scholarly journals Advantages and disadvantages of lockdown (self-isolation regime) introduced during the first wave of coronaviral infection for patients with polymorbid pathology

2021 ◽  
Vol 29 (3) ◽  
pp. 364-368
Author(s):  
Nailya S. Asfandiyarova ◽  
Evgenii V. Filippov ◽  
Ol'ga V. Dashkevich ◽  
Natalia V. Doroshina ◽  
Ekaterina I. Suchkova ◽  
...  
Keyword(s):  
Physical Activity ◽  
Nervous System ◽  
Cardiovascular Diseases ◽  
Causes Of Death ◽  
Preventive Measures ◽  
Nervous System Diseases ◽  
Advantages And Disadvantages ◽  
Oncological Diseases ◽  
Coronavirus Infection ◽  
Overall Mortality

AIM: To study the structure of mortality not caused by coronavirus infection, in patients with polymorbid pathology during the period of self-isolation (lockdown). MATERIALS AND METHODS: Outpatient records of 2 423 patients with polymorbid pathology (841 males and 1 582 females, aged from 18 to 99 years) were examined. The mortality and its causes during three years including a period of lockdown were investigated. RESULTS: The overall mortality rate among patients with polymorbid pathology was 10.2% without differences in gender. The structure of the causes of death in patients with polymorbidity: cardiovascular diseases accounted for 50.8%, oncological diseases 21%, nervous system diseases 7.3%. During the lockdown, an increase in overall mortality by 34.3% was recorded (p 0.05), with an increase in the number of deaths of patients with cardiovascular diseases by 19.5% (p 0.05) (mostly patients with ischemic heart disease). CONCLUSION: An increase in the number of deceased patients with polymorbidity during the lockdown may be due to the limitation of physical activity, of the possibility of examination and consultation by profile specialists. Taking into account the vulnerability of this group of patients, there is an urgent need to develop preventive measures when the situation recurs.

scholarly journals Mortality of Lithuanian Population Over 2 Decades of Independence: Critical Points and Contribution of Major Causes of Death

Medicina ◽  
2013 ◽  
Vol 49 (1) ◽  
pp. 7 ◽  
Author(s):  
Ramunė Kalėdienė ◽  
Skirmantė Sauliūnė
Keyword(s):  
Cardiovascular Diseases ◽  
Causes Of Death ◽  
Significant Contribution ◽  
Positive Health ◽  
Cut Points ◽  
Best Fitting ◽  
Males And Females ◽  
External Causes ◽  
Sustainable Health ◽  
Overall Mortality

The aim of the study was to analyze trends in overall mortality and mortality from major causes of death, detect differences in cut points, and estimate the contribution of the major causes of death to the changes in overall mortality throughout 2 decades of independence in Lithuania (1991–2000 and 2001–2010). Material and Methods. Overall mortality and mortality from cardiovascular diseases, cancer, and external causes were analyzed for the periods of 1991–2000 and 2001–2010. Joinpoint analysis was used to identify the best-fitting points wherever a statistically significant change in mortality occurred, and analysis of components was applied for the assessment of the contribution of major causes of death. Results. The 1991–1994 period was identified as the most negative in terms of increasing mortality from all major causes of death, while the 2007–2010 period was most favorable, when the most significant decline in overall mortality was observed (4.84% per year for males and 4.41% per year for females). External causes contributed most to the growing overall mortality in 1991–1994 both for males and females (37.20% and 25.29%, respectively). Since 2007, all major causes contributed positively to the declining overall mortality of the Lithuanian population. The most significant contribution was made by cardiovascular diseases and external causes. Conclusions. Despite the considerable transformations of socioeconomic situation and economic crisis, it is likely that Lithuania is entering into the stage of positive health development. For assuring this trend in the future, investments in sustainable health and social developments are inevitable.

scholarly journals Dynamics of the factors cardiovascular diseases depending on a dispensary observation status in the regional polyclinic of Krasnodar, 2015-2018

