scholarly journals Study of pregnancy outcome of threatened abortion and its correlation with risk factors in a tertiary care hospital of Mumbai, India

2018 ◽  
Vol 7 (11) ◽  
pp. 4598
Author(s):  
Dipali S. Sivasane ◽  
Rekha G. Daver
Keyword(s):  
Risk Factors ◽  
Maternal Age ◽  
Pregnancy Loss ◽  
Demographic Data ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Number Of Patients ◽  
Significant Difference ◽  
Threatened Abortion

Background: Early pregnancy loss is very common and, in most cases, it can be considered as nature’s method to select for a genetically normal offspring. Threatened abortion is a relatively common complication during pregnancy, occurring in approximately 20% of all pregnancies. Maternal age, Outcome of previous pregnancies, health of mother, any infection etc can be decisive factors in the risk of pregnancy loss.Methods: The present study was a cross sectional study where patients admitted with threatened abortion were interviewed using pretested semi-structured questionnaire after the treatment. Outcome of pregnancy was recorded. Their basic socio-demographic data along with possible risk factors were recorded. TORCH Ig M and Ig G were done in all patients.Results: Out of 95 patients admitted with threatened abortion, 42 (44%) patients undergone abortion whereas in 53 (56%) patients, pregnancy was continued. Out of total 60 patients admitted with the complain of only vaginal spotting, in 39 pregnancy continued and in 21 patients pregnancy was aborted. (p-value<0.05). 50.52% were from age group of 21 to 25 years of age. It was also seen that after 35 years of age, significant number of patients aborted. Out of these 11 patients with high BMI, pregnancy was continued only one patient. Out of total 20 patients positive for IgM of toxoplasma infection, pregnancy was aborted in 13 (65%) patients. Out of total 15 patients positive for IgM of cytomegalo virus infection, pregnancy was continued in 11 (73.3%) patients.Conclusions: Patients of threatened abortion with only symptom of spotting per vagina have good chances of continuation of the pregnancy. Increased maternal age above 35, Overweight and bad obstetric history are also associated with pregnancy loss. Though there was no statistically significant difference it was evident that among all TORCH infections, IgM toxoplasma and Rubella are associated more with pregnancy loss.

scholarly journals ASSESSING THE RISK FACTORS OF WORK-RELATED STRESS AMONG HOUSE OFFICERS OF TERTIARY CARE HOSPITALS, KARACHI

2018 ◽  
Vol 8 (2) ◽  
pp. 117-122
Author(s):  
Zulfiqar Ali Shaikh ◽  
Noshaba Noor ◽  
Aisha Farooq ◽  
Maryam Khaleel ◽  
Darakhshan Naqvi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Perceived Stress ◽  
Demographic Data ◽  
Tertiary Care ◽  
P Value ◽  
Work Related Stress ◽  
Work Related ◽  
Significant Difference ◽  
Related Stress ◽  
Tertiary Care Hospitals

Background: House Officers report significant levels of work-related stress that demands to be immediately addressed as it adversely affects their ability to function their best as doctors. This study aimed to assess the risk factors of psychological distress among the currently working house officers (2016-2017). Objectives: To assess the various risk factors of work-related stress amongst the house officers working in tertiary care hospitals, Karachi Methods: A cross sectional study was carried out in Civil Hospital, Jinnah Postgraduate Medical Centre and Abbasi Shaheed Hospital, Karachi during October 2016 and March 2017. A total of 384 house officers were approached for the study as per the sample size calculated using the Open-epi software. The questionnaire comprised of demographic data, 10-items perceived stress scale, and 12-items list of potential stressors. The severity of each stressor was measured using a five-point Likert scale (1-5) ranging from always (1) to never (5). Results: A total of 384 house officers were approached out of whom 315 (82%) participated. Among them, 115 (36.50%) were found to be under stress of whom 24 (20.8%) were males and 91(79.2%) were females. Significant difference for stressors by gender was found, these included their job having an effect on their health, change in eating habits and lack of paramedical staff cooperation (P < 0.05). Factors like increased hesitancy to take on tasks and increased tendency to make errors were found to have an impact on clinical performance (P value <0.05). Conclusion: There is high level of perceived stress in house officers of tertiary care hospitals, Karachi. Therefore, adequate steps are needed for stress management which should be dealt in terms of preventive rather than curative strategy.

