scholarly journals COVID-19 and Its Pathophysiology

2021 ◽  
Vol 58 (2) ◽  
pp. 487-494
Author(s):  
Anubhuti Dixit, Dr. Swaroopa Chakole
Keyword(s):  
Health Care ◽  
Disease Management ◽  
The Novel ◽  
Research Needs ◽  
The Earth ◽  
Health Care Infrastructure ◽  
Containment Strategy ◽  
Novel Coronavirus

BACKGROUND COVID-19 or coronavirus disease is seriously affecting the daily lifestyle of the inhabitants of the earth. It had already created so much disturbances in terms of lives as well as livelihood. SUMMARY The constantly changing epidemiology and its pathophysiology of the coronavirus also known as SARS-COV-2 is creating problems in designing the containment strategy. Symptoms have changes so far since its inception in Wuhan, china. Disease management has been not all success as high virulent nature of the novel coronavirus has left the health care infrastructure overwhelmed with millions of case. The long term implications are also staring in the eyes of the researchers and needs to be solved before gaining traction. CONCLUSION Highly uncertain nature of novel coronavirus has been demanded greater focus on constant research. More research needs to be done in order to catalogue all the features of the virus whether changing or constant.

scholarly journals Outpatient management of heart valve disease following the COVID-19 pandemic: implications for present and future care

Heart ◽  
2020 ◽  
Vol 106 (20) ◽  
pp. 1549-1554 ◽  
Author(s):  
Benoy Nalin Shah ◽  
Dominik Schlosshan ◽  
Hannah Zelie Ruth McConkey ◽  
Mamta Heena Buch ◽  
Andrew John Marshall ◽  
...  
Keyword(s):  
Heart Valve ◽  
Waiting Times ◽  
Severe Disease ◽  
Valve Disease ◽  
Heart Valve Disease ◽  
The Novel ◽  
Future Care ◽  
Novel Coronavirus

The established processes for ensuring safe outpatient surveillance of patients with known heart valve disease (HVD), echocardiography for patients referred with new murmurs and timely delivery of surgical or transcatheter treatment for patients with severe disease have all been significantly impacted by the novel coronavirus pandemic. This has created a large backlog of work and upstaging of disease with consequent increases in risk and cost of treatment and potential for worse long-term outcomes. As countries emerge from lockdown but with COVID-19 endemic in society, precautions remain that restrict ‘normal’ practice. In this article, we propose a methodology for restructuring services for patients with HVD and provide recommendations pertaining to frequency of follow-up and use of echocardiography at present. It will be almost impossible to practice exactly as we did prior to the pandemic; thus, it is essential to prioritise patients with the greatest clinical need, such as those with symptomatic severe HVD. Local procedural waiting times will need to be considered, in addition to usual clinical characteristics in determining whether patients requiring intervention would be better suited having surgical or transcatheter treatment. We present guidance on the identification of stable patients with HVD that could have follow-up deferred safely and suggest certain patients that could be discharged from follow-up if waiting lists are triaged with appropriate clinical input. Finally, we propose that novel models of working enforced by the pandemic—such as increased use of virtual clinics—should be further developed and evaluated.

scholarly journals The coronavirus in the MENA region: Enhancing turbulence or mitigating conflicts?

European View ◽  
2020 ◽  
Vol 19 (2) ◽  
pp. 206-211
Author(s):  
Magnus Norell
Keyword(s):  
Middle East ◽  
The Novel ◽  
Crisis Preparedness ◽  
Mena Region ◽  
Existing Problems ◽  
Regional Conflicts ◽  
Current Trends ◽  
Short And Long Term ◽  
Novel Coronavirus

The novel coronavirus (COVID-19) pandemic has affected the countries in the Middle East and North Africa (MENA) region in different ways, and the varying political structures, economic conditions and civil-crisis preparedness of the states in this region have resulted in it being handled in a variety of ways too. Even if it is difficult to assess how the crisis has affected the MENA region in more detail due to the region’s general volatility and ongoing conflicts in Libya and Syria, current trends have so far not shown a diminution in regional conflicts. Nor have the pandemic’s consequences in the Middle East lessened Europe’s problems with the region. Thus the article argues that COVID-19 has not really led to a decrease in the conflicts and wars plaguing the MENA region, and that, therefore, the effects for Europe—both short- and long-term—will still be felt, as existing problems will continue to affect Europe.

