scholarly journals Chondroitin sodium sulfate – impurities and standardization problems (literature review)

2019 ◽  
Vol 18 (1) ◽  
pp. 25-36
Author(s):  
Е. L. Komarova ◽  
S. V. Chernova ◽  
K. V. Kasumova ◽  
M. S. Tabachnaya ◽  
L. V. Оvsyannikova ◽  
...  

Modern research in the field of chondroitin sulfate chemical composition is considered. Clinical efficiency and safety are shown to depend on the nature and quality of the raw material used, ways of its technological processing and the degree of purification. The composition of chemical compounds (CC) variable is stated to represent the mixture of 2 main isomeric forms: chondroitin 4-sulfate and chondroitin 6-sulfate. In the animal tissue chondroitin 4-sulfate dominates, the content of which is 70 %; the content of chondroitin 6-sulfate is 30 %. The cartilages of sharks and other hydrobionts have got low content of chondroitin 4-sulfate (10 %) and chondroitin 6-sulfate 80 %. Complex polymeric structure and instability of CC composition make the problem of drug standardization on its basis complicated. The impurities encountered in substances are considered. The impurities are divided into several groups: related impurities, technological or mechanical ones uncharacteristic of CC. Comparative analysis of requirements for raw material from the point of view of normative documentation of different countries is carried out and their considerable difference is detected. It has been shown that for raising pharmacological activity the producer of drugs must take into account all the parameters of CC including the structural composition, molecular weight and presence of impurities.

2019 ◽  
Vol 107 ◽  
pp. 72-79
Author(s):  
MAREK WIERUSZEWSKI ◽  
RADOSŁAW MIRSKI ◽  
JAKUB KAWALERCZYK ◽  
ADRIAN TROCIŃSKI

Wood processing plants in Poland are recipients of more than 50% of round wood, which is delivered by the State Forests National Forest Holding. Thus playing a crucial role in the technological processing of raw material for all other wood industry branches. Each group of recipients has individual needs and expectations concerning the quality of the raw material such as, its type and the size of the cross-sections of the assortment used for further production. Therefore, it is economically justified for small production plants to abandon the production of narrow groups of assortments, which usually meets the standards of timber for general purposes. The aim is to make wood processing more flexible and lower the quality of raw material to produce assortments for a specific branches of the wood industry. Wood processing experiments were conducted to produce laths for construction purposes. These materials are one of the most important elements of roof constructions. The research proved empirically that it was possible to produce quality class 1 laths (88% of all laths produced) from WC0 class pinewood used as the input raw material and that the quantitative efficiency exceeded 55%.


2014 ◽  
Vol 156 (1) ◽  
pp. 3-12
Author(s):  
Ryszard MOSAKOWSKI

An analysis of balancing of V6 engines equipped with split-pin crankshafts with any cylinder bank angle based on the mathematical relations derived in the paper was carried out. A comparison of the quality of their balancing with engines equipped with common-pin crankshafts was also carried out. The bank angle ranges beneficial for balancing of moments of inertia forces in reciprocating motion were determined. A mathematical relation on the optimum value of the main counterweights in the function of the cylinder bank angle was derived as well. The advantages of the split-pin crankshafts from the point of view of balancing were also indicated also.


2021 ◽  
Vol 13 (23) ◽  
pp. 12963
Author(s):  
Nayeli Montalvo-Romero ◽  
Aarón Montiel-Rosales ◽  
Gregorio Fernández-Lambert ◽  
Fabiola Sánchez-Galván ◽  
Horacio Bautista-Santos

In its original manufacturing purpose, Expanded Polystyrene (EPS) is an industrial product with a short life cycle and waste with high negative environmental impact. Given this externality, this article contributes to the state of the art by proposing reuse EPS as a raw material valuable to the process of manufacturing hats in a Mexican company. The SCAMPER technique is used to formulate a hardener, which is optimized with a Taguchi design. Statistically, there is no difference between the quality of the conventional hardener and the mixture based on post-consumer EPS to make hats based on the standards defined by the company; a subjective analysis supported by the judgment of experts validates the quality of the hats. A contour graph and response surface reflect different combinations of solute and solvent to formulate the glue for the doping of the hat, with the same hardness results. This allows the artisan to assess the formulation from an economical point of view, as well as with respect to the arrangement of materials. These results specifically propose the sustainable alternative of integrating waste from the post–consumer EPS chain into the artisanal hat value chain, and are replicable to other similar products.


Processes ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1672
Author(s):  
Renata Stanisławczyk ◽  
Mariusz Rudy ◽  
Stanisław Rudy

Horsemeat has a strictly defined group of consumers whose demand varies depending on the country or region. There is no tradition of consuming horsemeat in Poland. From a technological point of view, this raw material is as good as other types of meat. In the opinion of the consumer, compared to other species of animals, horsemeat is characterized by an intense red-brown colour and greater cohesiveness resulting from the type of muscle fibres. This meat has a sweetish taste due to the high carbohydrate content. The management of horsemeat often involves the use of modern freezing methods. Freezing horsemeat with the use of liquefied carbon dioxide is a method that increases its suitability for consumption as well as for export purposes in comparison with the traditional air-cooling method. To eliminate the unfavourable quality features of horsemeat, there are substances used to improve the functional and sensory properties of this meat. This paper discusses the research and development work carried out in the field of horsemeat quality and selected methods contributing to its improvement.


