scholarly journals Composition of Vaginal microbiota and their antibiotic susceptibility in symptomatic women

2017 ◽  
Vol 6 (2) ◽  
pp. 427
Author(s):  
Ushadevi Gopalan ◽  
Sathiyakala Rajendiran ◽  
Karthika Jayakumar ◽  
Ranganathan Karnaboopathy
Keyword(s):  
Candida Species ◽  
Antibiotic Susceptibility ◽  
Pathogenic Bacteria ◽  
Vaginal Discharge ◽  
Tertiary Care ◽  
Vaginal Swab ◽  
Reproductive Age ◽  
Klebsiella Pneumonia ◽  
Care Hospital ◽  
Age Group

Background: Bacterial vaginosis is the most prevalent lower genital tract infection in women of reproductive age. The aim of this study was to identify the causative organism in patients with vaginal discharge and to study the sensitivity of the organism to antibiotics.Methods: This was a hospital based prospective study in Department of Obstetrics and Gynecology in a tertiary care hospital over a period of two years. 2062 women with complaints of vaginal discharge were subjected to a high vaginal swab and the sample was cultured, the organisms were identified and antibiotic susceptibility was tested.Results: There was no growth found in 40.7% of patients. E. coli was found to be the most common organism isolated followed by Klebsiella pneumonia and Klebsiella oxytoca. Candida species was isolated in 1.4 % of women. An increased frequency of vaginal infection was found in the age group 26-35 years, followed by age group 36-45 years. 73.2% of the organisms were sensitive to Imipenam, 70.4 % to Amikacin and 65.7% to Gentamycin. There were 10 MRSA strains isolated all of which were sensitive to Vancomycin, Amikacin and Gentamycin.Conclusions: Our study provides information about the different microorganisms present in women with vaginal discharge. Since pathogenic bacteria were more common than Candida species it is recommended to offer treatment to patients after taking a high vaginal swab. Appropriate antibiotics based on culture and sensitivity has to be given along with antifungal agents.

scholarly journals Etiologic characterization of vulvovaginitis among females attending a tertiary care hospital: a one year study

2017 ◽  
Vol 6 (6) ◽  
pp. 2246
Author(s):  
Chembetei Kavitha Kiran ◽  
Jithendra Kandati ◽  
Munilakshmi Ponugoti
Keyword(s):  
Risk Factors ◽  
Bacterial Vaginosis ◽  
Vaginal Discharge ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Increased Risk ◽  
One Year

Background: Vulvovaginitis is one among the major pathologies encountered in reproductive age group. Etiologies are always multiple and candidiasis, bacterial vaginitis and trichomoniasis account for 90% of etiology. The incidence is dependable upon multiple factors like age group, ethnicity, socioeconomic status, geographical locale. Improperly treated and untreated vulvovaginitis is associated with long term complications like infertility, pelvic inflammatory disease in nulliparous females and preterm labour, miscarriage, ectopic pregnancy, chorioamnionitis among pregnant females and recurrent UTIs, cervicitis, endometritis, increased risk of acquiring STIs among normal females. The present study was undertaken with the objective of understanding the etiologies associated with vulvovaginitis among women attending Obstetrics clinic of a tertiary care hospital. The risk factors associated with the conditions, the features of the vaginal discharge and symptoms associated with each etiology were studied.Methods: A cross sectional study for a period of one year was conducted among 200 female patients attending the Department of gynecology for vaginitis and evaluated for etiology. Patient’s risk factors, clinical history, symptoms were collected by questionnaire and specimens were collected from all the cases and processed as per standard guidelines. Bacterial vaginosis was confirmed based on Neugent’s criteria, Trichomoniasis by wet mount examination and candidiasis by culture. The study was approved by the institutional ethical committee.Results: 137 cases of vulvovaginitis were diagnosed based on etiology. Vulvovaginitis was most common among 27-36 years and in multiparous women. Most common causative agent was Candida (59.12%) followed by bacterial vaginosis (22.63%) and Trichomoniasis (18.25%). Vaginal discharge was the commonest symptom (100%) followed by malodor and vulval irritation. Following unhygienic practices was the commonest risk factor associated with Vulvovaginitis.Conclusions: A regular evaluation is mandatory for all the females attending hospital for vaginitis. Successful management reduces the morbid conditions and it’s essential to treat the conditions during the pregnancy which prevents the complications associated like preterm birth, miscarriage etc. and adverse outcomes.