Risk Factors Associated with Peritoneal Involvement in Acute appendicitis in Territory of Punjab, Pakistan

2021 ◽  
Vol 15 (11) ◽  
pp. 3076-3077
Author(s):  
Fauzia Siraj ◽  
Rabbiah Manzoor Malik ◽  
Zafar Iqbal ◽  
Rifat Shamim ◽  
Attya Zaheer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Appendicitis ◽  
Tertiary Care ◽  
Previous History ◽  
P Value ◽  
Care Hospital ◽  
Factors Associated ◽  
Time Of Surgery ◽  
Number Of Patients ◽  
History Of

Aim: To study the frequency and factors associated with peritoneal involvement among patients operated for acute appendicitis in a tertiary care hospital. Place and duration of study: Department of Surgery, Benazir Bhutto Hospital Rawalpindi Pakistan from 1stJuly 2020 to 30thJune 2021. Methodology: This comparative cross-sectional study 500 patients diagnosed as acute appendicitis and operated by consultant surgeon were included. Peritoneal involvement was defined as signs of inflammation or infection on abdominal lining observed by operating surgeon during the time of surgery. Factors like age, gender, presence of comorbid illnesses and history of previous abdominal surgeries were associated with presence of peritoneal involvement. Results: There were 305 (61%) males while 195 (39%) were females with mean age was 32.331±4.544 years.Four hundred and forty two (88.4%) did not show any peritoneal involvement at the time of surgery while 58 (11.6%) had peritoneal involvement. Chi-square test revealed that history of previous abdominal surgeries and advancing age had statistically significant association with peritoneal involvement among the study participants (p-value<0.05). Conclusion: Peritoneal involvement was found in considerable number of patients operated as acute appendicitis by the treating surgeons. Patients with previous history of abdominal surgeries and advancing age were more at risk of having peritoneal involvement in our study. Keywords: Acuteappendicitis, Peritonitis, Risk factors, Frequency

scholarly journals COMPARATIVE STUDY ON PREVALENCE AND ASSESSMENT OF ALTERED SENSORIUM AMONG SODIUM ABNORMALITY PATIENTS AT A TERTIARY CARE TEACHING HOSPITAL

2021 ◽  
Vol 10 (6) ◽  
pp. 3837-3839
Author(s):  
G.N Sharma
Keyword(s):  
Serum Sodium ◽  
Tertiary Care ◽  
Plasma Sodium ◽  
P Value ◽  
Care Hospital ◽  
Altered Level ◽  
Altered Sensorium ◽  
Number Of Patients ◽  
Significant Difference ◽  
Level Of Consciousness

Altered sensorium or altered level of consciousness is a common complaint among electrolyte abnormality patients and has several synonyms like altered behaviour, generalized weakness, lethargy, agitation, psychosis, disorientation, inappropriate behaviour, inattention, confusion, hallucination. The aim of the study was to evaluate the prevalence and to assess the level of consciousness dysnatremic patients at a tertiary care hospital. A prospective observational study, serum sodium level and other clinical profiles were recorded in a data collection form. GCS was used to analyses the level of consciousness among the enrolled patients. SPSS 22.0 statistical software was used for data analysis. During the study period, a total of 482 patients were enrolled in the study. Based on the serum sodium, they were categorized into Hyponatraemic (410) and Hyponatraemic (72) patients. Our study found a greater number of patients in the age group above 60 years and found that sodium imbalance increases generally in males with increasing age. Our study found that altered sensorium (60%) was predominant more in hyponatremia patients. Chi square test was performed to find statistically significant difference in level of consciousness between hypo and Hyponatraemic patients and was found to be significant p value (≤ 0.05). Abnormalities of plasma sodium are probably the most common electrolyte disorders and they are associated with serious morbidity including a poorer long-term neurologic outcome.

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in hospitalized patients at a tertiary referral center in North India (Preprint)

2020 ◽  
Author(s):  
Dr. Animesh Ray ◽  
Dr. Komal Singh ◽  
Souvick Chattopadhyay ◽  
Farha Mehdi ◽  
Dr. Gaurav Batra ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Hospitalized Patients ◽  
North India ◽  
P Value ◽  
Care Hospital ◽  
Igg Antibodies ◽  
Igg Antibody ◽  
Increased Risk ◽  
Significant Difference

