Gender features of age-related risk of mortality associated with nervous diseases

Aim. To explore the hypothesis of equal age-related risk of mortality associated with nervous diseases in females and males. Methods. Descriptive statistics, qualitative analysis were performed. 13 580 medical certificates of cause of death, all related to nervous diseases (all classes of ICD-10) were analyzed. Results. The mortality rate increased with age. Age-specific mortality rates had gender differences. In most ages (20-24, 30-34, 45-49, 50-54, 55-59, 65-69), mortality rate was higher in males, at the age of 5-9, 15-19, 60-64, 70 and over - in females. Death relative risk in males of different age groups (compared to the similar rates in females) varied between 0.39 (in the age group of 5-9 years) to 5.93 (in patients aged 20-24 years). Overall, the level of mortality associated with nervous diseases was 130.02±1.69 per 100 000 in males and 163.41±1.86 per 100 000 in females, so, overall mortality rate was 1.25 times higher in females. After adjustment for age differences was performed, no significant differences were found between the groups (146.74 and 144.16 per 100 000 respectively for males and females). Conclusion. Gender features of age-related risk of mortality associated with nervous diseases were characterized by multidirectional alterations of mortality rates and share of nervous diseases among all reasons of mortality. These features were mainly caused by situational factors (different age structure and overall mortality level for males and females), and vanished after adjustment.

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Trends in the drowning mortality rate in Iran

Injury Prevention ◽

10.1136/injuryprev-2019-043225 ◽

2019 ◽

Vol 26 (4) ◽

pp. 351-359

Author(s):

Pegah Derakhshan ◽

Sahar Saeedi Moghaddam ◽

Soheil Saadat ◽

Ali Ghanbari ◽

Nazila Rezaei ◽

...

Keyword(s):

Mortality Rate ◽

Age Groups ◽

Mortality Rates ◽

Global Burden ◽

Data Set ◽

Time Period ◽

Males And Females ◽

Disease Study ◽

Death By Drowning ◽

Burden Of Diseases

ObjectiveThe WHO estimates the global incidence of death by drowning to be about 300 000 cases per year. The objective of this study was to estimate the trend in mortality due to drowning in all provinces of Iran in all age groups and both genders from 1990 to 2015.Study designThe National and Subnational Burden of Diseases (NASBOD) project is a comprehensive project in Iran. It is based on the Global Burden of Disease study and includes novel methods to estimate the burden of diseases in Iran.MethodsThis study used the results of the mortality rate due to drowning as part of NASBOD and investigated the causes behind the mortality rates. The data set recorded mortality rates by 19 age groups and two genders with the corresponding subnational pattern during the time period from 1990 to 2015.ResultsThe drowning mortality rate decreased in Iran from 1990 to 2015. From 1990 to 2015, the annual percentage change for males and females was −5.28% and −10.73%, respectively. There were 56 184 male and 21 589 female fatalities during the study period. The highest number of deaths was seen in 1993 with 4459, and the lowest number of fatalities was observed in 2015 with 903 deaths.ConclusionOur data showed a decline in drowning mortality in Iran from 1990 to 2015, but the rates and declines varied by province. Our findings are of great importance to health officials and authorities in order to further reduce the burden of drowning.

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Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

10.21203/rs.2.13926/v4 ◽

2020 ◽

Author(s):

Fatemeh Khosravi Shadmani ◽

Farshad Farzadfar ◽

Moein Yoosefi ◽

Kamyar Mansori ◽

Reza Khosravi Shadman ◽

...

Keyword(s):

