scholarly journals Effect of different oral doses of glucose on the blood serum content of serotonin in rats

2014 ◽  
Vol 68 (3) ◽  
pp. 87-92
Author(s):  
A. Yurchenko ◽  
V. Konopelniuk ◽  
E. Torgalo ◽  
O. Savchuk
Keyword(s):  
Blood Serum ◽  
Control Group ◽  
Oral Glucose ◽  
Glucose Content ◽  
Oral Doses ◽  
Positive Effect ◽  
Different Doses

The analysis of the effect of different doses of oral glucose content of serotonin in blood serum of rats. The increasing content of serotonin in blood serum of rats with diabetes and with the administration of glucose. The increase in the studied parameters in the serum of the control group of animals under conditions of glucose. It is concluded that glucose has a direct positive effect on the endogenous flow of serotonin into the bloodstream.

scholarly journals Evaluating the Effects of Gestational Diabetes Mellitus on Fetal Birth Weight

2020 ◽  
Vol 29 (2) ◽  
pp. 209-218
Author(s):  
Ahmed Faisal Sumit ◽  
Anindya Das ◽  
Shouvik Sarker ◽  
Joyshree Das
Keyword(s):  
Diabetes Mellitus ◽  
Birth Weight ◽  
Maternal Age ◽  
Control Group ◽  
Oral Glucose ◽  
Glucose Intake ◽  
Fetal Birth Weight ◽  
Positive Effect ◽  
Maternal Bmi ◽  
Duration Of Pregnancy

This study was aimed at evaluating the association between gestational diabetes mellitus (GDM) and fetal birth weight considering duration of pregnancy, maternal age and body mass index (BMI). This was a retrospective cross-sectional study followed by cohort type of study. Initially, pregnant women in their 24 to 28th week of gestation were selected for determining their fasting blood glucose (FBG) level and blood glucose level 2 hrs after 75 g oral glucose intake. The cut-off value for the diagnosis of GDM was > 5.3 mmol/l for FBG level and > 8.6 mmol/l for taking 75 g oral glucose intake after 2 hrs. Both GDM and control group subjects were followed up to neonatal period to find out neonatal outcomes. Among the total 215 subjects, 84 pregnant women were selected with GDM and rest 131 were control. It is found that GDM alone had a significant (p = 0.05) positive effect on both the duration of pregnancy and fetal birth weight, but not on maternal BMI. Both the effects of duration of pregnancy and GDM are considered together on fetal birth weight, only GDM had significant impact on fetal birth weight compared to the control group. Similarly, when the effect of maternal BMI and GDM is considered together on fetal birth weight, only GDM group was found to have significant effect on fetal birth weight. Parallel results were observed for the effect of both maternal age and GDM on fetal birth weight. In binary logistic regression analysis, when the differences are considered in maternal age, duration of pregnancy and maternal BMI along with GDM, both maternal age ≥ 35 years (OR: 9.43, p = 0.001) and GDM (OR: 10.60, p = 0.003) was found to have significant positive effect on fetal birth weight. It was found that the GDM showed significant influence on fetal birth weight considering the effects of maternal age, duration of pregnancy and maternal BMI. Dhaka Univ. J. Biol. Sci. 29(2): 209-218, 2020 (July)

Intra-articular Therapy of Osteoarthritis Using Drugs on the Base of Blood Serum

2010 ◽  
Vol 17 (2) ◽  
pp. 25-30
Author(s):  
Yu M Chernyakova ◽  
L S Pinchuk
Keyword(s):  
Single Dose ◽  
Knee Joint ◽  
Blood Serum ◽  
Test Group ◽  
Control Group ◽  
Local Inflammation ◽  
Biophysical Properties ◽  
Treatment Results ◽  
Positive Effect ◽  
And Cartilage