BACKGROUND Seroprevalence of IgG antibodies against SARS-CoV-2 is an important tool to estimate the true extent of infection in a population. However, seroprevalence studies have been scarce in South East Asia including India, which, as of now, carries the third largest burden of confirmed cases in the world. The present study aimed to estimate the seroprevalence of anti-SARS-CoV-2 IgG antibody among hospitalized patients at one of the largest government hospital in India OBJECTIVE The primary objective of this study is to estimate the seroprevalence of SARS-CoV-2 antibody among patients admitted to the Medicine ward and ICU METHODS This cross-sectional study, conducted at a tertiary care hospital in North India, recruited consecutive patients who were negative for SARS-CoV-2 by RT-PCR or CB-NAAT. Anti-SARS-CoV-2 IgG antibody levels targeting recombinant spike receptor-binding domain (RBD) protein of SARS CoV-2 were estimated in serum sample by the ELISA method RESULTS A total of 212 hospitalized patients were recruited in the study with mean age (±SD) of 41.2 (±15.4) years and 55% male population. Positive serology against SARS CoV-2 was detected in 19.8%patients(95% CI 14.7-25.8). Residency in Delhi conferred a higher frequency of seropositivity 26.5% (95% CI 19.3-34.7) as compared to that of other states 8% (95% CI 3.0-16.4) with p-value 0.001. No particular age groups or socio-economic strata showed a higher proportion of seropositivity CONCLUSIONS Around, one-fifth of hospitalized patients, who were not diagnosed with COVID-19 before, demonstrated seropositivity against SARS-CoV-2. While there was no significant difference in the different age groups and socio-economic classes; residence in Delhi was associated with increased risk (relative risk of 3.62, 95% CI 1.59-8.21)

scholarly journals ACUTE MYOCARDIAL INFARCTION;

2013 ◽  
Vol 20 (03) ◽  
pp. 332-340
Author(s):  
ATIF SITWAT HAYAT ◽  
MUHAMMAD ADNAN BAWANY ◽  
JAWAD AHMED QADRI ◽  
Kiran Khalil
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Heart Block ◽  
Complete Heart Block ◽  
Tertiary Care ◽  
Anterior Wall ◽  
P Value ◽  
Inferior Wall ◽  
Care Hospital ◽  
Significant Difference

Background: Ischemic heart disease is the most common cause for complete heart block (CHB) and sudden death. Heartblocks may occur as complications of acute myocardial infarction (AMI) and are associated with increased mortality. The aim of thisstudy is to determine the frequency of complete heart block (CHB) in acute myocardial infarction at a tertiary care hospital. Place andduration: This study was conducted in Cardiology Department of Liaquat University of Medical and Health Sciences from 1st August2009 to 31st January 2010. Study Design: Cross sectional and descriptive study. Materials and Methods: ST segment elevation equal toor more than 1mm (0.1mv) in two of these leads II, III and aVF. Rise in serum creatinine kinase level (CPK Level) more than twice thenormal value along with CK-MB fraction more than 6% of CPK value. Patients with history of chest pain, shortness of breath, nausea,vomiting and unconsciousness were enrolled in the study. The cardiac enzymes tropinin T was also performed at bed side by venousblood sample. Results: Total of 87 patients were included, prevalence of heart blocks was 27.58%. Anterior wall MI was in 50(57.5%)patients. Of these, 13(54.2%) had complete heart block. Inferior wall MI was in 37(42.5%) cases, of these, 11(45.8%) were found withcomplete heart block. There was no significant difference between anterior wall MI and inferior wall MI with complete heart block (P value> 0.05). Mortality was 2.3% with anterior wall MI. Conclusions: Development of complete heart blocks has important prognosticsignificance. Complete heart block was frequent complication of myocardial infarction.

scholarly journals Risk factors, clinico-epidemiological profile of tuberculosis among children attending a tertiary care hospital: a two year study

2018 ◽  
Vol 5 (3) ◽  
pp. 851
Author(s):  
Ravikumar Tenali ◽  
Naveen Kumar Badri ◽  
Jithendra Kandati ◽  
Munilakshmi Ponugoti
Keyword(s):  
Risk Factors ◽  
Clinical Features ◽  
Tertiary Care ◽  
Epidemiological Surveillance ◽  
P Value ◽  
Tuberculous Lymphadenitis ◽  
Care Hospital ◽  
Female Ratio ◽  
Extra Pulmonary ◽  
Epidemiological Profile