Mortality Rate ◽

Age Groups ◽

Premature Mortality ◽

Mortality Rates ◽

Mortality Trends ◽

Control Plan ◽

Liver Cancers ◽

Colon And Rectum ◽

Gi Cancers ◽

Overall Mortality

Abstract Background: The present study was conducted to determine the trend and projection of premature mortality from gastrointestinal cancers (GI cancers) at national and subnational levels in Iran.Methods: Employing the data obtained from Iranian Death Registry System (DRS) and population data from census, the mortality rates of GI cancers was calculated among 30-70 age groups. The trends of esophageal, colon and rectum, gallbladder, pancreases, stomach, and liver cancer premature mortalities were estimated and projected at the national and subnational levels from 2001 to 2030. Then, Spatio-temporal model was used to project spatial and temporal correlations. Results: The overall mortality rate of GI cancers was higher in males than in females, indicating 6.1, 3.9 and 3.9 percent per 100000 individuals among males in 2001, 2015 and 2030 respectively and 3.8, 3.1 and 3.7 per 100000 individuals among females in the same time-frame. The overall mortality rate of GI cancers in males was decreasing until 2015 and will remain stationary into 2030; however, the rate will be increasing among females in both time-frames. Also, there was a considerable variation in the mortality trends of different cancers. Pancreatic, gallbladder, and liver cancers were shown to have an increasing trend while a drop was observed in the mortality rates of stomach, colon and rectum, and esophageal cancers. Conclusion: Variation of GI cancers patterns and trends around the country indicated that a more comprehensive control plan is needed to include the predicted variations.

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Premature Mortality of Gastrointestinal Cancer in Iran: Trends and Projections for 2001–2030

10.21203/rs.2.13926/v3 ◽

2020 ◽

Author(s):

Fatemeh Khosravi Shadmani ◽

Farshad Farzadfar ◽

Moein Yoosefi ◽

Kamyar Mansori ◽

Reza Khosravi Shadman ◽

...

Keyword(s):

Mortality Rate ◽

Age Groups ◽

Premature Mortality ◽

Mortality Rates ◽

Mortality Trends ◽

Control Plan ◽

Liver Cancers ◽

Colon And Rectum ◽

Gi Cancers ◽

Overall Mortality

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Outcome in an Urban Pediatric Trauma System with Unified Prehospital Emergency Medical Services Care

Prehospital and Disaster Medicine ◽

10.1017/s1049023x00041601 ◽

1995 ◽

Vol 10 (1) ◽

pp. 19-23 ◽

Cited By ~ 11

Author(s):

Michael J. VanRooyen ◽

Edward P. Sloan ◽

John A. Barrett ◽

Robert F. Smith ◽

Hernan M. Reyes

Keyword(s):

Head Injury ◽

Mortality Rate ◽

Trauma Center ◽

Pediatric Trauma ◽

Trauma System ◽

Age Groups ◽

Mortality Rates ◽

Trauma Centers ◽

Field Triage ◽

Pediatric Trauma Center

AbstractHypothesis:Pediatric mortality is predicted by age, presence of head trauma, head trauma with a low Glasgow Coma Scale (GCS) score, a low Pediatric Trauma Score (PTS), and transport directly to a pediatric trauma center.Population:Studied were 1,429 patients younger than 16 years old admitted to or declared dead on arrival (DOA) in a pediatric trauma center from January through October, 1988. The trauma system, which served 3-million persons, included six pediatric trauma centers.Methods:Data were obtained by a retrospective review of summary statistics provided to the Chicago Department of Health by the pediatric trauma centers.Results:Overall mortality was 4.8% (68 of 1429); 32 of the patients who died (47.1%) were DOA. The in-hospital mortality rate was 2.6%. Head injury was the principal diagnosis in 46.2% of admissions and was a factor in 72.2% of hospital deaths. The mortality rate was 20.3% in children with a GCS≤10 and 0.4% when the GCS was >10 (odds ratio [OR] = 67.0, 95% CI = 15.0–417.4). When the PTS was ≤ 5, mortality was 25.6%; with a PTS > 5, the mortality was 0.2% (OR = 420.7, 95% CI = 99.3–2,520). Although transfers to a pediatric trauma center accounted for 73.6% of admissions, direct field triage to a pediatric trauma center was associated with a 3.2 times greater mortality risk (95% CI = 1.58–6.59). Mortality rates were equal for all age groups. Pediatric trauma center volume did not influence mortality rates.Conclusions:Head injury and death occur in all age groups, suggesting the need for broad prevention strategies. Specific GCS and PTS values that predict mortality can be used in emergency medical services (EMS) triage protocols. Although the high proportion of transfers mandates systemwide transfer protocols, the lower mortality in these patients suggests appropriate EMS field triage. These factors should be considered as states develop pediatric trauma systems.

