School on HIV infection for future doctors of various specialties Vera HIV med school: importance and value for a young doctor

2021 ◽  
Vol 24 (4) ◽  
pp. 39-44
Author(s):  
Irina R. Abitova
Keyword(s):  
Family Medicine ◽  
Hiv Infection ◽  
Health Sector ◽  
People Living With Hiv ◽  
Young Doctor ◽  
Western State ◽  
The North ◽  
Living With Hiv ◽  
Medical University ◽  
North Western

The article presents a brief overview of the materials received by the author in September 2020 at the School HIV infection for future doctors of various specialties (Moscow), in which she participated as a resident of the Department of Family Medicine of the North-Western State Medical University named I.I. Mechnikov. The goal of the School is to raise the awareness of young doctors on the topic of HIV infection and reduce the level of discrimination against people living with HIV in the health sector.

scholarly journals Barriers in providing tuberculosis services for people living with HIV and their overcoming

2019 ◽  
Vol 100 (3) ◽  
pp. 482-487
Author(s):  
Z M Zagdyn
Keyword(s):  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Drug Users ◽  
Government Support ◽  
People Living With Hiv ◽  
Regional Government ◽  
Adequate Treatment ◽  
North West ◽  
The North ◽  
Living With Hiv

Aim. To study the opinions of specialists in tuberculosis institutions on barriers and ways to improve the system fighting the spread of human immunodeficiency virus (HIV) and tuberculosis. Methods. In the study questionnaires with open and closed questions were used among employees of tuberculosis facilities in four territories of the North-West Region of Russia (Saint-Petersburg, Leningrad, Arkhangelsk, and Kaliningrad oblasts) during six months in 2018. Total of 284 subjects were included. The questionnaire consisted of 19 structured questions. The respondents’ answers were compared interregionally and were analyzed integrally inside the blocks with the calculation of their ratios. Results. According to the specialists’ opinion working in tuberculosis facilities, the main barriers to providing tuberculosis services for people living with HIV are low level of intersectoral interaction, migration, increase in the number of injecting drug users, lack of regional government support, inconsistency of regulation documents with the requirements of currant reality. As the main conditions for improvement of epidemic situation with association of HIV/tuberculosis, the respondents consider increasing administration of antiretroviral therapy to the patients with HIV, adequate treatment of tuberculosis in HIV-infection and raising awareness of HIV-infection and tuberculosis by the population. Conclusion. To improve the existing system of fighting HIV/tuberculosis, strengthening the connection among the stakeholders may be possible, especially between tuberculosis facilities and detention centers giving the valuable access to antiretroviral therapy, chemoprophylaxis and tuberculosis treatment, including establishment of low-threshold centers, improved population awareness of tuberculosis and HIV-infection.

scholarly journals Chronicle of family medicine: view from iowa city (USA)

2017 ◽  
Vol 21 (2) ◽  
pp. 27-34
Author(s):  
Galina V Kiseleva ◽  
Ekaterina G Bukiia
Keyword(s):  
Health Care ◽  
Family Medicine ◽  
Education System ◽  
Iowa City ◽  
Western State ◽  
Medical University ◽  
North Western

The article presents a brief essay about the training of two representatives of the department of family medicine of North-Western State Medical University named after I.I. Mechnikov in April - May 2017 in the Iowa University (USA) dedicated to study of education system and organization of health care in America.

Features of the clinical course of a new coronavirus infection in students who were under observation in the observatory

2021 ◽  
Vol 24 (4) ◽  
pp. 5-12
Author(s):  
Olga Yu. Kuznetsova ◽  
Anna V. Lubimova ◽  
Karina V. Ovakimyan ◽  
Olga S. Zamyatina ◽  
Nikita V. Donetskov
Keyword(s):  
Prospective Study ◽  
Close Contact ◽  
Severe Disease ◽  
Western State ◽  
The North ◽  
Significant Difference ◽  
Coronavirus Infection ◽  
A Prospective Study ◽  
Medical University ◽  
North Western

The emerging epidemic of a new coronavirus infection (COVID-19), received the status of an emergency of international importance and attracted the attention of not only health professionals, but also the population around the world. Although the risk of severe health consequences from COVID-19 for young people without comorbidities is relatively low, an increase in the incidence of infection in this age group may lead to an increase in the proportion of people with severe disease, as well as the spread of infection among older age groups who are in close contact with them and are at high risk of mortality from COVID-19. The aim of the study was to evaluate the clinical features of the new coronavirus infection among students of the North-Western State Medical University named after I.I. Mechnikov, placed in the observatory. Materials and methods. The study was conducted on the basis of the observatory of the North-Western State Medical University named after I.I. Mechnikov. All persons transferred to the observatory in the period from 21.04.2020 to 31.08.2020, epidemiological and clinical-anamnestic data were recorded. In a prospective study, all participants were asked to complete a Health Questionnaire (EQ-5D) over the phone 3 months after their stay at the observatory. Results. 113 people participated in the study: 45.1% of men (n = 51) and 54.9% of women (n = 62). The average age of the respondents was 22.4 2.5 years. When conducting a multivariate analysis, it was found that gender, age, belonging to an ethno-linguistic group, and chronic diseases are not reliable factors associated with the development of COVID-19 participants. According to the results of a prospective study, a statistically significant difference between the responses of respondents who had and did not have COVID-19 was obtained with a positive answer to the question about the presence of pain and discomfort (p 0.05).

