scholarly journals Methodological approaches to determination of alcohol-related mortality in Russia and abroad

2012 ◽  
Vol 10 (4) ◽  
pp. 30-41 ◽  
Author(s):  
Andrey Gorgonyevich Solovyev ◽  
A M Vyazmin ◽  
E. A. Mordovskiy
Keyword(s):  
Human Health ◽  
Internal Structure ◽  
Alcohol Drinking ◽  
Medical Documentation ◽  
Attributable Mortality ◽  
Methodological Problems ◽  
Methodological Approaches ◽  
Related Mortality

The main methodological approaches to determination of alchol-related mortality (ARM), or alcohol-attributable mortality in Russia and abroad are revewed in the article. The characteristics of ARM as a phenomenon with complex internal structure have been done. The all alone conception of ARM as well as a number of its components are absent at the present time. The main methodological problems of identification of ARM in Russia and abroad are analyzed. The role of alcohol drinking pattern and dangerous influence of ethanol on human health are determined but only partially. The differences in determination of ARM in Russia and abroad have been revealed. The epidemiological approaches for determination of ARM without official statistics have got a number of objective reasons, e.g. first of all nonpossibility to determine all cases of mortality from alcohol-releted states registered by national services of statistics and low significance of primary medical documentation.

ІНТЕРПРЕТАЦІЯ КАТЕГОРІЇ РОЗВИТКУ В СУЧАСНІЙ ПСИХОЛОГІЇ

1970 ◽  
Vol 8 (1) ◽  
pp. 22-30
Author(s):  
Анжеліка Шамне
Keyword(s):  
Cultural Context ◽  
Developmental Psychology ◽  
Structure And Dynamics ◽  
Modern Psychology ◽  
Development Site ◽  
Approaches To Study ◽  
Methodological Approaches ◽  
Self Motion

У статті розглянуто сучасні підходи до інтерпретації категорії розвитку, розкрито теоретичні  та методологічні підходи до вивчення категорії розвитку у сучасній психології, визначено її психологічний  зміст,   моделі,   структуру   та   динаміку.   Категорія   розвитку   розглядається   як   епіцентр   наукової  проблематики у психології та як поняття інтегративного типу. Розвиток проаналізовано як категорію,  явище і проблему психології розвитку в різних аспектах аналізу. Розглянуто місце розвитку в системі  споріднених психологічних понять. У статті також аналізуються психологічні аспекти теоретичних та  методологічних  постнекласичних  тенденцій  вивчення  природи,  характеру  та  визначення  психічного  розвитку. Постнекласична парадигма та плюралістична методологія пізнання визначають розмитість  дисциплінарної мови  та  врахування  ролі  соціокультурного  контексту  при  вивченні  психологічних явищ.  Важливими тенденціями сучасного теоретико-методологічного стану психологічних досліджень розвитку  також є визнання неефективності моністичного підходу до його вивчення, взаємозв'язок теоретичних ідей  та   спроби   створення   метатеоретичних   схем,   постнекласичне   розуміння   розвитку   як   принципово  незавершеного   процесу   саморуху,   актуалізація   антропологічного   діапазону   проблем   та   посилення  спрямованості на роль культурного контексту в дослідженні розвитку людини.  The article deals with the modern approaches to the interpretation of the category of development, reveals  the theoretical and methodological approaches to study of development in modern psychology, its psychological  content, patterns, structure and dynamics. Category of development is viewed as an epicenter of scientific issues in  modern  psychology  and  the  concept  of  the  integrative  type.  Category  of  development  is  considered  as  the  phenomenon  and  the  problem  of  developmental  psychology  in  various  aspects  of  the  analysis.  Analyzed  the  development site in the related psychological concepts. The article analyzes the psychological aspects of theoretical  and methodological postnonclassical contemporary trends in the study of nature, character, and determination of  mental  development.  Postnonclassical  paradigm  and  pluralistic  methodology  of  knowledge  determine  the  disciplinary blurring and increase of the role of the analysis of socio-cultural context in the study of psychological  phenomenon. The important tendencies of modern theoretical and methodological state of psychological researches  of development are facts of inefficiency of the monistic approach to its study, interconnection of theoretical ideas  and   attempts   of  creating   metatheoretical   schemes,   postnonclassical   understanding   of   development   as   a  fundamentally  uncompleted  process  of  self-motion,  actualization  of  anthropological  range  of  problems  and  strengthening of focus on the role of cultural context in research of human development.   