2021 ◽  
Vol 2 (2) ◽  
pp. 62-69
Author(s):  
E. V. Bolotova ◽  
I. V. Kovrigina
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Cardiovascular Diseases ◽  
Preventive Measures ◽  
Overweight And Obesity ◽  
Observation Group ◽  
Medical Organization ◽  
Target Values ◽  
The Status ◽  
Unhealthy Diet

Objective: to study the dynamics of risk factors for cardiovascular diseases in patients who are under dispensary observation for the main disease arterial hypertension and coronary heart disease; the frequency of visits to a medical organization, depending on the status of dispensary observation in a cohort of adults in 2015 and 2018. Materials and Methods: on the basis of the outpatient department of the Scientific Research Institute – Krasnodar Regional Hospital No. 1, we analyzed the incidence of CVD in the adult cohort (n = 1170), which passed of the clinical examination twice in 2015 and 2018. The analysis was carried out in groups depending on the status of the dispensary observation («not on dispensary observation», «total on dispensary observation» and «consisting on dispensary observation with CVD»). Results: a decrease in unhealthy diet by 32.21%, 28.78% and 28%, respectively, was shown in the groups «not on dispensary observation», «total on dispensary observation» and «consisting on dispensary observation with CVD» in 2015 and 2018, (χ2 = 80.45, p = 0.001, χ2 = 59.96, p = 0.001 and χ2 = 47.8; p = 0.001). In the groups «not on dispensary observation», «total on dispensary observation» and «consisting on dispensary observation with CVD» in 2015 and 2018, there was a decrease in low physical activity by 50.33%, 24.72% and 21.85%, respectively (χ2 = 79.16, p = 0.001, χ2 = 30.6, p = 0.001 and χ2 = 22.42; p = 0.001). Against the background of the ongoing preventive measures in 2015 – 2018. the cohort showed an increase in overweight and obesity by 19.2% in the «not on dispensary observation» group (χ2 = 4.84, p = 0.028); an increase in the frequency of elevated blood pressure by 48.33% in the «not on dispensary observation» group and a decrease in its frequency in the «consisting on dispensary observation with CVD» by 24% (χ2 = 19.77, p = 0.001, χ2 = 7.1; p = 0.008). Against the background of the ongoing preventive measures from 2015 to 2018, a tendency to reduce the frequency of FR CVD was revealed. A significant decrease in unhealthy diet (p = 0.001), low physical activity (p = 0.001), was registered in individuals who were on dispensary observation according to the main nosology of hypertension. In the group of individuals who were on dispensary observation according to the main nosology, there was a significant decrease in unhealthy diet (p = 0.006) and low physical activity (p = 0.023). In patients who are on dispensary observation with CVD, there was a favorable dynamics in terms of achieving the target values of the level of blood pressure and cholesterol. The revealed tendency to decrease the frequency of visits due to CVD in patients «consisting on dispensary observation» by 32.2%, including» consisting on dispensary observation with CVD» by 33.8% for the period 2015 – 2018. Conclusions: there was a tendency to decrease the frequency of risk factor CVD and the frequency of visits due to CVD in patients «consisting on dispensary observation», which indicates the effectiveness of measures carried out within the observation, regardless of the nosological group of patients.

scholarly journals Pandemic of Fear or What Statistics Hide: Patients with Cardiovascular Disease are at Increased Risk During COVID-19

2021 ◽  
Vol 21 ◽  
Author(s):  
Oleg Gaisenok
Keyword(s):  
Cardiovascular Disease ◽  
Acute Coronary Syndrome ◽  
Cardiovascular Diseases ◽  
Causes Of Death ◽  
Hospitalization Rate ◽  
Statistical Information ◽  
Coronary Syndrome ◽  
Increased Risk ◽  
International Data ◽  
Coronavirus Infection

Insufficient statistical information on the structure of mortality in the era of the pandemic is disclosed in this article. It analyzes the statistics and the causes of death during the COVID-19 pandemic from a new coronavirus infection and cardiovascular disease. Actual international data on a decrease in the hospitalization rate of patients with acute coronary syndrome are presented. A comparative analysis of statistics from European countries and Russia shows that cardiovascular diseases are the leading cause of death in populations, and patients with cardiovascular diseases are at increased risk for morbidity and mortality during the COVID pandemic.

