scholarly journals The greenhouse provocation test for determination of resistance to potato common scab [Streptomyces scabiei (ex Thaxter 1982) Lambert and Loria 1989]

2008 ◽  
Vol 53 (No. 2) ◽  
pp. 72-80
Author(s):  
J. Domkářová ◽  
B. Vokál ◽  
V. Horáčková ◽  
J. Brož
Keyword(s):  
Genetic Resources ◽  
High Resistance ◽  
Common Scab ◽  
Evaluation Method ◽  
Rating Scale ◽  
Soil Analysis ◽  
Provocation Test ◽  
Infested Soil ◽  
Provocation Tests ◽  
Resource Collection

Between 2002 and 2004 the evaluation method of resistance to common scab was tested on potato genetic resources. The resistance of potato tubers to common scab was evaluated in the greenhouse provocation tests with planting in naturally infested soil. The test was evaluated on the tubers of 26 varieties and hybrids of <i>Solanum tuberosum</i> derived from a potato genetic resource collection. Ten tubers of each sample were individually planted into three-liter pots containing infested soil. Analysis of variance confirmed significant differences among individual varieties and hybrids as well as among the years. A rating scale for the evaluation of resistance to common scab was designed. The genotypes ranked into scores 7 (high resistance) to 9 (very high resistance); on the new scale they could be considered perspective genetic resources in breeding for improvement of the level of this character. The evaluated set consisted of genotypes: Samantana, Karin, Monika, Impala, Santé, Annabelle, YP 94-067, YP 91-123, BEE J 85, Viola, and Granola.

The Effects of Long-Term Treatment by Immunotherapy and Fluticazone on Broncial Hyperreactivity

2003 ◽  
Vol 1 (1) ◽  
pp. 13-16
Author(s):  
G. Ilonidis ◽  
G. Anogianakis ◽  
Chr. Trakatelli ◽  
A. Anogeianaki ◽  
J. Giavazis ◽  
...  
Keyword(s):  
Provocation Test ◽  
Term Treatment ◽  
Provocation Tests ◽  
Group I ◽  
Long Term Treatment ◽  
Group Ii ◽  
Male Subjects

Thirty subjects (20 female and 10 male), all allergic to the mites D. Pteronyssinus and D. Farinae, participated in the present study which covered a period of four years. The subjects were randomly divided in two groups. Group I included 10 female and 5 male subjects, with an average age of 25.8 (+/− 3.5) years who received immunotherapy only. Group II had an average age of 31.5 (+/− 4) years and they received immunotherapy along with fluticazone propionate (1000mcg/day). The protocol for immunotherapy was the same for both groups. The basis FEV1 was determined for each subject of both Groups I and II and afterwards they were subjected to provocation tests of nebulized methacholine solution administered in consecutively larger concentrations until a drop in FEV1 >20 % (PC20), was observed. Three years later, when their therapy was completed, all subjects were subjected to the same provocation test and a significant reduction in bronchial hyperactivity was documented for both groups. In particular, for Group I, the percentage of change in FEV1 values was 27.25 +/- 5.23 % and PC20 5.11 +/− 2.64 mg/ml before immunotherapy, while after immunotherapy the same indicators were 22.22 +/- 7.08 % (P<0.05) and 6.85 +/− 4.03 mg/ml, (P<0.05) respectively. For Group II, the percentage of change in FEV1 values was 26.28 +/− 2.5 % and PC20 5.42 +/− 2.5 mg/ml before immunotherapy, while after immunotherapy the same indicators were 12.27 +/- 2.49 % (P<0.01)and 11.64 +/− 5.14 mg/ml, P<0.01 respectively. It is concluded that although significant reduction in hyperreactivity can be achieved through immunotherapy, the combination of immunotherapy with daily fluticazone propionate administration shows the most promising results.

