scholarly journals Morphological types of constitution in persons with clinical symptoms of lumbar osteochondrosis

1998 ◽  
Vol XXX (1-2) ◽  
pp. 63-64
Author(s):  
L. A. Kadyrovа ◽  
N. N. Sak ◽  
V. G. Marchenko ◽  
O. I. Gelevey ◽  
А. V. Nosatov ◽  
...  
Keyword(s):  
Nervous System ◽  
Clinical Symptoms ◽  
Examination System ◽  
Body Morphology ◽  
Constitutional Type

One of the promising directions in the search for regularities in the course and, consequently, treatment of vertebrogenic diseases of the nervous system (VNS) is an orientation towards integrative principles of diagnosis based on taking into account the constitutional type of a person and constitutionally determined features of his psyche, physiology and body morphology. Constitutional diagnostics is based precisely on these three whales identified by Claudius Galen. The introduction of constitutional diagnostics into the patient examination system immediately introduces a certain order into the medical strategy and tactics.

ULTRASONIC STUDY IN DIAGNOSTICS OF PERIPHERAL NEUROPATHIES (CASE FROM PRACTICE)

2021 ◽  
pp. 144-146
Author(s):  
Hamanovich A.I. ◽  
◽  
Baida A.G. ◽  
Koyalo L.G. ◽  
Levantsevich V.V. ◽  
...  
Keyword(s):  
Nervous System ◽  
Gold Standard ◽  
Peripheral Nerves ◽  
Peroneal Nerve ◽  
Clinical Case ◽  
Clinical Symptoms ◽  
Nerve Trunk ◽  
Peripheral Neuropathies ◽  
Ultrasound Scanning ◽  
Electrophysiological Methods

Electrophysiological methods, such as electromyography and neuromyography, are traditionally recognized as the "gold standard" for detecting pathology of the peripheral nervous system. It should be noted, however, that the information obtained during the above examinations does not give an idea of the state of the surrounding tissues, does not indicate the nature and cause of damage to the nerve trunk, and does not always accurately reflect the localization of changes. At the same time, it is this information that helps to determine the tactics of conservative or surgical treatment of the patient. Ultrasound scanning is quite successfully used in the diagnosis of damage and diseases of the peripheral nerves. The article presents a clinical case of a diagnostic search for a causative disease in a patient with clinical symptoms of neuropathy of the peroneal nerve.

Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review

Neurosurgery ◽  
2015 ◽  
Vol 78 (3) ◽  
pp. 343-352 ◽  
Author(s):  
Arnault Tauziede-Espariat ◽  
Andre Maues de Paula ◽  
Melanie Pages ◽  
Annie Laquerriere ◽  
Emilie Caietta ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Overall Survival ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Clinical Symptoms ◽  
Malignant Gliomas ◽  
Leptomeningeal Gliomatosis ◽  
Molecular Features ◽  
The Central Nervous System ◽  
The Mean

Abstract BACKGROUND: Primary leptomeningeal gliomatosis (PLG) is a poorly recognized tumor of the central nervous system. OBJECTIVE: To describe the histopathological, immunohistochemical, and molecular features of PLG. METHODS: Results of our multicentric retrospective study of 6 PLG cases (3 pediatric and 3 adult) were compared with literature data. RESULTS: The mean age was 54.7 years for adults and 8.7 years for children, with 3 males and 3 females. Clinical symptoms were nonspecific. Cerebrospinal fluid analyses showed a high protein level often associated with pleocytosis but without neoplastic cells. On neuroimaging, diffuse leptomeningeal enhancement and hydrocephalus were observed, except in 1 case. PLG was mostly misinterpreted as infectious or tumoral meningitis. The first biopsy was negative in 50% of cases. Histopathologically, PLG cases corresponded to 1 oligodendroglioma without 1p19q codeletion and 5 astrocytomas without expression of p53. No immunostaining for IDH1R132H and no mutations of IDH1/2 and H3F3A genes were found. Overall survival was highly variable (2-82 months) but seems to be increased in children treated with chemotherapy. CONCLUSION: This study shows the difficulties of PLG diagnosis. The challenge is to achieve an early biopsy to establish a diagnosis and to begin a treatment, but the prognosis remains poor. PLG seems to have a different molecular and immunohistochemical pattern compared with intraparenchymal malignant gliomas.

scholarly journals Variable Presentations in Pulmonary Arteriovenous Malformation