scholarly journals A clinico-histopathological review of ovarian masses at a tertiary care centre

2018 ◽  
Vol 7 (10) ◽  
pp. 4139
Author(s):  
Michelle N. Fonseca ◽  
Madhavi J.
Keyword(s):  
Tertiary Care ◽  
Young Patients ◽  
Mucinous Cystadenoma ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Benign Ovarian Tumours ◽  
Ovarian Tumours ◽  
Ovarian Masses

Background: Ovarian tumours can be seen at all stages of life but they differ in type, being mostly germ cell tumours in childhood, functional cysts in the reproductive age group (up to 45 years) and becoming increasingly malignant towards and after menopause. It also accounts for most prevalent cause of hospital admissions.Methods: This is a retrospective study conducted in the Department of Obstetrics and Gynaecology at a tertiary care hospital in Mumbai from August 2017 to August 2018. All patients with ovarian masses who were surgically managed were included in the study. The data of 30 patients was collected in excel sheet and analyzed by descriptive statistics.Results: Out of the 30 ovarian masses, 50 % were functional cysts, 46.6% were benign ovarian masses and 3.3% were borderline malignant. 46% of tumours were seen in the age group 21-30 years. More than 50 % tumours were seen in parous women. Most common presenting clinical symptom was pain in abdomen irrespective of the type of tumour. Most common complication was haemorrhage in the cyst. Laparoscopy was done in 4 patients and 26 required exploratory laparotomy. Most common surgery performed was unilateral cystectomy for functional ovarian cysts and benign ovarian tumours. Mucinous cystadenoma was the most common benign ovarian tumour, followed by dermoid cyst.Conclusions: Pre-operative diagnostic approach to a patient with ovarian mass includes careful history taking, thorough clinical examination, ultrasound and tumour marker assays in selected cases. Conservative surgery should be the goal to preserve fertility in young patients with ovarian tumours.

scholarly journals Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020

2020 ◽  
Vol 24 (4) ◽  
pp. 348-352
Author(s):  
Nusrat Noor ◽  
Rabiah Anwar ◽  
Rabia Akbar ◽  
Ghazala Sadaf ◽  
Khan M Yaqub
Keyword(s):  
Sensitivity And Specificity ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Military Hospital ◽  
Outpatient Basis ◽  
Care Hospital ◽  
Age Group ◽  
Endometrial Sampling ◽  
Post Menopausal ◽  
Endometrial Pathology

ABSTRACT Objective: To assess the effectiveness and enlist clinical factors, which may affect effectiveness of Pipelle sampling in diagnosing endometrial pathology in patients with abnormal uterine bleeding and Post-menopausal Bleeding. Study Design: ‘Analytical Cross-Sectional’ study. Place and duration: Gynecology Department at Combined Military Hospital Rawalpindi, in collaboration with Histo-Pathology Department, of six months duration i.e. from 1st  December 2019 to 31st May 2020. Patients and methods: 100 female patients of outpatient department with presenting complaints of either abnormal or post-menopausal bleeding were included in the study in the specified time frame. After informed written consent, Pipelle endometrial sampling was done on outpatient basis, and by consecutive sampling technique using lottery method, sample was sent for histopathological evaluation. Evaluated factors studied were:  indications for the procedure, age, parity, age of menarche. Results: Of the total patients evaluated, 91% (n=100) were non-malignant, while 4% (n=100) were malignant. Inadequate tissue was obtained in 5% samples. Most common histopathological findings among reproductive age group were Proliferative and Secretory phase endometrium 64% (n=100). While in Post-menopausal age group 4% (n=100) were Endometrial carcinoma on histopathology. Inadequate tissue samples 5% (n=100) were noted among the Post-menopausal group. 6% samples showed endometrial hyperplasia. Pipelle Endometrial Sampling had sensitivity and specificity, in diagnosing the endometrial pathologies is summarized in Table 3. Conclusion: Pipelle Endometrial Sampling is an effective, safe, simple and acceptable procedure for diagnosing endometrial pathology. It is cost effective requiring no anesthesia with high sensitivity and specificity for detecting endometrial pathology.  