scholarly journals Methodology of The Initial Stage of The Preparation of The Master’s Thesis on Criminal Law

2020 ◽  
Vol 79 ◽  
pp. 02011
Author(s):  
Alexander M. Pleshakov ◽  
Gennadiy S. Shkabin
Keyword(s):  
Criminal Law ◽  
Legal System ◽  
Scientific Work ◽  
Research Activities ◽  
Initial Stage ◽  
Master's Thesis ◽  
Methodological Problems ◽  
Methodological Approaches ◽  
Goals And Objectives

The modern legal system of any state imposes high requirements to specialists in this field, primarily related to the use of large amounts of information in the work. In this regard, the scientific work of students, aimed at forming the need for research activities, becomes particularly relevant. One of its final stages is the preparation of a master’s thesis. Scientific and pedagogical experience of the authors allows stating that the majority of applicants face difficulties in choosing and justifying the topic of the research. The article considers methodological approaches to determining the boundaries and the volume of study of the material, its generalization, and formulation of the title of the thesis. The mechanisms of determination of social conditionality, elaboration, object, and subject of the forthcoming dissertation on criminal law are investigated. The objectives are to pro-vide the reader with an accessible mechanism for selecting the topic of scientific work, justifying its relevance, methodology, and setting goals and objectives. Results of work are expressed in the identification of methodological problems that arise in the course of writing the master’s thesis, as well as recommendations on the organization of the initial stage of the thesis preparation.

The role of the main ingredients of chocolate in the formation of its beneficial properties for the consumer

2021 ◽  
pp. 582-587
Author(s):  
I.V. Goloviznin ◽  
A.V. Ryzhakova
Keyword(s):  
Human Health ◽  
Complete Information ◽  
The Body ◽  
Specific Product ◽  
Regular Process ◽  
The World ◽  
The Impact ◽  
Confectionery Product

Chocolate is the most staple and consumed confectionery product in Russia and the world. The determination of the beneficial properties of such a product as chocolate is an important and regular process of food institutions in every country, since new lines of already well-known manufacturers and new manufacturers with an innovative assortment are added to the retail assortment. Today, it is very relevant and important to understand the impact of new products on human health. In this regard, in order to provide complete information on a specific product, it is necessary to know its composition, ingredients and their effect on the body separately and within the framework of a specific product. Along with its beneficial properties, chocolate can also affect health negatively. It is necessary to understand the mechanism of the effect of chocolate on human health when consumed and to assess the risks that may arise subsequently after its active consumption.

scholarly journals THEORY AND METHODOLOGY OF ECONOMIC EVALUATION OF HUMAN HEALTH DAMAGE CAUSED BY NEGATIVE ECOLOGICAL EXPOSURE

2020 ◽  
Vol 70 (4/2020) ◽  
pp. 42-54
Author(s):  
V. V. Dyadik ◽  
◽  
N. V. Dyadik ◽  
E. M. Klyuchnikova ◽  
◽  
...  
Keyword(s):  
Willingness To Pay ◽  
Human Health ◽  
Internal Structure ◽  
Environmental Impacts ◽  
Negative Consequences ◽  
Advantages And Disadvantages ◽  
Health Damage ◽  
Methodological Approaches ◽  
The Cost ◽  
Theoretical Foundations

