Eagle Hemp CBD Gummies Get 50% Off Today v1

2022 ◽  
Author(s):  
Eagle Hemp CBD gummies
Keyword(s):  
Anxiety Disorders ◽  
Anxiety Symptoms ◽  
Analytical Studies

A review published in Neurotherapeutics tested almost 49 Preclinical and analytical studies that found effects of CBD on anxiety symptoms. It found that CBD has “essential potential” to combat anxiety disorders.

Maternal immune and affiliative biomarkers and sensitive parenting mediate the effects of chronic early trauma on child anxiety

2017 ◽  
Vol 48 (6) ◽  
pp. 1020-1033 ◽  
Author(s):  
A. Ulmer-Yaniv ◽  
A. Djalovski ◽  
K. Yirmiya ◽  
G. Halevi ◽  
O. Zagoory-Sharon ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Chronic Stress ◽  
Animal Studies ◽  
Stress Reactivity ◽  
Child Anxiety ◽  
Anxiety Symptoms ◽  
Analysis Model ◽  
Post Traumatic Stress ◽  
And Behavior ◽  
Early Trauma

BackgroundChronic early trauma alters children's stress reactivity and increases the prevalence of anxiety disorders; yet the neuroendocrine and immune mechanisms underpinning this effect are not fully clear. Animal studies indicate that the mother's physiology and behavior mediate offspring stress in a system-specific manner, but few studies tested this external-regulatory maternal role in human children exposed to chronic stress.MethodsWe followed a unique cohort of children exposed to continuous wartime trauma (N= 177; exposed;N= 101, controls;N= 76). At 10 years, maternal and child's salivary immunoglobulin A (s-IgA) and oxytocin (OT), biomarkers of the immune and affiliation systems, were assayed, maternal and child relational behaviors observed, mother and child underwent psychiatric diagnosis, and child anxiety symptoms assessed.ResultsWar-exposed mothers had higher s-IgA, lower OT, more anxiety symptoms, and their parenting was characterized by reduced sensitivity. Exposed children showed higher s-IgA, more anxiety disorders and post traumatic stress disorder, and more anxiety symptoms. Path analysis model defined three pathways by which maternal physiology and behavior impacted child anxiety; (a) increasing maternal s-IgA, which led to increased child s-IgA, augmenting child anxiety; (b) reducing maternal OT, which linked with diminished child OT and social repertoire; and (c) increasing maternal anxiety, which directly impacted child anxiety.ConclusionsOur findings, the first to measure immune and affiliation biomarkers in mothers and children, detail their unique and joint effects on children's anxiety in response to stress; highlight the relations between chronic stress, immune activation, and anxiety in children; and describe how processes of biobehavioral synchrony shape children's long-term adaptation.

Anxiety in cardiology. The use of pregabalin in the treatment of anxiety disorders in patients with cardiovascular diseases

2021 ◽  
Vol 14 (4) ◽  
pp. 428-432
Author(s):  
Anna Antosik-Wójcińska
Keyword(s):  
Cardiovascular Diseases ◽  
Early Diagnosis ◽  
Anxiety Disorders ◽  
Pharmacological Treatment ◽  
Anxiety Symptoms ◽  
Health Consequences ◽  
Cardiovascular Patients ◽  
Starting Point ◽  
Patient Prognosis ◽  
High Level

The paper discusses two issues: the multidirectional relationship between the occurrence of anxiety symptoms and cardiovascular diseases, and the influence of the persistently high level of anxiety on the course of cardiological diseases and patient prognosis. In the discussion on the negative health consequences of anxiety disorders, there is emphasized importance of early diagnosis of these disorders and implementation of its treatment. As a starting point there were presented clinical cases of cardiovascular patients in whom developed anxiety disorders. The following sections discuss various aspects of the pharmacological treatment of anxiety disorders, focusing on the possible use of pregabalin in this.

scholarly journals Parental Involvement in CBT for Anxiety-Disordered Youth Revisited: Family CBT Outperforms Child CBT in the Long Term for Children With Comorbid ADHD Symptoms

2015 ◽  
Vol 22 (5) ◽  
pp. 506-514 ◽  
Author(s):  
Marija Maric ◽  
Francisca J. A. van Steensel ◽  
Susan M. Bögels
Keyword(s):  
Anxiety Disorders ◽  
Emotional Disorders ◽  
Child Behavior Checklist ◽  
Behavioral Therapy ◽  
Attention Problems ◽  
Anxiety Symptoms ◽  
Clinical Severity ◽  
Adhd Symptoms ◽  
Comorbid Adhd

