scholarly journals Current trends of consanguineous marriages and its association with socio-demographic variables in Pakistan

Author(s):  
Fouzia Zahid Ali Khan ◽  
Syeda Batool Mazhar

Background: A high proportion of marriages in South and Middle East Asia are contracted between close biological relatives due to cultural preference as it is a deeply rooted social fashion among these societies. The aim of this study was to determine the frequency of consanguineous marriages and ascertain their relationship to relevant sociodemographic variables.  Methods: This was a cross sectional descriptive study conducted in tertiary care hospital of Islamabad. Data were collected on a specially designed questionnaire form. Age of participants, their education, socioeconomic status, castes and number of anomalous children born to these participants, degree of consanguinity and reasons of preferences were inquired.  Results: Out of 300 women chosen by convenience sampling technique, 62% had consanguineous marriages, and 38% had a non-consanguineous union. The mean age of women presenting to maternal and child health centre was 27 years. The average age of a woman having consanguineous marriage was 21 years in contrast to 24 years for non-consanguineous nuptial. About 18% of women in consanguineous marriages were illiterate as compared to 5.4% (p = 0.001) of women in non-consanguineous unions. First cousin marriages were more common among certain castes like Rajput and Awan. None in the consanguineous group had any anomalous baby in contrast to non-consanguineous who had two anomalous children (p = 0.0001). There was no significant association between type of marriage and the number of miscarriages (p=0.69).Conclusions: This study showed UA-S/D ratio and UA-RI>2SD are significant predictors of perinatal deaths and immediate neonatal resuscitation in preeclampsia. Acute fetal distress in labour or neonatal nursery admission could not be predicted.

Author(s):  
Urooj Zafar ◽  
Zahida Memon ◽  
Kausar Moin ◽  
Shanza Agha ◽  
Jahan Ara Hassan ◽  
...  

Aim: The aim of this study is to determine the prevalence of PCOS among different gynecological disorders at tertiary care hospital of Karachi and to assess the most frequent presenting complaint with associated complications among them. Study Design: Single-centered cross-sectional study. Place and Duration of Study: Gynecological clinic of Karachi at a Tertiary care Hospital during 3rd December 2018 to 29th March 2019. Methodology: Total 335 premenopausal women approached the clinic with different gynecological disorders during the period of four months and 305 patients agreed to participate. The patients were enrolled via convenient sampling technique. After taking the informed consent they were evaluated through clinical interviews, questionnaire, and anthropometric measurements. The diagnosis of PCOS was made by using Rotterdam criteria 2003. Menstrual irregularities were assessed via history. Clinical hyperandrogenism was evaluated by using modified Ferriman–Gallwey scale and Acne Global Grading System. Obesity was calculated through BMI. The Hamilton scale was used to appraise associated psychological disturbances. Results: PCOS was the most prevalent gynecological disorder (55.41%) among women of the premenopausal age. Overall, the most frequent presenting complaint was infertility but age related variations in symptoms showed that young adolescent and adulthood had more menstruation irregularities while, in late adolescent the chief complaint was infertility. Moreover, these patients were either overweight 32% or obese 46.2%. Other associated problems such as anxiety and migraine were more frequent in young adults and juveniles respectively. Conclusion: PCOS is the most common gynecological problem in our region. These women usually presents with altered complains that influence their physiological and psychological health which in turn effects the quality of life.


2016 ◽  
Vol 07 (02) ◽  
pp. 250-256 ◽  
Author(s):  
Vishnu Renjith ◽  
Mamatha Shivananda Pai ◽  
Flavia Castelino ◽  
Aparna Pai ◽  
Anice George

ABSTRACT Background: Migraine is a common disabling primary headache disorder. Globally, migraine was ranked as the seventh highest cause of disability. Aim: The aim of the study was to explore the clinical profile and functional disability of patients with migraine. Settings and Design: A cross-sectional survey was conducted at the neurology outpatient department of a tertiary care hospital in Karnataka. Materials and Methods: Using a consecutive sampling technique, 60 patients were recruited for the study. Descriptive and inferential statistics were used to analyze the data. Results: Majority of the participants were in the age group of 18–40 years with a mean age 35.22 years. There was a female preponderance with 70% of study participants being females. The various symptoms experienced by patients include throbbing pain (90%), photophobia (93.3%), phonophobia (85%), nausea (76.7%), and vomiting (41.7%). Most of the subjects (73.3%) under the study belonged to moderate to severe levels of functional disability. About 53.3% of patients were in the category of episodic migraine and 46.7% were in the category of chronic migraine. Conclusion: Migraine is associated with moderate to severe functional disability. Frequency of migraine has a positive correlation with the levels of disability/migraine disability assessment scores of migraineurs.