scholarly journals Quality of Life and Stigma among Women with Epilepsy during Their Reproductive Years

2021 ◽  
Vol 11 (1) ◽  
pp. 63-71
Author(s):  
Pallerla Srikanth ◽  
Mysore Narasimha Vranda ◽  
Priya Treesa Thomas ◽  
Kenchaiah Raghvendra
Keyword(s):  
Quality Of Life ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Stigma Scale ◽  
The Impact ◽  
The Relationship ◽  
Reproductive Age Group

Background and Purpose: The purpose of this study was to understand the relationship between quality of life and stigma among reproductive age group women with epilepsy.Methods: A cross-sectional descriptive study was conducted to assess the data from the 49 women with epilepsy from a tertiary care hospital in India. Quality of life was evaluated with the quality of life in epilepsy-31 questionnaire and stigma was evaluated with the stigma scale of epilepsy. Data also included socio-demographic and clinical characteristics.Results: The mean age of the participants was 24.67±3.72 years. Quality of life total score (r=-0.485**) and seizure worry domain (r=-0.427**) were significantly negatively correlated with stigma total score at p<0.01 level. Being uneducated, married, unemployed, having children, having generalized tonic-clonic seizures, duration of illness (˃10 years), and consuming levetiracetam, anti-epileptic drug (AED), were the significant contributing factors for low quality of life among women with epilepsy during the reproductive age group. Belonging to lower socio-economic status and taking more than two AEDs were also associated with lower quality of life among women with epilepsy, which are trending towards significance.Conclusions: The study assessed the relationship between the quality of life and the Stigma scale of epilepsy and demonstrated the impact of stigma and quality of life on socio-demographic and clinical variables of women with epilepsy under the reproductive age group. To enhance the quality of life and reduce the stigma levels among women with epilepsy, some of the modifiable parameters can be considered by the multidisciplinary health care professionals from the findings of the current research.

scholarly journals Socio-demographic Characteristics and Incidence of CIN of Uterine Cervix among VIA Positive Women attended at a Tertiary Care Hospital in Dhaka City

2020 ◽  
Vol 7 (1) ◽  
pp. 7-11
Author(s):  
Khurshida Samad ◽  
Imtiaz Ahmed ◽  
Touhid Uddin Rupom ◽  
Fouzia Jahan ◽  
Shimul Akter
Keyword(s):  
Cervical Intraepithelial Neoplasia ◽  
Uterine Cervix ◽  
Tertiary Care ◽  
Intraepithelial Neoplasia ◽  
Lower Class ◽  
Demographic Characteristics ◽  
Reproductive Age ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional

Background: Women in different socio-demographic are presented with VIA positivity. Objective: The purpose of the present study was to see the socio-demographic characteristics and incidence of CIN of uterine cervix among of VIA positive women. Methodology: This cross sectional study was conducted in the Department Of Pathology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh during the period of July 2007 to June 2008 for one (01) year. Patients who were colposcopically positive for cervical intraepithelial neoplasia and early invasive carcinoma or patients who are colposcopically negative but clinically suspicious for cervical neoplasia were included in this study. The clinical history was obtained by taking history with particular attention to age, age at marriage, parity, history of contraceptives, abnormal per vaginal discharge and post coital bleeding. The cervix was examined on naked eye by Cusco’s speculum to see whether it was healthy or not. Then it was examined by the colposcope after applying 3.0 to 5.0% acetic acid and colposcopic findings were collected. VIA positive cases were underwent colposcopy guided LEEP biopsy. Result: A total of 63 patients of different age group were recruited for this study. The mean with SD of age of this study population was 34.6±9.59 years. In this study, 41(65%) cases were diagnosed as cervical intraepithelial neoplasia (CIN). Incidence of CIN-I was 10 cases in age group 20 to 29 years. Most of the cases were in 30 to 39 (18 cases) years age group. Among 20 cases of high grade lesion (CIN-II/III) 9(45%) cases were in lower class, 8(40%) cases were in middle class and 3(15%) cases in upper class. Conclusion: In conclusion majority of the women were middle aged reproductive age group who are mostly in the lower class of socioeconomic class. Journal of Current and Advance Medical Research 2020;7(1): 7-11