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Treatment of cyanotic heart diseases in children

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh04s1009j ◽

2004 ◽

Vol 132 (suppl. 1) ◽

pp. 9-13

Author(s):

Ida Jovanovic ◽

Vojislav Parezanovic ◽

Slobodan Ilic ◽

Djordje Hercog ◽

Milan Vucicevic ◽

...

Keyword(s):

Heart Disease ◽

Mortality Rate ◽

Surgical Procedures ◽

Heart Surgery ◽

Heart Diseases ◽

Arterial Switch Operation ◽

Open Heart Surgery ◽

Age Groups ◽

Mortality Rates ◽

Cyanotic Heart Disease

Cyanotic heart diseases are relatively rare, but they are severe and heterogeneous congenital heart diseases, which require complex surgery. Development of different advanced surgical procedures, such as arterial switch operation (ASO), Fontan and its modifications, Norwood etc. operations, as well as better perioperative care significantly improved survival rate and quality of life of these children. The study group included 308 children treated for cyanotic heart disease in Yugoslavia, in the period January 2000 to July 2004. Some of them (239, 77.6%) were treated at the University Children?s Hospital in Belgrade, and others (69, 22.4%) in different institutions abroad. The age of the operated patients varied between 1 day and 19 years (median 12 months). The patients (pts) were divided into four groups, according to the disease and type of the operation. In the whole group of 308 patients treated due to cyanotic heart disease, there were 232 (75.3%) cases with open heart surgery and 76 (24.7%) with closed procedures. The mortality rate was significantly different between disease/operation groups, and age groups. Average mortality rates differed from 11.8% for palliative procedures to 12.5% for complete corrections. Mortality rate and achieved surgical results in treatment of chil?dren with cyanotic heart diseases were significantly worse than those published by leading cardiac surgery centers in the world. However, there is a clear tendency in introducing new surgical procedures, lowering the age at which the operation is done and decreasing the mortality rates.

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Mortality from endometrial cancer in female population of Belgrade

Vojnosanitetski pregled ◽

10.2298/vsp0403267p ◽

2004 ◽

Vol 61 (3) ◽

pp. 267-272

Author(s):

Vesna Pantovic ◽

Mirjana Jarebinski ◽

Tatjana Pekmezovic ◽

Anita Knezevic ◽

Darija Kisic

Keyword(s):

Endometrial Cancer ◽

Mortality Rate ◽

Malignant Tumors ◽

Age Groups ◽

Mortality Rates ◽

Mortality Decline ◽

Female Population ◽

Average Percentage ◽

Standardized Mortality Rate

Data about mortality from malignant tumors of endometrium were analyzed in the Belgrade area during the period 1975-2000. The obtained results showed that the average percentage of endometrial cancer in mortality structure from all the cancers of female population was 2.65%. During the observed 26-years period, malignant tumors of endometrium constituted 17.38% of all the tumors of gynecological localization. The standardized mortality rate in 1975 (population worldwide used as a standard) 7.06/100 000 population while in 2000 it was 1.78/100 000 population, respectively, which showed almost fourfold mortality decline during the observed period (y=4.72-0.16x). A trend of declining risk of dying from endometrial cancer was present in all the age groups. The obtained results indicated that in the observed period the average mortality rates ranged from 0.14/100 000 population in females aged up to 34 years (y=0.30-0.01x), and reached the highest value in females aged 65-74 years (14.57/100 000; y=23.43-0.66x), and 75 years of age and over (19.62/100 000; y=31.17-0.85x).

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Age-Related Risk Factors and Complications of Patients With COVID-19: A Population-Based Retrospective Study

Frontiers in Medicine ◽

10.3389/fmed.2021.757459 ◽

2022 ◽

Vol 8 ◽

Author(s):

Han Zhang ◽

Yingying Wu ◽

Yuqing He ◽

Xingyuan Liu ◽

Mingqian Liu ◽

...