Author(s):  
Paras V. Dobariya ◽  
Parul T. Shah ◽  
Hina K. Ganatra

Background: Fetal, Neonatal and Maternal complications associated with pregnancy beyond 40 weeks have always been underestimated. However emerging evidence demonstrates that the incidence of complications increases after 40 weeks of gestation. The present study conducted to find out the fetomaternal outcome of such prolonged pregnancy.Methods: A prospective cross sectional study of 84 patients with uncomplicated prolonged pregnancy fulfilling the inclusion and exclusion criteria and admitted in department of obstetrics and gynecology at a tertiary care hospital. The aim of the study was to know fetomaternal outcome in pregnancy beyond 40 weeks in consideration of spontaneous and induced labour.Results: Out of 84 patients, 58 (69.05%) were in the age group of 20-30 years, 44 (52.38%) were between 41-42 weeks of gestation according to their LMP and 38(45.24%) were between 40-41 weeks of gestation. In 27 (32.14%) patients mode of delivery was caesarean section, in whom most common indication being fetal distress in 48.15% followed by failure to progress in 22.22%. In present study perinatal morbidity like IUFD, neonatal asphyxia, MAS, RDS were 4.76%, 9.52%, 7.14% and 3.57% respectively. Maternal morbidity like prolonged labor, PPH, fever, wound infection were 10.71%, 5.95%, 3.57% and 3.57% respectively.Conclusions: With Regular antenatal check-up, incidence of postdate pregnancy can be decreased and it is important because of definite risk to fetus as pregnancy continuing beyond 40 weeks of gestation is associated with increased perinatal morbidity and mortality especially those who do not come for regular antenatal check-up. Confirmation of diagnosis of exact term of pregnancy is very important as many patients don’t have regular menstrual history and LMP. Diagnosis can be confirmed by first trimester ultrasound which is most important non-invasive method and readily available.


2019 ◽  
Vol 9 (2) ◽  
pp. 69-72
Author(s):  
Zulfiqar Ali Shaikh ◽  
Afifa Yaseen ◽  
Amna Yaseen ◽  
Subhana Akber

Background: Panoptic knowledge of dental professionals is required to provide care for patients with any dental problem which ranges from screening, emergency care or referral to alleviation of pain symptoms. Ideally to provide dental care, dental practice should be based on current clinical concepts originating from evidence-based dentistry which clearly demarcates a level between a tooth that is able to be restored so that intervention is done on it for esthetic and functional stability, or ready for extraction. Dental professionals' knowledge regarding tooth restorability is very crucial in restorative and preventive dentistry. The aim of this study was to assess the knowledge of dental professionals regarding tooth restorability. Methods: Knowledge regarding tooth restorability of dental professionals of Dow University of Health Sciences was assessed through a multi centered cross sectional study. A sample size of 140 participants was calculated using through open Epi version 3, and a convenient non-probability sampling technique was used. The study was conducted in May-June, 2018. An informed consent prior to the study was taken. The dental professionals were evaluated through a self- administered, structured questionnaire in English. The SPSS-23 was used to obtain results. The knowledge of the students was graded as adequate if >12 and inadequate if<12. Results: Out of 140 study participants, 113 (81%) dental professionals had significantly adequate knowledge (p-value <0.05); while 27 (19%) had inadequate knowledge. Among the respondents, 56% said that the traumatic dental injury must be treated by dentist whereas the others considered it to be treated by private doctor or by nearest hospital casualty. Conclusion: The knowledge of dental professionals working at teaching institutes is adequate; and as per their knowledge they might be taking right decisions regarding tooth restorability.


2012 ◽  
Vol 30 (2) ◽  
pp. 78-84
Author(s):  
L Khondker ◽  
AM Choudhury ◽  
MOR Shah ◽  
M Shahidullah ◽  
MSI Khan ◽  
...  