scholarly journals Prevalence of bacterial vaginosis among reproductive age group women in a tertiary care centre

2019 ◽  
Vol 8 (11) ◽  
pp. 4515
Author(s):  
Rema V. Nair ◽  
Raja Preethi ◽  
M. Vijayalekshmi
Keyword(s):  
Bacterial Vaginosis ◽  
Vaginal Discharge ◽  
Early Stage ◽  
Strong Association ◽  
Tertiary Care ◽  
Reproductive Age ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Reproductive Age Group

Background: Vaginal discharge in reproductive age poses a serious problem in the developing countries. Bacterial vaginosis also known as non-specific vaginitis is the most common cause of vaginal infections, detecting the organism at an early stage and initiating a proper treatment is very difficult in our country due to lack of awareness and proper follow-up. The disease manifests in the form of vaginal discharge with or without itching. It has a strong association with preterm labor, preterm premature rupture of membranes and low birth weight in pregnancy. The objective of this study was to find out the prevalence of bacterial vaginosis among the reproductive age group women, in a tertiary care centre.Methods: A cross sectional study was conducted among 150 women of the reproductive age group in the department of obstetrics and gynaecology Sree Mookambika Institute of Medical Sciences over a period of one month October 2018 the diagnosis was made with history and nugents scoring system.Results: Out of the total 150 women enrolled in the study 74 had positive results, 50% of them were of the age group 26-30.Conclusions: The study shows us the high prevalence of bacterial vaginosis.

scholarly journals A clinical study of ectopic pregnancy in a tertiary care hospital

2018 ◽  
Vol 7 (11) ◽  
pp. 4461
Author(s):  
Arati Behera ◽  
Ranjita Ghadei ◽  
Rudra Narayan Bal
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
Tertiary Care ◽  
Medical Practitioner ◽  
High Risk Group ◽  
Reproductive Age ◽  
Common Symptom ◽  
Care Hospital ◽  
Age Group ◽  
Future Fertility

Background: Ectopic pregnancy is a life-threatening emergency commonly encountered by medical practitioner. Diagnosis is frequently missed and should be considered in any women in the reproductive age group with abdominal pain or vaginal bleeding. The aim of the study is to assess the incidence, clinical presentation, risk factors, methods of diagnosis, treatment, outcome and complications.Methods: This was a prospective study at S.C.B. Medical college from January to December 2017. Parameters like age, parity, gestational period, risk factors, clinical presentations, findings on ultrasonogram and at surgery with morbidities associated with diagnosed cases of ectopic pregnancy (n=93) were noted and analysed with SPSS-19 software.Results: Incidence of ectopic pregnancy was 18/1000 deliveries. Maximum cases were in age group of 21 to 30 years (54.8 %) and parous (76.3%). Common risk factors were having history of abortions (46.2%), previous tubal sterilization (24.7%), having one or more caesarean section (17.2%) and h/o infertility (16.1%). Most common symptom was pain abdomen (96.8%). Commonest site was ampullo-isthmic region of tube and rupture was the commonest mode of presentation. All underwent laparotomy and unilateral salpingectomy was done in 86 % of cases. It contributed to 3.27 % of total maternal deaths.Conclusions: Suspicion in high risk group can direct one to investigate and diagnose early, thereby reducing morbidity, mortality and improving the prospect of future fertility.

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