Knowledge-Scientific Evaluation of Social Service Systems

2018 ◽  
pp. 120-150
Author(s):  
Yoshiteru Nakamori ◽  
Fei Meng ◽  
Van-Nam Huynh
Keyword(s):  
Education Program ◽  
Social Service ◽  
Evaluation Method ◽  
Rating Scale ◽  
Current Level ◽  
Service Systems ◽  
Worth Living ◽  
Scientific Evaluation ◽  
Scale Method ◽  
New Knowledge

This chapter proposes a new evaluation method for social service systems in order to support participants to create new knowledge and value. The main proposal is a rating scale method that can evaluate the current level (as-is) and the future desire (to-be) of participants, and with which we can analyze achievements of individuals. By using a concrete example of an education program, which is a worth living discovery seminar for retired men, the chapter reports the results of hypothetical tests on the relationships between items of evaluation and an interesting finding related to the reason of differences in attitude of participants.

scholarly journals Nasal Provocation Test with Cat and Dog Extracts: Results according to Molecular Components

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Andres Sánchez ◽  
Ricardo Cardona ◽  
Marlon Munera ◽  
Victor Calvo ◽  
Manuela Tejada-Giraldo ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Clinical Symptoms ◽  
Provocation Test ◽  
Control Group ◽  
Nasal Provocation Test ◽  
Allergen Components ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Increased Risk ◽  
Can F 1

Background. IgE sensitization (atopy) to pets is commonly evaluated using pet dander extracts. However, the diagnosis by components seems to be more adequate to evaluate the clinical relevance (allergy) of sIgE sensitization. Objective. To study the association between IgE sensitization to pet allergen components and clinical symptoms. Methodology. Dander extracts and sIgE levels to pet components (Can f 1, Can f 2, Can f 3, Can f 5, Fel d 1, Fel 2, and Fel 4) were measured in a rhinitis group (n=101) and a control group (n=68). Nasal provocation tests with pet extract were done in patients with atopy to pets. Results. Dog (34.6% vs. 23.5%) and cat dander (26.7% vs. 8.8%, p=0.05) IgE sensitization was frequent among rhinitis and no-rhinitis subjects, and it was similar to dog (29.7% vs. 20.5%) and cat (18.8% vs. 8.8%) components. Polysensitization for dog (3.1, 95% CI: 1.5 to 6.1, p<0.001) or cat (2.5, 95% CI: 0.8 to 8.0, p=0.01) components was the principal risk factor for a positive nasal provocation test. Additionally, positive nasal provocation test with one animal increased the risk of atopy and positive nasal provocation test to others animals. Pet ownership or asthma was not associated with increased risk of atopy or positive nasal provocation test. Conclusions. Sensitization to pet dander extract identifies atopic patients, but its utility to predict clinical relevance is poor. Allergenic components could help to define the clinical relevance of sensitization to furry animals and could reduce the need for provocation test.

scholarly journals Local allergic rhinitis

2014 ◽  
Vol 67 (suppl. 1) ◽  
pp. 49-56
Author(s):  
Maja Buljcik-Cupic ◽  
Dragana Lemez ◽  
Slobodan Savovic ◽  
Ljiljana Jovancevic ◽  
Danijela Dragicevic
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Mucosa ◽  
Immunoglobulin E ◽  
Provocation Test ◽  
Allergic Response ◽  
Prick Test ◽  
Local Allergic Rhinitis ◽  
Provocation Tests ◽  
Number Of Patients ◽  
The Impact

Local allergic rhinitis is a localized allergic response of the nasal mucosa to aeroallergens in the absence of atopy with characteristic production of specific local immunoglobulin E antibodies in the nasal mucosa, T helper type 2 cellular infiltration response during the exposure to aeroallergens and positive results via the nasal allergic provocation test with the release of inflammatory mediators (triptase and eosinophil cationic proteins). Even though the prevalence of local allergic rhinitis has been and is still being investigated, a large number of patients with diagnosed non-allergic rhinitis or idiopathic rhinitis are currently classified as having local allergic rhinitis. The causes of local allergic rhinitis are most commonly house dust, dust mites, pollens and many others. Diagnosis of local allergic rhinitis is made using nasal allergen provocation tests when the prick test for standard inhalation allergens and the serum specific immunoglobulin analysis for aeroallergens are negative. The increasing amount of data on localized allergic response in non-atopic patients asks for many answers regarding local allergic rhinitis. These answers can be obtained by a study on the prevalence and incidence in children and adults, the impact of positive family atopy in the development of disease, the impact of associated diseases of the lower respiratory tract and conjunctiva, the effectiveness of drug treatment and the issue of administration of specific immunotherapy.