scholarly journals The impact of novel COVID-19 initial pandemic on orthopedic healthcare: an experience from a single institution of South Korea

2021 ◽  
Vol 64 (11) ◽  
pp. 778-787
Author(s):  
Gun Woo Lee ◽  
Gi Beom Kim ◽  
In Jun Lee
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Medical Staff ◽  
Healthcare Workers ◽  
The Novel ◽  
Preventive Surgery ◽  
Care Workers ◽  
Cancellation Rate ◽  
Novel Coronavirus ◽  
The Impact

Background: This study was to investigate the cancellation rate and trend of orthopedic surgeries during the novel coronavirus disease 2019 (COVID-19) pandemic. Moreover, we assessed the psychologic status of orthopedic healthcare workers, and investigated the details of the preventive surgeries underwent in COVID-19-positive patients.Methods: For 3 months after January 20, 2020, cancellation rates of elective surgeries were investigated, and the number of elective surgeries conducted in the same period over the last two years was compared. Four different questionnaires were used to investigate psychologic status among the orthopedic health care workers. We compared the outcomes according to occupation (physician or nurse), and type of work (faculty staff or resident physician). Outcomes according to occupation and type of work were compared. Preventive surgeries underwent in patients who could not wait for the results of the COVID-19 diagnosis were investigated.Results: Spine and hip surgery had relatively lower cancellation rates, and elective surgeries were significantly reduced. During the initial pandemic, the cancellation rate of orthopedic elective surgeries was significantly higher than in the same period of the previous year and was different for each subdivision depending on the degree of pain or disability. The psychological outcomes were within the normal range and there were no significant differences between groups. After preventive surgery, all medical staff involved in the operation tested negative.Conclusion: During the COVID-19 pandemic, the cancellation rate of orthopedic elective surgeries was significantly higher than in the same period of the previous year. Orthopedic health care workers did not seem to have significant psychological distress. As a result of the preventive surgery in specialized facilities, all the medical staff who participated in the operation tested negative.

scholarly journals Pharmacotherapeutic approach toward urological medications and vaccination during COVID-19: a narrative review

2021 ◽  
Vol 13 ◽  
pp. 175628722110467
Author(s):  
Mojtaba Shafiekhani ◽  
Anahita Dehghani ◽  
Mina Shahisavandi ◽  
Seyed Ali Nabavizadeh ◽  
Maryam Kabiri ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Kidney Transplantation ◽  
Prostatic Hyperplasia ◽  
Narrative Review ◽  
The Novel ◽  
Urologic Diseases ◽  
One Year ◽  
Novel Coronavirus ◽  
Comprehensive Study

One year after the prevalence of the novel coronavirus pandemic, some aspects of the physiopathology, treatment and progression of coronavirus 2019 disease (COVID-19) have remained unknown. Since no comprehensive study on the use of urological medications in patients with COVID-19 has been carried out, this narrative review aimed to focus on clinically important issues about the treatment of COVID-19 and urologic medications regarding efficacy, modifications, side effects and interactions in different urologic diseases. In this review, we provide information about the pharmacotherapeutic approach toward urologic medications in patients with COVID-19 infection. This study provides an overview of medications in benign prostatic hyperplasia, prostate cancer, impotence and sexual dysfunction, urolithiasis, kidney transplantation and hypertension as the most frequent diseases in which the patients are on long-term medications. Also, the effect of urologic drugs on the efficacy of vaccination is briefly discussed.

scholarly journals New Surgical Practice During COVID 19

2021 ◽  
Vol 28 (05) ◽  
pp. 614-618
Author(s):  
Mohammad Sohail Asghar ◽  
Hafiz Syed Zaigham Ali Shah ◽  
Hamna Khan ◽  
Aima Zahid ◽  
Hammad Zia ◽  
...  
Keyword(s):  
Health Care ◽  
Care Staff ◽  
Health Care Staff ◽  
Sufficient Information ◽  
The Novel ◽  
Care Workers ◽  
Medical Teams ◽  
Novel Coronavirus ◽  
Spread Of Infection ◽  
Transmission Of Disease

