scholarly journals A quantitative study of the influence of coprocessing of binders on the mechanical properties of paracetamol tablets

2010 ◽  
Vol 46 (2) ◽  
pp. 205-212 ◽  
Author(s):  
Abayomi Tolulope Ogunjimi ◽  
Gbenga Alebiowu
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Experimental Design ◽  
Brittle Fracture ◽  
Factorial Design ◽  
Quantitative Study ◽  
Applied Pressure ◽  
Interaction Effects ◽  
Factorial Experimental Design ◽  
N Concentration

A 2³ factorial experimental design has been used to quantitatively study individual and interaction effects of the nature of binder (N), concentration of binder (C) and the applied pressure (P) on two mechanical properties, namely, tensile strength (TS) and brittle fracture index (BFI), of paracetamol tablets. The factorial design was also used to study the quantitative effects of coprocessing of binders on the mechanical properties. The results obtained from this study suggest that the nature (i.e. plastic/elastic) and ratio of binders coprocessed together alter the influence of C and P on TS and BFI.

Anisotropic Mechanical Properties of Rapid Prototyping Parts Fabricated by Stereolithography

2021 ◽  
Vol 13 (9) ◽  
pp. 1812-1819
Author(s):  
Na-Na Yang ◽  
Hao-Rui Liu ◽  
Ning Mi ◽  
Qi Zhou ◽  
Li-Qun He ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Elastic Modulus ◽  
Brittle Fracture ◽  
Fracture Surface ◽  
Elongation At Break ◽  
Build Orientation ◽  
Range Distribution ◽  
Anisotropic Mechanical Properties ◽  
Orientation Experiment

Stereolithography (SLA)-manufactured parts behave with anisotropic properties due to the varying interface orientations generated by the layer-based manufacturing process. Part build orientation is a very important factor of anisotropic mechanical properties. In this paper, the build orientation experiment was designed to study the anisotropic behaviour of the mechanical properties of the SLA parts based on the orientation relationship between the force and the layer. The results show that there are obvious brittle characteristics on the fracture surface of the specimens and microcracks perpendicular to the direction of the layer distributed on the side of the fracture. The mechanical properties under brittle fracture have different degrees of sensitivity to the build orientation. Among all the build orientations, whether a specimen is built flat or on an edge shows obvious difference in tensile strength, and the relative range distribution reaches 35%. The changes in elastic modulus and the elongation at break are the most obvious in different angles relative to the XY plane, and the relative range distribution reaches 62% and 56% respectively. In all the build orientations designed, the tensile strength is the largest when it is placed on the edge at 0° with Y-axis in the XY plane, the elastic modulus is the largest when it was placed vertically, and the elongation at break is the largest when it is placed flat at 45° with Y-axis in the XY plane.

scholarly journals The importance of factorial design in tissue engineering and biomaterials science: Optimisation of cell seeding efficiency on dermal scaffolds as a case study

2018 ◽  
Vol 9 ◽  
pp. 204173141878169 ◽  
Author(s):  
Alexandra Levin ◽  
Vaibhav Sharma ◽  
Lilian Hook ◽  
Elena García-Gareta
Keyword(s):  
Tissue Engineering ◽  
Experimental Design ◽  
Factorial Design ◽  
Three Dimensional ◽  
Cell Types ◽  
Cell Seeding ◽  
Factorial Experimental Design ◽  
Seeding Efficiency

This article presents a case study to show the usefulness and importance of using factorial design in tissue engineering and biomaterials science. We used a full factorial experimental design (2 × 2 × 2 × 3) to solve a routine query in every biomaterial research project: the optimisation of cell seeding efficiency for pre-clinical in vitro cell studies, the importance of which is often overlooked. In addition, tissue-engineered scaffolds can be cellularised with relevant cell type(s) to form implantable tissue constructs, where the cell seeding method must be reliable and robust. Our results show the complex relationship between cells and scaffolds and suggest that the optimum seeding conditions for each material may be different due to different material properties, and therefore, should be investigated for individual scaffolds. Our factorial experimental design can be easily translated to other cell types and three-dimensional biomaterials, where multiple interacting variables can be thoroughly investigated for better understanding of cell–biomaterial interactions.

scholarly journals Empirical Verification of Youth Socialization on Sexuality in Nigeria

2019 ◽  
pp. 115-119
Author(s):  
Yusuff A. Q. ◽  
Akanbi O. A. ◽  
Adams O. T. ◽  
Aremu Z. O.
Keyword(s):  
Sexual Behavior ◽  
Experimental Design ◽  
Family Background ◽  
Interactive Effect ◽  
Educational Status ◽  
Interaction Effects ◽  
Factorial Experimental Design ◽  
Empirical Verification ◽  
Social Units

A completely factorial experimental design was undertaken to verify and proffer solutions to the effect of socialization on sexuality of Nigerian youths. Though, Man’s interaction with his environment and other systems around him model his character. This research investigated the effect of family background, religion and educational status with all allowances for interactive effect of these social units in modeling the sexual behavior of youths. The interaction effects were not significant. Recommendations were made to correct the menaces’.

scholarly journals The Design of Glass Fiber//Epoxy Composite Pipes by the Implementation of the Full Factorial Experimental Design

2016 ◽  
Vol 12 (3-4) ◽  
Author(s):  
Biljana Pop Metodieva ◽  
Sara Srebrenkoska ◽  
Vineta Srebrenkoska
Keyword(s):  
Tensile Strength ◽  
Experimental Design ◽  
Glass Fiber ◽  
Filament Winding ◽  
Factorial Experimental Design ◽  
The Third ◽  
Fiber Tension ◽  
Full Factorial Experimental Design ◽  
Composite Pipes ◽  
Full Factorial

