scholarly journals Immunomodulating effect of magnetoinfrared laser therapy in children with chronic pyelonephritis

2019 ◽  
Vol 36 (1) ◽  
pp. 55-62
Author(s):  
Ya. Yu. Illek ◽  
M. L. Vyaznikova ◽  
N. P. Leushina ◽  
I. Yu. Mischenko ◽  
L. L. Ryseva ◽  
...  
Keyword(s):  
Blood Serum ◽  
Laser Therapy ◽  
Conventional Therapy ◽  
Therapy Group ◽  
Chronic Pyelonephritis ◽  
Complex Treatment ◽  
Immunological Reactivity ◽  
The Status ◽  
Group 2 ◽  
Group 1

Aim. To determine the influence of magnetoinfrared laser therapy on the status of immunological reactivity in children with chronic pyelonephritis (CP). Materials and methods. One hundred thirty children aged 8 to12 years, suffering from relapsing course of chronic pyelonephritis, were observed. Group 1 (43 patients) received complex conventional therapy, group 2 (27 patients) – complex treatment, associated with magnetoinfrared laser therapy. The blood lymphocyte population and subpopulation, blood serum immunoglobulin and circulating immune complexes content, phagocytosis indices, blood serum cytokine content was studied in children with chronic pyelonephritis at the active stage of disease, at the partial and full clinicolaboratory remission stages. Results. The CP patients of group 1, who received complex conventional therapy, demonstrated a full, but not long clinicolaboratpory remission with preservation of marked changes in immunological reactivity parameters. In CP patients of group 2, who experienced complex treatment associated with magnetoinfrared laser therapy courses, there occurred full clinicolaboratory remission and normalization of immunological reactivity indices. Conclusions. The results of clinical observations and special studies demonstrate high clinical, immunomodulating and antirelapsing effects of complex treatment combined with magnetoinfrared laser therapy in children with chronic pyelonephritis.

scholarly journals Dynamics of hormonal parameters in patients with climacteric syndrome in the context of hypothyroidism under the influence of complex therapy with Climact-Hel and Mulimen

2018 ◽  
Vol 22 (1) ◽  
pp. 203-207
Author(s):  
M. Pavlovska
Keyword(s):  
Normal Values ◽  
Therapy Group ◽  
Endocrine Disorders ◽  
Climacteric Syndrome ◽  
Complex Treatment ◽  
Complex Therapy ◽  
Before And After ◽  
Group 2 ◽  
Baseline Therapy ◽  
Group 1

In hypothyroidism, the climacteric syndrome has a tendency to an early start and a protracted course and manifests itself in the middle and severe forms with a predominance in the clinical picture of psychoemotional and metabolic-endocrine disorders. The purpose of the work is to compare the effectiveness of complex treatment of climacteric syndrome with concomitant hypothyroidism by analyzing hormonal indices before and after complex therapy using antihomotoxicological therapy. For its achievement, patients are divided into two groups: women who received only baseline therapy in accordance with the National Consensus on the management of patients in the climacteric diet (hereinafter — base therapy, group 1) and patients who, in addition to the baseline therapy, received therapy with antihomotoxic drugs (Group 2). After analyzing the patient's outcomes with the climacteric syndrome and concomitant hypothyroidism after the two treatment courses, there was a tendency for the IRI to decrease in both groups, but none of the groups was able to reach the normal level. Calcitriol increased in two observation groups, while in one group the index did not reach normal values. The decrease in the follicle stimulating hormone was observed in both groups and only the 1st group managed to get closer to normal values after two treatment cycles. The decrease in estradiol was observed in both groups of patients, but its significance was significantly lower in patients in the 1st group. Under the influence of treatment in accordance with the protocols in the first group, TTG significantly decreased, reaching the norm after the second course of treatment. In assessing the overall effectiveness of treatment, it turned out that with the use of baseline therapy, the effectiveness was 63.3%, with the use of complex treatment with the use of antihomotoxic drugs — 55.5%.