Author(s):  
I. A. Ilina ◽  
I. A. Machneva ◽  
A. P. Chernutskiy

The work is devoted to the study of pectin extracts ultrafiltration  using different types of membranes. Pectic extracts are the solutions of high molecular weight polysaccharides (MM from 15 to 50 kDa), which are destroyed in the process of heat treatment in the vacuum evaporating apparature, that leads to a significant deterioration in the quality of pectin. The impurity components in the pectin extract of a low molecular weight, which makes it possible to use ultrafiltration for both concentration and purification from ballast substances, that  is very important. The objects of research were pectin extracts obtained from citrus raw materials; the membranes of the type UAM-100 and 200A were used as filter membranes. The results of the study have been shown, that the use of UAM-100 membranes in a stationary cell allows to remove up to 20% of the solution within 20 minutes, and with - stirring up to 27%. The use of membranes with large openings (up to 200 A) makes it possible to activate the process of the separation and concentration of pectin extracts: the degree of concentration reaches up 45%, the content of solids in the concentrate increases up to 7.6%, and the content of pectin to up 6.4%, that is in 1,7 times. However, the loss of low molecular weight pectin in the filtrate is about 4%. A comparative analysis of the results of research has shown a high productivity with the use of the capron membrane 200A, as well as on the qualitative parameters of the pectins, released from the concentrates, the higher parameters for the uroconid component, molecular weight, pectin jelly strength and complexing ability were noted for pectins isolated using the UAM- 100 membrane.


Author(s):  
E.V. Novikov ◽  
◽  
N.V. Basova ◽  
A.V. Bezbabchenko ◽  
◽  
...  

The paper presents a comparative analysis of domestic lines for primary processing of industrial spring harvesting hemp that is taken either from rolls or from stems in order to obtain raw material. The indicators of the quality of hemp raw materials and the hemp fiber of the same type obtained from it have been analyzed. The characteristics of the same type hemp and the process of its primary processing have been obtained, without which it is impossible to plan the primary processing of industrial hemp.


2020 ◽  
Vol 210 ◽  
pp. 02009
Author(s):  
Aleksander Lugovskoy ◽  
Sergey Gildenskiold ◽  
Tatjana Krylova ◽  
Nina Fomina

The paper assess marginal and control territories within the Moscow Metropolitan area using a comparative analysis of fluctuating asymmetry method and determining the area of leaf damage to obtain a comprehensive assessment of the territory from the point of view of human habitation with minimal comfort parameters within the sensitivity of plants. The results of the combined analysis of two methods are obtained, which confirm the possibility of their use and the representativeness of the results obtained in assessing the comfort of the environment. The assessment of the quality of the environment in marginal territories was made by quantitative and qualitative indicators for the rational use of land resources, their involvement in economic turnover with the creation of favorable conditions for ensuring the flow of social processes of territorial development and comfortable life support of the population. It was proposed that socially-oriented infrastructure, leisure facilities, and social and cultural facilities have been formed in these territories with a sufficiently large and diverse number of types and forms of employment for the population, which should become the basis for the development of marginal territories.


2018 ◽  
Vol 236 ◽  
pp. 02006
Author(s):  
Vladimír Konečný ◽  
Róbert Berežný ◽  
Mária Kostolná ◽  
Pavel Šaradín

The paper deals with the comparison of the importance of passengers’ requirements for the quality of the services provided and the quality assessment of air and bus transport. Individual quality criteria and their importance from the point of view of passengers vary depending on the mode of transport. It is also possible to observe the differing importance of quality criteria in relation to groups of passengers. The paper is processed comparison of the importance of individual quality criteria in air and bus services to the research in this area. In the paper is processed IPA matrix for air and bus transport. These are simple matrices that serve to highlight and understand important customer requirements.


2020 ◽  
Vol 1 (1) ◽  
pp. 59-64
Author(s):  
Ram Bahadur Gharti ◽  
Dipak Kumar Hitan ◽  
Manoj Kumar Prasad ◽  
Hari Bhakta Oli

Limestone is principal raw material for cement making industries. Chemical composition of limestone plays great role for making good quality cement. Production of good quality cement is of primary importance for the increment of the durability of infrastructure. Nepal is establishing large number of cement industries that uses limestone as raw materials and it is urgent to determine the quality of limestone. Quantitative Chemical analysis of one hundred forty three (143) limestone samples, collected by the channel sampling method, is carried out using gravimetric, titrimetric, and atomic absorption spectroscopic methods. The determined values of different parameters in percentages are as follows; loss on ignition (41.96385±0.670325), acid insoluble matter (2.412308±1.014588), Fe2O3 (0.263846±0.082249), Al2O3 (0.765385±1.656052), CaO (52.20538±1.656052) and MgO (3.018462±0.703886). The results indicated that most of the limestone samples are found to meet industrial raw material specifications for some industries. They can be used in the cement, agriculture (liming of soil and fish ponds) and metallurgical purification processes in the steel industry. Collected limestone samples meet the raw material specification of some industries. So establishment of such industries from a chemical point of view is feasible.


2019 ◽  
Vol 7 (2) ◽  
pp. 171-182
Author(s):  
Sara María Jaramillo-Carmona ◽  
Francisco Javier Tejero-Maján ◽  
Ana Jiménez-Araujo ◽  
Rafael Guillén-Bejarano ◽  
Rocío Rodríguez-Arcos

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