Genotyping of Vitis vinifera L. within the Slovak national collection of genetic resources

2014 ◽  
Vol 9 (8) ◽  
pp. 761-767
Author(s):  
Ivana Dokupilová ◽  
Daniele Migliaro ◽  
Daniel Mihálik ◽  
Manna Crespan ◽  
Ján Kraic
Keyword(s):  
Genetic Diversity ◽  
Vitis Vinifera ◽  
Genetic Resources ◽  
Genetic Variants ◽  
Genetic Resource ◽  
Vitis Vinifera L ◽  
Total Genetic Diversity ◽  
Unusual Phenomenon ◽  
Resource Collection

AbstractMicrosatellites were used as a very effective tool for genetic diversity analysis and characterization of 51 grapevine (Vitis vinifera L.) accessions from the national collection of genetic resources. Genetic diversity was relatively high, 8.91 alleles were detected per analysed microsatellite locus in average, and fifty-one accessions were distinguished into 45 groups. Distribution of recent Slovak cultivars across the dendrogram accented both their genetic diversity and the effectiveness of the national breeding program in maintaining genetic diversity and generating new genetic variants. Each cultivar was different from the others and twelve of them contained 77.6% of the total genetic diversity of the whole analysed set. Microsatellite patterns were also able to confirm parentage in selected Slovak cultivars. An unusual phenomenon of triallelism was also detected in one of the analysed accessions. The present study has initiated molecular characterization within the national grapevine genetic resource collection and their comparison with well-established international cultivars.

Targhee: An oblong russet potato variety with attractive tubers and high resistance to common scab

1973 ◽  
Vol 50 (8) ◽  
pp. 293-296 ◽  
Author(s):  
J. J. Pavek ◽  
D. R. Douglas ◽  
H. C. McKay ◽  
R. E. Ohms
Keyword(s):  
Potato Variety ◽  
High Resistance ◽  
Common Scab

Acoustic Rhinometry in the Diagnosis of Occupational Rhinitis

1996 ◽  
Vol 10 (6) ◽  
pp. 393-398 ◽  
Author(s):  
Maija L Hytönen ◽  
Eeva L Sala ◽  
Henrik O Malmberg ◽  
Henrik Nordman
Keyword(s):  
Nasal Cavity ◽  
Provocation Test ◽  
Acoustic Rhinometry ◽  
Cross Sectional ◽  
Occupational Rhinitis ◽  
Limit Value ◽  
Provocation Tests ◽  
Calculated Parameter ◽  
Essential Change ◽  
The Mean

Acoustic rhinometry (ARM) has been used to study the nasal cavity geometry and the response in nasal provocations. However, the use of ARM in the diagnosis of occupational rhinitis (OR) has not been reported. The purpose of this study was to find an ARM parameter and a limit value that could be used in provocation tests to express an objective change in the nasal cavity geometry. We used a new calculated parameter, Volume MCA%, for describing the change in the nasal geometry. Volume MCA% is the mean of the percentile changes of nasal volumes and minimal cross-sectional areas in a provocation test. We recommend a decrease of at least 15% in Volume MCA% for the limit of an essential change in the nasal cavity.

scholarly journals Evaluation of the efficacy of respiratory gymnastics in patients with panic attacks

2017 ◽  
Vol 98 (2) ◽  
pp. 277-281
Author(s):  
E Z Yakupov ◽  
A S Shikov
Keyword(s):  
Rating Scale ◽  
Provocation Test ◽  
Neurological Status ◽  
Panic Attacks ◽  
Hyperventilation Syndrome ◽  
Cardiovascular Parameters ◽  
Situational Anxiety ◽  
Before And After ◽  
Personal Anxiety ◽  
Hamilton Rating Scale