In the present work, the attempt was made to assess the applicability of the full factorial experimental design in predicting the hoop tensile strength of glass fiber/ epoxy resin composite pipes by using of a split disk specimens. Split disk tension tests, provide reasonably accurate information with regard to the apparent tensile strength of composite pipe.In the study we used a number of composite pipes with different fiber orientation, fiber tension and velocity of the winding. The composite pipes were made by using of filament winding technology includes winding of resin impregnated fibers into a tool and hardening of the wound structure. The preparation of the composite experimental samples was conducted in accordance with the 23 full factorial experimental design. The winding speed of the composites was taken to be the first factor, the second was the fiber tension and the third winding angle. The first factor low and high levels were set at 5,21 m/min and 21 m/min, respec­tively, for the second factor – at 64N and 110N, respectively, and for the third factor – at 100 and 900. To approxi­mate the response i.e. the hoop tensile strength of the composite pipes within the study domain (5,25 – 21) m/min x (64-110)N x (10 – 90)0, the first order linear model with the interaction was used. The influence of each individual factor to the response function was established, as well as the influence of the interaction of the two and three factors. We found out that the estimated first-degree regression equation with the interaction gave a very good approximation of the experimental results of the hoop tensile strength of composites within the study domain.

scholarly journals The Effect of Laser Offset Welding on Microstructure and Mechanical Properties of 301L to TA2 with and without Cu Intermediate Layer

Metals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1138 ◽  
Author(s):  
Xiaohui Zhao ◽  
Zhenfu Shi ◽  
Chao Deng ◽  
Yu Liu ◽  
Xin Li
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Brittle Fracture ◽  
Welded Joints ◽  
Intermediate Layer ◽  
Welded Joint ◽  
Eutectic Reaction ◽  
Dissimilar Materials ◽  
Microstructural Characterization ◽  
The Other

Based on dissimilar materials of 301L/TA2, the effect of laser offset and copper intermediate layer on welded joints was investigated. First, the process optimization of laser offsets indicated that the tensile strength of welded joint without intermediate layer was reached to the highest value when the laser was applied on the TA2 side. On the other hand, the tensile strength of welded joint with intermediate layer performed well when laser was applied in the middle position. Then, microstructural characterization and mechanical properties of welded joints were observed and tested. Based on eutectic reaction and peritectic reaction: TiFe and TiFe2 compounds were produced for welded joint without intermediate layer. Cu-Fe solid solutions and Cu-Ti compounds were generated when copper was used as the intermediate layer. The maximum tensile strength of welded joint with and without copper intermediate layer were 396 and 193 MPa, respectively. Finally, fracture mechanism of 301L/TA2 welded joint was studied: Fe-Ti compounds caused brittle fracture of welded joints without intermediate layer; brittle fracture took place in rich copper and Cu-Ti compounds area of welded joints with copper intermediate layer.

Mechanical Properties and Surface Integrity of Recycling Aluminum 6061 by Hot Extrusion Process

2017 ◽  
Vol 894 ◽  
pp. 21-24 ◽  
Author(s):  
S.Nю Ab Rahim ◽  
Mohd Amri Lajis
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Ultimate Tensile Strength ◽  
Brittle Fracture ◽  
Tensile Test ◽  
Surface Integrity ◽  
Hot Extrusion ◽  
Extrusion Process ◽  
Test Results ◽  
Mechanical And Structural Properties

In the present work, aluminum AA6061 chip metals were extruded by hot extrusion and the effect of extrusion parameters on the mechanical properties and surface integrity were investigated. The objective of the present studies it to analyze the mechanical and structural properties of 6061 after plastic consolidation by hot extrusion. Tensile test results showed that material extruded using temperature 550°C exhibit higher ultimate tensile strength (UTS) compared with temperature of 400°C. Fracture surfaces shown that ductile fracture mode occurred at condition 500°C and 2 hours, and brittle fracture occurred at condition 400°C.

Full Factorial Design Analysis on Mechanical Properties of Electron Beam Irradiated-Flame Retarded LDPE/EVA Composites

2015 ◽  
Vol 786 ◽  
pp. 58-62
Author(s):  
Tiam Ting Tee ◽  
Soo Tueen Bee ◽  
Azman Hassan ◽  
Chantara Thevy Ratnam ◽  
Tin Sin Lee ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Factorial Design ◽  
Design Analysis ◽  
Full Factorial Design ◽  
Elongation At Break ◽  
Flame Retarded ◽  
Irradiation Dosage ◽  
Factorial Design Analysis ◽  
Full Factorial

This study aims to investigate the effect of three factors, namely alumina trihydrate (ATH), montmorillonite (MMT) and irradiation dosage on the mechanical properties (tensile strength and elongation at break) of flame-retarded LDPE-EVA composites. In this study, full factorial design analysis was used to examine the effects of factors and their combination interactions on mechanical properties. ATH is the most significant factor in affecting the tensile strength of LDPE-EVA blends due to the poor compatibility effect between ATH particles and LDPE-EVA matrix. However, MMT is the least significant factor on tensile strength of LDPE-EVA composites. ATH was the most significant in affecting the elongation at break of LDPE-EVA blends. This is because the increasing of ATH amount in LDPE-EVA matrix could restrict the mobolity of polymer chains in LDPE-EVA matrix. However, the factor of irradiation dosage was found to be insignificant in affecting the elongation at break of LDPE-EVA blends.

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