2020 ◽  
Vol 8 (2) ◽  
pp. 1-8
Author(s):  
Nasir Ahmad Lone ◽  
Akshit Kumar ◽  
Waseem Ahmed Sheikh
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Clinical Symptoms ◽  
Case Series ◽  
Neurological Complications ◽  
Pulmonary Arteriovenous Malformations ◽  
Exertional Dyspnea ◽  
Paradoxical Emboli

Pulmonary arteriovenous malformations (PAVM) are a group of vascular anomalies of lung which present with variable clinical symptoms. Most patients with PAVM are asymptomatic but it can cause dyspnea on exertion, paradoxical emboli to brain causing various central nervous system complications like stroke and brain abscess, hemoptysis and rupture. The age at the presentation can range from 1st to 7th decade but the majority of patients present before the age of 30 years. PAVM is strongly associated with hereditary haemorrhagic telangiectasis which presents with epistaxis, mucocutaneous telangiectasias and AV malformations of various organs. In our case series, we have patients ranging from 3 yrs to 75 years with presentation ranging from asymptomatic to exertional dyspnea, hemoptysis and neurological complications.

Acute Health Effects of Pesticide Exposure among Farmers Directly Involved with Spraying: A Cross-Sectional Pilot Study from Kashmir Valley

2021 ◽  
Vol 11 (5) ◽  
pp. 169-177
Author(s):  
Sobia Nisar ◽  
Umar Muzaffer ◽  
Ozaifa Kareem
Keyword(s):  
Nervous System ◽  
Health Effects ◽  
Respiratory Symptoms ◽  
Pesticide Exposure ◽  
Clinical Symptoms ◽  
Psychological Symptoms ◽  
Neurological Complications ◽  
Agricultural Workers ◽  
Cross Sectional ◽  
Study Population

Background: Organophosphates (OP) are the extensively used pesticides that protect the agricultural produce from being damaged by the pests. These inhibit the acetylcholinesterase enzyme activity acutely which has a key role in the normal physiological functioning of the nervous system. There is an imminent possibility of deterioration of health in agricultural workers at the risk of OP exposure. The aim of this study was to analyze the clinical symptoms and chronic health effects of OP exposure among agricultural workers associated with spraying of pesticides in Kashmir, India. Methods: This cross-sectional study was undertaken among agricultural workers associated with pesticide spraying at least once a year. A questionnaire based survey and clinical examination was conducted among study participants. The specific questions regarding the occupational history, pattern of spraying, history and symptoms of OP pesticide exposure were noted. The use of personal protective equipment, number of years of OP exposure and the volume of pesticide used were also noted. Biochemical evaluation and serum acetylcholinesterase levels were measured by standard protocol. Results: A total of 63 subjects participated in the study with n= 61 (96.8%) males and n= 2 (3.2%) females. The study population had a mean age of 40.90 ± 12.66 years. Our results show considerable association between OP exposure and various neurological, psychological, mucoskeletal and respiratory symptoms, but it was not enough to provide evidence of biochemical derangement. The neurological symptoms included weakness (60.3%), dizziness (44.4%), headache (38.09%), fatigue (30.1%), and muscle pain (19.04%). The psychological symptoms included low mood (66.6%), anhedonia (46.03%), insomnia (23.8%), anxiety (19.04%), and nervousness (11.1%).Among respiratory symptoms cough (58.7%) was most commonly reported followed by cough with phlegm (41.2%) and breathlessness (12.6%). Only 9.5% of the study population reported the immediate symptom onset while 33.3% of participants reported delayed onset. Conclusion: The neurological complications were most commonly reported followed by ophthalmological symptoms. We concluded that OP exposure affects the nervous system followed by musculoskeletal, integumentary and respiratory systems with least impact on cardiovascular system. Key words: organophosphorus; acetylcholinesterase; neurological; farm workers; occupational exposure; pesticides.

COVID-19 Beyond the Lungs

2022 ◽  
pp. 109-126
Author(s):  
Omar El Hiba ◽  
Hicham Chatoui ◽  
Nadia Zouhairi ◽  
Lahoucine Bahi ◽  
Lhoussaine Ammouta ◽  
...  
Keyword(s):  
Experimental Data ◽  
Nervous System ◽  
Clinical Symptoms ◽  
Case Reports ◽  
The World ◽  
Acute Pneumonia ◽  
The Brain ◽  
Cardinal Feature ◽  
Shed Light

Since December 2019, the world has been shaken by the spread of a highly pathogen virus, causing severe acute respiratory syndrome (SARS-Cov2), which emerged in Wuhan, China. SARS-Cov2 is known to cause acute pneumonia: the cardinal feature of coronavirus disease 2019 (COVID-19). Clinical features of the disease include respiratory distress, loss of spontaneous breathing, and sometimes neurologic signs such as headache and nausea and anosmia, leading to suppose a possible involvement of the nervous system as a potential target of SARS-CoV2. The chapter will shed light on the recent clinical and experimental data sustaining the involvement of the nervous system in the pathophysiology of COVID-19, based on several case reports and experimental data reporting the possible transmission of SARS-CoV2 throughout the peripheral nerves to the brain cardiorespiratory centers. Thus, understanding the role of the nervous system in the course of clinical symptoms of COVID-19 is important in determining the appropriate therapeutic approach to combat the disease.

Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome

2008 ◽  
Vol 509 (6) ◽  
pp. 642-660 ◽  
Author(s):  
Hendrik Luuk ◽  
Sulev Koks ◽  
Mario Plaas ◽  
Jens Hannibal ◽  
Jens F. Rehfeld ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Symptoms ◽  
Wolfram Syndrome ◽  
The Central Nervous System

Mucopolysaccharidosis in Adults

2016 ◽  
Author(s):  
Christian J. Hendriksz ◽  
Francois Karstens
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Autosomal Recessive ◽  
Clinical Symptoms ◽  
Cell Types ◽  
Type Ii ◽  
System P ◽  
Different Types ◽  
The Central Nervous System ◽  
Different Cell Types

There are 8 different types of diseases of the mucopolysaccharides, each caused by a deficiency in one of 10 different enzymes involved in the degradation of glycosaminoglycans (GAGs). Partially degraded GAGs accumulate within the lysosomes of many different cell types and lead to clinical symptoms and excretion of large amounts of GAGs in the urine. Heritability is autosomal recessive except for MPS type II, which is X-linked. The disorders are chronic and progressive and, although the specific types all have their individual features, they share an abundance of clinical similarities. All involve the musculoskeletal, the cardiovascular, the pulmonary and the central nervous system.

scholarly journals Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Bayan Al Share ◽  
Ali Zakaria ◽  
Evan Hiner ◽  
Ziyad Iskenderian ◽  
Nader Warra
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Symptoms ◽  
Wide Spectrum ◽  
Imaging Techniques ◽  
Systemic Vasculitis ◽  
Comfort Care ◽  
Systemic Involvement ◽  
Primary Angiitis ◽  
The Central Nervous System

Primary angiitis of the central nervous system (PACNS) is a rare vasculitis involving medium and small blood vessels of the brain, spinal cord, and meninges, without systemic involvement. The diffuse and patchy nature of its pathology is reflected by a wide spectrum of nonspecific clinical symptoms. Diagnosis is challenging due to lack of defined clinical criteria or specific imaging findings. Specific workup should be done only after exclusion of other etiologies, including infectious, neoplastic, toxic, and other vascular etiologies including systemic vasculitis. Given the fact that it is a patchy disease with 25% of the biopsies being falsely negative, treating physician should have a high index of suspicion despite negative initial neurovascular imaging and biopsy results. Once diagnosed, early treatment with immunosuppressive therapy is essential to avoid permanent neurologic damage. Herein, we are reporting a case of 66-year-old female patient who presented with insidious onset right-sided frontal headache. Her hospital course progressively worsened and family decision based on her wishes was to refer her to hospice and comfort care. Despite an extensive workup with advanced imaging techniques, no diagnosis was established until postmortem autopsy and histopathology confirmed primary angiitis of the central nervous system.

scholarly journals Diabetic cervicobrachial radiculoplexopathy

2019 ◽  
Vol 11 (4) ◽  
pp. 160-165
Author(s):  
L. T. Akhmedzhanova ◽  
A. I. Isaikin ◽  
O. A. Chernenko ◽  
Yu. M. Shor ◽  
D. M. Merkulova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Clinical Features ◽  
Lipoic Acid ◽  
Clinical Case ◽  
Clinical Symptoms ◽  
Alpha Lipoic Acid ◽  
First Time ◽  
Damage Types

Peripheral nervous system (PNS) damage is one of the most common complications of diabetes mellitus. There may be different PNS damage types that differ in clinical symptoms and pathogenesis. A clinical case of diabetic cervicobrachial radiculoplexopathy is presented for the first time in Russia. The paper discusses the clinical features of this type versus diabetic lumbosacral radiculoplexopathy, instrumental diagnosis of diabetic radiculoplexopathies, pathogenetic mechanisms of the disease, and treatment approaches. It shows the efficacy of alpha-lipoic acid supplementation in a patient with diabetic radiculoplexopathy.

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