyword(s):  
Medical Records ◽  
Statistical Tests ◽  
Patient Records ◽  
Demographic Information ◽  
Aluminum Phosphide ◽  
Men And Women ◽  
Significant Difference ◽  
The Mean ◽  
Aluminum Phosphide Poisoning ◽  
Commit Suicide

The abuse of some pesticides especially to suicide is one of the current problems of pesticides. Aluminum phosphide induced poisoning usually happens to suicide and sometimes it is due to accidental occupational exposure and in a few cases it has some criminal intensions. This study is conducted to evaluate patients poisoned with aluminum phosphide. In the present study the medical records of cases of poisoning with rice tablets (aluminum phosphide) hospitalized in Ahvaz Razi hospital is studied. Accordingly, a checklist is prepared that included demographic information of patients (age, gender) and information on patient records (information on poisoning) are completed using the patients’ medical records. The analysis of data is done by SPSS V22. 18 patients poisoned with rice tablet (aluminum phosphide) are studied. Results of the study show that 11 patients are male and seven are female. The mean patient age is 27.06 ±8.04 years that is 28 ±9 and 25 ±6.02 in men and women respectively. Statistical tests show no statistically significant difference in mean age in both genders (P> 0.05). Among patients, 11 subjects took aluminum phosphide to attempt suicide and 3 cases took it unintentionally and of course the reason is not mentioned in four cases. Among the patients who tried to commit suicide by taking aluminum phosphide, 6 cases are male and 5 cases are female that no statistically significant difference is observed between the genders in this respect (P> 0.05). In addition to the study of the complications caused by this poisoning and its mortality, it is recommended to responsible authorities to provide the necessary educations and treatments to prevent this type of poisoning.

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