A cross sectional study, conducted in the department of  Dermatology and Venereology, Bangabandhu Sheikh Mujib  Medical University (BSMMU) for duration of January 2009  to December 2010. Hundred twenty patients with  onychomycosis were selected by purposive type of nonprobability  sampling technique. Majority of the patients  61(150.8%) were in the age group of 21-30 years old. Mean  age of the patients were 32.8±14 years and most of the  patients were house wives 36(30.0%). Disfigurement  117(97.5%) and discomfort 89(74.2%) were more common  chief complaints of the patients. The mean duration of  disease was 20.4±15.4 months and nail fold changes were  associated with 37(30.8%) patients and more than a half  63(52.5%) of the patients had history of wet works.  Regarding the history of past illness, it was observed that  previous onychmycosis found 26(21.7%), nail trauma  26(21.7%) and immune suppression 6(5.0%). In  endocrinopathies, hypothyroidism was observed in 1(0.8%),  Diabetes Mellitus 6(5.0%) etc. Regarding the pattern of nail  changes, thickening of nail plate 88(73.3%), onycholysis  67(55.8%), subungunal hyperkeratosis 61(50.8%) were  more common changes. Paronychia was observed in 34  (28.3%) cases. In concomitant fungal infection, it was  observed that T. manuum in 6(5.0%), T. pedis 3(2.5%),  Interdigital intertrigo 2(1.7%) and T. cruris 1(0.8%). This  was a study on a limited number of cases. Future studies  must include economical support, then large sample size  could be ensured and study finding would be more reliable.  There is a great need of epidemiological studies also, with  sufficient follow-up, systematic reviews and meta-analyses  on this issue.   DOI: http://dx.doi.org/10.3329/jbcps.v30i2.11408   J Bangladesh Coll Phys Surg 2012; 30: 78-84    


2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Monika Pokharel ◽  
Bikash Lal Shrestha ◽  
Dharmendra Karn ◽  
Ashish Dhakal ◽  
Abha Kiran K.C. ◽  
...  

Introduction: The prevalence of allergic rhinitis has increased significantly globally over the last two decades. Detection of sensitizing aeroallergens plays a crucial role in the diagnosis and management of this troublesome disease. This study aims to investigate the spectrum of aeroallergens sensitization in patients with allergic rhinitis in a tertiary care hospital. Methods: A descriptive cross-sectional study conducted in the Department of Otorhinolaryngology of our hospital between January 2016 to December 2019. Ethical approval was taken from the Institutional Review Committee (No: 210/19). Patients diagnosed with allergic rhinitis were enrolled using the convenience sampling technique. Data entry and analysis was done using IBM Statistical Package for Social Sciences version 20.0. Results: Among 170 patients, altogether 103 (60.6%) patients yielded positive responses on the skin prick test. The most prevalent aeroallergens were Lepidoglyphus 86 (50.60%), Dermatophagoides pteronyssinus 85 (50%), Dermatophagoides farina 82 (48.20%), Thyrophagus 50 (29.40%), Blomia 46 (27.10%), Acarus 43 (25.30%), cat dander 26 (15.30%), dog dander 24 (14.10%), cow and buffalo dander 20 (11.8%), ragweed 20 (11.8%), grass pollen 18 (10.60%) and mugwort 17 (10%). Conclusions: This study highlights that the frequency of aeroallergens based on skin prick test in patients presenting to a tertiary care hospital which showed the dominance of house dust mites, dog and cat hair, pollen, and grasses. Reduced exposure and training of patients about protection against these agents will possibly help in controlling the severity of allergic rhinitis in this region.


2020 ◽  
Vol 24 (2) ◽  
Author(s):  
UZMA KHURSHEED ◽  
MUHAMMAD HUSSAIN ◽  
SYED AMIR GILANI

Objective:  Hands play a significant role in organism transmission. Poor hand hygiene practices in health care settings lead to nosocomial infection. Aseptic practice is the cornerstone of current surgery, thus rigid adherence to prescribed sterile techniques in the operating room is essential.The objective of this study was to evaluate nurses’ competencies regarding surgical hand scrubbing. Material and Methods: Cross sectional observational design was used. The study was conducted in operating rooms in a tertiary care hospital, Lahore, Pakistan.This setting contains total seven operating rooms with 250 registered nurses. Sample size calculated through Slovin’s formula. Sample size was 154. Convenient sampling technique was used. An adopted checklist was used for observing the nurses’ practices of hand scrubbing. Data was analyzed in Statistical Software of Social Sciences (SPSS) version 25. Results:  Majority of nurses (72.7%) were between 21-30 years age group. Only 38.3% participants wore a face mask and surgical cap correctly and 61.7% did not wear correctly. Majority participants, 76% had short nails.All participants (100%) removed nail polish, artificial nails, and jewelry before scrubbing. Majority of participants applied a proper amount of Povidone iodine. Conclusion:  Operational hand scrub is very vital component of operative procedure. Results of this study showed inadequate practices of nurses in the operating room, which was overall 77%. There is a need to improve nurses’ practices so, periodically audit, manager supervision and feedback, workshops should be organized.