Construction of auditory bombardment therapy program: a pilot study

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Nahla Abd-ElAziz Rifaie ◽  
Dina Ahmed Elrefaie ◽  
Mona Mosaad Mahmoud
Keyword(s):  
Conventional Therapy ◽  
Speech Sound ◽  
University Hospitals ◽  
Speech Sound Disorder ◽  
Phonological Processes ◽  
Therapy Program ◽  
Significant Difference ◽  
Group 2 ◽  
Speech Segments ◽  
Group 1

Abstract Background Speech sound disorder is a communication disorder in which children have persistent difficulty saying words or sounds correctly. It refers to any difficulty or combination of difficulties with perception, motor production, or phonological representation of speech sounds and speech segments. Aim of the Work to construct an Arabic auditory bombardment therapy program and measure its effectiveness in treatment of functional speech sound disorder. Subjects and Methods This study was applied on 60 participants divided into 2 groups (30 for each group) with age ranging from 3-5 years diagnosed with functional speech sound disorder with or without language disorders, attending at the Phoniatrics outpatient clinic in Ain Shams University Hospitals. The test for identification of phonological processes was applied on 60 patients with speech sound disorder selected to participate in this study. These were divided in to 2 groups (Group (1) received only the conventional therapy while group (2) received auditory bombardment in addition to the conventional therapy for 3 months) and the test was repeated again after therapy. Results Group (2) showed high significant difference (improvement) in consonant assimilation, voicing change, final consonant deletion, palatal fronting, gliding, lateralization and glottal replacement while group (1) showed high significant difference (improvement) in syllable deletion and partial cluster reduction. Conclusion The present study showed that application of auditory bombardment therapy program in addition to conventional therapy has high significant improvement than conventional therapy alone.

Epiphora in patients after high-dose radioiodine therapy

2021 ◽  
pp. 54-55
Author(s):  
V.D. Yartsev ◽  
◽  
E.L. Atkova ◽  
Keyword(s):  
Radioiodine Therapy ◽  
Therapy Group ◽  
Nasolacrimal Duct ◽  
Positive Answer ◽  
Nasolacrimal Duct Obstruction ◽  
High Dose ◽  
Duct Obstruction ◽  
The Difference ◽  
Group 2 ◽  
Group 1

Purpose. To estimate the frequency of tearing in patients after high-dose radioiodine therapy. Materials and Methods. The survey was conducted in 500 patients after radioiodine therapy (group 1) and 654 volunteers (group 2). We asked whether the respondent noticed epiphora last month, in case of a positive answer we specified how many times during the day it was necessary to wipe the tear, comparing the result with Munk scale. Results. The patients of group 1 noticed tearing in 232 cases, the respondents of group 2 noticed it in 186 cases. Epiphora was more frequent in patients of group 1 (46 % of cases), rather than in volunteers of group 2 (27 % of cases). Excessive tearing was noticed in 8.8 % of patients of group 1 and 3.5 % of respondents of group 2. The difference was statistically significant. Conclusion. 8.8 % of patients complain about excessive tearing after high-dose radioiodine therapy, which is more frequent than in the general population. This may be related to secondary acquired nasolacrimal duct obstruction. Key words: epiphora, nasolacrimal duct obstruction, radioiodine therapy.

scholarly journals Experimental model for low level laser therapy on ischemic random skin flap in rats

2006 ◽  
Vol 21 (4) ◽  
pp. 258-262 ◽  
Author(s):  
Rodrigo Paschoal Prado ◽  
Richard Eloin Liebano ◽  
Bernardo Hochman ◽  
Carlos Eduardo Pinfildi ◽  
Lydia Masako Ferreira
Keyword(s):  
Laser Therapy ◽  
Experimental Model ◽  
Diode Laser ◽  
Skin Flap ◽  
Low Level Laser Therapy ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Group 2 ◽  
Group 1

