Automation and Management of Design Process of the Main Drive for an Innovative Fruits and Vegetables Washer

2021 ◽  
Vol 27 (1) ◽  
pp. 9-17
Author(s):  
V. P. Bui ◽  
◽  
S. S. Gavruishin ◽  
V. B. Phung ◽  
H. M. Dang ◽  
...  
Keyword(s):  
Design Process ◽  
Rational Design ◽  
Fruits And Vegetables ◽  
Rational Solution ◽  
Quality Criteria ◽  
Pareto Optimal ◽  
Optimal Domain ◽  
Wide Range ◽  
A New Technique ◽  
New Generation

A new technique is described, used by the authors to automate the design process of the main drive of a new generation machine intended for industrial washing of fruits and vegetables. To solve the problem of multi-criteria design, the original approach is proposed that uses interconnected mathematical models describing the dynamic behavior, strength reliability and functional characteristics of the machine in a unified information space. The generalized mathematical model includes 12 controlled parameters, 16 functional constraints, and 3 quality criteria. A genetic algorithm was used to find the space of Pareto-optimal solutions. The situational approach was used to select the final rational solution from a set of solutions belonging to the Pareto-optimal domain. The rational design of option the washer found using the proposed approach is compared with the existing ones. The proposed design methodology can be recommended for the design of a wide range of similar mechanical structures.

The Application of Virtual Reality Technology in Teaching of Industrial Design − Outline of the Project for the Human-Computer Interactive Simulation of the Upper Limb Operations

2013 ◽  
Vol 464 ◽  
pp. 420-423 ◽  
Author(s):  
Gui Ping Nie ◽  
Guang Jie Ren
Keyword(s):  
Virtual Reality ◽  
Motion Analysis ◽  
Design Process ◽  
Upper Limb ◽  
Rational Design ◽  
Product Platform ◽  
Interactive Simulation ◽  
Virtual Reality Technology ◽  
Technology In Teaching ◽  
Wide Range

The virtual reality technology can help us to make more scientific and rational design, process more simple and optimized, and teaching more vivid and natural. This text, taking the human-computer interactive simulation of the upper limb operations for example, classifies a wide range of man-machine interfaces that related to the upper limb operations of human, and through the operations analysis and motion analysis of human to find a breakthrough point, so as to carry out the research of targeted countermeasures. The purpose of the research is to complete product platform to provide effective services for teaching and industry.

scholarly journals The Impact of Initial Conditions in N-Body Simulations of Debris Discs

2015 ◽  
Vol 32 ◽  
Author(s):  
E. Thilliez ◽  
S. T. Maddison
Keyword(s):  
Numerical Simulations ◽  
Initial Conditions ◽  
Parent Body ◽  
Dust Trapping ◽  
Physical Context ◽  
Disc Width ◽  
Wide Range ◽  
Belt Width ◽  
New Generation ◽  
The Impact

AbstractNumerical simulations are a crucial tool to understand the relationship between debris discs and planetary companions. As debris disc observations are now reaching unprecedented levels of precision over a wide range of wavelengths, an appropriate level of accuracy and consistency is required in numerical simulations to confidently interpret this new generation of observations. However, simulations throughout the literature have been conducted with various initial conditions often with little or no justification. In this paper, we aim to study the dependence on the initial conditions of N-body simulations modelling the interaction between a massive and eccentric planet on an exterior debris disc. To achieve this, we first classify three broad approaches used in the literature and provide some physical context for when each category should be used. We then run a series of N-body simulations, that include radiation forces acting on small grains, with varying initial conditions across the three categories. We test the influence of the initial parent body belt width, eccentricity, and alignment with the planet on the resulting debris disc structure and compare the final peak emission location, disc width and offset of synthetic disc images produced with a radiative transfer code. We also track the evolution of the forced eccentricity of the dust grains induced by the planet, as well as resonance dust trapping. We find that an initially broad parent body belt always results in a broader debris disc than an initially narrow parent body belt. While simulations with a parent body belt with low initial eccentricity (e ~ 0) and high initial eccentricity (0 < e < 0.3) resulted in similar broad discs, we find that purely secular forced initial conditions, where the initial disc eccentricity is set to the forced value and the disc is aligned with the planet, always result in a narrower disc. We conclude that broad debris discs can be modelled by using either a dynamically cold or dynamically warm parent belt, while in contrast eccentric narrow debris rings are reproduced using a secularly forced parent body belt.