scholarly journals Changes in diabetes mortality in Sasovo district of Ryazan region during 2003—2013 years

2015 ◽  
Vol 61 (6) ◽  
pp. 17-22 ◽  
Author(s):  
Nailya Sayfullaevna Asfandiyarova ◽  
Aleksey Aleksandrovich Nizov ◽  
Tat'yana Davydovna Zdol'nik ◽  
Irina Viktorovna Shatrova ◽  
Aleksey Anatol'evich Budylin
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factor ◽  
Causes Of Death ◽  
Preventive Measures ◽  
Total Mortality ◽  
Diabetic Patients ◽  
Diabetes Mortality ◽  
Patients With Diabetes ◽  
Overall Mortality ◽  
Cvd Mortality

Aim.To study the overall mortality, mortality from cardiovascular diseases and cancer (CVD, C) in patients with diabetes mellitus (DM) in Sasovo District of Ryazan Region during 2003—2013 years.Material and Methods.We studied the diabetes overall mortality, CVD and cancer mortality dynamics in Sasovo District of Ryazan region during 2003—2013 years. In 2003, the population of the district was 52 100 people, in 2013 — 45 316. In 2003 years, it was registered 550 patients with diabetes, in 2013 years — 736.The coefficients of overall mortality, mortality from diseases were calculated according to standard formulas per 1000 population.Results.It was revealed the reduction of total and cardiovascular mortality in the population (p<0,001) during period of observation. There is a trend towards reduction in total mortality and mortality from CVD in diabetic patients (p>0,05), but it is in 2—3,4 times higher than among the population The main causes of death in diabetic patients are CVD (67.8%) and cancer (10.9%), the dynamics of these figures were not observed.Conclusions.CVD and cancer are the leading cause of death in diabetes. Absence of changes in the level of CVD mortality, suggests the need for preventive measures for influence on this risk factor.

scholarly journals Advances in intranasal application of stem cells in the treatment of central nervous system diseases

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yu-Ting Zhang ◽  
Kai-Jie He ◽  
Jin-Bao Zhang ◽  
Quan-Hong Ma ◽  
Fen Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Cell Types ◽  
Nervous System Diseases ◽  
Central Nervous System Diseases ◽  
Advantages And Disadvantages

AbstractStem cells are characterized by their self-renewal and multipotency and have great potential in the therapy of various disorders. However, the blood–brain barrier (BBB) limits the application of stem cells in the therapy of neurological disorders, especially in a noninvasive way. It has been shown that small molecular substances, macromolecular proteins, and even stem cells can bypass the BBB and reach the brain parenchyma following intranasal administration. Here, we review the possible brain-entry routes of transnasal treatment, the cell types, and diseases involved in intranasal stem cell therapy, and discuss its advantages and disadvantages in the treatment of central nervous system diseases, to provide a reference for the application of intranasal stem cell therapy.

scholarly journals THE MEDITERRANEAN DIET IN THE PREVENTION OF CARDIOVASCULAR AND NERVOUS SYSTEM DISEASES – THE ASSESSMENT OF NUTRITIONAL KNOWLEDGE

2020 ◽  
Vol 73 (7) ◽  
pp. 1448-1453
Author(s):  
Kamila Wachuła ◽  
Joanna Furman ◽  
Beata Łabuz-Roszak
Keyword(s):  
Nervous System ◽  
Cardiovascular Diseases ◽  
Neurodegenerative Diseases ◽  
Mediterranean Diet ◽  
Public Knowledge ◽  
Nervous System Diseases ◽  
Nutritional Knowledge ◽  
Study Results ◽  
Level Of Knowledge ◽  
The Mediterranean

Introduction: Following a Mediterranean diet significantly reduces the risk of cardiovascular and neurodegenerative diseases. The aim of the study was to assess nutritional knowledge among adult residents of the Silesian Province on the Mediterranean diet in the prevention of cardiovascular and nervous system diseases. Material and methods: The study was conducted using an anonymous self-made questionnaire. 190 adults from the Silesian Province participated in the study. Results: The respondents had a good or sufficient level of knowledge on the Mediterranean diet. Respondents as the benefits of using the Mediterranean diet more often indicated a reduction in the risk of cardiovascular diseases than prevention of nervous system diseases. Conclusions: The inhabitants of Silesian Province have a fairly good level of knowledge on the preventive use of the Mediterranean diet. Public knowledge on the prevention of cardiovascular diseases, as well as knowledge on the principles of the Mediterranean diet, and on the benefits of its use, can reduce the incidence of cardiovascular and nervous system diseases.