Keyword(s):

Risk Factors ◽

Retrospective Study ◽

Age Groups ◽

Clinical Manifestations ◽

Population Based ◽

Male Gender ◽

Poor Correlation ◽

Age Related ◽

Related Risk ◽

Independent Risk Factors

Objective: To study the differences in clinical characteristics, risk factors, and complications across age-groups among the inpatients with the coronavirus disease 2019 (COVID-19).Methods: In this population-based retrospective study, we included all the positive hospitalized patients with COVID-19 at Wuhan City from December 29, 2019 to April 15, 2020, during the first pandemic wave. Multivariate logistic regression analyses were used to explore the risk factors for death from COVID-19. Canonical correlation analysis (CCA) was performed to study the associations between comorbidities and complications.Results: There are 36,358 patients in the final cohort, of whom 2,492 (6.85%) died. Greater age (odds ration [OR] = 1.061 [95% CI 1.057–1.065], p < 0.001), male gender (OR = 1.726 [95% CI 1.582–1.885], p < 0.001), alcohol consumption (OR = 1.558 [95% CI 1.355–1.786], p < 0.001), smoking (OR = 1.326 [95% CI 1.055–1.652], p = 0.014), hypertension (OR = 1.175 [95% CI 1.067–1.293], p = 0.001), diabetes (OR = 1.258 [95% CI 1.118–1.413], p < 0.001), cancer (OR = 1.86 [95% CI 1.507–2.279], p < 0.001), chronic kidney disease (CKD) (OR = 1.745 [95% CI 1.427–2.12], p < 0.001), and intracerebral hemorrhage (ICH) (OR = 1.96 [95% CI 1.323–2.846], p = 0.001) were independent risk factors for death from COVID-19. Patients aged 40–80 years make up the majority of the whole patients, and them had similar risk factors with the whole patients. For patients aged <40 years, only cancer (OR = 17.112 [95% CI 6.264–39.73], p < 0.001) and ICH (OR = 31.538 [95% CI 5.213–158.787], p < 0.001) were significantly associated with higher odds of death. For patients aged >80 years, only age (OR = 1.033 [95% CI 1.008–1.059], p = 0.01) and male gender (OR = 1.585 [95% CI 1.301–1.933], p < 0.001) were associated with higher odds of death. The incidence of most complications increases with age, but arrhythmias, gastrointestinal bleeding, and sepsis were more common in younger deceased patients with COVID-19, with only arrhythmia reaching statistical difference (p = 0.039). We found a relatively poor correlation between preexisting risk factors and complications.Conclusions: Coronavirus disease 2019 are disproportionally affected by age for its clinical manifestations, risk factors, complications, and outcomes. Prior complications have little effect on the incidence of extrapulmonary complications.

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Characteristics of mortality in the Orenburg region population in 2011-2017

Science and Innovations in Medicine ◽

10.35693/2500-1388-2020-5-2-99-104 ◽

2020 ◽

Vol 5 (2) ◽

pp. 99-104

Author(s):

Evgenii L. Borschuk ◽

Dmitrii N. Begun ◽

Tatyana V. Begun

Keyword(s):

Mortality Rate ◽

Causes Of Death ◽

Age Groups ◽

Circulatory System ◽

Mortality Rates ◽

Female Population ◽

Orenburg Region ◽

The Third ◽

Circulatory System Diseases ◽

External Causes

Objectives - to study the mortality indicators, their dynamics and structure, in the population of the Orenburg region in the period of 2011-2017. Material and methods. The study was conducted using the data from the territorial authority of statistics in the Orenburg region in the period from 2011 to 2017. The analytical, demographic and statistical methods were implemented for the study of the demographic indicators. Results. Cities and municipal settlements of the Orenburg region with high mortality indicators were included in the second and fourth clusters during the cluster analysis. The first and third clusters included cities and municipal settlements with an average mortality. The most favorable position has the Orenburg area with the lowest mortality rate in the region in 2017 - 8.4%. The dynamics of mortality rates among the male and female population tends to decrease, more pronounced dynamics is in men. Though, the male population is characterized by higher mortality rates in all age groups. The leading position among the causes of death is taken by diseases of the circulatory system (46.3% of the total mortality). The second position is occupied by tumors (17.2%), the third - by external causes (8.4%). Mortality from circulatory system diseases and from external causes has reduced. The dynamics of mortality from tumors does not change significantly. The rank of leading causes of death is not identical in the clusters: in the third and fourth clusters, the other causes occupy the second place in the structure of mortality, while tumors occupy the third. Conclusion. In the Orenburg region, the mortality rate is higher than overage in the Russian Federation by 0.9 per 1000 people. The study revealed significant territorial differences in the mortality rates. In general, the mortality among men in all age groups is higher than the mortality of women. The mortality rate from diseases of the circulatory system plays the leading role in the structure of mortality, but has the tendency for decline. Until 2006, the mortality from external causes ranked the second place, now the second place is taken by death from tumors The mortality from external causes is decreasing; mortality from tumors does not change significantly. The obtained results could be used by local authorities in developing the program of public health protection and assessing its effectiveness.