Aim. Study of the efficacy of respiratory gymnastics in the treatment of panic attacks. Methods. The study included 28 patients with the diagnosis of «panic attacks»: 22 females and 6 males. All participants followed the specially developed respiratory gymnastics program twice a day daily for 2 months. In each patient neurological status was checked before and after the study, and cardiovascular parameters (heart rate, blood pressure), respiration rate, severity and frequency of panic attacks were registered. For the evaluation of anxiety Spielberger scale for anxiety was used. The level of depression was assessed according to Hamilton rating scale for depression. For identification of hyperventilation syndrome hyperventilation provocation test was performed and Nijmegen questionnaire was used. Results. After respiratory gymnastics for 2 months the frequency of panic attacks decreased by 66%, the number of symptoms during panic attacks decreased by 50%. Respiratory rate decreased by 18%, Nijmegen questionnaire score - by 28%. The level of situational anxiety and depression decreased by 15 and 14%, respectively, and degree of personal anxiety decreased by 5%. Cardiovascular parameters decreased nonsignificantly: pulse - by 3%, systolic and diastolic BP - by 1 and 2%, respectively. Conclusion. Respiratory gymnastics effectively decreases the frequency and severity of panic attacks and can be effectively used in the complex treatment of panic attacks as a safe and effective non-drug method of treatment.

Comparison of Sodium Lactate Infusion and Carbon Dioxide Inhalation Panic Provocation Tests: A Meta-analysis

2021 ◽  
Author(s):  
Umit Tural ◽  
Dan V. Iosifescu
Keyword(s):  
Carbon Dioxide ◽  
Meta Analysis ◽  
Provocation Test ◽  
Sodium Lactate ◽  
Panic Attacks ◽  
Provocation Tests ◽  
Inhalation Challenge ◽  
Carbon Dioxide Co2 ◽  
Lactate Infusion ◽  
The Brain

Abstract Background Sodium lactate (NaL) infusion and carbon dioxide (CO2) inhalation are proven to provoke acute panic attacks (PAs) in patients with panic disorder (PD). A systematic literature search and meta-analysis were performed to compare the effect sizes of these methods. Methods Odds ratios were calculated for each of the original studies and were pooled using the random-effects model. Results Either NaL or CO2 provocations significantly increased the rates of PAs in individuals with PD compared to those in healthy controls. However, the effect size of NaL infusion (OR=25.13, 95% CI=15.48–40.80) was significantly greater than that of CO2 inhalation (OR=10.58, 95%CI=7.88–14.21). Conclusion The evidence for the efficacy of the two panic provocation tests is very strong. Yet, the results support the superiority of NaL infusion over CO2 inhalation challenge as a panic provocation test. Thus, lactate seems a much stronger stimulus than CO2 for the brain suffocation detector.

Negative predictive value of provocation tests for nonsteroidal anti-inflammatory drugs in children

2020 ◽  
Vol 41 (4) ◽  
pp. 285-289 ◽  
Author(s):  
Ozge Yilmaz Topal ◽  
Kulhas C. Ilknur ◽  
Yagmur T. Irem ◽  
Toyran Muge ◽  
Civelek Ersoy ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Provocation Test ◽  
Allergy Clinic ◽  
Predictive Values ◽  
Pediatric Allergy ◽  
Provocation Tests ◽  
Drug Classes ◽  
Drug Provocation Test ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Background: After antibiotics, nonsteroidal anti-inflammatory drugs (NSAID) are one of the leading drug classes responsible for hypersensitivity reactions in children. The drug provocation test (DPT) is the criterion standard for diagnosis. Objective: The aim of the present study was to determine the negative predictive values (NPV) of DPTs with NSAIDs in pediatric patients and to evaluate their attitudes toward NSAID use after a negative DPT result. Methods: The study included all patients who had undergone DPTs between January 1, 2014, and December 31, 2018, in our pediatric allergy clinic for suspected NSAID hypersensitivity reaction and who had a negative result for the suspected agent. Those patients who could be contacted were asked whether the patient had used the same drug again since the DPT and, if so, whether he or she had a reaction. Patients who were reported to have had a reaction were invited to the clinic for reevaluation. Based on the findings from this retesting, the NPVs of the DPTs with NSAIDs were calculated. Results: During the 5-year study period, DPT results were negative for 230 suspected agents in 215 patients. Of these, 143 patients (66.5%) were able to be contacted. A total of 108 patients (75.5%) had used the tested NSAIDs at least once after the provocation test, and five patients (4.6%) reported a reaction on reexposure. Four of these patients declined reevaluation, one patient exhibited no reaction in a second DPT. Therefore, the NPV was calculated as 96.3% (94.3% for ibuprofen, and 100% for paracetamol). Conclusion: The NPVs of DPTs with NSAIDs, especially of paracetamol DPT, is high in children. This finding should reassure the parents of patients who may require NSAID therapy again.

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