This article is devoted to a review of the theoretical foundations and methodological approaches to solving the problem of assessing the negative consequences for human health caused by anthropogenic environmental impacts. The authors analyze the goals, internal motives and types of damage assessments carried out by various researchers, determine the projections and measurements of the socio-economic category of damage. The study shows the main stages of the basic algorithm for the valuation of health damage. Two main methodological approaches to assessment are disclosed: the calculation of costs due to the negative impact and the assessment of the willingness to pay for risk prevention. The history of the emergence of these approaches, theoretical foundations, advantages and disadvantages, internal structure and logic of work are presented. In particular, with regard to the approach based on the determination of the cost of disease, the categories of cost directions that form its internal structure, research prospects and competing approaches to determining the cost of indirect costs are disclosed. In relation to the willingness to pay approach, a decomposition of economic terms is presented that determine the amount that the respondent is willing to pay for the agreed risk reduction. The basic economic components of the utility category for determining the willingness to pay have been determined. Analyzing various approaches to assessing damage, the authors make an attempt to determine the areas of their possible application in the implementation of scientific research and applied developments. Based on the analysis of the dynamics of the publication of research results, assumptions were made about the development trends of the two prevailing methodological approaches to assessing damage to human health in the world and in Russia, with substantiation of the underlying causes. A forecast has been made on the further evolution of the methodology for assessing damage to human health from adverse environmental impacts in Russia.

scholarly journals ANTINOMIES OF RESEARCH METHODS IN SOCIAL SCIENCES: METHODENSTREIT

2017 ◽  
pp. 089
Author(s):  
Jelena Božilovć
Keyword(s):  
Social Sciences ◽  
Ancient Philosophy ◽  
Essential Difference ◽  
Social Phenomena ◽  
History Of ◽  
Ideological Background ◽  
Methodological Problems ◽  
Methodological Approaches ◽  
The Times

The central issue of this paper is the so-called dispute over methods (Methodenstreit), which is based on the essential difference between natural and social phenomena. Methodological problems in sociology are related to the determination of its subject matter, and the history of the science has showed that these problems have represented the main point of disagreement between theoreticians. The debates on the issues of natural and social phenomena and, thus related, manners of their examination, began as early as in the times of ancient philosophy – starting with Aristotle, and continued through the so-called Galilean tradition that would find its peak in the positivist movement and the historistic school as its opposition. The paper draws attention to the theoretical-methodological positions of both sides in this dispute, the reaffirmation of hermeneutics, as well as the ideological background. Furthermore, certain opinions that formed through the integration of these two methodological approaches are also discussed here. The time of the Methodenstreit is the time when sociology was constituted, thus the concluding remarks emphasize the importance of this dispute for the constitution of sociology as a science, with a particular reflection on the influence of historism on German sociologists.

A Molecular Approach to Immunoscintigraphy: A Study of the T-Antigen Conformation on the Surface of Tumors

1987 ◽  
Vol 26 (01) ◽  
pp. 1-6 ◽  
Author(s):  
S. Selvaraj ◽  
M. R. Suresh ◽  
G. McLean ◽  
D. Willans ◽  
C. Turner ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Tumor Cell ◽  
T Antigen ◽  
Human Carcinomas ◽  
Animal Tumor ◽  
Synthetic Antigens

The role of glycoconjugates in tumor cell differentiation has been well documented. We have examined the expression of the two anomers of the Thomsen-Friedenreich antigen on the surface of human, canine and murine tumor cell membranes both in vitro and in vivo. This has been accomplished through the synthesis of the disaccharide terminal residues in both a and ß configuration. Both entities were used to generate murine monoclonal antibodies which recognized the carbohydrate determinants. The determination of fine specificities of these antibodies was effected by means of cellular uptake, immunohistopathology and immunoscintigraphy. Examination of pathological specimens of human and canine tumor tissue indicated that the expressed antigen was in the β configuration. More than 89% of all human carcinomas tested expressed the antigen in the above anomeric form. The combination of synthetic antigens and monoclonal antibodies raised specifically against them provide us with invaluable tools for the study of tumor marker expression in humans and their respective animal tumor models.