scholarly journals Review of Functional Treatments for Modified Wood

Coatings ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 327
Author(s):  
Morwenna J. Spear ◽  
Simon F. Curling ◽  
Athanasios Dimitriou ◽  
Graham A. Ormondroyd
Keyword(s):  
High Performance ◽  
Responsive Materials ◽  
Wood Modification ◽  
Wide Range ◽  
Natural Wood ◽  
Impregnation Modification ◽  
New Applications ◽  
New Generation ◽  
Dimensional Instability ◽  
Modified Wood

Wood modification is now widely recognized as offering enhanced properties of wood and overcoming issues such as dimensional instability and biodegradability which affect natural wood. Typical wood modification systems use chemical modification, impregnation modification or thermal modification, and these vary in the properties achieved. As control and understanding of the wood modification systems has progressed, further opportunities have arisen to add extra functionalities to the modified wood. These include UV stabilisation, fire retardancy, or enhanced suitability for paints and coatings. Thus, wood may become a multi-functional material through a series of modifications, treatments or reactions, to create a high-performance material with previously impossible properties. In this paper we review systems that combine the well-established wood modification procedures with secondary techniques or modifications to deliver emerging technologies with multi-functionality. The new applications targeted using this additional functionality are diverse and range from increased electrical conductivity, creation of sensors or responsive materials, improvement of wellbeing in the built environment, and enhanced fire and flame protection. We identified two parallel and connected themes: (1) the functionalisation of modified timber and (2) the modification of timber to provide (multi)-functionality. A wide range of nanotechnology concepts have been harnessed by this new generation of wood modifications and wood treatments. As this field is rapidly expanding, we also include within the review trends from current research in order to gauge the state of the art, and likely direction of travel of the industry.

scholarly journals Spatiotemporal Visualization of Insecticides and Fungicides within Fruits and Vegetables Using Gold Nanoparticle-Immersed Paper Imprinting Mass Spectrometry Imaging

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1327
Author(s):  
Run Qin ◽  
Ping Li ◽  
Mingyi Du ◽  
Lianlian Ma ◽  
Yudi Huang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Food Safety ◽  
Gold Nanoparticle ◽  
Pesticide Residue ◽  
Rational Design ◽  
Mass Spectrometry Imaging ◽  
Fruits And Vegetables ◽  
Detection Methods ◽  
Safety Issues ◽  
Spatiotemporal Visualization

Food safety issues caused by pesticide residue have exerted far-reaching impacts on human daily life, yet the available detection methods normally focus on surface residue rather than pesticide penetration to the internal area of foods. Herein, we demonstrated gold nanoparticle (AuNP)-immersed paper imprinting mass spectrometry imaging (MSI) for monitoring pesticide migration behaviors in various fruits and vegetables (i.e., apple, cucumber, pepper, plum, carrot, and strawberry). By manually stamping food tissues onto AuNP-immersed paper, this method affords the spatiotemporal visualization of insecticides and fungicides within fruits and vegetables, avoiding tedious and time-consuming sample preparation. Using the established MSI platform, we can track the migration of insecticides and fungicides into the inner region of foods. The results revealed that both the octanol-water partition coefficient of pesticides and water content of garden stuffs could influence the discrepancy in the migration speed of pesticides into food kernels. Taken together, this nanopaper imprinting MSI is poised to be a powerful tool because of its simplicity, rapidity, and easy operation, offering the potential to facilitate further applications in food analysis. Moreover, new perspectives are given to provide guidelines for the rational design of novel pesticide candidates, reducing the risk of food safety issues caused by pesticide residue.

scholarly journals Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Peter D. Leitner ◽  
Ilja Vietor ◽  
Lukas A. Huber ◽  
Taras Valovka
Keyword(s):  
Dna Binding ◽  
Rational Design ◽  
Dissociation Constants ◽  
Inflammatory Diseases ◽  
Dimethyl Fumarate ◽  
Bioinformatic Analysis ◽  
Quantitative Detection ◽  
Regulatory Sequences ◽  
Wide Range ◽  
Inhibitory Drug

AbstractThe nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore, effective high-throughput methods for the detection of NF-κB DNA binding are essential for studying its transcriptional activity and for inhibitory drug screening. We describe here a novel fluorescence-based assay for quantitative detection of κB consensus double-stranded (ds) DNA binding by measuring the thermal stability of the NF-κB proteins. Specifically, DNA binding proficient NF-κB probes, consisting of the N-terminal p65/RelA (aa 1–306) and p50 (aa 1–367) regions, were designed using bioinformatic analysis of protein hydrophobicity, folding and sequence similarities. By measuring the SYPRO Orange fluorescence during thermal denaturation of the probes, we detected and quantified a shift in the melting temperatures (ΔTm) of p65/RelA and p50 produced by the dsDNA binding. The increase in Tm was proportional to the concentration of dsDNA with apparent dissociation constants (KD) of 2.228 × 10–6 M and 0.794 × 10–6 M, respectively. The use of withaferin A (WFA), dimethyl fumarate (DMF) and p-xyleneselenocyanate (p-XSC) verified the suitability of this assay for measuring dose-dependent antagonistic effects on DNA binding. In addition, the assay can be used to analyse the direct binding of inhibitors and their effects on structural stability of the protein probe. This may facilitate the identification and rational design of new drug candidates interfering with NF-κB functions.