Comparison of biochemical composition and biophysical properties showed the pathogenetic expediency of blood serum use as a corrector of synovial environment in joints affected by osteoarthritis. For serum modification the patients were preliminary given a single dose of drug only. Then patient's blood was collected in the period of its maximum saturation by preparation. Serum obtained was applied in patients with knee joint osteoarthritis of 2-3 stages using three intra-articular injections. The evaluation of treatment results 5-6 months after treatment completion showed a significantly better and more stable therapeutic effect in test group as compared with patients from control group. Positive effect was stipulated by pain decrease, normalization of articular tissue trophicity, depression of local inflammation and cartilage lubrication improvement.

scholarly journals Influence of the probiotic preparation “Plantarum” in the diets of pregnant animals on the growth and development of young animals

2021 ◽  
Vol 37 ◽  
pp. 00143
Author(s):  
Irina Funk ◽  
Nikolay Vladimirov ◽  
Alexander Yashkin ◽  
Lyudmila Pautova ◽  
Vitaly Gorshkov
Keyword(s):  
Body Weight ◽  
Growth And Development ◽  
The Body ◽  
Control Group ◽  
Standard Diet ◽  
Absolute Increase ◽  
Probiotic Preparation ◽  
Positive Effect ◽  
Experimental Group ◽  
Different Doses

The work aims to study the effect of different doses of the experimental probiotic preparation “Plantarum” when fed to pregnant animals on their reproductive qualities, as well as on the growth and development of young animals. To obtain young animals, four groups of goats were formed in the type of the Saanen breed, 20 heads each. In the first (control) group, the animals received a standard diet, in the diet of the animals of the second, third and fourth groups in the second half of pregnancy, the probiotic preparation “Plantarum” was additionally introduced, containing Lactobacillus Plantarum, Propiobacterium freudenreihii, in dosages from 0.4 to 0.8 ml/kg of body weight per day. From the offspring of the goats of the experimental groups, four groups of 12 goats were formed. The highest percentage of preservation (94%) and the highest business output of kids per 100 queens (150%) were observed in the fourth experimental group (0.8 ml). The goats of the second, third and fourth groups exceeded the body weight of their contemporaries from the control group by 3%, 6.3%, and 8.8%. The highest indices of the absolute increase in body weight by age periods were noted in the fourth group of goats. There were no significant differences in body build indices during the experiment between the goats of the control and experimental groups. Thus, the maximum positive effect was observed with the introduction of a probiotic preparation into the diet of pregnant goats at a dose of 0.8 ml/kg of body weight per day.

scholarly journals Influence of B. bovis hairworms on biochemical parameters of blood of patients with bovicolosis of calves

2019 ◽  
Vol 21 (94) ◽  
pp. 163-168
Author(s):  
A. M. Shevchenko
Keyword(s):  
Blood Serum ◽  
Biochemical Parameters ◽  
Clinical Manifestations ◽  
Mean Value ◽  
Pathological Process ◽  
Control Group ◽  
Glucose Content ◽  
Normal Limits ◽  
Negative Effect ◽  
Biochemical Research