PURPOSE: To develop an experimental model to be used in the study of low level Laser therapy on viability of random skin flap in rats. METHODS: The sample was 24 Wistar-EPM rats. The random skin flap measured 10 x 4 cm and a plastic sheet was interposed between the flap and donor site. Group 1 (control) underwent sham irradiation with diode laser (830 nm). Group 2 was submitted to laser irradiation with diode laser (830 nm). The animals were submitted to Laser therapy with 36 J/cm² energy density (72 seconds) immediately after the surgery and on the four subsequent days. The probe was usually held in contact with the skin flap surface on a point at 2.5 cm cranial from the flap base. On the seventh postoperative day, the percentage of necrotic area was measured and calculated. RESULTS: Group 1 reached an average necrotic area of 48.86%, Group 2 - 23.14%. After the statistic analysis, compared with the control group, Group 2 showed a statistically significant increase in survival area (p<0.001). CONCLUSION: The experimental model proved to be reliable to be used in the study of effects of low level laser therapy in random skin flap in rats.

scholarly journals Effect of the first and second postpartum partial milking on blood serum calcium concentration in dairy cows

2014 ◽  
Vol 59 (No. 3) ◽  
pp. 128-133
Author(s):  
E.G. Salgado-Hernández ◽  
A. Aparicio-Cecilio ◽  
F.H. Velásquez-Forero ◽  
D.A. Castillo-Mata
Keyword(s):  
Blood Serum ◽  
Dairy Cows ◽  
Serum Calcium ◽  
Metabolic Disorders ◽  
Calcium Concentration ◽  
Atomic Absorption Spectrophotometry ◽  
Serum Calcium Concentration ◽  
Group 2 ◽  
Group 1

Parturient paresis and subclinical hypocalcemia are frequent metabolic disorders in dairy cows postpartum. The aim of this study was to determine the effect of postpartum partial milking in the first two milkings on blood serum calcium concentration in dairy cows. Twenty multiparous Holstein dairy cows were randomized into two groups. Cows of group 1 (n = 10) were partially milked at the first and second milking postpartum. Cows of group 2 (n = 10) were completely milked. Blood samples were collected from all animals 5&ndash;7 days before calving, within 30 min after calving, and 4, 8, 12, 16, 20, 24, 28, and 32 h after calving for determination of serum calcium (Ca), phosphorus (P), and magnesium (Mg) concentrations. Colostrum production was registered and sampled in the first and second milking. Concentration of Ca in colostrum was determined by atomic absorption spectrophotometry. Serum Ca and P concentrations decreased in both groups after parturition (P &lt; 0.05) and remained low during 32 h postpartum with no difference observed between groups (P &gt; 0.05). Serum concentrations of Mg were stable in all samples and no statistical difference was observed between groups (P &gt; 0.05). Colostrum production was higher in completely milked cows only in the first postpartum milking (P &lt; 0.05), but there was no difference between groups at the second milking. Total Ca secretion in colostrum was higher in the complete milking group at the first and second postpartum milking. Colostrum Ca secretion increased at the second milking with respect to the first one in both groups (P &lt; 0.05). There was no correlation between serum Ca and colostrum Ca (P &gt; 0.05). In this study, the partial milking of colostrum in the first and second milking postpartum did not prevent subclinical hypocalcemia in dairy cows. &nbsp;

scholarly journals Evaluation of the Efficacy of 50% Autologous Serum Eye Drops in Different Ocular Surface Pathologies

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Francesco Semeraro ◽  
Eliana Forbice ◽  
Osvaldo Braga ◽  
Alessandro Bova ◽  
Attilio Di Salvatore ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Conventional Therapy ◽  
Keratoconjunctivitis Sicca ◽  
Signs And Symptoms ◽  
Autologous Serum ◽  
Eye Drops ◽  
Blurred Vision ◽  
Group 2 ◽  
Serum Eye Drops ◽  
Group 1

Purpose. This study evaluated the efficacy of 50% autologous serum eye drops in ocular surface diseases not improved by conventional therapy.Methods. We analyzed two groups: (1) acute eye pathologies (e.g., chemical burns) and (2) chronic eye pathologies (e.g., recurrent corneal erosion, neurotropic keratitis, and keratoconjunctivitis sicca). The patients were treated for surface instability after conventional therapy. The patients received therapy 5 times a day until stabilization of the framework; they then reduced therapy to 3 times a day for at least 3 months. We analyzed the best corrected visual acuity, epithelial defects, inflammation, corneal opacity, and corneal neovascularization. We also analyzed symptoms such as tearing, burning, sense of foreign body or sand, photophobia, blurred vision, and difficulty opening the eyelids.Results. We enrolled 15 eyes in group 1 and 11 eyes in group 2. The average therapy period was 16 ± 5.86 weeks in group 1 and 30.54 ± 20.33 weeks in group 2. The epithelial defects all resolved. Signs and symptoms improved in both groups. In group 2, the defect recurred after the suspension of therapy in 2 (18%) patients; in group 1, no defects recurred.Conclusions. Autologous serum eye drops effectively stabilize and improve signs and symptoms in eyes previously treated with conventional therapy.