Background: TB remains as the one among the top 10 causes of death worldwide. In 2016, 10.4 million people fell ill with TB, and 1.7 million died from the disease with 0.4 million with HIV. At least 1 million children become ill with TB each year. Children represent about 10-11% of all TB cases. Having knowledge of the risk factors for tuberculosis infection in children is important to evaluate the level of ongoing transmission of infection and to help adapt activities within national TB control programs. The main objective is to study the risk factors and their association and variable clinical features in cases of pulmonary and extra pulmonary tuberculosis.Methods: The main objective is to study the risk factors and their association and variable clinical features in cases of pulmonary and extra pulmonary tuberculosis.Results: 98 cases of TB were confirmed out of total 628 with a prevalence of 17.07% in the   study with 78 PTB cases and 20 EPTB. Females were more with male to female ratio of 0.7:1.5-9 years was the most common age group in the study. Statistically significant association was found between old history of ATT, HIV positivity, contact with an open case of TB and malnutrition (p value<0.05). TB meningitis was the most common EPTB (10/20 cases) followed by tuberculous lymphadenitis (5/20). 69.39% (68/98 cases) were smear positive, radiologically 59.18% of cases were positive and Tuberculin skin test was positive in 46.94%.Conclusions: Childhood tuberculosis is a neglected entity in developing countries due to underreporting and difficulties in diagnosis due to variable clinical picture in children. Hence epidemiological surveillance studies in children are required to determine the actual prevalence of pulmonary and extra pulmonary cases of tuberculosis. Increased efforts are required to isolate TB bacilli from body fluids to identify early the childhood cases and manage them to prevent disease burden in the community.

Surgical-site infections in emergency abdominal paediatric surgeries at a tertiary-care hospital in Pakistan

2020 ◽  
pp. 1-9
Author(s):  
Ali Faisal Saleem ◽  
Huma Faiz Halepota ◽  
Hasaan Omar ◽  
Areeba Zain ◽  
Muhammad Arif Mateen Khan
Keyword(s):  
Abdominal Surgery ◽  
Surgical Site Infection ◽  
Tertiary Care ◽  
Stable Condition ◽  
University Hospital ◽  
P Value ◽  
Care Hospital ◽  
Site Infection ◽  
Significant Difference ◽  
Pathogen Occurrence

Abstract A retrospective chart review was carried out in children (neonates to 18 years) who underwent acute surgical abdominal exploration during 2012-2016 at the Aga Khan University Hospital, Karachi, to evaluate the post-operative surgical site infection rates in emergency paediatric abdominal surgery. Incidence of surgical site infection (SSI) was estimated. P-value was calculated, chi-square and non-parametric tests were performed by comparing pre-surgical and post-surgical procedure pathogen occurrence and pre-procedure wound status. Pathogen occurrence related to time-trend of 98 paediatric patients who underwent emergency abdominal surgery was plotted. Of the 94 who were discharged in stable condition, it was found that there was no significant difference between pre- and post-surgical pathogens. Escherichia coli (n=10) was found to be the most common pathogen. Contaminated wounds were associated with higher SSI (p=0.036, OR 1.95 95% CI 0.7-5.4). Continuous...  

scholarly journals Clinicopathological Evaluation of Seronegative Arthritis in a Tertiary Care Hospital of Bangladesh

2016 ◽  
Vol 12 (2) ◽  
pp. 66-70
Author(s):  
Md Shameem Haidar ◽  
Md Abdur Razzak
Keyword(s):  
Demographic Data ◽  
Tertiary Care ◽  
Armed Forces ◽  
Military Hospital ◽  
Inflammatory Rheumatic Diseases ◽  
Case Report Form ◽  
Care Hospital ◽  
Seronegative Arthritis ◽  
Cross Sectional ◽  
Number Of Patients

Introduction: The seronegative arthritis is a heterogeneous group of inflammatory rheumatic diseases with predominant involvement of axial, peripheral joints and enthesitis. All of these have some distinct as well as some overlapping features, characteristic peripheral asymmetrical lower limb involvement and a negative rheumatoid factor. Involvement of joints is usually oligoarticular but rarely polyarthritis may be present. Diagnosis is usually made from clinical features rather than investigations. Objective: To evaluate the seronegative arthritis clinicopathologically by collecting and analyzing the relevant informations. Materials and Methods: A descriptive cross-sectional prospective study was conducted at Combined Military Hospital, Chittagong from November 2015 to October 2016. A total 74 patients of suspected seronegative arthritis were included. Detail socio-demographic data were collected from the informant and recorded in structured case report form. Clinical examination and relevant investigations were done meticulously to confirm the aetiology of seronegative arthritis. Results: Maximum number of patients was in the 3rd to 4th decade (62.1%), mean age of the patient was 37.4±8.7 and 38.7±8.1 years in male and female respectively. Malefemale ratio was 2.65:1. Symmetrical sacroiliitis was found in 15(20.2%) patients, asymmetrical sacroiliitis in 36(48.6%) and in 23(31.2%) cases sacroiliac joint was not involved. Common aetiology for seronegative arthritis showed that, reactive arthritis recognized in majority of patients 29 (39.1%) and second most common cause was seronegative rheumatoid arthritis in 23(31%) patients. Conclusion: The Seronegative arthritis is a social, economical and health-care burden. Patients who develop 66 JAFMC Bangladesh. Vol 12, No 2 (December) 2016 arthritis have high disability, discomfort and loss of quality of life. Seronegative arthritis is an interesting group of related conditions with overlapping features and genetic and familial association. That may alert the primary care physician to attain possible diagnosis of spondyloarthritis and to consider a rheumatological opinion. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 66-70