Opinion of students of medical university on methods of contraception and prevention of unwanted pregnancy

2021 ◽  
Vol 24 (4) ◽  
pp. 19-24
Author(s):  
Anatoliy К. Lebedev ◽  
Elizaveta A. Redka ◽  
Anastasia M. Bugay ◽  
Elizaveta O. Lunenkova ◽  
Maria N. Sokolova
Keyword(s):  
Informed Consent ◽  
Young Women ◽  
Unwanted Pregnancy ◽  
Scientific Research ◽  
State University ◽  
Contraceptive Methods ◽  
Western State ◽  
The North ◽  
Medical University ◽  
North Western

The article analyzes an opinion of 6th grade of young women, the 6th grade medicine students, on the topic of using contraceptive methods for preventing unwanted pregnancy. In the North-Western State University named after I.I. Mechnikov an anonymous poll was conducted by filling specially prepared questionnaires, that included 29 questions and informed consent for using the results of the survey in scientific research. The study included an opinion of 300 6th grade students with the age 22 to 33 years. The results of the survey about the most frequently used contraception methods by 6th grade students was provided as well as the purpose of using certain modern types of contraception, the awareness of students about the chosen methods of contraception.

Assessment of coronary inflammation in antiretroviral treated people living with HIV infection and active HIV/HCV co-infection

AIDS ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jean Jeudy ◽  
Pratik Patel ◽  
Nivya George ◽  
Shana Burrowes ◽  
Jennifer Husson ◽  
...  
Keyword(s):  
Hiv Infection ◽  
People Living With Hiv ◽  
Living With Hiv

Health-related quality of life of people living with HIV infection in Spain: a gender perspective

AIDS Care ◽  
2019 ◽  
Vol 31 (12) ◽  
pp. 1509-1517 ◽  
Author(s):  
Carmina R. Fumaz ◽  
Maider Larrañaga-Eguilegor ◽  
Sonia Mayordomo-López ◽  
Sandra Gómez-Martínez ◽  
Marian González-García ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hiv Infection ◽  
People Living With Hiv ◽  
Health Related Quality ◽  
Gender Perspective ◽  
Related Quality ◽  
Health Related ◽  
Living With Hiv

scholarly journals HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Farina Karim ◽  
Inbal Gazy ◽  
Sandile Cele ◽  
Yenzekile Zungu ◽  
Robert Krause ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Disease Severity ◽  
Immune Cell ◽  
Supplemental Oxygen ◽  
People Living With Hiv ◽  
Cell Counts ◽  
Cell Changes ◽  
Living With Hiv ◽  
Second Wave ◽  
Hiv Negative

There are conflicting reports on the effects of HIV on COVID-19. Here we analyzed disease severity and immune cell changes during and after SARS-CoV-2 infection in 236 participants from South Africa, of which 39% were people living with HIV (PLWH), during the first and second (beta dominated) infection waves. The second wave had more PLWH requiring supplemental oxygen relative to HIV negative participants. Higher disease severity was associated with low CD4 T cell counts and higher neutrophil to lymphocyte ratios (NLR). Yet, CD4 counts recovered and NLR stabilized after SARS-CoV-2 clearance in wave 2 infected PLWH, arguing for an interaction between SARS-CoV-2 and HIV infection leading to low CD4 and high NLR. The first infection wave, where severity in HIV negative and PLWH was similar, still showed some HIV modulation of SARS-CoV-2 immune responses. Therefore, HIV infection can synergize with the SARS-CoV-2 variant to change COVID-19 outcomes.

scholarly journals Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

2022 ◽  
Vol 5 (1) ◽  
Author(s):  
Flora Mikaeloff ◽  
Sara Svensson Akusjärvi ◽  
George Mondinde Ikomey ◽  
Shuba Krishnan ◽  
Maike Sperk ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Cell Model ◽  
Antiretroviral Drugs ◽  
Metabolic Reprogramming ◽  
System Level ◽  
People Living With Hiv ◽  
Low Grade ◽  
Middle Income ◽  
Living With Hiv

AbstractDespite successful combination antiretroviral therapy (cART), persistent low-grade immune activation together with inflammation and toxic antiretroviral drugs can lead to long-lasting metabolic flexibility and adaptation in people living with HIV (PLWH). Our study investigated alterations in the plasma metabolic profiles by comparing PLWH on long-term cART(>5 years) and matched HIV-negative controls (HC) in two cohorts from low- and middle-income countries (LMIC), Cameroon, and India, respectively, to understand the system-level dysregulation in HIV-infection. Using untargeted and targeted LC-MS/MS-based metabolic profiling and applying advanced system biology methods, an altered amino acid metabolism, more specifically to glutaminolysis in PLWH than HC were reported. A significantly lower level of neurosteroids was observed in both cohorts and could potentiate neurological impairments in PLWH. Further, modulation of cellular glutaminolysis promoted increased cell death and latency reversal in pre-monocytic HIV-1 latent cell model U1, which may be essential for the clearance of the inducible reservoir in HIV-integrated cells.

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