Objective: The objective of this study was to examine the efficacy of child cognitive-behavioral therapy (CCBT) versus family CBT (FCBT) in anxiety-disordered youth with high and low comorbid ADHD symptoms. Method: Youth with anxiety disorders ( n = 123, aged 8-18) were classified in four groups according to (a) the type of CBT received (child vs. family) and (b) their comorbid ADHD symptoms, measured with the Child Behavior Checklist (CBCL) Attention Problems syndrome scale level (normal vs. [sub]clinical). Severity of anxiety disorders was assessed with Anxiety Disorders Interview Schedule–Child and Parent (ADIS-C/P) version and anxiety symptoms via a 71-item anxiety symptom questionnaire, the Screen for Child Anxiety and Related Emotional Disorders (SCARED-71), before and after CBT, and at 3 months and 1-year follow-ups. Results: Based on the severity of anxiety disorders, children with high ADHD symptoms profit more from FCBT than CCBT in the long term. For children low on ADHD symptoms, and for anxiety symptoms and attention problems, no differences between CCBT and FCBT occurred. Conclusion: Family involvement seems a valuable addition to CBT for children with comorbid anxiety and ADHD symptoms.

scholarly journals Evaluation of the Clinical Global Impression Scale among individuals with social anxiety disorder

2003 ◽  
Vol 33 (4) ◽  
pp. 611-622 ◽  
Author(s):  
T. I. ZAIDER ◽  
R. G. HEIMBERG ◽  
D. M. FRESCO ◽  
F. R. SCHNEIER ◽  
M. R. LIEBOWITZ
Keyword(s):  
Anxiety Disorder ◽  
Social Anxiety ◽  
Anxiety Disorders ◽  
Social Anxiety Disorder ◽  
Clinical Global Impression ◽  
Severity Of Illness ◽  
Anxiety Symptoms ◽  
Self Report ◽  
Clinical Global Impression Scale ◽  
Additional Variance

Background. The clinical Global Impression Scale (CGI) is commonly used as a primary outcome measure in studies evaluating the efficacy of treatments for anxiety disorders. The current study evaluated the psychometric properties and predictors of clinicians' ratings on an adapted version of the CGI among individuals with social anxiety disorders.Method. An independent assessor administered the CGI Severity of Illness and Improvement ratings to 123 patients at baseline and the subset of treated patients again mid- and post-treatment.Results. Improvement ratings were strongly related to both concurrent Severity of Illness and changes in Severity of Illness ratings from baseline. Additionally, both CGI ratings were positively correlated with both self-report and clinician-administered measures of social anxiety, depression, impairment and quality of life. Measures of social anxiety symptoms accounted for a large portion of the variance in Severity of Illness ratings, with significant additional variance accounted for by measures of impairment and depression. Changes in social anxiety symptoms from baseline accounted for significant variance in Improvement ratings, but no significant additional variance was accounted for by changes in impairment and depressive symptoms.Conclusions. Our findings support the utility of the CGI as an index of global severity and symptom-specific improvement among individuals with social anxiety disorder.

scholarly journals The impact of stress on financial decision-making varies as a function of depression and anxiety symptoms

2014 ◽  
Author(s):  
Oliver J Robinson ◽  
Rebecca Bond ◽  
Jonathan P Roiser
Keyword(s):  
Decision Making ◽  
Anxiety Disorders ◽  
Trait Anxiety ◽  
Anxiety Symptoms ◽  
Financial Decision Making ◽  
Individual Vulnerability ◽  
Mood And Anxiety Disorders ◽  
Financial Decision ◽  
The Impact ◽  
Selection Of

Stress can precipitate the onset of mood and anxiety disorders. This may occur, at least in part, via a modulatory effect of stress on decision-making. Some individuals are, however, more resilient to the effects of stress than others. The mechanisms underlying such vulnerability differences are nevertheless unknown. In this study we attempted to begin quantifying individual differences in vulnerability by exploring the effect of experimentally induced stress on decision-making. Threat of unpredictable shock was used to induce stress in healthy volunteers (N=47) using a within-subjects, within-session design, and its impact on a financial decision-making task (the Iowa Gambling Task) was assessed alongside anxious and depressive symptomatology. As expected, participants learned to select advantageous decks and avoid disadvantageous decks. Importantly, we found that stress provoked a pattern of harm-avoidant behaviour (decreased selection of disadvantageous decks) in individuals with low levels of trait anxiety. By contrast, individuals with high trait anxiety demonstrated the opposite pattern: stress-induced risk-seeking (increased selection of disadvantageous decks). These contrasting influences of stress depending on mood and anxiety symptoms might provide insight into vulnerability to common mental illness. In particular, we speculate that those who adopt a more harm-avoidant strategy may be better able to regulate their exposure to further environmental stress, reducing their susceptibility to mood and anxiety disorders. The threat of shock paradigm we employed might therefore hold promise as a ‘stress-test’ for determining individual vulnerability to mood and anxiety disorders.