scholarly journals Pulsed Electromagnetic Cross-Well Exploration for Monitoring Permafrost and Examining the Processes of Its Geocryological Changes

Geosciences ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 60
Author(s):  
Viacheslav Glinskikh ◽  
Oleg Nechaev ◽  
Igor Mikhaylov ◽  
Kirill Danilovskiy ◽  
Vladimir Olenchenko
Keyword(s):  
High Performance ◽  
Geophysical Methods ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Data Interpretation ◽  
Industrial Facilities ◽  
Wide Range ◽  
Vector Finite Element ◽  
A New Technique ◽  
Pulsed Electromagnetic

This paper is dedicated to the topical problem of examining permafrost’s state and the processes of its geocryological changes by means of geophysical methods. To monitor the cryolithozone, we proposed and scientifically substantiated a new technique of pulsed electromagnetic cross-well sounding. Based on the vector finite-element method, we created a mathematical model of the cross-well sounding process with a pulsed source in a three-dimensional spatially heterogeneous medium. A high-performance parallel computing algorithm was developed and verified. Through realistic geoelectric models of permafrost with a talik under a highway, constructed following the results of electrotomography field data interpretation, we numerically simulated the pulsed sounding on the computing resources of the Siberian Supercomputer Center of SB RAS. The simulation results suggest the proposed system of pulsed electromagnetic cross-well monitoring to be characterized by a high sensitivity to the presence and dimensions of the talik. The devised approach can be oriented to addressing a wide range of issues related to monitoring permafrost rocks under civil and industrial facilities, buildings, and constructions.

Host-vector systems

1989 ◽  
Vol 324 (1224) ◽  
pp. 477-485 ◽  
Keyword(s):  
Genetic Manipulation ◽  
Pharmaceutical Products ◽  
Host Cells ◽  
Animal Cells ◽  
Vector Systems ◽  
Wide Range ◽  
Novel Host ◽  
Basic Concepts ◽  
Foreign Genes ◽  
New Generation

In 1980 it was only possible to express foreign genes in bacteria and a few easily cultured animal cells. During the subsequent eight years specialized vectors have been developed to allow the genetic manipulation of a wide range of both prokaryotes and eukaryotes. One of the major goals of biotechnology in 1980 was to use host cells as ‘factories’ for the production of proteins that were only available in minute quantities from natural sources. This has already lead to a new generation of pharmaceutical products. Advances in our understanding of host-vector systems have defined new goals. The basic concepts of expression vector design will be illustrated. Some of the new goals are discussed with particular reference to the exploitation of novel host-vector systems to develop vaccines and anti-viral agents against AIDS.

Experiences with alluvial foundations for earth dams in the Prairie provinces

1979 ◽  
Vol 16 (2) ◽  
pp. 255-271 ◽  
Author(s):  
N. Peters ◽  
K. N. Lamb
Keyword(s):  
Rational Design ◽  
Preliminary Design ◽  
Empirical Relationships ◽  
Design Concepts ◽  
Theoretical Design ◽  
Pore Pressures ◽  
Wide Range ◽  
Thick Layers ◽  
Limited Testing ◽  
Prairie Provinces

The foundations for numerous dams in proglacial and interglacial valleys in the Prairie provinces consist of soft alluvial soils. The deposits are up to 60 m deep, and contain thick layers of clay interspersed with lenses and layers of silt, sand, and gravel.This paper describes the damsite investigation and laboratory testing required, the design methods and construction procedures used, and the foundation performance observed during and after construction. A number of empirical relationships between index tests and physical properties of the soils, which provide useful guidelines for preliminary design, are presented.The design approach has gradually evolved from an empirical design with limited testing to a more rational design based on detailed investigations and thorough instrumentation. Increased reliance is placed on observational apparatus to monitor movements and pore pressures to confirm design assumptions as construction proceeds. The theoretical design is always checked with former designs of dams that have performed satisfactorily.Safe economical dams have been constructed in spite of large deformations and high pore pressures. Two case histories illustrate the wide range in dam design for alluvial foundations. The first shows an older design cross section with modifications required to ensure a stable dam, and the second describes a recently constructed dam that incorporates many of the latest design concepts.

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