On The Mechanism Of Heparin-Induced Potentiation Of Platelet Aggregation

1981 ◽  
Author(s):  
M Yamamoto ◽  
K Watanabe ◽  
Y Ando ◽  
H Iri ◽  
N Fujiyama ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Platelet Activation ◽  
Coagulation Factors ◽  
Marked Enhancement ◽  
Matrix Bound ◽  
Induced Aggregation ◽  
Aggregation Of Platelets ◽  
Plasma Heparin

It has been suggested that heparin caused potentiation of aggregation induced by ADP or epinephrine. The exact mechanism of heparin-induced platelet activation, however, remained unknown. In this paper, we have investigated the role of anti-thrombin III ( AT ) in heparin-induced platelet activation using purified AT and AT depleted plasma. When ADP or epinephrine was added to citrated PRP one minute after addition of heparin ( 1 u/ml, porcine intestinal mucosal heparin, Sigma Co. USA ), marked enhancement of platelet aggregation was observed, compared with the degree of aggregation in the absence of heparin. However, in platelet suspensions prepared in modified Tyrode’s solution, heparin exhibited no potentiating effect on platelet aggregation induced by epinephrine or ADP. Potentiation of epinephrine- or ADP-induced platelet aggregation by heparin was demonstrated when purified AT was added to platelet suspensions at a concentration of 20 μg/ml. AT depleted plasma, which was prepared by immunosorption using matrix-bound antibodies to AT, retained no AT, while determination of α1-antitrypsinα2- macroglobulin and fibrinogen in AT depleted plasma produced values which corresponded to those of the original plasma when dilution factor was taken into account. The activities of coagulation factors were also comparable to those of the original plasma. Heparin exhibited potentiating effect on ADP- or epinephrine-induced aggregation of platelets in original plasma, but no effect in AT depleted plasma. When purified AT was added back to AT depleted plasma at a concentration of 20 μg/ml, potentiation of platelet aggregation by heparin was clearly demonstrated.Our results suggest that effect of heparin on platelet aggregation is also mediated by anti-thrombin III.

Role of the family focused technologies in the clinical course of pregnancy at women of high obstetric risk

2016 ◽  
pp. 64-66
Author(s):  
S.Yu. Vdovichenko ◽  
Keyword(s):  
Comparison Group ◽  
Traditional Approach ◽  
Married Couple ◽  
Premature Births ◽  
Individual Support ◽  
The Family ◽  
Risk Patients ◽  
Individual Preparation

The objective: to show a role of the family focused technologies in depression of frequency of pathology of pregnancy at women of high obstetric risk. Patients and methods. For determination of efficiency of prophylaxis of pathology of pregnancy on the basis of use of the family focused technologies complex clinical-psychological and laboratory and tool examination of 300 women with factors of obstetric risk which were divided into two groups was conducted. In the main group – 182 women with motivation on partner labors to which provided training on system of individual preparation of married couple to labors. The comparison group consisted of 118 women who were not in prenatal training and had individual support in childbirth, with the traditional approach to pain management. Results. Use of the family focused technologies during pregnancy allows to reduce significantly the frequency of the main complications of pregnancy, especially not incubation and premature births. Conclusion. In our opinion, the technique is simple, available and can widely be used in practical health care at women with high obstetric risk. Key words: obstetric risk, the family focused technologies, prophylaxis.

The Impact of Quantitative Easing on Emerging Markets – Literature Review

e-Finanse ◽  
2018 ◽  
Vol 14 (4) ◽  
pp. 67-76
Author(s):  
Piotr Bartkiewicz
Keyword(s):  
Emerging Markets ◽  
Large Scale ◽  
Empirical Literature ◽  
Quantitative Easing ◽  
Methodological Choices ◽  
The Subject ◽  
Methodological Approaches ◽  
The Impact ◽  
Sufficient Precision

AbstractThe article presents the results of the review of the empirical literature regarding the impact of quantitative easing (QE) on emerging markets (EMs). The subject is of interest to policymakers and researchers due to the increasingly larger role of EMs in the world economy and the large-scale capital flows occurring after 2009. The review is conducted in a systematic manner and takes into consideration different methodological choices, samples and measurement issues. The paper puts the summarized results in the context of transmission channels identified in the literature. There are few distinct methodological approaches present in the literature. While there is a consensus regarding the direction of the impact of QE on EMs, its size and durability have not yet been assessed with sufficient precision. In addition, there are clear gaps in the empirical findings, not least related to relative underrepresentation of the CEE region (in particular, Poland).

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