Genetic and Epigenetic Aspects of Obessity and Metabolic Syndrom in Child

2013 ◽  
Vol 4 (2) ◽  
pp. 3-11 ◽  
Author(s):  
Ludmila Viktorovna Tyrtova ◽  
Natalja Vladimirovna Parshina ◽  
Kristina Vladimirovna Skobeleva

In a review article analyzes the role of heredity in the occurrence of obesity and metabolic syndrome. Debut of hyperphagia and severe obesity from early childhood are typical for monogenic forms and syndromes. Many nonspecific candidate-genes in combination form a polygenic basis for the accumulation of excess body fat, especially under the influence of irrational diet and low physical activity. Examined the role of epigenetic factors in the individual genetic variants in fetus, predisposing to obesity and metabolic syndrome after birth. Discuss the possibilities of early prevention of obesity and metabolic syndrome.

Children ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 82
Author(s):  
Sara Lahuerta-Contell ◽  
Javier Molina-García ◽  
Ana Queralt ◽  
Vladimir E. Martínez-Bello

Research on physical activity (PA) in different educational settings could elucidate which interventions promote a healthy school lifestyle in early childhood education (ECE). The aims of this study were: (a) to analyse the PA levels of preschoolers during school hours, as well as the rate of compliance with specific recommendations on total PA (TPA) and moderate-vigorous PA (MVPA); (b) to examine the role of structured movement sessions and recess time in the MVPA levels during school hours; (c) to evaluate the sociodemographic correlates of preschoolers and the school environment on MVPA behaviour during school hours. PA was evaluated with Actigraph accelerometers. Our main findings were that: (a) preschoolers engaged in very little TPA and MVPA during school hours; (b) children showed significantly higher MVPA levels on days with versus without structured movement sessions, and the contribution of the structured sessions to MVPA was significantly higher than that of recess time; (c) gender and age were associated with PA, and a high density of young children on the playground was associated with high levels of vigorous PA, whereas in the classroom, high density was associated with more sedentary behaviour. Structured PA could reduce the gap in achieving international recommendations.


Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 161
Author(s):  
Paolo Custurone ◽  
Laura Macca ◽  
Lucrezia Bertino ◽  
Debora Di Mauro ◽  
Fabio Trimarchi ◽  
...  

The link between psoriasis and sport is a controversial issue. The topic has been poorly investigated, and nowadays there are many unsolved questions, dealing with the role of psoriasis in influencing the sporting habits of patients and, vice versa, the impact of sport activity on course, severity and extent of the disease, with particular regard to the indirect benefits on cardiovascular risk and metabolic syndrome. Moreover, the role of physical activity on patients’ quality of life and the potential limitations on physical activity due to joint involvement have not been well elucidated until now. In this narrative review we will try to provide answers to these queries.


SURG Journal ◽  
1969 ◽  
Vol 2 (2) ◽  
pp. 40-48 ◽  
Author(s):  
Mary-Ellen Wales

It is evident that convenience plays a prominent role in the food choices of today’s consumers. A trend having begun throughout the Western world, consumer demand for convenience foods is now on the rise around the globe. The growing presence of drive-thru windows, microwave dinners, take-out meals, home delivery for groceries and internet shopping, all demonstrate the importance of convenience in determining food choices. Costa et al. have argued that convenience itself determines where, when, why, what, how, and even with whom we eat. Several studies have examined the role that convenience plays in determining food choices, in particular, studies looking at the role of convenience in relation to full meal preparation and/ or consumption.The two areas of investigation will be 1) the dimensions of convenience as a part of the meal preparation and consumption processe, and 2) the individual characteristics of consumers and how they value these dimensions.