The purpose of the work was to identify the features of the pathological process and changes in the main indicators of blood of cattle for the damage by its hairworms B. bovis. Scientific researches were conducted in the conditions of the Ploskivske BPPZ of the Brovarsky District of the Kyiv Region and the Laboratory of Biochemical Research of the National Cancer Institute. To do this, two groups of young cattle, black-and-white breeds up to one year old with 7 heads in each, were created. The experimental group included calves spontaneously invasive with hairworms. The control group was free of animal parasites. For this, they were previously, in two months, subjected to two-fold treatment with Insecticide Tactics (MSD, the Netherlands). Selected animals on the principle of analogues. All calves were in the same sanitary and hygienic conditions and received the same feed according to the diet. It was found that the glucose content in a sick young bovine animal was 6.25% (P < 0.5) higher than that in calf-free calves. There was a probable difference in the level of urea in the blood of animals, where the average level in the infected calves was 12.69% (P < 0.001) higher than in the control animals. The tendency to decrease by 15.31% (P < 0.5) was found in the average values of serum creatinine in calves in sick animals compared with the group of animals that served as controls and were free from parasites. In blood serum, calves infected with hairworms was found a slightly higher (4.25%, P < 0.5) level of total bilirubin than those found free from parasites. Indicators of serum cholesterol levels in blood serum of experimental animals were within normal limits. However, it was significantly lower by 14.71% (P < 0.05) in animals affected by parasites. The albumin-globulin ratio in our studies in invasive calves was 9.8% (P < 0.01) higher than that of control animals. In experimental calves with clinical manifestations of bovycolous, the average index of alkaline phosphatase content was 17.58% (P < 0.5) lower than its mean value in blood serum free of invasion by parasites of animals. Thus, among the biochemical parameters of serum of blood of invasive calves, a probable increase in urea and albumin to globulin ratios and a decrease in cholesterol was observed, indicating a negative effect of the hairworms on the organism of animals.

scholarly journals Effects of oregano (Oreganumonites L.) aromatic water on rumen microbial fermentation of Holstein calves

2020 ◽  
Vol 44 (5) ◽  
pp. 1110-1114
Author(s):  
Serkan ÖZKAYA ◽  
Ozan Emre ALMALI ◽  
Yavuz AYAN ◽  
Sabri ERBAŞ ◽  
Taylan AKSU
Keyword(s):  
Rumen Fluid ◽  
Rumen Fermentation ◽  
Control Group ◽  
Ph Values ◽  
Rumen Ph ◽  
Holstein Calves ◽  
The Difference ◽  
Positive Effect ◽  
Total Bacteria ◽  
Different Doses

The study aimed to determine the effects of the addition of aromatic oregano water (AOW) on rumen fermentation of Holstein calves. For this purpose, 20 Holstein calves were divided into four groups (n = 5) and fed with three different doses of AOW (1, 1.5, and 2%). The experimental groups were formed as follows; the control group (CNT): milk + starter; G1: 1% AOW supplemented milk + starter; G2: 1.5% AOW supplemented milk + starter; G3: 2% AOW supplemented milk + starter. The rumen fluid was taken from the oesophagus at 60 days of age with the aid of a rumen probe. In acetic acid (AA), propionic acid (PA), and butyric acid (BA) except for total volatile fatty acid (TVFA) (P < 0.05), the numerical differences between the means of the groups were not found statistically significant. The rumen pH values of the groups were not affected by the addition of AOW. Likewise, the difference between the total bacteria and the numbers of protozoa, Entodinum, Diplodinium, Isotrichia, and Daystrichia were not statistically significant. The results of the study showed that the addition of AOW did not have a negative or positive effect on rumen fermentation of the calves.

scholarly journals Selenium content in the blood serum and urine of ewes receiving selenium-enriched unicellular alga Chlorella

2008 ◽  
Vol 52 (No. 1) ◽  
pp. 42-48 ◽  
Author(s):  
J. Travnicek ◽  
L. Pisek ◽  
I. Herzig ◽  
J. Doucha ◽  
J. Kvicala ◽  
...  
Keyword(s):  
Blood Serum ◽  
Post Partum ◽  
Average Concentration ◽  
Control Group ◽  
Selenium Content ◽  
Unicellular Alga ◽  
Organic Form ◽  
Pregnancy And Lactation ◽  
Positive Effect ◽  
Experimental Group