Anticancer treatment and cognitive functions in elderly cancer patients: A prospective study

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 8543-8543
Author(s):  
A. M. Minisini ◽  
P. Ermacora ◽  
S. Russo ◽  
G. Cardellino ◽  
C. Andreetta ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Endocrine Therapy ◽  
Cognitive Functions ◽  
Therapy Group ◽  
Anxiety And Depression ◽  
Elderly Cancer Patients ◽  
Anticancer Treatment ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

8543 Background: It has been reported that anticancer treatment may alterate cognitive functions in cancer patients but very few prospective studied addressed this issue. Moreover, little is known about the cognitive impact of anticancer treatment in elderly cancer patients. We aimed at investigating the effect on cognitive functions of antiblastic chemotherapy and endocrine therapy in a consecutive series of elderly cancer outpatients. Methods: We evaluated cognitive functions by means of the Cambridge Cognitive Examination (CAMCOG) test and the Mini-Mental Scale Examination (MMSE) at baseline (before anticancer systemic treatment), after 3 months and after 6 months in cancer patients aged more than 65 years. Mood disturbances such as anxiety and depression were also evaluated (Hospital Anxiety and Depression Scale); comprehensive geriatric assessment and blood tests were performed at each evaluation. Results: Sixty patients were enrolled, 15 patients received chemotherapy (group 1), 13 patients received endocrine therapy (group 2) and 32 patients had neither chemotherapy nor endocrine therapy (group 3, control). Fifty-eight (97%) patients had no evidence of disease at the time of assessment. Median age was 71.5, 73 and 71 years in group 1, 2 and 3, respectively. At baseline, median Activities of Daily Living (ADL) score, Instrumental Activity of Daily Living (IADL) score, number of comorbidities and concomitant medications were 6, 8, 5, 1 in group 1, and 6, 8, 3, 2 in group 2, and 6, 8, 4, 2 in group 3, respectively. Median hemoglobin value was 12.9, 12.8, 13.3 g/dl in group 1, 2 and 3 respectively. At baseline, no significant unbalance was evident among groups. There was a statistically significant correlation between ADL or IADL score and CAMCOG total score (Spearman test, rho=0.4, p<0.05). Higher scolarity level was associated with higher CAMCOG total score. No deterioration of CAMCOG score was evident in group 1, 2 and 3 after 3 and 6 months (paired t-test p>.05); the separate analyses for the different items in CAMCOG test did not evidence any deterioration in time in the 3 groups. No worsening was seen in MMSE. Conclusions: Our study showed that anticancer treatment is not associated with rapid cognitive deterioration in elderly cancer patients. No significant financial relationships to disclose.

scholarly journals Efficacy of Clopidrogel on Reperfusion and High-Sensitivity C-Reactive Protein in Patients with Acute Myocardial Infarction

2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
Mehmet Akbulut ◽  
Makbule Kutlu ◽  
Yılmaz Ozbay ◽  
Veli Polat ◽  
Mehmet Nail Bilen ◽  
...  
Keyword(s):  
Therapy Group ◽  
High Sensitivity ◽  
Reperfusion Therapy ◽  
Early Reperfusion ◽  
Unfractioned Heparin ◽  
Reactive Protein ◽  
St Segment ◽  
Group 2 ◽  
Hs Crp ◽  
Group 1