2010 ◽  
Vol 21 (12) ◽  
pp. 1894-1899 ◽  
Author(s):  
Eveline J. Wouters ◽  
Junilla K. Larsen ◽  
Hanna Zijlstra ◽  
Bert van Ramshorst ◽  
Rinie Geenen

2016 ◽  
Vol 13 (10) ◽  
pp. 1088-1093 ◽  
Author(s):  
Megan E. Holmes ◽  
Jim Pivarnik ◽  
Karin Pfeiffer ◽  
Kimberly S. Maier ◽  
Joey C. Eisenmann ◽  
...  

Background:The role of psychosocial stress in the development of obesity and metabolic syndrome is receiving increased attention and has led to examination of whether physical activity may moderate the stress-metabolic syndrome relationship. The current study examined relationships among physical activity, stress, and metabolic syndrome in adolescents.Methods:Participants (N = 126; 57 girls, 69 boys) were assessed for anthropometry, psychosocial stress, physical activity, and metabolic syndrome variables; t tests were used to examine sex differences, and regression analysis was used to assess relationships among variables controlling for sex and maturity status.Results:Mean body mass index approached the 75th percentile for both sexes. Typical sex differences were observed for systolic blood pressure, time spent in moderate and vigorous physical activity, and perceived stress. Although stress was not associated with MetS (β = –.001, P = .82), a modest, positive relationship was observed with BMI (β = .20, P = .04).Conclusions:Strong relationships between physical activity and stress with MetS or BMI were not found in this sample. Results may be partially explained by overall good physical health status of the participants. Additional research in groups exhibiting varying degrees of health is needed.


2019 ◽  
Vol 2 (2) ◽  
pp. 83
Author(s):  
Luh Ayu Purnami Dewi

<p><em>Childhood is a very important and valuable phase and is the period of formation in the period of human formation. Early childhood is often viewed as a golden age for education providers. The golden age of the child is a very fundamental phase for the development of the individual because in this phase there are great opportunities for the formation and development of a person. So great the role of parents in the formation of character and child development, it is natural if parents need to apply a balanced parenting (authoritative) in children, not authoritarian parenting or permissive.</em></p>


2018 ◽  
Vol 24 (15) ◽  
pp. 1711-1716 ◽  
Author(s):  
Elena V. Galitsyna ◽  
Andrey V. Zhelankin ◽  
Igor A. Sobenin ◽  
Alexander N. Orekhov

In addition to external factors, such as exercise, food and the environment, genetic predisposition makes great contribution to the development of metabolic disorders and cardiovascular disease. This review is aimed to examine the genetic basis of complex metabolic disorders conventionally described as "metabolic syndrome" (MetS), with the special focus on currently known mutations in the nuclear and mitochondrial genomes, which are associated with both the individual components of MetS and combinations thereof, and also on the studies of the relationship of MetS phenotype as a binary trait. The defects in the mitochondrial genome should be considered as one of the possible genetic reasons leading to MetS. It is known that mitochondrial dysfunction is closely associated with metabolic disorders, as mitochondria are the center of energy metabolism. Consequently, the changes in mitochondrial genes and their functions affect regulation of metabolism. Until now, the role of mitochondrial DNA damage in the development of cardiovascular diseases, age-related and metabolic disorders is still poorly understood. The results of performed studies would help assessing the role of mitochondrial DNA mutations in susceptibility to metabolic syndrome and related metabolic diseases.


Author(s):  
M. Rinaldi ◽  
G. Graffi ◽  
E. Rabino Massa

Metabolic Syndrome (MetS) is a cluster of conditions, each of which represents a risk factor for cardiovascular disease: central obesity, hyperglycemia, dyslipidemia and hypertension. Any of these conditions and MetS itself have been associated to Alzheimer's Disease and Vascular Dementia. In recent years there is a growing evidence for the role of physical activity in preventing metabolic diseases and cognitive decline. In our research we assessed the prevalence of MetS in a sample of 154 elderly people. Furthermore, we evaluated cognition (with Mini Mental State Examination, MMSE)  and the physical activity level in every patient. We found a significant association between MetS, borderline cognitive impairment and sedentary lifestyle.


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