scholarly journals Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Nighat Sultana ◽  
Attia Bari ◽  
Mehwish Faizan ◽  
Muhammad Sarwar
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Prognostic Factors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Neonatal Tetanus ◽  
P Value ◽  
Care Hospital

Objective: To determine the prognostic factors and outcome of tetanus in children of post-neonatal age admitted in the intensive care unit (ICU) of a tertiary care hospital. Methods: This prospective cross sectional study, carried out in the Pediatric ICU of The Children’s Hospital Lahore from Jan 2013 to March 2017. Children of both genders with age range of two months to 16 years diagnosed clinically as tetanus were included. All 132 patients were scrutinized for all possible risk factors, need for mechanical ventilation and outcome. Data was analyzed by SPSS version 20. Results: Mean age of children was 7.5±3.4 years with male predominance (70.5%). Only (38.6%) received three doses of vaccination but none had booster dose. Trauma (43.2%) encompassed maximum predisposing factor followed by ear or nose prick and ear discharge. Mean duration of ICU stay was 20±13.3 days. Mortality rate was (17.4%). Ventilator support was given to (78.8%). Neurological outcome was normal in (82.6%). Trauma, ear or nose prick in girls and ear discharge were significantly associated with poor outcome and death with p-value of <0.001, 0.011 and <0.001 respectively. Other factors associated with poor outcome were need for mechanical ventilation and neurological impairment with p-value of 0.001 and <0.001 respectively. Conclusion: Tetanus is causing our children to suffer from devastating disease. Vaccination status is not satisfactory and along with trauma, ear discharge and ear or nose prick are identifiable risk factors. To combat these issues large scale vaccination and booster doses remains promising option. doi: https://doi.org/10.12669/pjms.35.5.656 How to cite this:Sultana N, Bari A, Faizan M, Sarwar M. Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.656 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Endovascular Versus Open Versus Hybrid Revascularisation In Infra Inguinal Disease – 2 Years Prospective Study in A Tertiary Care Center in South India

2020 ◽  
Vol 11 (SPL2) ◽  
pp. 97-101
Author(s):  
Senthilnathan T. T. ◽  
Manoj Prabakar R. ◽  
Subramaniyan S. R. ◽  
Marunraj G. ◽  
Saravanan B. ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Statistical Significance ◽  
Care Center ◽  
Tertiary Care ◽  
Individual Risk ◽  
P Value ◽  
Acute Limb Ischemia ◽  
Number Of Patients ◽  
Treatment Procedures

Our aim is to share the clinical experience of , open and combined hybrid in infra inguinal disease and compare the results. A prospective study of 150 patients undergoing infra inguinal procedures was done, a period ranging from October 2017 to June 2019 with 3 months follow up. A number of patients undergoing CT , Digital Subtraction (DSA) were recorded. A number of cases undergoing Angioplasty, Catheter Directed (CDT), Open Surgical Bypass were noted. Cases of acute limb ischemia were excluded and chronic cases included in our study, age 35-85 years, sex distribution male 134(89.3%) and female 16(10.7%) cases. Similarly, individual risk factors were stratified. Ct was done in 60 (40%) and DSA in 90 (60%) cases. Diagnostic variables : left occlusion 42 (28%), right occlusion 55(36.7%), left tibial occlusion 18 (12%) and right tibial occlusion 35(23.3%). Treatment procedure variables : CDT and Angioplasty 1(0.7%), angioplasty 87(58%), angioplasty and bypass 8(5.3%), bypass 35(23.3%), CDT 15 (10%), CDT and bypass 4(2.7%). The results of the analysis were compared and statistical significance P-value were calculated by chi-square tests, SPSS software. Statistic significance was seen for risk factors CAD (0.001), Smoking (0.008), Hypertension (0.000) on comparison to treatment procedures and for corresponding clinical diagnosis (0.002), investigation modality (0.000) and treatment procedures.

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