We investigated the effects of clopidogrel on reperfusion and inflammatory process in STEMI. A total of 175 STEMI patients with similar clinical characteristics were included to this study. One was the standard pharmacological reperfusion therapy group (group 1,n: 90), who received 300 mg aspirin, 70 U/kg bolus, and 12 U/kg/hr continuous infusion of unfractioned heparin and accelerated t-PA. Clopidogrel 450 mg loading and 75 mg/d thereafter was added to standard reperfusion therapy in the other group (group 2,n: 85). The ST-segment resolution, CK-MB, and high-sensitive CRP (hs-CRP) parameters were measured. Complete ST resolution was observed in 32 patients (36.8%) in group 1 and 53 patients (63.8%) in group 2 (). Also in the first 24 hours, the CK-MB levels of patients in group 1 were significantly higher than those of group 2 (). The hs-CRP values were greater in group 1 than group 2 at 48th hour (gruop 1:  mg/L, group 2:  mg/L; ). We concluded that adding clopidogrel to standard treatment in STEMI patients provided early reperfusion and suppression of inflammatory response.

scholarly journals Complications of the Early Neonatal Period in Children from Mothers with Gestational Diabetes Mellitus

2021 ◽  
Vol 11 (4) ◽  
pp. 414-417
Author(s):  
Agamurad Orazmuradov ◽  
Irina Bekbaeva ◽  
Gayane Arakelyan ◽  
Anastasia Minaeva ◽  
Anastasiya Akhmatova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Therapy Group ◽  
Control Group ◽  
Balanced Diet ◽  
Functional Immaturity ◽  
Group 2 ◽  
Group 1

Background: Changes in the course of gestational diabetes mellitus (GDM) at the present stage determine the emergence of a certain spectrum of completely new problems associated with the health status of newborns from mothers with GDM. The aim of the study was to investigate early neonatal complications in newborns from mothers with GDM. Methods and Results: The study included 404 pregnant women (gestational age of 37.0–41.0 weeks) with GDM. All patients with GDM were divided into 2 groups. Group 1 included 188 patients receiving insulin therapy; Group 2 included 216 patients receiving a well-balanced diet. The control group (Group 3) consisted of 68 pregnant women without disorders of carbohydrate metabolism. In Group 1, macrosomia occurred in 44(23.4%) newborns, in Group 2 - in 48(22.0%) newborns; in newborns from mothers of the control group, the frequency of macrosomia was only in 7.35% of newborns (P=0.01). Morpho-functional immaturity of newborns had the highest frequency of occurrence, despite the fact that all children were born on time; 80(42.6%) newborns from mothers of Group 1 and 77(35.6%) newborns from mothers of Group 2 had signs of morpho-functional immaturity. Conclusion: Diabetic fetopathy in newborns from mothers with GDM is manifested by morpho-functional immaturity of organs and systems developing in unfavorable hyperglycemic conditions.

scholarly journals Emotional impairments and their correction in patients with migraine

2017 ◽  
Vol 89 (4) ◽  
pp. 75-79
Author(s):  
L S Chutko ◽  
S Yu Surushkina ◽  
E A Yakovenko ◽  
T I Anisimova ◽  
A V Sergeev
Keyword(s):  
Anxiety Disorders ◽  
Pain Intensity ◽  
Migraine Without Aura ◽  
Therapy Group ◽  
Vital Activity ◽  
Pronounced Decrease ◽  
Emotional Impairments ◽  
Clinical Presentations ◽  
Group 2 ◽  
Group 1

Aim. To study emotional impairments in patients with migraine and to evaluate the efficiency of Noophen therapy for this pathology. Subjects and methods. 63 patients aged 18 to 45 years with migraine without aura were examined. 56 patients used prophylactic antimigraine therapy: Group 1 (n = 26) received metoprolol and Group 2 took metoprolol in combination with Noophen. Results. The patients with migraine had a significantly higher level of alexithymia than the controls. Concomitant anxiety disorders were found in 47 (74.6%) cases. The study provided evidence that the treatment was highly effective in Group 2 that exhibited a more pronounced decrease in pain intensity, a greater reduction in the levels of anxiety, and more vital activity. Conclusion. The results of this study allow a conclusion that emotional impairments are implicated in the pathogenesis and clinical presentations of migraine and that it is appropriate to use Noophen for the treatment of this pathology.

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