A sequence of pneumonia-causing diseases from the Novel coronavirus (COVID-19) appeared in Wuhan, Hubei, China in December 2019. The outbreak of COVID-19 spread quite rapidly. Just as we write this report, almost two and a half million verified cases were reported globally, and almost 180,000 people died.1 Experience from China reveals that COVID-19 outbreaks can be brought under control within 3 months, with highly efficient touch tracking and case isolation.2 Healthcare staff are at the forefront of treatment for COVID-19 cases and have a very large chance of exposure to the infection.3 Cuts in disposable gear and COVID-19 awareness are triggering infections in healthcare workers.4 As of February 11, 2020, China has contaminated more than 1,700 health-care workers. In Italy, 2026 (9 percent) of the COVID-19 incidents happened in healthcare professionals (as of March 15).5 But, 31 medical teams containing more than 42,000 nurses and doctors sent by the Hubei from other provinces did not have a reported infection. It indicates that sufficient information about the transmission of disease and the use of protective equipment and procedures to manage infections is necessary to avoid the spread of infection among health care staff.

scholarly journals COVID-19 Pandemic: Impact of Quarantine on Medical Students’ Mental Wellbeing and Learning Behaviors

2020 ◽  
Vol 36 (COVID19-S4) ◽  
Author(s):  
Sultan Ayoub Meo ◽  
Dr Abdulelah Adnan Abukhalaf ◽  
Ali Abdullah Alomar ◽  
Kamran Sattar ◽  
David C Klonoff
Keyword(s):  
Medical Students ◽  
Work Performance ◽  
Mental Wellbeing ◽  
Psychological Wellbeing ◽  
The Novel ◽  
Learning Behaviors ◽  
Creative Commons ◽  
Novel Coronavirus ◽  
The Impact

Background and Objectives: The novel coronavirus COVID-19 pandemic causes great public health and socioeconomic harms. Worldwide many countries implemented quarantine policies to minimize the spread of this highly contagious disease. The present study aim was to investigate the impact of quarantine on the medical students’ mental wellbeing and learning behaviors. Methods: In this descriptive study, we used a questionnaire with a Five-Point Likert Scale to collect the information. The questionnaire was distributed among 625 medical students through their emails with a response rate of 530 (84.8%), majority 294 (55.47%) being female. The survey questionnaire consisted of total 20 items; 12 items were related to psychological wellbeing and stress-allied queries and 08 items were about learning behaviors. Results: The findings encompass two important characteristics related to quarantine, psychological wellbeing, and learning behaviors. A combined cohort of 234 medical students, either female or male, (which was 44.1% of the total responders) showed a sense of being emotionally detached from family, friends and fellow students, 125/ 530 (23.5%) medical students felt disheartened. Both female and male medical students showed a marked decrease in their overall work performance. Moreover, 56.2% of the total students (61.5% of the females and 49.5% of the males) felt a decrease in the time they spent studying. Conclusions: Both female and male medical students have identified that quarantine has caused them to feel emotionally detached from family, fellows, and friends and decrease their overall work performance and study period. The findings also show that one-fourth of the medical students who participated in this study felt disheartened during the quarantine period. The long-term quarantine due to COVID-19 pandemic may causes further worsening in the psychological and learning behaviors of these medical students. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2809 How to cite this:Meo SA, Abukhalaf AA, Alomar AA, Sattar K, Klonoff DC. COVID-19 Pandemic: Impact of Quarantine on Medical Students’ Mental Wellbeing and Learning Behaviors. Pak J Med Sci. 2020;36(COVID19-S4):---------. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2809 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Formulating a Scalable Approach to Patron-Requested Digitization in Archives

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Kevin S. Hawkins ◽  
Julie Judkins
Keyword(s):  
Risk Assessment ◽  
Copyright Law ◽  
The Novel ◽  
Long Distance ◽  
Novel Coronavirus ◽  
Distance Travel ◽  
Long Distance Travel

The novel coronavirus of 2019 (COVID-19) crisis has forced archives to rethink their modes of providing access to physical collections. Whereas difficult copyright questions raised by reproducing items could previously be skirted by requiring researchers to work with materials in person, the long-term closure of reading rooms and decrease in long-distance travel mean that archives need a workflow for handling user digitization requests that is scalable and requires consulting only easily identifiable information and, assuming full reproduction is off the table, reproducing items in a collection under 17 U.S.C. § 108 or through a strategy of rapid risk assessment. There is a challenge in creating a policy that will work across different formats and genres of archival materials, so this article offers some suggestions for how to think about these parameters according to US copyright law and calls for a committee of experts to work out a model policy that could serve remote users of archival collections even after the COVID-19 crisis has passed.