The effect of selenium supplementation in inorganic and organic form was investigated in three five-member groups of ewes and their lambs in the course of 7 months. The basal feed ration contained 55 &micro;g Se, ewes of experimental group E1 received a supplement of 180 &micro;g Se in sodium selenite, and ewes of experimental group E2 were applied a supplement of 180 &micro;g selenium bound in the biomass of the alga Chlorella. Control group C did not receive any selenium. The ewes were in the stage of non pregnant, pregnancy and lactation during the experiment. Average contents of Se in the blood serum of ewes were as follows: E1 114.2 &plusmn; 23.6; E2 103.1 &plusmn; 20.3; C 68.6 &plusmn; 16.8 &micro;g/l (<i>P</i> < 0.001). A decrease in serum Se was recorded in all groups in the last third of pregnancy and in the first week post partum. Average contents of urinary selenium contents were also higher in experimental groups: E1 25.4 &plusmn; 13.5; E2 18.7 &plusmn; 9.6; C 13.3 &plusmn; 4.5 &micro;g/l (<i>P</i> < 0.001). The positive effect of supplementation of Se to ewes was reflected in its higher average concentration in the blood serum of born lambs: E1 48.5 &plusmn; 7.3; E2 53.5 &plusmn; 3.4; C 30.3 &plusmn; 7.4 &micro;g/l (<i>P</i> < 0.05). The effect of selenium bound in Chlorella biomass was higher and persisted until 30 days of lamb age: E1 52.9 &plusmn; 3.4; E2 59.0 &plusmn; 7.0; C 35.5 &plusmn;5.8 &micro;g/l (<i>P</i> < 0.01). The average number of lambs born per ewe was 1.0 in group C and E1, and 1.8 in group E2.

scholarly journals Influence of cadmium sulfate at different doses on the functional state of the liver of laying chicken

2019 ◽  
Vol 21 (94) ◽  
pp. 103-108 ◽  
Author(s):  
A. Y. Ostapyuk ◽  
B. V. Gutyj
Keyword(s):  
Body Weight ◽  
Blood Serum ◽  
Functional State ◽  
The Body ◽  
Control Group ◽  
Cadmium Sulfate ◽  
Group 4 ◽  
Group 2 ◽  
Destructive Processes ◽  
Different Doses

The article presents the results of studies on the influence of cadmium sulfate in different doses on the organism of poultry. Absorbed cadmium accumulates in the liver as a complex with metallothionein. The purpose of the work was to find out the effect of cadmium sulfate in doses of 2 and 4 mg / kg of body weight on the functional state of the liver of chicken. For research, three groups of birds were formed: control and two experimental. The control group of chickens were in the usual diet, they were fed with forage and were given water without introducing cadmium sulfate. To the drinking water of chickens of experimental groups for 30 days, added cadmium sulfate in doses: the first group – 2 mg/kg, the second group – 4 mg/kg body weight. The conditions for keeping chickens and the microclimate parameters in the room for all bird groups were similar. Blood from the chickens was taken from the subclavian vein in periods: before the dasg was given and on the first, seventh, fourteenth, twenty-first and thirtieth day of the experiment. It was determined that the presentation of cadmium sulfate in doses of 2 and 4 mg/kg of body weight of cows, which contributed to a violation of the functional state of the liver, as evidenced by the increased activity of aminotransferases in their blood serum. The activity of alanine and aspartate aminotransferase was higher in serum of blood of chickens in the second experimental group at 21st and 30th days of the experiment. The high activity of aminotransferases in the blood serum of chickens for cadmium loading indicates destructive processes in the liver that cause an increase in the release of aminotransaminases from cellular organelles in the blood of experimental poultry. Thus, the obtained results indicate an increase in destructive processes in the body of chickens for cadmium loading.

scholarly journals Effect of L-glutamic acid on some biochemical parameters of rat blood under the action of sodium nitrite

2016 ◽  
Vol 20 (1) ◽  
pp. 74-77
Author(s):  
N. Salyha ◽  
R. Iskra
Keyword(s):  
Antioxidant Enzymes ◽  
Glutamic Acid ◽  
Sodium Nitrite ◽  
Biochemical Parameters ◽  
Control Group ◽  
Glucose Content ◽  
Rat Blood ◽  
Blood Biochemical Parameters ◽  
Blood Biochemical ◽  
Different Doses