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Mortality, causes of death and influence of medication use in patients with systemic lupus erythematosus vs matched controls

Rheumatology ◽

10.1093/rheumatology/keaa267 ◽

2020 ◽

Vol 60 (1) ◽

pp. 207-216

Author(s):

Irene E M Bultink ◽

Frank de Vries ◽

Ronald F van Vollenhoven ◽

Arief Lalmohamed

Keyword(s):

Mortality Rate ◽

Lupus Erythematosus ◽

Mortality Rates ◽

Cox Proportional Hazards ◽

Practice Research ◽

Clinical Practice Research Datalink ◽

Risk Of Mortality ◽

Increased Risk ◽

Specific Mortality ◽

Age And Sex

Abstract Objectives We wanted to estimate the magnitude of the risk from all-cause, cause-specific and sex-specific mortality in patients with SLE and relative risks compared with matched controls and to evaluate the influence of exposure to medication on risk of mortality in SLE. Methods We conducted a population-based cohort study using the Clinical Practice Research Datalink, Hospital Episode Statistics and national death certificates (from 1987 to 2012). Each SLE patient (n = 4343) was matched with up to six controls (n = 21 780) by age and sex. Cox proportional hazards models were used to estimate overall and cause-specific mortality rate ratios. Results Patients with SLE had a 1.8-fold increased mortality rate for all-cause mortality compared with age- and sex-matched subjects [adjusted hazard ratio (HR) = 1.80, 95% CI: 1.57, 2.08]. The HR was highest in patients aged 18–39 years (adjusted HR = 4.87, 95% CI: 1.93, 12.3). Mortality rates were not significantly different between male and female patients. Cumulative glucocorticoid use raised the mortality rate, whereas the HR was reduced by 45% with cumulative low-dose HCQ use. Patients with SLE had increased cause-specific mortality rates for cardiovascular disease, infections, non-infectious respiratory disease and for death attributable to accidents or suicide, whereas the mortality rate for cancer was reduced in comparison to controls. Conclusion British patients with SLE had a 1.8-fold increased mortality rate compared with the general population. Glucocorticoid use and being diagnosed at a younger age were associated with an increased risk of mortality. HCQ use significantly reduced the mortality rate, but this association was found only in the lowest cumulative dosage exposure group.

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Lamb mortality in a flock of East African Blackheaded sheep

The Journal of Agricultural Science ◽

10.1017/s0021859600060330 ◽

1966 ◽

Vol 66 (1) ◽

pp. 97-100 ◽

Cited By ~ 2

Author(s):

J. C. M. Trail ◽

G. D. Sacker

Keyword(s):

Birth Weight ◽

Mortality Rate ◽

Mortality Rates ◽

Dry Season ◽

East African ◽

Male And Female ◽

The Mean ◽

Overall Mortality

1. The effects of birth weight, sex, twinning, parity of dam and dry season on mortality rates of lambs were studied between birth and weaning at 20 weeks in a flock of East African Blackheaded sheep.2. The mean birth weights of non-surviving lambs were lower than those of surviving lambs. Singles from gimmers and twins from ewes were 0.5 and 1.0 lb., respectively, lighter at birth, and had higher mortality rates than singles from ewes. The overall mortality rate of singles from ewes was 16%, singles from gimmers 20% and twins from ewes 28%. Male and female lambs born alive had similar mortality rates (18%).

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