scholarly journals The Covid-19 Pandemic and its Effect on the Elderly: A Review

2020 ◽  
Vol 5 (3) ◽  
Author(s):  
Maimoona Nadri ◽  
Ujala Zubair
Keyword(s):  
The Elderly ◽  
Medical Community ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Public Health Concern ◽  
The World ◽  
Long Term Consequences ◽  
Novel Coronavirus

In 2019, the world experienced a global public health concern when the novel coronavirus originated from China and affected around fifty-seven thousand people around the world by March 2020. The quick rise in the number of cases and the death toll overwhelmed the scientific and medical community. While all the focus was driven towards finding the epidemiology, the treatment and the management, the mental health aspect of the quarantine was being overlooked. The purpose of this review is to create awareness about the long-term consequences of quarantine, with the focus on the elderly community in Pakistan. 

scholarly journals Acute respiratory infections in outpatient care in the era of the COVID-19 pandemic: the role and position of antibacterial therapy

2020 ◽  
Vol 4 (4) ◽  
pp. 214-218
Author(s):  
R.F. Khamitov ◽  
Keyword(s):  
Health Care ◽  
Outpatient Care ◽  
Viral Infections ◽  
Respiratory Infections ◽  
Respiratory Viruses ◽  
Acute Respiratory Infections ◽  
The Novel ◽  
Coronavirus Infection ◽  
Novel Coronavirus ◽  
Care Costs

Acute respiratory infections of the upper and lower respiratory tract are currently the leading cause of human morbidity, mainly due to the seasonal rise of the incidence rates of viral infections. This results in the heavy burden of annual health care costs. The COVID-19 pandemic exacerbated the problem. The associations between respiratory viruses and bacteria are not always clear thus accounting for the diversity of the risks of the complicated course and fatal outcomes of various bacterial viral coinfections. Influenza virus is associated with the high rate of bacterial complications (in particular, during seasonal peaks). Meanwhile, this is less typical of the novel coronavirus infection. In addition, several studies demonstrate the competitive edge of SARS-CoV-2 when interacting with other respiratory viruses. The specificities of viral bacterial associations greatly affect the treatment whose inadequacy (in particular, the prescription of antibiotics) is the leading cause of the increasing antimicrobial resistance of contemporary germs. The novel coronavirus infection SARS-CoV-2 is no exception in terms of inappropriate antibiotic prescribing as occurred often in the seasonal rise of acute respiratory viral infections. The understanding of this issue, the optimization of treatment strategies, and a reduction in health care costs will allow for preserving antibiotics as a class of highly effective medications. KEYWORDS: acute respiratory infections, COVID-19, bacterial coinfection, outpatient care, lung damage, antimicrobial therapy. FOR CITATION: Khamitov R.F. Acute respiratory infections in outpatient care in the era of the COVID-19 pandemic: the role and position of antibacterial therapy. Russian Medical Inquiry. 2020;4(4):214–218. DOI: 10.32364/2587-6821-2020-4-4-214-218.

scholarly journals Application of Optimal Control to Long Term Dynamics of COVID-19 Disease in South Africa

2020 ◽  
Author(s):  
Farai Nyabadza ◽  
Williams Chukwu ◽  
Faraimunashe Chirove ◽  
fatmawati fatmawati ◽  
Princess Gatyeni
Keyword(s):  
South Africa ◽  
Optimal Control ◽  
South African ◽  
Control Measures ◽  
The Novel ◽  
Public Health Importance ◽  
Mathematical Analyses ◽  
Novel Coronavirus ◽  
Control And Management

SARS-CoV-2 (COVID-19) belongs to the beta-coronavirus family, these include; the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). Since its resurgence in South Africa in March 2020, it has lead to high mortality and thousands of people contracting the virus. In this study, we use a set of five differential equations to analyse the effects on long term dynamics of COVID-19 pandemic with optimal control measures. Mathematical analyses of the model without control were done and the basic reproduction number (R0) of the COVID-19 for the South African epidemic determined. The model steady states were also determined, and their analyses presented based on R0: We introduced permissible control measures and formulated an optimal control problem using the Pontraygain Maximum Principle. Our numerical findings suggest that joint implementation of effective mask usage, physical distancing and active screening and testing are effective measures to curtail the spread of the disease on undiagnosed humans. The results obtained in this paper are of public health importance in the control and management of the spread for the novel coronavirus, SARS-CoV-2, in South Africa.

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