2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Ayesha Muneer ◽  
Attia Bari ◽  
Arslan Haider ◽  
Agha Shabbir Ali

Objective: To analyze the knowledge of the doctors dealing with pediatric patients about neonatal resuscitation. Methods: This was a cross sectional study conducted at The Lahore General Hospital over one year. Total 137 doctors related to pediatrics with different job descriptions were enrolled and requested to fill a questionnaire proforma regarding their knowledge about basic equipment required and about neonatal resuscitation steps. Data was entered and analyzed using SPSS 20. Results: Out of 137 participants, majority (71%) had >2 years of experience in pediatrics and 52.5% had higher postgraduate qualification. Neonatal resuscitation workshop was attended by 57% doctors. In resuscitation of newborns at the time of delivery, resuscitating doctors were assisted by nurse in 50%, by junior doctor in 35%, paramedic staff 11% and it was done by single doctor in 4% cases. Oxygen (central or O2 cylinder) and warmer facilities were available in 90% and 82% of health facilities respectively. Majority (86%) of participants were of view that every neonate must be attended at birth. Not a single doctor followed all the standard steps of neonatal resuscitation although 90% had knowledge about resuscitation equipment and common resuscitation drugs. Conclusion: Pediatric health care professionals had knowledge about neonatal resuscitation but there are gaps in the practical application. There is a strong need of frequent neonatal resuscitation workshops for improving neonatal outcomes. doi: https://doi.org/10.12669/pjms.35.3.987 How to cite this:Muneer A, Bari A, Haider A, Ali AS. Knowledge of clinicians/pediatricians about neonatal resuscitation in a tertiary care hospital. Pak J Med Sci. 2019;35(3):---------. doi: https://doi.org/10.12669/pjms.35.3.987 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 27 (12) ◽  
pp. 2574-2580
Author(s):  
Imran Nazir Ahmad

Objectives: To see the prevalence and outcome of Human brucellosis in Makkah. Study Design: Retrospective Cross Sectional study. Setting: Security Forces Hospital, Makkah. Period: August 2016 to August 2019. Material & Methods: Patient's data was collected for the last 3 years. Simple randomized sampling technique was adopted and data was collected and analyzed using SPSS version 24. Univariate comparisons were done by using Chi square test. Results: This study enrolled 241 patients with predominant age group of 15-40 years (41.9%). Incidence rate in Makkah is 4.01 per 100,000 persons per year. Male were predominant (67.2%). About fifty-seven (57.3) % patients belonged to urban areas and the risk of acquisition of brucellosis was the consumption of unpasteurized milk in 138 (57.3%) patients. Most common clinical presentation was fever (95.4%) without a definite focus in 200 patients (83%), Eighty-three (83%) patients had uncomplicated brucellosis. The most common (67.2%) treatment regimen was rifampicin and doxycycline for 6 weeks. Relapse rate was reported 10.8%. Death rate was reported to be 0.9%. Conclusion: Brucellosis still affects health of Saudi population and causes economic burden. It is recommended to keep up the efforts to decrease the brucellosis incidence rate toward zero.


2020 ◽  
pp. 1-2
Author(s):  
Arer AR ◽  
Hulagbali M

A study was conducted on 90 children suffering with thalassemia who are attending thalassemia unit of KLES Dr. Prabhakar Kore Charitable Hospital Belagavi. To assess the health related quality of life of children with thalassemia and to find out the association between health related quality of life of children with Thalassemia and selected demographic variables. Purposive sampling technique was used to select the samples. Data was collected using standardized paediatric inventory quality of life (PedsQL 4.0 Generic Core Scales) tool. Data obtained was tabulated and analysed in terms of objectives of the study using descriptive and inferential statistics. The study revealed that Majority 70 (77.78%) of thalassemia children had average level of quality of life where as minimum 10 (11.11%) of thalassemia children had low and high level of quality of life. The association between age groups and levels of QOL is found to be not statistically significant (Chi-square= 6.3530, p=0.1740) and the association between religions and levels of QOL is found to be not statistically significant.


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