The effect of different doses of L-glutamic acid on activity of antioxidant enzymes and some blood biochemical parameters in rats under the influence of sodium nitrite was studied. It was shown that administration of sodium nitrite leads to decreased activity of antioxidant enzymes and and hemoglobin and glucose content in the blood of animals.It was established, that changes of studied parameters were less expressed in rats administered of L-glutamic acid compared to the control group of animals.

scholarly journals Dynamics of some indicators of blood serum in case of digestive disordersin calves in the early postnatal period

2020 ◽  
Vol 222 ◽  
pp. 02026
Author(s):  
M.S. Mannova ◽  
L.V. Kletikova ◽  
N.N. Yakimenko ◽  
K.A. Voronova
Keyword(s):  
Blood Serum ◽  
Protein Metabolism ◽  
Animal Husbandry ◽  
Blood Parameters ◽  
Postnatal Period ◽  
Early Postnatal Period ◽  
Control Group ◽  
Urgent Problem ◽  
Digestive Disorders ◽  
Positive Effect

Digestive disorders in calves are an urgent problem in animal husbandry. The purpose of this study was to evaluate the properties of enterosorbent and its effect on blood parameters in calves with digestive disorders. The study revealed the dynamics of total protein, albumin, globulins, protein coefficient, glucose, transaminases, creatine kinase in the blood serum of calves with digestive disorders in the early postnatal period against the background of the use of methylsilicic acid hydrogel as an intestinal sorbent. The use of enterosorbent at a dose of 0.5 g/kg for 7 days had a positive effect on protein metabolism: the concentration of albumin increased by 10.40%, the content of globulins decreased by 11.20%. The activity of AST serum against the background of the use of enterosorbent was lower by 14.40% than in the control group, which indicates the detoxification properties of the drug used.

scholarly journals BULLS CONSUMPTION AND USE OF DIET SUBSTANCES BY PROBIOTICS VETOSPORIN SUSPENSION

2018 ◽  
pp. 43-48
Author(s):  
Фаргат Вагапов ◽  
Fargat Vagapov ◽  
Наталья Гизатова ◽  
Natalya Gizatova
Keyword(s):  
Feed Intake ◽  
Live Weight ◽  
The Body ◽  
Control Group ◽  
Feed Supplement ◽  
Group I ◽  
Bull Calves ◽  
Positive Effect ◽  
Young Growth ◽  
Different Doses

The purpose of research is increase the efficiency of the use of nutrients for rations by Simmental breed bulls with various doses of Vetosporin Suspension. Bulls were fed by probiotic in the amount of 0.1; 1 and 2 ml per 10 kg of live weight. It has been established that the use of rations including the feed supplement studied, in the feeding of experimental groups, promoted an increase in feed intake. Thus, the young growth of the three experimental groups exceeded the analogues of the control group for the consumption of hay grass by 37-118 kg (1.47-4.68%), green weight – by 31-71 kg (1.74-3.98%). Concentrates, molas-ses, fodder, and salt were given to the animals in the same amount. It can be stated that feeding to the Simmental bulls of different doses of the Vetosporin drug suspension had a positive effect on the digestibil-ity of the nutrients of the diet and their assimilation by the body. It is evident that in animals of experimental groups there is a certain superiority in certain indices over analogues of the control group. In this case, the animals of group I were inferior to the experimental groups by a digestibility factor of 1.03-2.24%, raw fat by 0.43-0.77%. For the rest of the indicators, there was a similar trend. When fattening Simmental bull calves, full-fledged and, importantly, balanced feeding was organized. Taking this into account, the use of probiotic fodder supplement, Vetosporin Suspension, contributed to greater consumption of all types of feed, nutrients and energy by animal test groups. In this case, the greatest effect was observed with the use of an approved additive in a dose of 1.0 ml per 10 kg of alive weight.

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