MORBIDITY AND PREVALENCE OF THE NERVOUS SYSTEM DISEASES IN CHILDREN OF UKRAINE

2020 ◽  
Vol 16 (73) ◽  
pp. 032
Author(s):  
O.P. Volosovets ◽  
T.O. Kryuchko ◽  
S.P. Kryvopustov ◽  
М.О. Gonchar ◽  
A.O. Volosovets ◽  
...  
Keyword(s):  
Nervous System ◽  
Nervous System Diseases

ROLE OF THE CENTERS OF THE CENTRAL AND INDEPENDENT CONTOURS IN REGULATION OF THE INTIMATE RHYTHM AT PERFORMANCE OF STANDARD PHYSICAL ACTIVITY

ASJ. ◽  
2020 ◽  
Vol 2 (40) ◽  
pp. 22-31
Author(s):  
A.B. Shutov ◽  
A.A. Matskanjuk ◽  
C. V. Korney
Keyword(s):  
Physical Activity ◽  
Nervous System ◽  
Analysis Time ◽  
Vegetative Nervous System ◽  
Distinctive Features

Use of a method of share tendencies in the analysis time of some R-R intervals of the electrocardiogram after performance of 20 knee-bends and after 1 minute of restoration has allowed to establish a role of the centers of vegetative nervous system in restoration of a rhythm of heart at 4-th level of dynamic hierarchy. After 20-ти knee-bends and through 1 minutes of restoration the maximum vegetative centers of the central contour dominate. In interaction of the central and independent contours each center entering into them is characterized with distinctive features of dynamics which are shown in an increasing role of the centers of an independent contour after 1 minute of restoration.

scholarly journals Systematic review of international clinical guidelines for the promotion of physical activity for the primary prevention of cardiovascular diseases

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
N. Aerts ◽  
D. Le Goff ◽  
M. Odorico ◽  
J. Y. Le Reste ◽  
P. Van Bogaert ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Clinical Practice ◽  
Cardiovascular Diseases ◽  
Primary Prevention ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Clinical Guidelines ◽  
Prevention Programs ◽  
Prevention Of Cardiovascular Disease

Abstract Background Cardiovascular diseases are the world’s leading cause of morbidity and mortality. An active lifestyle is one of the cornerstones in the primary prevention of cardiovascular disease. An initial step in guiding primary prevention programs is to refer to clinical guidelines. We aimed to systematically review clinical practice guidelines on primary prevention of cardiovascular disease and their recommendations regarding physical activity. Methods We systematically searched Trip Medical Database, PubMed and Guidelines International Network from January 2012 up to December 2020 using the following search strings: ‘cardiovascular disease’, ‘prevention’, combined with specific cardiovascular disease risk factors. The identified records were screened for relevance and content. We methodologically assessed the selected guidelines using the AGREE II tool. Recommendations were summarized using a consensus-developed extraction form. Results After screening, 27 clinical practice guidelines were included, all of which were developed in Western countries and showed consistent rigor of development. Guidelines were consistent about the benefit of regular, moderate-intensity, aerobic physical activity. However, recommendations on strategies to achieve and sustain behavior change varied. Multicomponent interventions, comprising education, counseling and self-management support, are recommended to be delivered by various providers in primary health care or community settings. Guidelines advise to embed patient-centered care and behavioral change techniques in prevention programs. Conclusions Current clinical practice guidelines recommend similar PA lifestyle advice and propose various delivery models to be considered in the design of such interventions. Guidelines identify a gap in evidence on the implementation of these recommendations into practice.

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