scholarly journals Back-translating a rodent measure of negative bias into humans: the impact of induced anxiety and unmedicated mood and anxiety disorders

2017 ◽  
Author(s):  
Jessica Aylward ◽  
Claire Hales ◽  
Emma Robinson ◽  
Oliver J Robinson
Keyword(s):  
Reaction Time ◽  
Anxiety Disorders ◽  
Computational Model ◽  
Treatment Options ◽  
Reaction Times ◽  
Current Treatment ◽  
Anxiety Symptoms ◽  
Mood And Anxiety Disorders ◽  
Affective Bias ◽  
The Impact

AbstractBackgroundMood and anxiety disorders are ubiquitous but current treatment options are ineffective for large numbers of sufferers. Moreover, recent years have seen a number of promising pre-clinical interventions fail to translate into clinical efficacy in humans. Improved treatments are unlikely without better animal-human translational pipelines. Here, we directly adapt–i.e. back-translate - a rodent measure of negative affective bias into humans, and explore its relationship with a)pathological mood and anxiety symptoms (study one) and b)transient induced anxiety (study two).MethodParticipants who met criteria for mood or anxiety disorder symptomatology according to a face-to-face neuropsychiatric interview were included in the symptomatic group. N = 77(47 asymptomatic; Female = 21; 30 symptomatic; Female = 25) participants completed study one and N = 47 asymptomatic participants (25 female) completed study two. Outcome measures were choice ratios, reaction times and parameters recovered from a computational model of reaction time; the drift diffusion model (DDM).ResultsSymptomatic individuals demonstrated increased negative affective bias relative to asymptomatic individuals (proportion high reward = 0.42(SD = 0.14), and 0.53(SD = 0.17), respectively) as well as reduced DDM drift rate (p = 0.004). No significant effects were observed for the within-subjects anxiety-induction in study 2.ConclusionHumans with pathological anxiety symptoms directly mimic rodents undergoing anxiogenic manipulation. The lack of sensitivity to transient anxiety suggests the paradigm may, moreover, be primarily sensitive to clinically relevant symptoms. Our results establish a direct translational pipeline (and candidate therapeutics screen) from negative affective bias in rodents to pathological mood and anxiety symptoms in humans, and link it to a computational model of reaction time.

scholarly journals The development of an ultra-short, maternal mental health screening tool in South Africa

2019 ◽  
Vol 6 ◽  
Author(s):  
T. van Heyningen ◽  
L. Myer ◽  
M. Tomlinson ◽  
S. Field ◽  
S. Honikman
Keyword(s):  
Mental Health ◽  
South Africa ◽  
Logistic Regression ◽  
Suicidal Ideation ◽  
Anxiety Disorders ◽  
Depressed Mood ◽  
Roc Analysis ◽  
Screening Tool ◽  
Anxiety Symptoms ◽  
Multiple Logistic Regression

Purpose. The burden of common perinatal mental disorders (CPMD) in low-and-middle-income countries is substantially higher than high-income countries, with low levels of detection, service provision and treatment in resource-constrained settings. We describe the development of an ultra-short screening tool to detect antenatal depression, anxiety disorders and maternal suicidal ideation. Methods. A sample of 376 women was recruited at a primary-level obstetric clinic. Five depression and anxiety symptom-screening questionnaires, demographics and psychosocial risk questionnaires were administered. All participants were assessed with the Mini-International Neuropsychiatric Interview (MINI), a structured, diagnostic interview. Screening tool items were analysed against diagnostic data using multiple logistic regression and receiver operating curve (ROC) analysis. Results. The prevalence of MINI-defined major depressive episode (MDE) and/or anxiety disorders was 33%. Overall, 18% of participants expressed suicidal ideation and behaviour, 54% of these had no depression or anxiety diagnosis. Multiple logistic regression identified four screening items that were independently predictive of MDE and anxiety disorders, investigating depressed mood, anhedonia, anxiety symptoms and suicidal ideation. ROC analysis of these combined items yielded an area under the curve of 0.83 (95% CI 0.78–0.88). A cut-off score of 2 or more offered a sensitivity of 78% and specificity of 82%. Conclusion. This novel screening tool is the first measure of CPMD developed in South Africa to include depressed mood, anxiety symptoms and suicidal ideation. While the tool requires further investigation, it may be useful for the early identification of mental health symptoms and morbidity in the perinatal period.

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